JP2015528802A5 - - Google Patents
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- Publication number
- JP2015528802A5 JP2015528802A5 JP2015522098A JP2015522098A JP2015528802A5 JP 2015528802 A5 JP2015528802 A5 JP 2015528802A5 JP 2015522098 A JP2015522098 A JP 2015522098A JP 2015522098 A JP2015522098 A JP 2015522098A JP 2015528802 A5 JP2015528802 A5 JP 2015528802A5
- Authority
- JP
- Japan
- Prior art keywords
- her2 antibody
- fucose
- composition according
- her2
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261673216P | 2012-07-18 | 2012-07-18 | |
| US201261673229P | 2012-07-18 | 2012-07-18 | |
| US201261673201P | 2012-07-18 | 2012-07-18 | |
| US61/673,229 | 2012-07-18 | ||
| US61/673,201 | 2012-07-18 | ||
| US61/673,216 | 2012-07-18 | ||
| EP12197768 | 2012-12-18 | ||
| EP12197768.0 | 2012-12-18 | ||
| PCT/EP2013/065189 WO2014013019A1 (en) | 2012-07-18 | 2013-07-18 | Novel therapeutic treatments with anti-her2 antibodies having a low fucosylation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015528802A JP2015528802A (ja) | 2015-10-01 |
| JP2015528802A5 true JP2015528802A5 (enExample) | 2016-09-08 |
Family
ID=49948317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015522098A Pending JP2015528802A (ja) | 2012-07-18 | 2013-07-18 | フコシル化が低い抗ｈｅｒ２抗体を用いた新規治療処置 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20150166664A1 (enExample) |
| EP (1) | EP2874658A1 (enExample) |
| JP (1) | JP2015528802A (enExample) |
| KR (1) | KR20150036710A (enExample) |
| CN (1) | CN104394887A (enExample) |
| AU (1) | AU2013291964B2 (enExample) |
| BR (1) | BR112014032169A2 (enExample) |
| CA (1) | CA2875486A1 (enExample) |
| EA (1) | EA201590237A1 (enExample) |
| IL (1) | IL236714A0 (enExample) |
| MA (1) | MA37961A1 (enExample) |
| MX (1) | MX2015000730A (enExample) |
| NZ (1) | NZ701974A (enExample) |
| SG (1) | SG11201407841YA (enExample) |
| WO (1) | WO2014013019A1 (enExample) |
| ZA (1) | ZA201408938B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU92659B1 (en) * | 2015-02-23 | 2016-08-24 | Glycotope Gmbh | Glycooptimized antibody drug conjugates |
| US20200148785A1 (en) * | 2017-03-29 | 2020-05-14 | Glycotope (GmbH) | Pd-l1 and ta-muc1 antibodies |
| JP7273858B2 (ja) * | 2018-06-15 | 2023-05-15 | シャンハイ ミラコーケン インコーポレイティド | 癌を治療するための方法と材料 |
| CA3112043A1 (en) | 2018-09-10 | 2020-03-19 | Mirati Therapeutics, Inc. | Combination therapies |
| WO2020056338A1 (en) * | 2018-09-14 | 2020-03-19 | Prelude Corporation | Method of selection for treatment of subjects at risk of invasive breast cancer |
| CN113999313A (zh) * | 2020-07-28 | 2022-02-01 | 百奥泰生物制药股份有限公司 | 抗her2抗体及其应用 |
| CN116942809A (zh) * | 2023-03-03 | 2023-10-27 | 盛禾(中国)生物制药有限公司 | 一种抗her2抗体在制备治疗癌症的药物中的用途 |
| WO2026158510A1 (zh) * | 2025-01-24 | 2026-07-30 | 百奥泰生物制药股份有限公司 | 治疗实体瘤的联合疗法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0104865A3 (en) | 1999-01-15 | 2004-07-28 | Genentech Inc | Polypeptide variants with altered effector function |
| EP2275540B1 (en) | 1999-04-09 | 2016-03-23 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
| US7029872B2 (en) | 2000-06-28 | 2006-04-18 | Glycofi, Inc | Methods for producing modified glycoproteins |
| PL213948B1 (pl) | 2001-10-25 | 2013-05-31 | Genentech Inc | Kompozycje zawierajace glikoproteine, czasteczka kwasu nukleinowego kodujaca te glikoproteine, komórka gospodarza, sposób wytwarzania glikoproteiny, kompozycja do zastosowania do leczenia, zastosowanie kompozycji i zestaw zawierajacy kompozycje |
| CA2481920A1 (en) | 2002-04-09 | 2003-10-16 | Kyowa Hakko Kogyo Co., Ltd. | Antibody composition-containing medicament |
| KR101498588B1 (ko) * | 2003-01-22 | 2015-03-05 | 로슈 글리카트 아게 | 융합 구성체와 Ｆｃ 수용체 결합 친화도 및 이펙터 기능이 증가된 항체를 생성하기 위한 이의 용도 |
| FR2858235B1 (fr) | 2003-07-31 | 2006-02-17 | Lab Francais Du Fractionnement | Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs |
| JPWO2005053742A1 (ja) * | 2003-12-04 | 2007-06-28 | 協和醗酵工業株式会社 | 抗体組成物を含有する医薬 |
| WO2005086875A2 (en) * | 2004-03-11 | 2005-09-22 | City Of Hope | A humanized anti-cea t84.66 antibody and uses thereof |
| DOP2006000029A (es) * | 2005-02-07 | 2006-08-15 | Genentech Inc | Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas) |
| WO2008028686A2 (en) * | 2006-09-10 | 2008-03-13 | Glycotope Gmbh | Use of human cells of myeloid leukaemia origin for expression of antibodies |
| MX2012004029A (es) * | 2009-10-07 | 2012-05-08 | Macrogenics Inc | Polipeptidos que contienen la region fc que exhiben funcion efectora mejorada debido a alteraciones del grado de fucosilacion, y metodos para su uso. |
| US20120258496A1 (en) * | 2010-09-27 | 2012-10-11 | Boehringer Ingelheim International Gmbh | Production of low fucose antibodies in h4-ii-e rat cells |
-
2013
- 2013-07-18 WO PCT/EP2013/065189 patent/WO2014013019A1/en not_active Ceased
- 2013-07-18 BR BR112014032169A patent/BR112014032169A2/pt not_active IP Right Cessation
- 2013-07-18 KR KR20157004250A patent/KR20150036710A/ko not_active Withdrawn
- 2013-07-18 CA CA2875486A patent/CA2875486A1/en not_active Abandoned
- 2013-07-18 JP JP2015522098A patent/JP2015528802A/ja active Pending
- 2013-07-18 AU AU2013291964A patent/AU2013291964B2/en not_active Expired - Fee Related
- 2013-07-18 US US14/412,797 patent/US20150166664A1/en not_active Abandoned
- 2013-07-18 CN CN201380034959.0A patent/CN104394887A/zh active Pending
- 2013-07-18 SG SG11201407841YA patent/SG11201407841YA/en unknown
- 2013-07-18 EP EP13739973.9A patent/EP2874658A1/en not_active Withdrawn
- 2013-07-18 EA EA201590237A patent/EA201590237A1/ru unknown
- 2013-07-18 MX MX2015000730A patent/MX2015000730A/es unknown
- 2013-07-18 NZ NZ701974A patent/NZ701974A/en not_active IP Right Cessation
- 2013-07-18 MA MA37961A patent/MA37961A1/fr unknown
-
2014
- 2014-12-05 ZA ZA2014/08938A patent/ZA201408938B/en unknown
-
2015
- 2015-01-14 IL IL236714A patent/IL236714A0/en unknown