JP2015517466A5 - - Google Patents

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Publication number
JP2015517466A5
JP2015517466A5 JP2015510380A JP2015510380A JP2015517466A5 JP 2015517466 A5 JP2015517466 A5 JP 2015517466A5 JP 2015510380 A JP2015510380 A JP 2015510380A JP 2015510380 A JP2015510380 A JP 2015510380A JP 2015517466 A5 JP2015517466 A5 JP 2015517466A5
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JP
Japan
Prior art keywords
rnai agent
composition
kras
strand
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015510380A
Other languages
English (en)
Japanese (ja)
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JP2015517466A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/038847 external-priority patent/WO2013166004A2/en
Publication of JP2015517466A publication Critical patent/JP2015517466A/ja
Publication of JP2015517466A5 publication Critical patent/JP2015517466A5/ja
Pending legal-status Critical Current

Links

JP2015510380A 2012-05-02 2013-04-30 Ｋｒａｓ関連疾患を処置するための有機組成物 Pending JP2015517466A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261641588P 2012-05-02 2012-05-02
US61/641,588 2012-05-02
PCT/US2013/038847 WO2013166004A2 (en) 2012-05-02 2013-04-30 Organic compositions to treat kras-related diseases

Publications (2)

Publication Number Publication Date
JP2015517466A JP2015517466A (ja) 2015-06-22
JP2015517466A5 true JP2015517466A5 (https=) 2016-06-23

Family

ID=48366565

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015510380A Pending JP2015517466A (ja) 2012-05-02 2013-04-30 Ｋｒａｓ関連疾患を処置するための有機組成物

Country Status (12)

Country Link
US (3) US20150238515A1 (https=)
EP (3) EP2844757A2 (https=)
JP (1) JP2015517466A (https=)
KR (1) KR20150004414A (https=)
CN (2) CN109481455A (https=)
AU (5) AU2013256471A1 (https=)
BR (1) BR112014027337A2 (https=)
CA (2) CA2872304C (https=)
EA (1) EA201492004A1 (https=)
HK (1) HK1206387A1 (https=)
MX (1) MX2014013367A (https=)
WO (1) WO2013166004A2 (https=)

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KR102589295B1 (ko) 2014-05-14 2023-10-13 타르그이뮨 테라퓨틱스 아게 개선된 폴리에틸렌이민 폴리에틸렌글리콜 벡터
US11180759B2 (en) * 2016-01-19 2021-11-23 The University Of North Carolina At Chapel Hill Methods and compositions using RNA interference and antisense oligonucleotides for inhibition of KRAS
JP2019513371A (ja) 2016-04-01 2019-05-30 アビディティー バイオサイエンシーズ エルエルシー 核酸ポリペプチド組成物とその使用
EP3436585B1 (en) * 2016-04-01 2022-07-20 Avidity Biosciences, Inc. Kras nucleic acids and uses thereof
KR102543645B1 (ko) * 2016-07-20 2023-06-16 주식회사 지씨지놈 유전성 발달장애 진단용 조성물 및 이의 용도
AU2018378812B2 (en) 2017-12-06 2025-05-22 Avidity Biosciences, Inc. Compositions and methods of treating muscle atrophy and myotonic dystrophy
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WO2021188390A1 (en) 2020-03-19 2021-09-23 Avidity Biosciences, Inc. Compositions and methods of treating facioscapulohumeral muscular dystrophy
JP7839554B2 (ja) * 2020-04-07 2026-04-02 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル Ｋｒａｓの阻害のためのｒｎａ干渉およびアンチセンスオリゴヌクレオチドを使用する方法および組成物
KR20240051272A (ko) * 2021-09-02 2024-04-19 몰레큘라 악시옴, 엘엘씨 Kras 발현을 조절하기 위한 조성물 및 방법
CN118265544A (zh) 2021-09-16 2024-06-28 艾维迪提生物科学公司 治疗面肩肱型肌营养不良的组合物和方法
EP4652279A2 (en) * 2023-01-18 2025-11-26 Molecular Axiom, LLC Compositions for modulating kras expression and uses thereof
AU2024225428A1 (en) * 2023-02-22 2025-08-28 Altamira Therapeutics Ag Compositions and methods for kras inhibition for the treatment of disease
WO2026026715A1 (zh) * 2024-07-31 2026-02-05 前沿生物药业(南京)股份有限公司 一种用于抑制KRAS基因表达的siRNA及其修饰物与应用

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