JP2015529657A5 - - Google Patents

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Publication number
JP2015529657A5
JP2015529657A5 JP2015525760A JP2015525760A JP2015529657A5 JP 2015529657 A5 JP2015529657 A5 JP 2015529657A5 JP 2015525760 A JP2015525760 A JP 2015525760A JP 2015525760 A JP2015525760 A JP 2015525760A JP 2015529657 A5 JP2015529657 A5 JP 2015529657A5
Authority
JP
Japan
Prior art keywords
medicament
conditions
cancer
diseases
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015525760A
Other languages
English (en)
Japanese (ja)
Other versions
JP6374384B2 (ja
JP2015529657A (ja
Filing date
Publication date
Priority to EP12005716.1 priority Critical
Priority to EP12005716 priority
Application filed filed Critical
Priority to PCT/EP2013/002032 priority patent/WO2014023385A1/en
Publication of JP2015529657A publication Critical patent/JP2015529657A/ja
Publication of JP2015529657A5 publication Critical patent/JP2015529657A5/ja
Application granted granted Critical
Publication of JP6374384B2 publication Critical patent/JP6374384B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015525760A 2012-08-07 2013-07-10 プロテインキナーゼ阻害剤としてのピリドピリミジン誘導体 Active JP6374384B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP12005716.1 2012-08-07
EP12005716 2012-08-07
PCT/EP2013/002032 WO2014023385A1 (en) 2012-08-07 2013-07-10 Pyridopyrimidine derivatives as protein kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2015529657A JP2015529657A (ja) 2015-10-08
JP2015529657A5 true JP2015529657A5 (it) 2016-09-01
JP6374384B2 JP6374384B2 (ja) 2018-08-15

Family

ID=48782275

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015525760A Active JP6374384B2 (ja) 2012-08-07 2013-07-10 プロテインキナーゼ阻害剤としてのピリドピリミジン誘導体
JP2018076582A Pending JP2018150307A (ja) 2012-08-07 2018-04-12 プロテインキナーゼ阻害剤としてのピリドピリミジン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018076582A Pending JP2018150307A (ja) 2012-08-07 2018-04-12 プロテインキナーゼ阻害剤としてのピリドピリミジン誘導体

Country Status (10)

Country Link
US (1) US9725462B2 (it)
EP (1) EP2882746B1 (it)
JP (2) JP6374384B2 (it)
CN (1) CN104507942B (it)
AR (1) AR092365A1 (it)
AU (1) AU2013301865B2 (it)
CA (1) CA2881279A1 (it)
ES (1) ES2618004T3 (it)
IL (1) IL237073A (it)
WO (1) WO2014023385A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104271576A (zh) * 2012-02-23 2015-01-07 艾伯维公司 激酶的吡啶并嘧啶酮抑制剂
JP6374384B2 (ja) * 2012-08-07 2018-08-15 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung プロテインキナーゼ阻害剤としてのピリドピリミジン誘導体
KR20140027714A (ko) * 2012-08-27 2014-03-07 주식회사 홍인터내셔날 외부 디바이스와 연동하는 다트 게임 장치
KR20180028521A (ko) * 2015-07-21 2018-03-16 광저우 맥시노벨 파마수티컬스 씨오., 엘티디. 축합고리 피리미딘계 화합물, 중간체, 이의 제조 방법, 조성물 및 응용
CR20190339A (es) 2016-12-22 2020-01-10 Calithera Biosciences Inc COMPOSITIONS AND METHODS TO INHIBIT THE ACTION OF ARGINASE
WO2019014513A1 (en) * 2017-07-13 2019-01-17 Syros Pharmaceuticals, Inc. INHIBITORS OF KINASES TAM
WO2019100106A1 (en) * 2017-11-24 2019-05-31 The University Of Sydney Antibacterial compounds and methods of use thereof
WO2020188015A1 (en) 2019-03-21 2020-09-24 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3752141T2 (de) * 1986-02-24 1998-03-26 Mitsui Petrochemical Ind Mittel zur behandlung von neuropathie
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
AT237596T (de) 1996-02-13 2003-05-15 Astrazeneca Ab Chinazolinderivate und deren verwendung als vegf hemmer
KR100489174B1 (ko) 1996-03-05 2005-09-30 제네카-파마 소시에떼아노님 4-아닐리노퀴나졸린유도체
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
BR0111230A (pt) 2000-05-31 2003-06-10 Astrazeneca Ab Composto, e, uso e processo para a preparação do mesmo
CN1255391C (zh) 2000-07-07 2006-05-10 安吉奥金尼药品有限公司 作为血管破坏剂的colchinol衍生物
MXPA02012903A (es) 2000-07-07 2004-07-30 Angiogene Pharm Ltd COLQUINOL DERIVATIVES AS ANGIOGENESIS INHIBITORS.
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP2024342A2 (en) * 2006-05-01 2009-02-18 Pfizer Products Incorporated Substituted 2-amino-fused heterocyclic compounds
WO2008118823A2 (en) 2007-03-26 2008-10-02 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
US20110160232A1 (en) 2007-10-04 2011-06-30 Pingda Ren Certain chemical entities and therapeutic uses thereof
KR20170051521A (ko) 2008-04-16 2017-05-11 포톨라 파마슈티컬스, 인코포레이티드 syk 또는 JAK 키나제 억제제로서의 2,6-디아미노-피리미딘-5-일-카르복스아미드
AU2009243006B2 (en) 2008-05-01 2013-03-21 Sirtris Pharmaceuticals, Inc. Quinolines and related analogs as sirtuin modulators
TWI453207B (zh) 2008-09-08 2014-09-21 Signal Pharm Llc 胺基三唑并吡啶,其組合物及使用其之治療方法
KR20110093923A (ko) 2008-12-01 2011-08-18 메르크 파텐트 게엠베하 암에 대한 오토탁신 저해제로서의 2,5-디아미노-치환된 피리도 [4,3-d]피리미딘
CA2779105C (en) * 2009-10-29 2016-08-16 Hong Woo Kim Kinase inhibitors
CA2784830C (en) 2009-12-18 2018-03-27 Sunovion Pharmaceuticals Inc. Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
JP6374384B2 (ja) * 2012-08-07 2018-08-15 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung プロテインキナーゼ阻害剤としてのピリドピリミジン誘導体

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