JP2015527316A5 - - Google Patents
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- Publication number
- JP2015527316A5 JP2015527316A5 JP2015521033A JP2015521033A JP2015527316A5 JP 2015527316 A5 JP2015527316 A5 JP 2015527316A5 JP 2015521033 A JP2015521033 A JP 2015521033A JP 2015521033 A JP2015521033 A JP 2015521033A JP 2015527316 A5 JP2015527316 A5 JP 2015527316A5
- Authority
- JP
- Japan
- Prior art keywords
- hdac4
- group
- combination
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20125795 | 2012-07-13 | ||
| FI20125795 | 2012-07-13 | ||
| PCT/FI2013/050745 WO2014009609A1 (en) | 2012-07-13 | 2013-07-11 | Combination therapy iii |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015527316A JP2015527316A (ja) | 2015-09-17 |
| JP2015527316A5 true JP2015527316A5 (https=) | 2016-09-01 |
| JP6393682B2 JP6393682B2 (ja) | 2018-09-19 |
Family
ID=48917570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015521033A Expired - Fee Related JP6393682B2 (ja) | 2012-07-13 | 2013-07-11 | 併用療法ｉｉｉ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10166241B2 (https=) |
| EP (1) | EP2872631B1 (https=) |
| JP (1) | JP6393682B2 (https=) |
| CN (1) | CN104619845A (https=) |
| CA (1) | CA2878873C (https=) |
| DK (1) | DK2872631T3 (https=) |
| ES (1) | ES2627500T3 (https=) |
| WO (1) | WO2014009609A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106344923B (zh) * | 2016-09-23 | 2019-09-27 | 中国人民解放军第二军医大学第二附属医院 | 组蛋白去乙酰化酶-4抑制剂在制备治疗多发性骨髓瘤疾病药物中的应用 |
| US12441707B2 (en) | 2019-12-30 | 2025-10-14 | Tyra Biosciences, Inc. | Indazole compounds |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133437A (en) | 1997-02-13 | 2000-10-17 | Apoptogen, Inc. | Modulation of IAPs for the treatment of proliferative diseases |
| US7741298B2 (en) * | 1997-06-20 | 2010-06-22 | New York University | Method and compositions for inhibiting tumorigenesis |
| EP1135135A4 (en) | 1998-09-18 | 2006-08-09 | Smithkline Beecham Corp | CHK1 KINASE INHIBITORS |
| US6214986B1 (en) | 1998-10-07 | 2001-04-10 | Isis Pharmaceuticals, Inc. | Antisense modulation of bcl-x expression |
| US20030190635A1 (en) | 2002-02-20 | 2003-10-09 | Mcswiggen James A. | RNA interference mediated treatment of Alzheimer's disease using short interfering RNA |
| EP1386004A4 (en) | 2001-04-05 | 2005-02-16 | Ribozyme Pharm Inc | MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATORY PROLIFERATION AND GROWTH OF NEURITIES BY METHODS INVOLVING NUCLEIC ACID |
| US20030175950A1 (en) | 2001-05-29 | 2003-09-18 | Mcswiggen James A. | RNA interference mediated inhibition of HIV gene expression using short interfering RNA |
| US20040019001A1 (en) | 2002-02-20 | 2004-01-29 | Mcswiggen James A. | RNA interference mediated inhibition of protein typrosine phosphatase-1B (PTP-1B) gene expression using short interfering RNA |
| AU2003211576A1 (en) * | 2002-02-20 | 2003-09-09 | Sueharu Horinouchi | Histone deacetylase inhibitors and process for producing the same |
| WO2004017991A1 (en) | 2002-08-13 | 2004-03-04 | Cell Center Cologne Gmbh | Use of iap for the diagnosis and of iap-inhibitors for the treatment of hodgkin’s lymphomas |
| US20050008617A1 (en) | 2002-09-28 | 2005-01-13 | Massachusetts Institute Of Technology | Compositions and methods for delivery of short interfering RNA and short hairpin RNA |
| US20040077083A1 (en) * | 2002-10-17 | 2004-04-22 | Isis Pharmaceuticals Inc. | Antisense modulation of histone deacetylase 4 expression |
| US20040077084A1 (en) | 2002-10-17 | 2004-04-22 | Isis Pharmaceuticals Inc. | Antisense modulation of histone deacetylase 4 expression |
| AU2003295600A1 (en) | 2002-11-14 | 2004-06-15 | Dharmacon, Inc. | Functional and hyperfunctional sirna |
| CA2523517C (en) | 2003-04-25 | 2013-07-30 | Dana-Farber Cancer Institute, Inc. | Bcl2l12 polypeptide activators and inhibitors |
| US20050043266A1 (en) | 2003-07-25 | 2005-02-24 | Sumedha Jayasena | Short interfering RNA as an antiviral agent for hepatitis C |
| WO2005011598A2 (en) | 2003-07-31 | 2005-02-10 | University Of South Florida | Leukemia treatment method and composition |
| EP1653973A1 (en) | 2003-08-08 | 2006-05-10 | Novartis AG | Combinations comprising staurosporines |
| MX2007001155A (es) | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| AU2006210994A1 (en) * | 2005-02-07 | 2006-08-10 | Topotarget Uk Limited | Assays for agents with selective cytotoxicty to HDAC resistant cell lines |
| US20080021198A1 (en) | 2005-10-12 | 2008-01-24 | Yigong Shi | Modulators of protein phosphatase 2A and PP2A methyl esterase |
| US8222423B2 (en) * | 2006-02-14 | 2012-07-17 | Dana-Farber Cancer Institute, Inc. | Bifunctional histone deacetylase inhibitors |
| GB0612542D0 (en) | 2006-06-23 | 2006-08-02 | Novartis Ag | Combinations comprising staurosporines |
| AU2007333799A1 (en) * | 2006-12-15 | 2008-06-26 | Novartis Ag | Heterocycle compounds and methods of use thereof |
| US10611818B2 (en) * | 2007-09-27 | 2020-04-07 | Agilent Technologies, Inc. | MHC multimers in tuberculosis diagnostics, vaccine and therapeutics |
| EA018618B1 (ru) * | 2007-10-01 | 2013-09-30 | Ликсте Байотекнолоджи, Инк. | Ингибиторы hdac |
| EP2231596A4 (en) * | 2007-12-14 | 2012-06-06 | Univ Georgetown | INHIBITORS OF HISTONATE ACETYLASE |
| US20090274682A1 (en) | 2008-02-05 | 2009-11-05 | The Trustees Of Princeton University | Demethylation and inactivation of protein phosphatase 2a |
| CN102307475A (zh) | 2009-02-04 | 2012-01-04 | 彼帕科学公司 | 用与生长因子抑制剂组合的parp抑制剂治疗肺癌 |
-
2013
- 2013-07-11 WO PCT/FI2013/050745 patent/WO2014009609A1/en not_active Ceased
- 2013-07-11 EP EP13745446.8A patent/EP2872631B1/en not_active Not-in-force
- 2013-07-11 DK DK13745446.8T patent/DK2872631T3/en active
- 2013-07-11 CN CN201380047501.9A patent/CN104619845A/zh active Pending
- 2013-07-11 ES ES13745446.8T patent/ES2627500T3/es active Active
- 2013-07-11 US US14/414,393 patent/US10166241B2/en not_active Expired - Fee Related
- 2013-07-11 JP JP2015521033A patent/JP6393682B2/ja not_active Expired - Fee Related
- 2013-07-11 CA CA2878873A patent/CA2878873C/en not_active Expired - Fee Related
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