JP2015524807A5 - - Google Patents

Download PDF

Info

Publication number
JP2015524807A5
JP2015524807A5 JP2015524402A JP2015524402A JP2015524807A5 JP 2015524807 A5 JP2015524807 A5 JP 2015524807A5 JP 2015524402 A JP2015524402 A JP 2015524402A JP 2015524402 A JP2015524402 A JP 2015524402A JP 2015524807 A5 JP2015524807 A5 JP 2015524807A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
pharmaceutically acceptable
compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015524402A
Other languages
English (en)
Japanese (ja)
Other versions
JP6391071B2 (ja
JP2015524807A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/051745 external-priority patent/WO2014018570A1/en
Publication of JP2015524807A publication Critical patent/JP2015524807A/ja
Publication of JP2015524807A5 publication Critical patent/JP2015524807A5/ja
Application granted granted Critical
Publication of JP6391071B2 publication Critical patent/JP6391071B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015524402A 2012-07-25 2013-07-23 シスタチオニン−γ−リアーゼ(CSE)阻害剤 Expired - Fee Related JP6391071B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261675754P 2012-07-25 2012-07-25
US61/675,754 2012-07-25
PCT/US2013/051745 WO2014018570A1 (en) 2012-07-25 2013-07-23 Cystathionine-υ-lyase (cse) inhibitors

Publications (3)

Publication Number Publication Date
JP2015524807A JP2015524807A (ja) 2015-08-27
JP2015524807A5 true JP2015524807A5 (enExample) 2016-08-18
JP6391071B2 JP6391071B2 (ja) 2018-09-19

Family

ID=49997791

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015524402A Expired - Fee Related JP6391071B2 (ja) 2012-07-25 2013-07-23 シスタチオニン−γ−リアーゼ(CSE)阻害剤

Country Status (13)

Country Link
US (2) US9725426B2 (enExample)
EP (1) EP2877457B1 (enExample)
JP (1) JP6391071B2 (enExample)
KR (1) KR20150041635A (enExample)
CN (1) CN104662007B (enExample)
AR (1) AR091857A1 (enExample)
AU (2) AU2013293090A1 (enExample)
CA (1) CA2879879C (enExample)
HK (1) HK1210614A1 (enExample)
IN (1) IN2015DN01161A (enExample)
RU (1) RU2661879C2 (enExample)
TW (1) TWI684583B (enExample)
WO (1) WO2014018570A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
AR091857A1 (es) 2012-07-25 2015-03-04 Sova Pharmaceuticals Inc INHIBIDORES DE CISTATIONIN-g-LIASA (CSE)
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP6394690B2 (ja) * 2014-02-28 2018-09-26 日本ゼオン株式会社 1,1−ジ置換ヒドラジン化合物の製造方法
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
PL3166599T3 (pl) * 2014-07-09 2025-09-22 Sun Pharmaceutical Industries Ltd Postać dawkowania w formie kapsułek zawierających bursztynian metoprololu
US9617230B2 (en) * 2014-12-22 2017-04-11 Farmington Pharma Development Creatine prodrugs, compositions and methods of use thereof
US11021501B2 (en) 2015-03-30 2021-06-01 Farmington Pharma Development Creatine phosphate analog prodrugs, compositions and methods of use thereof
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR102678696B1 (ko) 2017-12-01 2024-06-27 울트라제닉스 파마수티컬 인코포레이티드 크레아틴 전구약물, 조성물과 이의 사용 방법
CN114174288A (zh) * 2019-06-07 2022-03-11 安吉奥斯医药品有限公司 用氨基乙酰丙酸合酶2(alas2)调节剂治疗的方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD13769A (enExample) *
DE207626C (enExample) * 1900-01-01
DE13769C (de) W. H. MC. NARY in Brooklyn (Staat New-York, V. St. A.); Vertreter : F. E. THODE & KNOOP in Dresden, Augustusstrafse 3 II Neuerungen an flachen Kettenstühlen
NL6402073A (enExample) * 1963-03-05 1964-09-07
US4229447A (en) 1979-06-04 1980-10-21 American Home Products Corporation Intraoral methods of using benzodiazepines
DD207626A3 (de) * 1981-12-17 1984-03-07 Manfred Just Verfahren zur herstellung des 3-amino-5-hydrazino-1,2,4-triazols und dessen derivaten
US4476116A (en) 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US5116817A (en) 1982-12-10 1992-05-26 Syntex (U.S.A.) Inc. LHRH preparations for intranasal administration
US4596795A (en) 1984-04-25 1986-06-24 The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
US4610717A (en) * 1985-11-26 1986-09-09 Shell Oil Company Certain 5-(R-oxy)-1-phenyl or (3-(trifluoromethyl)phenyl)triazoles, useful for controlling undesired plant growth
DE3684446D1 (de) 1985-12-28 1992-04-23 Sumitomo Pharma Arzneimittel mit verzoegerter stossweiser freisetzung.
US4755386A (en) 1986-01-22 1988-07-05 Schering Corporation Buccal formulation
US5739136A (en) 1989-10-17 1998-04-14 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering medicaments
US5017381A (en) 1990-05-02 1991-05-21 Alza Corporation Multi-unit pulsatile delivery system
US5229135A (en) 1991-11-22 1993-07-20 Prographarm Laboratories Sustained release diltiazem formulation
US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US5840329A (en) 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
YU66101A (sh) * 1999-03-15 2004-07-15 Axys Pharmaceuticals Inc. Nova jedinjenja i kompozicije kao inhibitori proteaze
US6960563B2 (en) 2001-08-31 2005-11-01 Morton Grove Pharmaceuticals, Inc. Spontaneous emulsions containing cyclosporine
US20070232586A1 (en) * 2004-04-21 2007-10-04 Kazuyuki Ohmoto Hydrazino-Substituted Heterocyclic Nitrile Compounds and Use Thereof
AR091857A1 (es) 2012-07-25 2015-03-04 Sova Pharmaceuticals Inc INHIBIDORES DE CISTATIONIN-g-LIASA (CSE)

Similar Documents

Publication Publication Date Title
JP2015524807A5 (enExample)
RU2015105700A (ru) ИНГИБИТОРЫ ЦИСТАТИОНИН-γ-ЛИАЗЫ (CSE)
RU2015105893A (ru) Ингибиторы цистатионин-г-лиазы (cse)
US10328072B2 (en) Treatment of lung cancer using hedgehog pathway inhibitors
US20210077500A1 (en) Pikfyve inhibitors for cancer therapy
BR112021008516A2 (pt) Inibidores de quinase 7 dependente de ciclina (cdk 7)
US10583129B2 (en) Use of EP4 receptor antagonists for the treatment of NASH-associated liver cancer
JP2017526716A5 (enExample)
JP2016531861A5 (enExample)
BRPI0710682B1 (pt) Combinação farmacêutica consistente de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol e paracetamol
JP2013518882A5 (enExample)
JP2017522352A5 (enExample)
JP2017141277A (ja) 痛み治療用の医薬配合物
WO2016040527A1 (en) Metabolism probes for therapy and diagnosis
JP2013518036A5 (enExample)
WO2015008229A1 (en) Autotaxin inhibitors
JP2009040767A5 (enExample)
Turek et al. New perspectives for antihypertensive sartans as components of co-crystals and co-amorphous solids with improved properties and multipurpose activity
JP2018538241A5 (enExample)
JP2017525777A5 (enExample)
JP2018515507A5 (enExample)
CN104640538B (zh) 包含ndga 衍生物和索拉非尼的组合物以及其在治疗癌症中的用途
JP2018504391A5 (enExample)
WO2015162558A1 (en) Autotaxin inhibitors
US20190365742A1 (en) Azole treatment regimen with reduced hepatotoxicity