JP2015528312A5 - - Google Patents

Download PDF

Info

Publication number
JP2015528312A5
JP2015528312A5 JP2015532113A JP2015532113A JP2015528312A5 JP 2015528312 A5 JP2015528312 A5 JP 2015528312A5 JP 2015532113 A JP2015532113 A JP 2015532113A JP 2015532113 A JP2015532113 A JP 2015532113A JP 2015528312 A5 JP2015528312 A5 JP 2015528312A5
Authority
JP
Japan
Prior art keywords
genetically modified
modified yeast
yeast cell
phosphoenolpyruvate
dehydrogenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015532113A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015528312A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/059828 external-priority patent/WO2014043591A1/en
Publication of JP2015528312A publication Critical patent/JP2015528312A/ja
Publication of JP2015528312A5 publication Critical patent/JP2015528312A5/ja
Pending legal-status Critical Current

Links

JP2015532113A 2012-09-14 2013-09-13 低pH条件下での発酵による有機酸の生産 Pending JP2015528312A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261701293P 2012-09-14 2012-09-14
US61/701,293 2012-09-14
PCT/US2013/059828 WO2014043591A1 (en) 2012-09-14 2013-09-13 Production of organic acids by fermentation at low ph

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018089765A Division JP6879976B2 (ja) 2012-09-14 2018-05-08 低pH条件下での発酵による有機酸の生産

Publications (2)

Publication Number Publication Date
JP2015528312A JP2015528312A (ja) 2015-09-28
JP2015528312A5 true JP2015528312A5 (cg-RX-API-DMAC10.html) 2016-06-02

Family

ID=50278737

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015532113A Pending JP2015528312A (ja) 2012-09-14 2013-09-13 低pH条件下での発酵による有機酸の生産
JP2018089765A Active JP6879976B2 (ja) 2012-09-14 2018-05-08 低pH条件下での発酵による有機酸の生産
JP2020080054A Pending JP2020127417A (ja) 2012-09-14 2020-04-30 低pH条件下での発酵による有機酸の生産

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018089765A Active JP6879976B2 (ja) 2012-09-14 2018-05-08 低pH条件下での発酵による有機酸の生産
JP2020080054A Pending JP2020127417A (ja) 2012-09-14 2020-04-30 低pH条件下での発酵による有機酸の生産

Country Status (9)

Country Link
US (1) US11072807B2 (cg-RX-API-DMAC10.html)
EP (1) EP2895593B1 (cg-RX-API-DMAC10.html)
JP (3) JP2015528312A (cg-RX-API-DMAC10.html)
KR (1) KR102253532B1 (cg-RX-API-DMAC10.html)
CN (1) CN104812889B (cg-RX-API-DMAC10.html)
BR (1) BR112015005416A2 (cg-RX-API-DMAC10.html)
CA (1) CA2884266C (cg-RX-API-DMAC10.html)
MY (1) MY182946A (cg-RX-API-DMAC10.html)
WO (1) WO2014043591A1 (cg-RX-API-DMAC10.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340804B2 (en) 2007-11-20 2016-05-17 Dsm Ip Assets B.V. Dicarboxylic acid production in eukaryotes
KR102311681B1 (ko) 2015-07-28 2021-10-12 삼성전자주식회사 내산성을 갖는 효모 세포, 그를 이용하여 유기산을 생산하는 방법 및 상기 내산성 효모 세포를 생산하는 방법
WO2017151811A1 (en) * 2016-03-02 2017-09-08 Myriant Corporation Improved muconic acid production from genetically engineered microorganisms
EP3267345A1 (en) * 2016-07-06 2018-01-10 European Molecular Biology Laboratory Methods for adaptive laboratory evolution
KR20200023451A (ko) * 2017-06-30 2020-03-04 피티티 글로벌 케미칼 피씨엘 숙신산 생성이 증가된 유전자 변형 효모
CA3068459A1 (en) 2017-06-30 2019-01-03 Ptt Global Chemical Public Company Limited Microorganism with stabilized copy number of functional dna sequence and associated methods
WO2019159011A2 (en) 2018-02-16 2019-08-22 Ptt Global Chemical Public Company Limited Microorganisms and processes for lactic acid production
CN108676736B (zh) * 2018-04-20 2020-05-19 华中农业大学 一株可降解柠檬酸的毕赤酵母菌及其应用
CN112513261B (zh) * 2018-05-25 2024-07-19 丹尼斯科美国公司 富马酸还原酶过表达导致酵母中增加的发酵速率
WO2021034276A2 (en) * 2019-08-19 2021-02-25 Ptt Global Chemical Public Company Limited Yeast having improvement of lactic acid tolerance and use thereof
CN117467551A (zh) * 2022-07-29 2024-01-30 中国科学院天津工业生物技术研究所 一种高产l-苹果酸的耐酸酵母菌株及其构建方法和应用
CN119875861A (zh) * 2023-10-24 2025-04-25 中国石油化工股份有限公司 一株耐酸马克斯克鲁维酵母菌株及其在生产丁二酸中的应用
CN119162073A (zh) * 2024-11-01 2024-12-20 湖南省微生物研究院 一株柠檬酸杆菌基因工程菌株及其构建方法和应用
CN121801724A (zh) * 2026-03-09 2026-04-07 金发科技股份有限公司 一种工程化库德里亚兹毕赤酵母及其应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
EP1183385B1 (en) 1999-05-21 2006-07-19 Cargill Dow LLC Methods and materials for the synthesis of organic products
US7141410B2 (en) 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
RU2182689C1 (ru) 2001-06-14 2002-05-20 Юрий Эдуардович Зевацкий Способ и устройство для охлаждения рабочего тела и способ генерации микроволнового излучения
ATE367436T1 (de) 2002-05-30 2007-08-15 Natureworks Llc Verfahren und materialien zur produktion von d- milchsäure in hefe
JP2008545429A (ja) 2005-06-02 2008-12-18 カーギル インコーポレイテッド 遺伝子操作されたIssatchenkiaorientalis種又はその近隣種の酵母及びこの酵母を用いた発酵方法
CN101300356A (zh) * 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
CA2623751A1 (en) 2005-09-22 2007-04-05 Tate & Lyle Ingredients Americas, Inc. Improved strains for the production of organic acids
EP1975232A4 (en) 2005-10-14 2009-07-29 Toray Industries YEAST AND METHOD FOR THE PRODUCTION OF L-MILKY ACID
US20080090273A1 (en) * 2005-11-21 2008-04-17 Aaron Adriaan Winkler Malic Acid Production in Recombinant Yeast
JP5121070B2 (ja) 2005-11-23 2013-01-16 ネイチャーワークス・エル・エル・シー L−又はd−ラクタート:フェリチトクロームc酸化還元酵素遺伝子が機能しない乳酸産生酵母
DE102007019184A1 (de) * 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
US20110039327A1 (en) 2007-05-18 2011-02-17 Aaron Adriaan Winkler Organic acid production by fungal cells
WO2009013159A2 (en) 2007-07-23 2009-01-29 Dsm Ip Assets B.V. Acetyl-coa producing enzymes in yeast
US9340804B2 (en) * 2007-11-20 2016-05-17 Dsm Ip Assets B.V. Dicarboxylic acid production in eukaryotes
EP2222854A1 (en) 2007-11-20 2010-09-01 DSM IP Assets B.V. Dicarboxylic acid production in a filamentous fungus
US8735112B2 (en) 2007-11-20 2014-05-27 Dsm Ip Assets B.V. Dicarboxylic acid production in a recombinant yeast
CA2714088A1 (en) 2008-02-15 2009-08-20 Dsm Ip Assets B.V. Process for the production of a dicarboxylic acid
US9012187B2 (en) 2008-07-08 2015-04-21 Dsm Ip Assets B.V. Dicarboxylic acid production by fermentation at low pH
DE102008051727A1 (de) 2008-10-17 2010-04-22 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
US20100104771A1 (en) 2008-10-24 2010-04-29 Applied Materials, Inc. Electrode and power coupling scheme for uniform process in a large-area pecvd chamber
RU2422526C2 (ru) 2009-01-30 2011-06-27 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов (ФГУП ГосНИИгенетика) СПОСОБ ПОЛУЧЕНИЯ ЯНТАРНОЙ КИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ ДРОЖЖЕЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Yarrowia
EP2414505B1 (en) * 2009-04-02 2019-05-22 University of Florida Research Foundation, Inc. Engineering the pathway for succinate production
WO2010118932A1 (en) 2009-04-15 2010-10-21 Dsm Ip Assets B.V. Dicarboxylic acid production process
BR112012002153A2 (pt) * 2009-07-30 2015-09-15 Metabolic Explorer Sa metilglioxal sintase mutante (mgs) para a produção de material bioquímico por fermentação
PL2470667T3 (pl) 2009-08-27 2018-04-30 Dsm Ip Assets B.V. Sposób wytwarzania kwasu dikarboksylowego na drodze fermentacji
WO2011063157A2 (en) 2009-11-18 2011-05-26 Myriant Technologies Llc Organic acid production in microorganisms by combined reductive and oxidative tricarboxylic acid cycle pathways
US8945140B2 (en) * 2010-06-18 2015-02-03 Vantage Surgical Systems, Inc. Surgical procedures using instrument to boundary spacing information extracted from real-time diagnostic scan data
BR112013006883A2 (pt) 2010-09-24 2016-06-07 Dsm Ip Assets Bv processo de produção de ácido dicarboxílico
EP2495304A1 (en) * 2010-12-03 2012-09-05 DSM IP Assets B.V. Dicarboxylic acid production in a yeast cell
EP2668281A4 (en) * 2011-01-25 2015-08-26 Cargill Inc COMPOSITIONS AND METHODS OF SUCCINATE MANUFACTURE
WO2012103263A2 (en) 2011-01-25 2012-08-02 Finley Kenneth R Compositions and methods for malate and fumarate production

Similar Documents

Publication Publication Date Title
Ahn et al. Production of succinic acid by metabolically engineered microorganisms
US11821021B2 (en) Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P+) transhydrogenase enzyme
JP6191061B2 (ja) コハク酸を生産するための組換え大腸菌、及び組み換え大腸菌の使用
Su et al. The use of lactic acid-producing, malic acid-producing, or malic acid-degrading yeast strains for acidity adjustment in the wine industry
Xu et al. Fumaric acid production in Saccharomyces cerevisiae by simultaneous use of oxidative and reductive routes
Thakker et al. Metabolic engineering of carbon and redox flow in the production of small organic acids
EP2895593B1 (en) Production of organic acids by fermentation at low ph
US10190139B2 (en) Method for lactic acid production using Monascus strains modified for lactic acid production
CA2545363A1 (en) Rumen bacteria mutants and process for producing succinic acid employing the same
JP2013507145A5 (cg-RX-API-DMAC10.html)
CA2688938A1 (en) Materials and methods for efficient succinate and malate production
RU2014153354A (ru) Способ получения 2,4-дигидроксибутирата
WO2013112939A2 (en) Methods for succinate production
Lee et al. Co-expression of two heterologous lactate dehydrogenases genes in Kluyveromyces marxianus for l-lactic acid production
Ling et al. Role of the mitochondrial citrate-oxoglutarate carrier in lipid accumulation in the oleaginous fungus Mortierella alpina
Yang et al. Improvement of pyruvate production based on regulation of intracellular redox state in engineered Escherichia coli
US20160068872A1 (en) Compositions and methods for malate and fumarate production
US20130309736A1 (en) Compositions and methods for malate and fumarate production
CN105378093A (zh) 发酵方法
Zhou et al. Development of robust dominant-metabolism compromised intermediate chassis of ethanologenic Saccharomyces cerevisiae for non-ethanol biochemical production
JP2013063030A5 (cg-RX-API-DMAC10.html)
US20180371508A1 (en) Microbial production of succinate derived products