JP2015517677A - 有益物質中の粒子の検出のためのシステムおよび方法 - Google Patents

有益物質中の粒子の検出のためのシステムおよび方法 Download PDF

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Publication number
JP2015517677A
JP2015517677A JP2015514197A JP2015514197A JP2015517677A JP 2015517677 A JP2015517677 A JP 2015517677A JP 2015514197 A JP2015514197 A JP 2015514197A JP 2015514197 A JP2015514197 A JP 2015514197A JP 2015517677 A JP2015517677 A JP 2015517677A
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image
beneficial agent
liquid beneficial
liquid
particles
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JP2015514197A
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Japanese (ja)
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マタヨシ，エドモンド
ワン，ジエ
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AbbVie Inc
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AbbVie Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9018—Dirt detection in containers
    • G01N21/9027—Dirt detection in containers in containers after filling
    • G01N2015/0693—

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2015514197A 2012-05-24 2013-05-23 有益物質中の粒子の検出のためのシステムおよび方法 Pending JP2015517677A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261651211P 2012-05-24 2012-05-24
US61/651,211 2012-05-24
US13/841,143 US10132736B2 (en) 2012-05-24 2013-03-15 Methods for inspection of protein particles in a liquid beneficial agent
US13/841,143 2013-03-15
PCT/US2013/042481 WO2013177434A2 (en) 2012-05-24 2013-05-23 Systems and methods for detection of particles in a beneficial agent

Publications (1)

Publication Number Publication Date
JP2015517677A true JP2015517677A (ja) 2015-06-22

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JP2015514197A Pending JP2015517677A (ja) 2012-05-24 2013-05-23 有益物質中の粒子の検出のためのシステムおよび方法

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Country Link
US (2) US10132736B2 (Direct)
EP (2) EP3835753A3 (Direct)
JP (1) JP2015517677A (Direct)
CN (1) CN104487816A (Direct)
CA (1) CA2873671A1 (Direct)
IN (1) IN2014DN09753A (Direct)
MX (1) MX337973B (Direct)
NZ (1) NZ631595A (Direct)
RU (1) RU2638913C2 (Direct)
SG (1) SG11201407660SA (Direct)
WO (1) WO2013177434A2 (Direct)
ZA (1) ZA201408386B (Direct)

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JP2019215376A (ja) * 2011-08-29 2019-12-19 アムジェン インコーポレイテッド 流体中の非溶解粒子の非破壊的検出のための方法および装置
JP2020056743A (ja) * 2018-10-04 2020-04-09 国立研究開発法人産業技術総合研究所 粒子測定装置、較正方法、および測定装置
WO2022168434A1 (ja) * 2021-02-05 2022-08-11 株式会社堀場製作所 粒子分析装置、粒子分析方法、及び、粒子分析装置用プログラム
JP7792180B1 (ja) * 2025-03-31 2025-12-25 株式会社シュヴァルベル 画像処理方法および粒子分析システム

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JP7139243B2 (ja) 2015-09-16 2022-09-20 サーモ エレクトロン サイエンティフィック インストルメンツ リミテッド ライアビリティ カンパニー 画像分析システム及び方法
CN114719977B (zh) 2016-04-21 2025-06-10 苹果公司 用于参考切换的光学系统
US20190154560A1 (en) 2016-05-16 2019-05-23 Abbvie Inc. Systems and Methods for Identifying Protein Aggregates in Biotherapeutics
DE102016012585A1 (de) * 2016-10-21 2018-04-26 Seidenader Maschinenbau Gmbh Vorrichtung zur Detektion von Luftblasen in einem mit Flüssigkeit befüllten Behälter
BR112019008270A8 (pt) * 2016-10-28 2023-04-11 Beckman Coulter Inc Sistema de avaliação de preparação de substância
CN106772975B (zh) * 2017-01-19 2019-08-13 宁波纳美致生物科技有限公司 针对细胞或组织不同深度超分辨率显微成像的照明系统
WO2018221605A1 (en) * 2017-05-31 2018-12-06 Nipro Corporation Method for evaluation of glass container
US11579080B2 (en) * 2017-09-29 2023-02-14 Apple Inc. Resolve path optical sampling architectures
SG11202007756XA (en) * 2018-03-30 2020-09-29 Amgen Inc Camera-based drug container inspection
JP7490655B2 (ja) * 2018-12-17 2024-05-27 アムジエン・インコーポレーテツド 医薬品容器における粒子検出のためのシート照明
CN109883905A (zh) * 2019-03-07 2019-06-14 南京理工大学 水下粒径在线测量系统及方法
US20210262849A1 (en) * 2020-02-24 2021-08-26 Des-Case Corporation Apparatuses, systems, and methods for providing a smart liquid information indicator
CN112730174A (zh) * 2020-12-17 2021-04-30 华南理工大学 一种实时监测结晶过程中类球形颗粒浓度的方法
JP7281500B2 (ja) * 2021-05-17 2023-05-25 東亜建設工業株式会社 画像データの取得方法および取得システム
US12518414B2 (en) * 2022-06-02 2026-01-06 University Of Central Florida Research Foundation, Inc. Systems and methods for image-based characterization of fluid in an enclosed container
TWI863605B (zh) * 2023-10-03 2024-11-21 住華科技股份有限公司 溶液的粒子濃度分佈的檢測方法
DE102025101336A1 (de) 2024-01-19 2025-07-24 Abbvie Inc. Zusammensetzungen von clostridium botulinum neurotoxin serotyp a und verbesserte trocknungsprozesse

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Cited By (13)

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Publication number Priority date Publication date Assignee Title
US11501458B2 (en) 2011-08-29 2022-11-15 Amgen Inc. Methods and apparati for nondestructive detection of undissolved particles in a fluid
US11803983B2 (en) 2011-08-29 2023-10-31 Amgen Inc. Methods and apparati for nondestructive detection of undissolved particles in a fluid
JP2019215376A (ja) * 2011-08-29 2019-12-19 アムジェン インコーポレイテッド 流体中の非溶解粒子の非破壊的検出のための方法および装置
TWI772897B (zh) * 2011-08-29 2022-08-01 美商安美基公司 用於非破壞性檢測-流體中未溶解粒子之方法及裝置
US11774340B2 (en) 2018-10-04 2023-10-03 National Institute Of Advanced Industrial Science And Technology Particle measuring device, calibration method, and measuring device
JP7116419B2 (ja) 2018-10-04 2022-08-10 国立研究開発法人産業技術総合研究所 粒子測定装置、較正方法、および測定装置
TWI810375B (zh) * 2018-10-04 2023-08-01 國立研究開發法人産業技術總合研究所 粒子測定裝置、校正方法以及測定裝置
KR20210066809A (ko) * 2018-10-04 2021-06-07 고쿠리츠켄큐카이하츠호진 상교기쥬츠 소고켄큐쇼 입자 측정 장치, 교정 방법, 및 측정 장치
JP2020056743A (ja) * 2018-10-04 2020-04-09 国立研究開発法人産業技術総合研究所 粒子測定装置、較正方法、および測定装置
KR102724822B1 (ko) 2018-10-04 2024-10-31 고쿠리츠켄큐카이하츠호진 상교기쥬츠 소고켄큐쇼 입자 측정 장치, 교정 방법, 및 측정 장치
WO2022168434A1 (ja) * 2021-02-05 2022-08-11 株式会社堀場製作所 粒子分析装置、粒子分析方法、及び、粒子分析装置用プログラム
JPWO2022168434A1 (Direct) * 2021-02-05 2022-08-11
JP7792180B1 (ja) * 2025-03-31 2025-12-25 株式会社シュヴァルベル 画像処理方法および粒子分析システム

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US10126226B2 (en) 2018-11-13
CA2873671A1 (en) 2013-11-28
ZA201408386B (en) 2015-11-25
NZ631595A (en) 2016-05-27
US20150226659A1 (en) 2015-08-13
CN104487816A (zh) 2015-04-01
US10132736B2 (en) 2018-11-20
US20130316934A1 (en) 2013-11-28
IN2014DN09753A (Direct) 2015-07-31
EP2856106A2 (en) 2015-04-08
MX337973B (es) 2016-03-29
WO2013177434A3 (en) 2014-01-30
WO2013177434A2 (en) 2013-11-28
RU2638913C2 (ru) 2017-12-18
RU2014152326A (ru) 2016-07-20
MX2014014340A (es) 2015-03-03
EP3835753A3 (en) 2021-09-22
EP3835753A2 (en) 2021-06-16
SG11201407660SA (en) 2014-12-30

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