JP2015506961A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015506961A5 JP2015506961A5 JP2014555801A JP2014555801A JP2015506961A5 JP 2015506961 A5 JP2015506961 A5 JP 2015506961A5 JP 2014555801 A JP2014555801 A JP 2014555801A JP 2014555801 A JP2014555801 A JP 2014555801A JP 2015506961 A5 JP2015506961 A5 JP 2015506961A5
- Authority
- JP
- Japan
- Prior art keywords
- renal cell
- cell carcinoma
- optionally
- therapeutic agent
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261593864P | 2012-02-02 | 2012-02-02 | |
| US61/593,864 | 2012-02-02 | ||
| US201261597124P | 2012-02-09 | 2012-02-09 | |
| US61/597,124 | 2012-02-09 | ||
| PCT/US2013/024510 WO2013116781A1 (en) | 2012-02-02 | 2013-02-01 | Alk1 antagonists and their uses in treating renal cell carcinoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015506961A JP2015506961A (ja) | 2015-03-05 |
| JP2015506961A5 true JP2015506961A5 (https=) | 2016-03-17 |
Family
ID=48903082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014555801A Pending JP2015506961A (ja) | 2012-02-02 | 2013-02-01 | Ａｌｋ１アンタゴニストおよび腎細胞癌の治療におけるその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130202594A1 (https=) |
| EP (1) | EP2809335A4 (https=) |
| JP (1) | JP2015506961A (https=) |
| KR (1) | KR20140123558A (https=) |
| CN (1) | CN104321070A (https=) |
| AU (1) | AU2013214779A1 (https=) |
| BR (1) | BR112014019151A2 (https=) |
| CA (1) | CA2863188A1 (https=) |
| MX (1) | MX2014009277A (https=) |
| RU (1) | RU2633638C2 (https=) |
| WO (1) | WO2013116781A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111518218A (zh) | 2006-11-02 | 2020-08-11 | 阿塞勒隆制药公司 | Alk1受体和配体拮抗剂及其用途 |
| US10059756B2 (en) | 2006-11-02 | 2018-08-28 | Acceleron Pharma Inc. | Compositions comprising ALK1-ECD protein |
| US8642031B2 (en) | 2006-11-02 | 2014-02-04 | Acceleron Pharma, Inc. | Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof |
| WO2015147908A1 (en) * | 2014-03-28 | 2015-10-01 | Acceleron Pharma, Inc. | Use of activin receptor-like kinase 1 (alk-1) antagonists in the treatment of cancer |
| JP2016036322A (ja) * | 2014-08-11 | 2016-03-22 | 日本化薬株式会社 | 血管新生因子と結合するキメラタンパク質 |
| EP3268025B1 (en) * | 2015-03-10 | 2020-05-06 | University of Massachusetts | Targeting gdf6 and bmp signaling for anti-melanoma therapy |
| EP3303387A2 (en) | 2015-06-05 | 2018-04-11 | Novartis AG | Antibodies targeting bone morphogenetic protein 9 (bmp9) and methods therefor |
| CN106994181A (zh) * | 2017-03-10 | 2017-08-01 | 上海交通大学医学院附属第九人民医院 | Bmp9在制备延缓肝纤维化药物中的应用 |
| MY206158A (en) | 2017-05-24 | 2024-12-02 | Novartis Ag | Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer |
| WO2019173482A1 (en) * | 2018-03-06 | 2019-09-12 | Sanford Burnham Prebys Medical Discovery Institute | 4-aminoquinoline compounds for the treatment of angiogenesis |
| US20250002588A1 (en) | 2023-04-07 | 2025-01-02 | Diagonal Therapeutics Inc. | Bispecific agonistic antibodies to activin a receptor like type 1 (alk1) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8529014D0 (en) | 1985-11-25 | 1986-01-02 | Biogen Nv | Enhanced secretion of heterologous proteins |
| WO1987005330A1 (en) | 1986-03-07 | 1987-09-11 | Michel Louis Eugene Bergh | Method for enhancing glycoprotein stability |
| US6858598B1 (en) * | 1998-12-23 | 2005-02-22 | G. D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US20070105887A1 (en) | 2005-11-04 | 2007-05-10 | Wyeth | Antineoplastic combinations of temsirolimus and sunitinib malate |
| WO2008008981A1 (en) * | 2006-07-13 | 2008-01-17 | Zymogenetics, Inc. | Interleukin 21 and tyrosine kinase inhibitor combination therapy |
| CN111518218A (zh) * | 2006-11-02 | 2020-08-11 | 阿塞勒隆制药公司 | Alk1受体和配体拮抗剂及其用途 |
| MX2009012934A (es) * | 2007-06-01 | 2009-12-15 | Wyeth Corp | Metodos y composiciones para modular la actividad de bmp-10. |
| KR20100090683A (ko) * | 2007-11-09 | 2010-08-16 | 제넨테크, 인크. | 액티빈 수용체-유사 키나제-ｉ 길항제 조성물 및 사용 방법 |
| WO2009128083A1 (en) * | 2008-04-16 | 2009-10-22 | Natco Pharma Limited | Novel polymorphic forms of sunitinib base |
| JP5719766B2 (ja) * | 2008-05-02 | 2015-05-20 | アクセルロン ファーマ， インコーポレイテッド | 血管新生および周皮細胞組成物を調節するための方法および組成物 |
| US7998973B2 (en) * | 2009-11-13 | 2011-08-16 | Aveo Pharmaceuticals, Inc. | Tivozanib and temsirolimus in combination |
| EP2558122A4 (en) * | 2010-04-15 | 2014-03-05 | Vegenics Pty Ltd | COMBINATION TREATMENT WITH VEGF-C ANTAGONISTS |
-
2013
- 2013-02-01 WO PCT/US2013/024510 patent/WO2013116781A1/en not_active Ceased
- 2013-02-01 MX MX2014009277A patent/MX2014009277A/es unknown
- 2013-02-01 KR KR1020147024468A patent/KR20140123558A/ko not_active Withdrawn
- 2013-02-01 EP EP13744185.3A patent/EP2809335A4/en not_active Withdrawn
- 2013-02-01 AU AU2013214779A patent/AU2013214779A1/en not_active Abandoned
- 2013-02-01 CN CN201380013788.3A patent/CN104321070A/zh active Pending
- 2013-02-01 BR BR112014019151A patent/BR112014019151A2/pt not_active Application Discontinuation
- 2013-02-01 US US13/757,672 patent/US20130202594A1/en not_active Abandoned
- 2013-02-01 JP JP2014555801A patent/JP2015506961A/ja active Pending
- 2013-02-01 RU RU2014134923A patent/RU2633638C2/ru not_active IP Right Cessation
- 2013-02-01 CA CA2863188A patent/CA2863188A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015506961A5 (https=) | ||
| Jiang et al. | cGAS-STING, an important pathway in cancer immunotherapy | |
| Peters et al. | Addressing CPI resistance in NSCLC: targeting TAM receptors to modulate the tumor microenvironment and future prospects | |
| Lu et al. | Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs | |
| Procaccio et al. | Immunotherapy in gastrointestinal cancers | |
| Harris et al. | Immuno-oncology combinations: raising the tail of the survival curve | |
| Tartour et al. | Lung cancer: potential targets for immunotherapy | |
| CY1124791T1 (el) | Μορια δεσμευσης ειδικα για cd73 και χρησεις αυτων | |
| JP2016539096A5 (https=) | ||
| JP2018515474A5 (https=) | ||
| JP2021512914A5 (https=) | ||
| RU2014134923A (ru) | Антагонисты alk1 и их применение в лечении почечно-клеточного рака | |
| JP2016187356A5 (https=) | ||
| Sun et al. | Immunotherapy in human colorectal cancer: challenges and prospective | |
| MX2021002190A (es) | Estrategia de dosificacion que mitiga el sindrome de liberacion de citoquinas para los anticuerpos biespecificos cd3/cd20. | |
| JP2018501197A5 (https=) | ||
| JP2016532693A5 (https=) | ||
| Duarte et al. | Gastric cancer: basic aspects | |
| JP2017506217A5 (https=) | ||
| JOP20190248A1 (ar) | بروتينات ربط مولد ضد trem2 واستخداماته | |
| PH12012502193A1 (en) | Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies | |
| JP2016537383A5 (https=) | ||
| JP2016500251A5 (https=) | ||
| EP2579895A4 (en) | ANTI-VEGF ANTIBODIES AND USES THEREOF | |
| JP2017537972A5 (https=) |