JP2015524420A5 - - Google Patents

Info

Publication number

JP2015524420A5

JP2015524420A5 JP2015523536A JP2015523536A JP2015524420A5 JP 2015524420 A5 JP2015524420 A5 JP 2015524420A5 JP 2015523536 A JP2015523536 A JP 2015523536A JP 2015523536 A JP2015523536 A JP 2015523536A JP 2015524420 A5 JP2015524420 A5 JP 2015524420A5

Authority

JP

Japan

Prior art keywords

protein

hpv type

seq

terminal

hpv

Prior art date

2013-07-23

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 102000004169 proteins and genes Human genes 0.000 claims 60
• 108090000623 proteins and genes Proteins 0.000 claims 60
• 102000037865 fusion proteins Human genes 0.000 claims 35
• 108020001507 fusion proteins Proteins 0.000 claims 35
• 108090000765 processed proteins & peptides Proteins 0.000 claims 32
• 210000004899 c-terminal region Anatomy 0.000 claims 29
• 229920001184 polypeptide Polymers 0.000 claims 29
• 102000004196 processed proteins & peptides Human genes 0.000 claims 29
• 239000012634 fragment Substances 0.000 claims 26
• 239000000427 antigen Substances 0.000 claims 19
• 102000036639 antigens Human genes 0.000 claims 19
• 108091007433 antigens Proteins 0.000 claims 19
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 14
• 230000028993 immune response Effects 0.000 claims 12
• 230000001575 pathological effect Effects 0.000 claims 12
• 230000002265 prevention Effects 0.000 claims 11
• 241000341655 Human papillomavirus type 16 Species 0.000 claims 9
• 238000011282 treatment Methods 0.000 claims 9
• 210000001744 T-lymphocyte Anatomy 0.000 claims 8
• 230000001939 inductive effect Effects 0.000 claims 8
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
• 208000015181 infectious disease Diseases 0.000 claims 5
• 244000052769 pathogen Species 0.000 claims 5
• 230000001717 pathogenic effect Effects 0.000 claims 5
• 231100000588 tumorigenic Toxicity 0.000 claims 5
• 230000000381 tumorigenic effect Effects 0.000 claims 5
• 230000001024 immunotherapeutic effect Effects 0.000 claims 4
• 239000003814 drug Substances 0.000 claims 3
• 108091033319 polynucleotide Proteins 0.000 claims 3
• 239000002157 polynucleotide Substances 0.000 claims 3
• 102000040430 polynucleotide Human genes 0.000 claims 3
• 241000588832 Bordetella pertussis Species 0.000 claims 2
• 241000588807 Bordetella Species 0.000 claims 1
• 108091026890 Coding region Proteins 0.000 claims 1
• 241000588724 Escherichia coli Species 0.000 claims 1
• 239000002671 adjuvant Substances 0.000 claims 1
• 238000004113 cell culture Methods 0.000 claims 1
• 101150096136 cyaC gene Proteins 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 239000002773 nucleotide Substances 0.000 claims 1
• 125000003729 nucleotide group Chemical group 0.000 claims 1
• 239000013612 plasmid Substances 0.000 claims 1
• 238000011321 prophylaxis Methods 0.000 claims 1