JP2015517976A5 - - Google Patents
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- JP2015517976A5 JP2015517976A5 JP2014557773A JP2014557773A JP2015517976A5 JP 2015517976 A5 JP2015517976 A5 JP 2015517976A5 JP 2014557773 A JP2014557773 A JP 2014557773A JP 2014557773 A JP2014557773 A JP 2014557773A JP 2015517976 A5 JP2015517976 A5 JP 2015517976A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- ring
- attached
- carbon atom
- heteroatoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261600036P | 2012-02-17 | 2012-02-17 | |
| US61/600,036 | 2012-02-17 | ||
| PCT/US2013/026173 WO2013123215A2 (en) | 2012-02-17 | 2013-02-14 | Antiviral drugs for treatment of arenavirus infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015517976A JP2015517976A (ja) | 2015-06-25 |
| JP2015517976A5 true JP2015517976A5 (enExample) | 2016-04-07 |
| JP6200903B2 JP6200903B2 (ja) | 2017-09-20 |
Family
ID=48984889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014557773A Expired - Fee Related JP6200903B2 (ja) | 2012-02-17 | 2013-02-14 | アレナウイルス感染症の治療のための抗ウイルス薬 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9498470B2 (enExample) |
| EP (1) | EP2814486B8 (enExample) |
| JP (1) | JP6200903B2 (enExample) |
| KR (1) | KR101893632B1 (enExample) |
| CN (3) | CN110776453A (enExample) |
| AP (1) | AP3675A (enExample) |
| AU (2) | AU2013221475B2 (enExample) |
| BR (1) | BR112014020345B1 (enExample) |
| CA (1) | CA2864484C (enExample) |
| IL (2) | IL234091A (enExample) |
| MX (1) | MX359989B (enExample) |
| SG (1) | SG11201404898RA (enExample) |
| WO (1) | WO2013123215A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101663864B1 (ko) * | 2013-04-19 | 2016-10-07 | 영남대학교 산학협력단 | 아미도피리딘올 유도체 또는 이의 약제학적 허용가능한 염을 유효성분으로 함유하는 염증성 장질환의 예방 또는 치료용 약학조성물 |
| IL305843B2 (en) * | 2015-07-20 | 2025-01-01 | Genzyme Corp | CSF-1R receptor antibodies |
| US11352328B2 (en) | 2016-07-12 | 2022-06-07 | Arisan Therapeutics Inc. | Heterocyclic compounds for the treatment of arenavirus |
| WO2018049152A1 (en) | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyrimidine derivatives as hpk1 modulators and uses thereof for the treatment of cancer |
| US10280164B2 (en) | 2016-09-09 | 2019-05-07 | Incyte Corporation | Pyrazolopyridone compounds and uses thereof |
| EP3510032B1 (en) | 2016-09-09 | 2022-07-06 | Incyte Corporation | Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer |
| WO2018049214A1 (en) | 2016-09-09 | 2018-03-15 | Incyte Corporation | Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer |
| WO2018152220A1 (en) | 2017-02-15 | 2018-08-23 | Incyte Corporation | Pyrazolopyridine compounds and uses thereof |
| WO2019051199A1 (en) | 2017-09-08 | 2019-03-14 | Incyte Corporation | 6-CYANO-INDAZOLE COMPOUNDS AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) MODULATORS |
| US10745388B2 (en) | 2018-02-20 | 2020-08-18 | Incyte Corporation | Indazole compounds and uses thereof |
| KR20200133747A (ko) | 2018-02-20 | 2020-11-30 | 인사이트 코포레이션 | 암을 치료하기 위한 hpk1 억제제로서의 n-(페닐)-2-(페닐)피리미딘-4-카복스아미드 유도체 및 관련 화합물 |
| WO2019164847A1 (en) | 2018-02-20 | 2019-08-29 | Incyte Corporation | Indazole compounds and uses thereof |
| US11299473B2 (en) | 2018-04-13 | 2022-04-12 | Incyte Corporation | Benzimidazole and indole compounds and uses thereof |
| US10899755B2 (en) | 2018-08-08 | 2021-01-26 | Incyte Corporation | Benzothiazole compounds and uses thereof |
| EP3856348B1 (en) | 2018-09-25 | 2024-01-03 | Incyte Corporation | Pyrazolo[4,3-d]pyrimidine compounds as alk2 and/or fgfr modulators |
| US11066404B2 (en) | 2018-10-11 | 2021-07-20 | Incyte Corporation | Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors |
| US12419865B2 (en) | 2018-12-06 | 2025-09-23 | Arisan Therapeutics Inc. | Compounds for the treatment of arenavirus infection |
| AR117228A1 (es) * | 2018-12-06 | 2021-07-21 | Arisan Therapeutics | DERIVADOS DE PIRAZOLO[1,2-a]PIRIDINA, 1H-BENZO[d][1,2,3]TRIAZOL, IMIDAZOPIRIMIDINA Y BENCIMIDAZOL PARA USAR EN EL TRATAMIENTO DE LA INFECCIÓN POR ARENAVIRUS |
| US11384083B2 (en) | 2019-02-15 | 2022-07-12 | Incyte Corporation | Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors |
| WO2020180959A1 (en) | 2019-03-05 | 2020-09-10 | Incyte Corporation | Pyrazolyl pyrimidinylamine compounds as cdk2 inhibitors |
| WO2020205560A1 (en) | 2019-03-29 | 2020-10-08 | Incyte Corporation | Sulfonylamide compounds as cdk2 inhibitors |
| WO2020223558A1 (en) | 2019-05-01 | 2020-11-05 | Incyte Corporation | Tricyclic amine compounds as cdk2 inhibitors |
| WO2020223469A1 (en) | 2019-05-01 | 2020-11-05 | Incyte Corporation | N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer |
| JP2022543155A (ja) | 2019-08-06 | 2022-10-07 | インサイト・コーポレイション | Ｈｐｋ１阻害剤の固体形態 |
| AU2020328025A1 (en) | 2019-08-14 | 2022-03-03 | Incyte Corporation | Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors |
| JOP20220087A1 (ar) | 2019-10-11 | 2023-01-30 | Incyte Corp | أمينات ثنائية الحلقة كمثبطات لـ cdk2 |
| CN113214161A (zh) * | 2021-02-05 | 2021-08-06 | 中国人民解放军军事科学院军事医学研究院军事认知与脑科学研究所 | 一种具有抗拉沙病毒活性的化合物及其制备方法和应用 |
| CN113234022A (zh) * | 2021-02-05 | 2021-08-10 | 中国人民解放军军事科学院军事医学研究院军事认知与脑科学研究所 | 一种苯并咪唑类衍生物及其合成方法和应用 |
| US11981671B2 (en) | 2021-06-21 | 2024-05-14 | Incyte Corporation | Bicyclic pyrazolyl amines as CDK2 inhibitors |
| WO2023009618A1 (en) * | 2021-07-28 | 2023-02-02 | Epirium Bio, Inc. | Bicyclic pgdh inhibitors and methods of making and using |
| US11976073B2 (en) | 2021-12-10 | 2024-05-07 | Incyte Corporation | Bicyclic amines as CDK2 inhibitors |
| CN116217490B (zh) * | 2023-02-03 | 2025-09-26 | 中国人民解放军军事科学院军事医学研究院 | 一种苯并咪唑类化合物及其制备方法和应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| JPS63157157A (ja) * | 1986-12-22 | 1988-06-30 | Canon Inc | 電子写真感光体 |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
| DE3928177A1 (de) * | 1989-04-08 | 1991-02-28 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| JPH0446352A (ja) * | 1990-06-14 | 1992-02-17 | Minolta Camera Co Ltd | 感光体 |
| US5554630A (en) * | 1993-03-24 | 1996-09-10 | Neurosearch A/S | Benzimidazole compounds |
| AU675484B2 (en) * | 1993-03-24 | 1997-02-06 | Neurosearch A/S | Benzimidazole compounds, their use and preparation |
| AU7275894A (en) * | 1993-08-04 | 1995-02-28 | Yamanouchi Pharmaceutical Co., Ltd. | Imidazolylalkylamine derivative and pharmaceutical composition thereof |
| UA75055C2 (uk) * | 1999-11-30 | 2006-03-15 | Пфайзер Продактс Інк. | Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі |
| DK1246808T3 (da) * | 2000-01-14 | 2011-12-05 | Bayer Pharma AG | 1,2-diarylbenzimidazoler til behandling af sygdomme, som er associeret med en mikroglia-aktivering |
| ATE402164T1 (de) * | 2001-04-26 | 2008-08-15 | Eisai R&D Man Co Ltd | Stickstoffhaltige verbindung mit kondensiertem ring und pyrazolylgruppe als substituent und medizinische zusammensetzung davon |
| FR2851248B1 (fr) * | 2003-02-18 | 2005-04-08 | Aventis Pharma Sa | Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation |
| EP1720862A1 (en) * | 2004-02-03 | 2006-11-15 | Eli Lilly And Company | Kinase inhibitors |
| DE102005012875B4 (de) * | 2005-03-19 | 2006-11-16 | Sanofi-Aventis Deutschland Gmbh | Verwendung von Amino substituierten 8-N-Benzimidazolen |
| US7872037B2 (en) * | 2006-03-02 | 2011-01-18 | Siga Technologies, Inc. | Antiviral drugs for treatment of arenavirus infection |
| US7977365B2 (en) * | 2006-03-02 | 2011-07-12 | Siga Technologies, Inc. | Antiviral drugs for treatment of arenavirus infection |
| EP2120952A4 (en) | 2007-01-15 | 2011-09-21 | Us Of America As Represented By The Secretary Of The Army On Behalf Of The U S Army Res Inst Of Infe | ANTIVIRAL COMPOUNDS AND METHODS OF USE |
| JP5393679B2 (ja) * | 2007-08-27 | 2014-01-22 | シガ・テクノロジーズ・インコーポレーテッド | アレナウイルス感染症を治療するための抗ウイルス薬 |
| WO2010030360A1 (en) * | 2008-09-11 | 2010-03-18 | Arena Pharmaceuticals, Inc. | 3H-IMIDAZO[4,5-b]PYRIDIN-5-OL DERIVATIVES USEFUL IN THE TREATMENT OF GPR81 RECEPTOR DISORDERS |
| SG172229A1 (en) * | 2008-12-18 | 2011-07-28 | Hoffmann La Roche | Thiazolyl-benzimidazoles |
| WO2011063293A1 (en) * | 2009-11-20 | 2011-05-26 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antihelminth agents |
-
2013
- 2013-02-14 AP AP2014007925A patent/AP3675A/xx active
- 2013-02-14 KR KR1020147025954A patent/KR101893632B1/ko not_active Expired - Fee Related
- 2013-02-14 CN CN201910977868.XA patent/CN110776453A/zh active Pending
- 2013-02-14 BR BR112014020345-8A patent/BR112014020345B1/pt not_active IP Right Cessation
- 2013-02-14 US US14/379,028 patent/US9498470B2/en active Active
- 2013-02-14 MX MX2014009931A patent/MX359989B/es active IP Right Grant
- 2013-02-14 AU AU2013221475A patent/AU2013221475B2/en not_active Ceased
- 2013-02-14 CN CN201380019936.2A patent/CN104507473A/zh active Pending
- 2013-02-14 SG SG11201404898RA patent/SG11201404898RA/en unknown
- 2013-02-14 CN CN201910977855.2A patent/CN110698408B/zh not_active Expired - Fee Related
- 2013-02-14 EP EP13749809.3A patent/EP2814486B8/en active Active
- 2013-02-14 WO PCT/US2013/026173 patent/WO2013123215A2/en not_active Ceased
- 2013-02-14 CA CA2864484A patent/CA2864484C/en active Active
- 2013-02-14 JP JP2014557773A patent/JP6200903B2/ja not_active Expired - Fee Related
-
2014
- 2014-08-13 IL IL234091A patent/IL234091A/en active IP Right Grant
-
2016
- 2016-11-16 US US15/353,351 patent/US10000486B2/en active Active
-
2017
- 2017-01-18 AU AU2017200346A patent/AU2017200346B2/en not_active Ceased
- 2017-03-22 IL IL251327A patent/IL251327B/en active IP Right Grant
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