JP2015511613A5 - - Google Patents
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- Publication number
- JP2015511613A5 JP2015511613A5 JP2015502285A JP2015502285A JP2015511613A5 JP 2015511613 A5 JP2015511613 A5 JP 2015511613A5 JP 2015502285 A JP2015502285 A JP 2015502285A JP 2015502285 A JP2015502285 A JP 2015502285A JP 2015511613 A5 JP2015511613 A5 JP 2015511613A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- replaced
- cycloalkyl
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12161240.2 | 2012-03-26 | ||
| EP12161240 | 2012-03-26 | ||
| PCT/EP2013/056313 WO2013144098A1 (en) | 2012-03-26 | 2013-03-25 | New indanyloxydihydrobenzofuranylacetic acid derivatives and their use as gpr40 receptor agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015511613A JP2015511613A (ja) | 2015-04-20 |
| JP2015511613A5 true JP2015511613A5 (https=) | 2016-05-19 |
| JP6131492B2 JP6131492B2 (ja) | 2017-05-24 |
Family
ID=48013980
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015502285A Expired - Fee Related JP6131492B2 (ja) | 2012-03-26 | 2013-03-25 | 新しいインダニルオキシジヒドロベンゾフラニル酢酸誘導体およびｇｐｒ４０受容体作動薬としてのそれらの使用 |
| JP2015502284A Active JP6040486B2 (ja) | 2012-03-26 | 2013-03-25 | 新しいインダニルオキシジヒドロベンゾフラニル酢酸誘導体およびｇｐｒ４０受容体作動薬としてのそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015502284A Active JP6040486B2 (ja) | 2012-03-26 | 2013-03-25 | 新しいインダニルオキシジヒドロベンゾフラニル酢酸誘導体およびｇｐｒ４０受容体作動薬としてのそれらの使用 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8642585B2 (https=) |
| EP (2) | EP2831053B1 (https=) |
| JP (2) | JP6131492B2 (https=) |
| KR (1) | KR20140139088A (https=) |
| CN (1) | CN104321319A (https=) |
| AP (1) | AP2014007903A0 (https=) |
| AR (1) | AR090493A1 (https=) |
| AU (1) | AU2013241926A1 (https=) |
| CA (1) | CA2868474A1 (https=) |
| CL (1) | CL2014002556A1 (https=) |
| CO (1) | CO7091175A2 (https=) |
| EA (1) | EA201401053A1 (https=) |
| EC (1) | ECSP14023238A (https=) |
| HK (1) | HK1201260A1 (https=) |
| MA (1) | MA20150065A1 (https=) |
| MX (1) | MX2014011465A (https=) |
| PE (1) | PE20142019A1 (https=) |
| PH (1) | PH12014502141A1 (https=) |
| SG (1) | SG11201405713UA (https=) |
| TN (1) | TN2014000398A1 (https=) |
| TW (1) | TW201400466A (https=) |
| UY (1) | UY34704A (https=) |
| WO (2) | WO2013144098A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR084050A1 (es) * | 2010-12-01 | 2013-04-17 | Boehringer Ingelheim Int | Acidos indaniloxidihidrobenzofuranilaceticos |
| US8642585B2 (en) * | 2012-03-26 | 2014-02-04 | Boehringer Ingelheim International Gmbh | Indanyloxydihydrobenzofuranylacetic acids |
| CN105473595A (zh) * | 2013-08-23 | 2016-04-06 | 福建海西新药创制有限公司 | 治疗糖尿病的羧酸化合物 |
| IN2013MU03577A (https=) | 2013-11-14 | 2015-07-31 | Cadila Healthcare Ltd | |
| EP3076959B1 (en) | 2013-12-04 | 2018-07-04 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| EP3102198B1 (en) | 2014-02-06 | 2020-08-26 | Merck Sharp & Dohme Corp. | Antidiabetic compounds |
| WO2016022446A1 (en) * | 2014-08-08 | 2016-02-11 | Merck Sharp & Dohme Corp. | [5,6]-fused bicyclic antidiabetic compounds |
| US20180354962A1 (en) * | 2015-09-09 | 2018-12-13 | Boehringer Ingelheim International Gmbh | [{[2,3-Dihydro-1H-inden-1-yl]amino}-2H,3H-furo[3,2-b]pyridin-3-yl]acetic acids, pharmaceutical compositions and uses thereof |
| US10125101B2 (en) | 2016-11-28 | 2018-11-13 | Boehringer Ingelheim International Gmbh | Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| JP7050792B2 (ja) | 2017-01-26 | 2022-04-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ベンジルオキシピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用 |
| US10913720B2 (en) | 2017-01-26 | 2021-02-09 | Boehringer Ingelheim International Gmbh | Benzyloxypyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| EP3573959B1 (en) | 2017-01-26 | 2021-07-28 | Boehringer Ingelheim International GmbH | Benzylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| CN110177773B (zh) | 2017-01-26 | 2023-08-25 | 勃林格殷格翰国际有限公司 | 苄基氨基吡啶基环丙烷羧酸、其药物组合物及其用途 |
| CN110214135B (zh) | 2017-01-26 | 2023-02-21 | 勃林格殷格翰国际有限公司 | 茚满基氨基吡嗪基环丙烷羧酸、药物组合物及其用途 |
| US10550127B1 (en) | 2017-02-08 | 2020-02-04 | Boehringer Ingelheim International Gmbh | Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes |
| JPWO2018181847A1 (ja) * | 2017-03-31 | 2020-03-05 | 武田薬品工業株式会社 | 芳香環化合物 |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| CN111479795A (zh) * | 2017-12-04 | 2020-07-31 | 巴斯夫欧洲公司 | 制备环脂族或芳脂族二醇的醚的方法 |
| WO2019149959A1 (en) * | 2018-02-05 | 2019-08-08 | Glaxosmithkline Intellectual Property Development Limited | Ghrelin o-acyltransferase inhibitors |
| TWI707849B (zh) | 2018-02-13 | 2020-10-21 | 美商基利科學股份有限公司 | Pd‐1/pd‐l1抑制劑 |
| US12083118B2 (en) | 2018-03-29 | 2024-09-10 | Arbutus Biopharma Corporation | Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same |
| KR102591947B1 (ko) | 2018-04-19 | 2023-10-25 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| EP3820572B1 (en) | 2018-07-13 | 2023-08-16 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| US20210236476A1 (en) * | 2018-08-29 | 2021-08-05 | Chemocentryx, Inc. | Methods of treating cancer with small molecule pd-l1 inhibitors |
| TW202028183A (zh) * | 2018-10-10 | 2020-08-01 | 大陸商江蘇豪森藥業集團有限公司 | 含氮雜芳類衍生物調節劑、其製備方法和應用 |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| JP2022552655A (ja) | 2019-10-07 | 2022-12-19 | キャリーオペ，インク． | Ｇｐｒ１１９アゴニスト |
| IL295825A (en) | 2020-02-28 | 2022-10-01 | Kallyope Inc | gpr40 agonists |
| WO2021236617A1 (en) | 2020-05-19 | 2021-11-25 | Kallyope, Inc. | Ampk activators |
| CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4594611B2 (ja) * | 2002-11-08 | 2010-12-08 | 武田薬品工業株式会社 | 受容体機能調節剤 |
| AU2003277576A1 (en) * | 2002-11-08 | 2004-06-07 | Takeda Pharmaceutical Company Limited | Receptor function controlling agent |
| CN1735408A (zh) * | 2002-11-08 | 2006-02-15 | 武田药品工业株式会社 | 受体机能调节剂 |
| JP4805552B2 (ja) * | 2003-05-30 | 2011-11-02 | 武田薬品工業株式会社 | 縮合環化合物 |
| EP1630152A4 (en) | 2003-05-30 | 2009-09-23 | Takeda Pharmaceutical | CONDENSED CYCLIC COMPOUND |
| EP2006271A4 (en) | 2006-03-30 | 2011-08-10 | Asahi Kasei Pharma Corp | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF |
| BRPI0713378A8 (pt) * | 2006-06-27 | 2018-01-02 | Takeda Pharmaceutical | composto, pró-droga, modulador da função do receptor gpr40, agente farmacêutico uso do composto, e, método de produção de uma forma opticamente ativa de um composto |
| NZ588983A (en) | 2008-06-25 | 2011-11-25 | Daiichi Sankyo Co Ltd | Carboxylic acid compound |
| AU2009303475B2 (en) | 2008-10-15 | 2012-09-13 | Amgen Inc. | Spirocyclic GPR40 modulators |
| WO2010143733A1 (en) | 2009-06-09 | 2010-12-16 | Takeda Pharmaceutical Company Limited | Novel fused cyclic compound and use thereof |
| TW201643169A (zh) * | 2010-07-09 | 2016-12-16 | 艾伯維股份有限公司 | 作為s1p調節劑的螺-哌啶衍生物 |
| AR084050A1 (es) | 2010-12-01 | 2013-04-17 | Boehringer Ingelheim Int | Acidos indaniloxidihidrobenzofuranilaceticos |
| US8642585B2 (en) * | 2012-03-26 | 2014-02-04 | Boehringer Ingelheim International Gmbh | Indanyloxydihydrobenzofuranylacetic acids |
-
2013
- 2013-03-14 US US13/803,237 patent/US8642585B2/en active Active
- 2013-03-22 UY UY0001034704A patent/UY34704A/es unknown
- 2013-03-25 SG SG11201405713UA patent/SG11201405713UA/en unknown
- 2013-03-25 AU AU2013241926A patent/AU2013241926A1/en not_active Abandoned
- 2013-03-25 HK HK15101722.6A patent/HK1201260A1/xx unknown
- 2013-03-25 CN CN201380026597.0A patent/CN104321319A/zh active Pending
- 2013-03-25 JP JP2015502285A patent/JP6131492B2/ja not_active Expired - Fee Related
- 2013-03-25 TW TW102110560A patent/TW201400466A/zh unknown
- 2013-03-25 KR KR20147030011A patent/KR20140139088A/ko not_active Withdrawn
- 2013-03-25 JP JP2015502284A patent/JP6040486B2/ja active Active
- 2013-03-25 WO PCT/EP2013/056313 patent/WO2013144098A1/en not_active Ceased
- 2013-03-25 PE PE2014001462A patent/PE20142019A1/es not_active Application Discontinuation
- 2013-03-25 EP EP13724175.8A patent/EP2831053B1/en not_active Not-in-force
- 2013-03-25 WO PCT/EP2013/056312 patent/WO2013144097A1/en not_active Ceased
- 2013-03-25 AR ARP130100969A patent/AR090493A1/es unknown
- 2013-03-25 CA CA2868474A patent/CA2868474A1/en not_active Abandoned
- 2013-03-25 AP AP2014007903A patent/AP2014007903A0/xx unknown
- 2013-03-25 EP EP13712760.1A patent/EP2831064B1/en active Active
- 2013-03-25 EA EA201401053A patent/EA201401053A1/ru unknown
- 2013-03-25 MX MX2014011465A patent/MX2014011465A/es unknown
- 2013-03-25 MA MA37429A patent/MA20150065A1/fr unknown
-
2014
- 2014-09-22 TN TNP2014000398A patent/TN2014000398A1/fr unknown
- 2014-09-25 PH PH12014502141A patent/PH12014502141A1/en unknown
- 2014-09-25 CL CL2014002556A patent/CL2014002556A1/es unknown
- 2014-09-26 CO CO14213969A patent/CO7091175A2/es unknown
- 2014-10-17 EC ECIEPI201423238A patent/ECSP14023238A/es unknown