MX2014014340A - Sistemas y metodos para detectar particulas en agente benefico. - Google Patents

Sistemas y metodos para detectar particulas en agente benefico.

Info

Publication number
MX2014014340A
MX2014014340A MX2014014340A MX2014014340A MX2014014340A MX 2014014340 A MX2014014340 A MX 2014014340A MX 2014014340 A MX2014014340 A MX 2014014340A MX 2014014340 A MX2014014340 A MX 2014014340A MX 2014014340 A MX2014014340 A MX 2014014340A
Authority
MX
Mexico
Prior art keywords
beneficial agent
image
liquid beneficial
particles
detection
Prior art date
Application number
MX2014014340A
Other languages
English (en)
Other versions
MX337973B (es
Inventor
Edmund Matayoshi
Jie Wang
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2014014340A publication Critical patent/MX2014014340A/es
Publication of MX337973B publication Critical patent/MX337973B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9018—Dirt detection in containers
    • G01N21/9027—Dirt detection in containers in containers after filling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/075—Investigating concentration of particle suspensions by optical means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a la detección de partículas en un agente benéfico líquido contenido en un recipiente (206), que incluye iluminar selectivamente al menos una porción del agente benéfico líquido, analizar los datos que representan la imagen, usar un procesador de datos (501) para obtener una concentración de partículas, medir un valor de intensidad de imagen de los datos de imagen empleando el procesador de datos (501), y determinar un nivel de calidad del agente benéfico líquido utilizando el procesador de datos (501), basándose en la concentración de partículas y en el valor de intensidad de imagen medido. El agente benéfico líquido puede ser un agente biológico, un producto farmacéutico de molécula pequeña, productos nutricionales, o combinaciones de los mismos. El recipiente puede ser una jeringa (206).
MX2014014340A 2012-05-24 2013-05-23 Sistemas y metodos para detectar particulas en agente benefico. MX337973B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651211P 2012-05-24 2012-05-24
US13/841,143 US10132736B2 (en) 2012-05-24 2013-03-15 Methods for inspection of protein particles in a liquid beneficial agent
PCT/US2013/042481 WO2013177434A2 (en) 2012-05-24 2013-05-23 Systems and methods for detection of particles in a beneficial agent

Publications (2)

Publication Number Publication Date
MX2014014340A true MX2014014340A (es) 2015-03-03
MX337973B MX337973B (es) 2016-03-29

Family

ID=49622069

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014340A MX337973B (es) 2012-05-24 2013-05-23 Sistemas y metodos para detectar particulas en agente benefico.

Country Status (12)

Country Link
US (2) US10132736B2 (es)
EP (2) EP2856106A2 (es)
JP (1) JP2015517677A (es)
CN (1) CN104487816A (es)
CA (1) CA2873671A1 (es)
IN (1) IN2014DN09753A (es)
MX (1) MX337973B (es)
NZ (1) NZ631595A (es)
RU (1) RU2638913C2 (es)
SG (1) SG11201407660SA (es)
WO (1) WO2013177434A2 (es)
ZA (1) ZA201408386B (es)

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TWI708052B (zh) 2011-08-29 2020-10-21 美商安美基公司 用於非破壞性檢測-流體中未溶解粒子之方法及裝置
AU2013387227B2 (en) * 2013-04-22 2018-08-16 Sanofi-Aventis Deutschland Gmbh Supplemental device for attachment to an injection device
GB2539504B (en) 2015-06-19 2019-04-17 Aqua21 Ltd Absorption Sensor for Measuring Substance Concentration
CN107969148B (zh) * 2015-09-16 2021-03-19 热电科学仪器有限公司 图像分析系统和方法
WO2017200939A1 (en) 2016-05-16 2017-11-23 Abbvie Inc. Systems and methods for identifying protein aggregates in biotherapeutics
DE102016012585A1 (de) * 2016-10-21 2018-04-26 Seidenader Maschinenbau Gmbh Vorrichtung zur Detektion von Luftblasen in einem mit Flüssigkeit befüllten Behälter
CN117253055A (zh) * 2016-10-28 2023-12-19 贝克曼库尔特有限公司 物质准备评估系统
CN106772975B (zh) * 2017-01-19 2019-08-13 宁波纳美致生物科技有限公司 针对细胞或组织不同深度超分辨率显微成像的照明系统
EP3630688A4 (en) * 2017-05-31 2021-02-24 Nipro Corporation GLASS CONTAINER EVALUATION PROCESS
US11499922B2 (en) * 2018-03-30 2022-11-15 Amgen Inc. Camera-based drug container inspection
JP7116419B2 (ja) * 2018-10-04 2022-08-10 国立研究開発法人産業技術総合研究所 粒子測定装置、較正方法、および測定装置
EP3899507A1 (en) * 2018-12-17 2021-10-27 Amgen Inc. Sheet lighting for particle detection in drug product containers
CN109883905A (zh) * 2019-03-07 2019-06-14 南京理工大学 水下粒径在线测量系统及方法
CN112730174A (zh) * 2020-12-17 2021-04-30 华南理工大学 一种实时监测结晶过程中类球形颗粒浓度的方法
JPWO2022168434A1 (es) * 2021-02-05 2022-08-11
JP7281500B2 (ja) * 2021-05-17 2023-05-25 東亜建設工業株式会社 画像データの取得方法および取得システム

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Also Published As

Publication number Publication date
US10132736B2 (en) 2018-11-20
CA2873671A1 (en) 2013-11-28
RU2014152326A (ru) 2016-07-20
EP3835753A2 (en) 2021-06-16
US20150226659A1 (en) 2015-08-13
JP2015517677A (ja) 2015-06-22
EP2856106A2 (en) 2015-04-08
WO2013177434A2 (en) 2013-11-28
IN2014DN09753A (es) 2015-07-31
US10126226B2 (en) 2018-11-13
EP3835753A3 (en) 2021-09-22
NZ631595A (en) 2016-05-27
RU2638913C2 (ru) 2017-12-18
WO2013177434A3 (en) 2014-01-30
CN104487816A (zh) 2015-04-01
US20130316934A1 (en) 2013-11-28
MX337973B (es) 2016-03-29
SG11201407660SA (en) 2014-12-30
ZA201408386B (en) 2015-11-25

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