JP2015527366A - 抗原結合および多価fcガンマ受容体結合活性を有する分子 - Google Patents

抗原結合および多価fcガンマ受容体結合活性を有する分子 Download PDF

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JP2015527366A
JP2015527366A JP2015528591A JP2015528591A JP2015527366A JP 2015527366 A JP2015527366 A JP 2015527366A JP 2015528591 A JP2015528591 A JP 2015528591A JP 2015528591 A JP2015528591 A JP 2015528591A JP 2015527366 A JP2015527366 A JP 2015527366A
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オルセン,ヘンリック
ブロック,デーヴィッド
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グリックニック インコーポレイテッド
グリックニック インコーポレイテッド
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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JP2015528591A 2012-08-20 2013-08-20 抗原結合および多価fcガンマ受容体結合活性を有する分子 Pending JP2015527366A (ja)

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US201261691057P 2012-08-20 2012-08-20
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US201361785144P 2013-03-14 2013-03-14
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PCT/US2013/055800 WO2014031646A2 (en) 2012-08-20 2013-08-20 Molecules with antigen binding and polyvalent fc gamma receptor binding activity

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JP2019519527A (ja) * 2016-05-23 2019-07-11 モメンタ ファーマシューティカルズ インコーポレイテッド 操作されたFcコンストラクトに関する組成物及び方法
JP2021502360A (ja) * 2017-11-09 2021-01-28 メディミューン,エルエルシー 二重特異的融合ポリペプチド及びその使用方法
US11220531B2 (en) 2017-01-06 2022-01-11 Janssen Biotech, Inc. Engineered Fc constructs
US12071482B2 (en) 2014-05-02 2024-08-27 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered Fc constructs
US12391759B2 (en) 2016-03-02 2025-08-19 Momenta Pharmaceuticals, Inc. Methods related to engineered Fc constructs

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US12275797B2 (en) 2018-06-22 2025-04-15 Genmab Holding B.V. Anti-CD37 antibodies and anti-CD20 antibodies, compositions and methods of use thereof
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KR20210043582A (ko) * 2018-07-11 2021-04-21 모멘타 파머슈티컬스 인코포레이티드 조작된 Fc-항원 결합 도메인 작제물에 관련된 조성물 및 방법
SG11202012993SA (en) 2018-07-13 2021-02-25 Genmab As Variants of cd38 antibody and uses thereof
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US20220315661A1 (en) 2019-05-09 2022-10-06 Genmab B.V. Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
JP2023500701A (ja) 2019-11-06 2023-01-10 ジェンマブ ビー.ブイ. 抗体変種の組み合わせおよびその使用
PE20230113A1 (es) 2020-01-16 2023-01-27 Genmab As Formulaciones de anticuerpos anti-cd38 y usos de las mismas
EP4185388A1 (en) 2020-07-23 2023-05-31 Genmab B.V. A combination of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
IL301513A (en) 2020-10-02 2023-05-01 Genmab As Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
TW202328192A (zh) 2021-09-06 2023-07-16 荷蘭商珍美寶公司 能結合cd27之抗體、彼之變異體及彼等之用途
US20250084169A1 (en) 2022-01-12 2025-03-13 Biomolecular Holdings Llc Nk/monocyte engagers
IL316632A (en) 2022-05-12 2024-12-01 Genmab As Binding agents capable of binding to CD27 in combination therapy
WO2023218046A1 (en) 2022-05-12 2023-11-16 Genmab A/S Binding agents capable of binding to cd27 in combination therapy
TW202432177A (zh) 2022-10-31 2024-08-16 丹麥商珍美寶股份有限公司 Cd38抗體及其用途
KR20240156564A (ko) * 2023-04-21 2024-10-30 상트네어바이오사이언스 주식회사 두 개의 Fc 도메인을 포함하는 항원 결합 단백질 및 이의 용도
AU2024271605A1 (en) 2023-05-12 2025-11-13 BioNTech SE Antibodies capable of binding to ox40, variants thereof and uses thereof
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