JP2015518736A5 - - Google Patents
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- Publication number
- JP2015518736A5 JP2015518736A5 JP2015516270A JP2015516270A JP2015518736A5 JP 2015518736 A5 JP2015518736 A5 JP 2015518736A5 JP 2015516270 A JP2015516270 A JP 2015516270A JP 2015516270 A JP2015516270 A JP 2015516270A JP 2015518736 A5 JP2015518736 A5 JP 2015518736A5
- Authority
- JP
- Japan
- Prior art keywords
- bacterium
- nucleic acid
- acid encoding
- diol
- glycerol dehydratase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000894006 Bacteria Species 0.000 claims 17
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims 12
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 9
- 108010025885 Glycerol dehydratase Proteins 0.000 claims 9
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 108010065027 Propanediol Dehydratase Proteins 0.000 claims 8
- 150000002009 diols Chemical class 0.000 claims 8
- 230000035772 mutation Effects 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 230000007420 reactivation Effects 0.000 claims 5
- OWBTYPJTUOEWEK-QWWZWVQMSA-N (R,R)-butane-2,3-diol Chemical compound C[C@@H](O)[C@@H](C)O OWBTYPJTUOEWEK-QWWZWVQMSA-N 0.000 claims 4
- 101710088194 Dehydrogenase Proteins 0.000 claims 4
- 101710168863 Diacetyl reductase [(S)-acetoin forming] Proteins 0.000 claims 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- 241001656809 Clostridium autoethanogenum Species 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 235000016709 nutrition Nutrition 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 1
- 241000588748 Klebsiella Species 0.000 claims 1
- 101000933577 Klebsiella pneumoniae Diacetyl reductase [(S)-acetoin forming] Proteins 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261657292P | 2012-06-08 | 2012-06-08 | |
| US61/657,292 | 2012-06-08 | ||
| PCT/US2013/044865 WO2013185123A1 (en) | 2012-06-08 | 2013-06-09 | Recombinant microorganisms and uses therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518736A JP2015518736A (ja) | 2015-07-06 |
| JP2015518736A5 true JP2015518736A5 (https=) | 2016-08-04 |
| JP6381525B2 JP6381525B2 (ja) | 2018-08-29 |
Family
ID=49712722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015516270A Active JP6381525B2 (ja) | 2012-06-08 | 2013-06-09 | 組換え微生物およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9890384B2 (https=) |
| EP (1) | EP2859089B1 (https=) |
| JP (1) | JP6381525B2 (https=) |
| KR (1) | KR102079275B1 (https=) |
| CN (2) | CN113186144A (https=) |
| IN (1) | IN2014DN10508A (https=) |
| WO (1) | WO2013185123A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130323820A1 (en) | 2012-06-01 | 2013-12-05 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| IN2015DN01365A (https=) | 2012-08-28 | 2015-07-03 | Lanzatech New Zealand Ltd | |
| DK3047028T5 (da) | 2013-09-22 | 2024-10-14 | Lanzatech Nz Inc | Fermenteringsfremgangsmåde |
| KR101577502B1 (ko) * | 2013-12-16 | 2015-12-14 | 지에스칼텍스 주식회사 | Ｄ（－）２，３－부탄디올의 생성능이 증강된 재조합 미생물 및 이를 이용한 ｄ（－）２，３－부탄디올의 생산 방법 |
| CA2936251C (en) | 2014-01-28 | 2017-11-07 | Lanzatech New Zealand Limited | Method of producing a recombinant microorganism |
| KR101743021B1 (ko) | 2014-05-08 | 2017-06-02 | 한국생명공학연구원 | 재조합 미생물을 이용한 l형 2,3-부탄디올의 제조방법 |
| US10113194B2 (en) | 2014-10-22 | 2018-10-30 | Lanzatech New Zealand Limited | Gas testing unit and method |
| FI3209786T3 (fi) | 2014-10-22 | 2023-06-13 | Lanzatech Nz Inc | Monivaiheisia bioreaktoriprosesseja |
| DK3230459T3 (da) | 2014-12-08 | 2020-12-07 | Lanzatech New Zealand Ltd | Rekombinante mikroorganismer med øget strømning gennem en fermenteringsbane |
| WO2016138050A1 (en) | 2015-02-23 | 2016-09-01 | Lanzatech New Zealand Limited | Recombinant acetogenic bacterium for the conversion of methane to products |
| CA3151149C (en) | 2015-10-13 | 2024-03-26 | Lanzatech Nz, Inc. | Genetically engineered bacterium comprising energy-generating fermentation pathway |
| CN108431208A (zh) | 2015-12-03 | 2018-08-21 | 朗泽科技新西兰有限公司 | 增补精氨酸以改善气体发酵产乙酸菌的效率 |
| US10358661B2 (en) | 2015-12-28 | 2019-07-23 | Lanzatech New Zealand Limited | Microorganism with modified hydrogenase activity |
| PT3411489T (pt) | 2016-02-01 | 2023-08-07 | Lanzatech Nz Inc | Processo de fermentação e eletrólise integrado |
| EP3420089B1 (en) * | 2016-02-26 | 2021-12-29 | LanzaTech NZ, Inc. | Crispr/cas systems for c-1 fixing bacteria |
| WO2017200884A1 (en) | 2016-05-14 | 2017-11-23 | Lanzatech, Inc. | Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods |
| CN111051517B (zh) | 2017-09-08 | 2023-10-27 | 朗泽科技有限公司 | 用于使用富氢气的含有c1的底物生产代谢物的方法和系统 |
| US11555209B2 (en) * | 2017-12-19 | 2023-01-17 | Lanzatech, Inc. | Microorganisms and methods for the biological production of ethylene glycol |
| CN111683731B (zh) | 2018-02-12 | 2022-09-02 | 朗泽科技有限公司 | 用于提高碳转化效率的工艺 |
| US11053517B2 (en) | 2018-04-20 | 2021-07-06 | Lanzatech, Inc. | Intermittent electrolysis streams |
| CN112955558A (zh) | 2018-11-19 | 2021-06-11 | 朗泽科技有限公司 | 发酵和气化的集成 |
| BR112021014626A2 (pt) | 2019-01-29 | 2021-10-05 | Lanzatech, Inc. | Método para produzir gás liquefeito de petróleo |
| CN112969795A (zh) | 2019-02-08 | 2021-06-15 | 朗泽科技有限公司 | 用于回收沸点接近的产物的方法 |
| WO2020188033A1 (en) | 2019-03-20 | 2020-09-24 | Global Bioenergies | Improved means and methods for producing isobutene from acetyl-coa |
| WO2021006995A1 (en) | 2019-07-11 | 2021-01-14 | Lanzatech, Inc. | Methods for optimizing gas utilization |
| US11932818B2 (en) | 2020-03-16 | 2024-03-19 | Lanzatech, Inc. | Tail gas of gas fermentation to dry gasification feedstock |
| JP2023518045A (ja) | 2020-03-18 | 2023-04-27 | ランザテク，インコーポレイテッド | ガス基質からの２－フェニルエタノールの発酵産生 |
| KR20220159450A (ko) | 2020-04-29 | 2022-12-02 | 란자테크, 인크. | 가스성 기질로부터의 β-케토아디페이트의 발효 제조 |
| US11760989B2 (en) | 2020-06-06 | 2023-09-19 | Lanzatech, Inc. | Microorganism with knock-in at acetolactate decarboxylase gene locus |
| US11788092B2 (en) | 2021-02-08 | 2023-10-17 | Lanzatech, Inc. | Recombinant microorganisms and uses therefor |
| JP2024513395A (ja) | 2021-04-09 | 2024-03-25 | ランザテク，インコーポレイテッド | 供給原料を提供するためのプロセス及び装置 |
| US12241105B2 (en) | 2021-07-20 | 2025-03-04 | Lanzatech, Inc. | Recombinant microorganisms and uses therefor |
| TW202307202A (zh) | 2021-08-06 | 2023-02-16 | 美商朗澤科技有限公司 | 用於改良乙二醇之生物產生的微生物及方法 |
| US12091648B2 (en) | 2021-11-03 | 2024-09-17 | Lanzatech, Inc. | System and method for generating bubbles in a vessel |
| US12280331B2 (en) | 2022-04-29 | 2025-04-22 | Lanzatech, Inc. | Low residence time gas separator |
| US12077800B2 (en) | 2022-06-16 | 2024-09-03 | Lanzatech, Inc. | Liquid distributor system and process of liquid distribution |
| AU2023286621A1 (en) | 2022-06-21 | 2025-01-09 | Lanzatech, Inc. | Microorganisms and methods for the continuous co-production of tandem repeat proteins and chemical products from c1-substrates |
| CN119403929A (zh) | 2022-06-21 | 2025-02-07 | 朗泽科技有限公司 | 用于由c1底物连续共产生高价值专用蛋白和化学产物的微生物和方法 |
| US12129503B2 (en) | 2022-08-10 | 2024-10-29 | Lanzatech, Inc. | Carbon sequestration in soils with production of chemical products |
| KR102951928B1 (ko) * | 2022-08-16 | 2026-04-14 | 한국과학기술원 | 일산화탄소 이용능이 증대된 미생물 및 이를 이용한 2,3-bdo 생산 |
| WO2024253882A1 (en) | 2023-06-05 | 2024-12-12 | Lanzatech, Inc. | Integrated gas fermentation |
| US12359224B2 (en) | 2023-06-05 | 2025-07-15 | Lanzatech, Inc. | Integrated gas fermentation and carbon black processes |
| CN121368428A (zh) | 2023-07-14 | 2026-01-20 | 揖斐电株式会社 | 组合物及化妆品的原料组合物 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| US5593886A (en) | 1992-10-30 | 1997-01-14 | Gaddy; James L. | Clostridium stain which produces acetic acid from waste gases |
| UA72220C2 (uk) | 1998-09-08 | 2005-02-15 | Байоенджініерінг Рісорсиз, Інк. | Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання |
| WO2002008438A2 (en) | 2000-07-25 | 2002-01-31 | Bioengineering Resources, Inc. | Methods for increasing the production of ethanol from microbial fermentation |
| US8206970B2 (en) | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| ZA200807719B (en) * | 2006-05-02 | 2009-12-30 | Du Pont | Fermentive production of four carbon alcohols |
| US7704723B2 (en) | 2006-08-31 | 2010-04-27 | The Board Of Regents For Oklahoma State University | Isolation and characterization of novel clostridial species |
| US20080274522A1 (en) * | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of 2-butanone |
| FR2916000B1 (fr) * | 2007-05-07 | 2013-07-05 | Lallemand Sas | Moyens pour reduire l'accumulation d'acetoine dans des milieux de fermentation alcoolique |
| JP5600296B2 (ja) | 2007-11-13 | 2014-10-01 | ランザテク・ニュージーランド・リミテッド | 新規細菌及びその使用法 |
| US8372612B2 (en) * | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| CN102317463B (zh) * | 2008-06-09 | 2014-12-03 | 蓝瑟科技纽西兰有限公司 | 厌氧微生物发酵生产丁二醇 |
| AU2009296227A1 (en) * | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| WO2010057022A1 (en) * | 2008-11-14 | 2010-05-20 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| EP2373781A4 (en) * | 2008-12-16 | 2012-10-10 | Genomatica Inc | MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS |
| US8039239B2 (en) * | 2008-12-16 | 2011-10-18 | Coskata, Inc. | Recombinant microorganisms having modified production of alcohols and acids |
| EP2483401B1 (en) * | 2009-09-29 | 2017-06-21 | Butamax (TM) Advanced Biofuels LLC | Improved yeast production host cells |
| US8143037B2 (en) | 2010-03-19 | 2012-03-27 | Coskata, Inc. | Ethanologenic Clostridium species, Clostridium coskatii |
| WO2012034023A2 (en) * | 2010-09-10 | 2012-03-15 | University Of Delaware | Recombinant clostridia that fix co2 and co and uses thereof |
| US20110236941A1 (en) * | 2010-10-22 | 2011-09-29 | Lanzatech New Zealand Limited | Recombinant microorganism and methods of production thereof |
| BR112013021524A2 (pt) | 2011-02-25 | 2017-06-13 | Lanzatech New Zealand Ltd | micro-organismos recombinantes e usos dos mesmos |
| WO2014092562A1 (en) * | 2012-12-11 | 2014-06-19 | Photanol B.V. | Synthesis of acetoin, 2,3-butanediol and 2-butanol by cyanobacteria by heterologous expression of a catabolic pathway |
-
2013
- 2013-06-09 CN CN202110477268.4A patent/CN113186144A/zh active Pending
- 2013-06-09 JP JP2015516270A patent/JP6381525B2/ja active Active
- 2013-06-09 EP EP13800454.4A patent/EP2859089B1/en active Active
- 2013-06-09 WO PCT/US2013/044865 patent/WO2013185123A1/en not_active Ceased
- 2013-06-09 CN CN201380042293.3A patent/CN104919037A/zh active Pending
- 2013-06-09 KR KR1020147036648A patent/KR102079275B1/ko active Active
- 2013-06-10 US US13/914,234 patent/US9890384B2/en not_active Expired - Fee Related
-
2014
- 2014-12-09 IN IN10508DEN2014 patent/IN2014DN10508A/en unknown
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