|
JP6067226B2
(ja)
|
2009-03-13 |
2017-01-25 |
アジオス ファーマシューティカルズ， インコーポレイテッド |
細胞増殖関連疾患のための方法および組成物
|
|
AR077292A1
(es)
|
2009-06-29 |
2011-08-17 |
Agios Pharmaceuticals Inc |
Derivados de piperazin - quinolin sulfonamidas y composiciones farmaceuticas
|
|
ES2594402T3
(es)
|
2009-10-21 |
2016-12-20 |
Agios Pharmaceuticals, Inc. |
Métodos y composiciones para trastornos relacionados con la proliferación celular
|
|
HUE065700T2
(hu)
|
2011-05-03 |
2024-06-28 |
Agios Pharmaceuticals Inc |
Piruvát-kináz aktivátorok terápiában történõ alkalmazásra
|
|
CN102827073A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
CN102827170A
(zh)
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
|
CA2860623A1
(en)
|
2012-01-06 |
2013-07-11 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
US9474779B2
(en)
|
2012-01-19 |
2016-10-25 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compositions and their methods of use
|
|
JP6385352B2
(ja)
|
2012-10-15 |
2018-09-05 |
アジオス ファーマシューティカルズ， インコーポレイテッド |
治療化合物および組成物
|
|
US9579324B2
(en)
|
2013-07-11 |
2017-02-28 |
Agios Pharmaceuticals, Inc |
Therapeutically active compounds and their methods of use
|
|
WO2015003360A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
SG11201600058XA
(en)
|
2013-07-11 |
2016-02-26 |
Agios Pharmaceuticals Inc |
N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer
|
|
WO2015003355A2
(en)
|
2013-07-11 |
2015-01-15 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
AU2014287121B2
(en)
|
2013-07-11 |
2018-11-15 |
Agios Pharmaceuticals, Inc. |
2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer
|
|
US20150031627A1
(en)
|
2013-07-25 |
2015-01-29 |
Agios Pharmaceuticals, Inc |
Therapeutically active compounds and their methods of use
|
|
WO2015010297A1
(en)
*
|
2013-07-25 |
2015-01-29 |
Agios Pharmaceuticals, Inc. |
Therapeutically active compounds and their methods of use
|
|
KR101861869B1
(ko)
*
|
2013-09-10 |
2018-05-28 |
경희대학교 산학협력단 |
신규한 비스-아미드 유도체 및 이의 용도
|
|
CN103694142A
(zh)
*
|
2013-11-28 |
2014-04-02 |
浙江科技学院 |
4-N-Boc-氨基环己酮的制备方法
|
|
CA2942072C
(en)
|
2014-03-14 |
2022-07-26 |
Agios Pharmaceuticals, Inc. |
Pharmaceutical compositions and use of (s)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-( 4-cyanopyridin-2-yl)-n-( 5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
|
|
AU2015240465B2
(en)
|
2014-04-04 |
2020-02-27 |
Del Mar Pharmaceuticals |
Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
|
|
AU2015325279B2
(en)
|
2014-10-01 |
2020-02-27 |
Daiichi Sankyo Company, Limited |
Isoxazole derivative as mutant isocitrate dehydrogenase 1 inhibitor
|
|
US10138226B2
(en)
*
|
2014-10-23 |
2018-11-27 |
Bayer Pharma Aktiengesellschaft |
Benzimidazol-2-amines as MIDH1 inhibitors
|
|
US10086000B2
(en)
|
2014-12-05 |
2018-10-02 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds as inhibitors of mutant IDH enzymes
|
|
PL3307271T3
(pl)
|
2015-06-11 |
2024-02-05 |
Agios Pharmaceuticals, Inc. |
Sposoby stosowania aktywatorów kinazy pirogronianowej
|
|
RS62829B1
(sr)
|
2015-10-15 |
2022-02-28 |
Servier Lab |
Kombinovana terapija za lečenje maligniteta
|
|
IL258684B2
(en)
|
2015-10-15 |
2023-04-01 |
Agios Pharmaceuticals Inc |
Combination therapy including an isocitrate dehydrogenase (1idh) inhibitor for use in the treatment of acute myelogenous leukemia (aml) characterized by the presence of a mutant allele of 1idh
|
|
WO2017140758A1
(en)
|
2016-02-19 |
2017-08-24 |
Debiopharm International S.A. |
Derivatives of 2-amino-4-(2-oxazolidinon-3-yl)-pyrimidine fused with a five-membered heteroaromatic ring in 5,6-position which are useful for the treatment of various cancers
|
|
WO2017162156A1
(zh)
*
|
2016-03-22 |
2017-09-28 |
正大天晴药业集团股份有限公司 |
丙啶磺酰胺类化合物及其使用方法
|
|
CN113666922A
(zh)
*
|
2016-03-22 |
2021-11-19 |
正大天晴药业集团股份有限公司 |
内磺酰胺化合物及其使用方法
|
|
MX379576B
(es)
*
|
2017-02-28 |
2025-03-11 |
Chia Tai Tianqing Pharmaceutical Group Co Ltd |
Derivados de azetidina
|
|
JP6951562B2
(ja)
*
|
2017-09-22 |
2021-10-20 |
チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッドChia Tai Tianqing Pharmaceutical Group Co., Ltd. |
環状スルホンアミド化合物の結晶
|
|
CN107827880B
(zh)
*
|
2017-10-17 |
2020-05-22 |
浙江工业大学上虞研究院有限公司 |
一种含咪唑和1,3,4-噁二唑结构的甲腈类化合物及其制备方法和应用
|
|
US11013733B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mlDH-1)
|
|
US11013734B2
(en)
|
2018-05-16 |
2021-05-25 |
Forma Therapeutics, Inc. |
Treating patients harboring an isocitrate dehydrogenase-1 (IDH-1) mutation
|
|
WO2019222553A1
(en)
|
2018-05-16 |
2019-11-21 |
Forma Therapeutics, Inc. |
Inhibiting mutant idh-1
|
|
US11311527B2
(en)
|
2018-05-16 |
2022-04-26 |
Forma Therapeutics, Inc. |
Inhibiting mutant isocitrate dehydrogenase 1 (mIDH-1)
|
|
US10532047B2
(en)
|
2018-05-16 |
2020-01-14 |
Forma Therapeutics, Inc. |
Solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile
|
|
US10980788B2
(en)
|
2018-06-08 |
2021-04-20 |
Agios Pharmaceuticals, Inc. |
Therapy for treating malignancies
|
|
CN109535025B
(zh)
*
|
2018-12-18 |
2022-09-09 |
尚科生物医药（上海）有限公司 |
一种艾伏尼布中间体3,3-二氟环丁胺盐酸盐的制备方法
|
|
WO2020127887A1
(en)
*
|
2018-12-21 |
2020-06-25 |
Sandoz Ag |
Process for the preparation of an intermediate product of ivosidenib
|
|
ES2965468T3
(es)
*
|
2019-08-09 |
2024-04-15 |
Artios Pharma Ltd |
Compuestos heterocíclicos para uso en el tratamiento del cáncer
|
|
TW202120486A
(zh)
*
|
2019-08-09 |
2021-06-01 |
英商阿帝歐斯製藥有限公司 |
新穎化合物
|
|
WO2022026565A1
(en)
*
|
2020-07-29 |
2022-02-03 |
Ideaya Biosciences, Inc. |
Cyclized acetamido derivatives as dna polymerase theta inhibitors
|
|
US20240025849A1
(en)
*
|
2020-08-26 |
2024-01-25 |
Max Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft |
Inhibitors of no production
|
|
WO2023241322A1
(en)
*
|
2022-06-16 |
2023-12-21 |
Danatlas Pharmaceuticals Co., Ltd. |
Heterocyclic derivatives, compositions and uses thereof
|
|
WO2024153143A1
(zh)
*
|
2023-01-18 |
2024-07-25 |
中国药科大学 |
含氮并环类化合物及其应用
|