MX337973B - Sistemas y metodos para detectar particulas en agente benefico. - Google Patents

Sistemas y metodos para detectar particulas en agente benefico.

Info

Publication number
MX337973B
MX337973B MX2014014340A MX2014014340A MX337973B MX 337973 B MX337973 B MX 337973B MX 2014014340 A MX2014014340 A MX 2014014340A MX 2014014340 A MX2014014340 A MX 2014014340A MX 337973 B MX337973 B MX 337973B
Authority
MX
Mexico
Prior art keywords
beneficial agent
image
liquid beneficial
particles
detection
Prior art date
Application number
MX2014014340A
Other languages
English (en)
Other versions
MX2014014340A (es
Inventor
Edmund Matayoshi
Jie Wang
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2014014340A publication Critical patent/MX2014014340A/es
Publication of MX337973B publication Critical patent/MX337973B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/90—Investigating the presence of flaws or contamination in a container or its contents
    • G01N21/9018—Dirt detection in containers
    • G01N21/9027—Dirt detection in containers in containers after filling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/075—Investigating concentration of particle suspensions by optical means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a la detección de partículas en un agente benéfico líquido contenido en un recipiente (206), que incluye iluminar selectivamente al menos una porción del agente benéfico líquido, analizar los datos que representan la imagen, usar un procesador de datos (501) para obtener una concentración de partículas, medir un valor de intensidad de imagen de los datos de imagen empleando el procesador de datos (501), y determinar un nivel de calidad del agente benéfico líquido utilizando el procesador de datos (501), basándose en la concentración de partículas y en el valor de intensidad de imagen medido. El agente benéfico líquido puede ser un agente biológico, un producto farmacéutico de molécula pequeña, productos nutricionales, o combinaciones de los mismos. El recipiente puede ser una jeringa (206).
MX2014014340A 2012-05-24 2013-05-23 Sistemas y metodos para detectar particulas en agente benefico. MX337973B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651211P 2012-05-24 2012-05-24
US13/841,143 US10132736B2 (en) 2012-05-24 2013-03-15 Methods for inspection of protein particles in a liquid beneficial agent
PCT/US2013/042481 WO2013177434A2 (en) 2012-05-24 2013-05-23 Systems and methods for detection of particles in a beneficial agent

Publications (2)

Publication Number Publication Date
MX2014014340A MX2014014340A (es) 2015-03-03
MX337973B true MX337973B (es) 2016-03-29

Family

ID=49622069

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014014340A MX337973B (es) 2012-05-24 2013-05-23 Sistemas y metodos para detectar particulas en agente benefico.

Country Status (12)

Country Link
US (2) US10132736B2 (es)
EP (2) EP2856106A2 (es)
JP (1) JP2015517677A (es)
CN (1) CN104487816A (es)
CA (1) CA2873671A1 (es)
IN (1) IN2014DN09753A (es)
MX (1) MX337973B (es)
NZ (1) NZ631595A (es)
RU (1) RU2638913C2 (es)
SG (1) SG11201407660SA (es)
WO (1) WO2013177434A2 (es)
ZA (1) ZA201408386B (es)

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DK2988800T3 (da) * 2013-04-22 2017-11-13 Sanofi Aventis Deutschland Supplerende anordning til fastgørelse til en injektionsanordning
GB2539504B (en) 2015-06-19 2019-04-17 Aqua21 Ltd Absorption Sensor for Measuring Substance Concentration
EP3350574B1 (en) 2015-09-16 2021-12-15 Thermo Electron Scientific Instruments LLC Image analysis system and method
WO2017200939A1 (en) 2016-05-16 2017-11-23 Abbvie Inc. Systems and methods for identifying protein aggregates in biotherapeutics
DE102016012585A1 (de) * 2016-10-21 2018-04-26 Seidenader Maschinenbau Gmbh Vorrichtung zur Detektion von Luftblasen in einem mit Flüssigkeit befüllten Behälter
CN117058415A (zh) * 2016-10-28 2023-11-14 贝克曼库尔特有限公司 物质准备评估系统
CN106772975B (zh) * 2017-01-19 2019-08-13 宁波纳美致生物科技有限公司 针对细胞或组织不同深度超分辨率显微成像的照明系统
WO2018221605A1 (en) 2017-05-31 2018-12-06 Nipro Corporation Method for evaluation of glass container
WO2019067796A2 (en) * 2017-09-29 2019-04-04 Masseta Technologies Llc OPTICAL SAMPLING ARCHITECTURES OF RESOLUTION PATH
SG11202007756XA (en) * 2018-03-30 2020-09-29 Amgen Inc Camera-based drug container inspection
JP7116419B2 (ja) * 2018-10-04 2022-08-10 国立研究開発法人産業技術総合研究所 粒子測定装置、較正方法、および測定装置
IL282863B2 (en) * 2018-12-17 2025-02-01 Amgen Inc Sheet illumination for particle detection in pharmaceutical containers
CN109883905A (zh) * 2019-03-07 2019-06-14 南京理工大学 水下粒径在线测量系统及方法
US20210262849A1 (en) * 2020-02-24 2021-08-26 Des-Case Corporation Apparatuses, systems, and methods for providing a smart liquid information indicator
CN112730174A (zh) * 2020-12-17 2021-04-30 华南理工大学 一种实时监测结晶过程中类球形颗粒浓度的方法
JPWO2022168434A1 (es) * 2021-02-05 2022-08-11
JP7281500B2 (ja) * 2021-05-17 2023-05-25 東亜建設工業株式会社 画像データの取得方法および取得システム
US20230394696A1 (en) * 2022-06-02 2023-12-07 University Of Central Florida Research Foundation, Inc. Systems and methods for image-based characterization of fluid in an enclosed container
TWI863605B (zh) * 2023-10-03 2024-11-21 住華科技股份有限公司 溶液的粒子濃度分佈的檢測方法
DE102025101336A1 (de) 2024-01-19 2025-07-24 Abbvie Inc. Zusammensetzungen von clostridium botulinum neurotoxin serotyp a und verbesserte trocknungsprozesse

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Also Published As

Publication number Publication date
ZA201408386B (en) 2015-11-25
SG11201407660SA (en) 2014-12-30
RU2638913C2 (ru) 2017-12-18
WO2013177434A3 (en) 2014-01-30
EP3835753A3 (en) 2021-09-22
US20130316934A1 (en) 2013-11-28
JP2015517677A (ja) 2015-06-22
WO2013177434A2 (en) 2013-11-28
NZ631595A (en) 2016-05-27
EP3835753A2 (en) 2021-06-16
US20150226659A1 (en) 2015-08-13
US10132736B2 (en) 2018-11-20
EP2856106A2 (en) 2015-04-08
US10126226B2 (en) 2018-11-13
MX2014014340A (es) 2015-03-03
CN104487816A (zh) 2015-04-01
IN2014DN09753A (es) 2015-07-31
CA2873671A1 (en) 2013-11-28
RU2014152326A (ru) 2016-07-20

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