JP2015505244A5 - - Google Patents

Download PDF

Info

Publication number
JP2015505244A5
JP2015505244A5 JP2014549503A JP2014549503A JP2015505244A5 JP 2015505244 A5 JP2015505244 A5 JP 2015505244A5 JP 2014549503 A JP2014549503 A JP 2014549503A JP 2014549503 A JP2014549503 A JP 2014549503A JP 2015505244 A5 JP2015505244 A5 JP 2015505244A5
Authority
JP
Japan
Prior art keywords
antibody
amino acid
peptide
antigen
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014549503A
Other languages
English (en)
Japanese (ja)
Other versions
JP6242808B2 (ja
JP2015505244A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2013/050024 external-priority patent/WO2013098419A1/en
Publication of JP2015505244A publication Critical patent/JP2015505244A/ja
Publication of JP2015505244A5 publication Critical patent/JP2015505244A5/ja
Application granted granted Critical
Publication of JP6242808B2 publication Critical patent/JP6242808B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014549503A 2011-12-28 2013-01-02 所望の特異性を有するモノクローナル自己抗体を提供する方法 Expired - Fee Related JP6242808B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161580837P 2011-12-28 2011-12-28
EP11195952.4 2011-12-28
EP11195952 2011-12-28
US61/580,837 2011-12-28
PCT/EP2013/050024 WO2013098419A1 (en) 2011-12-28 2013-01-02 Method of providing monoclonal auto-antibodies with desired specificity

Publications (3)

Publication Number Publication Date
JP2015505244A JP2015505244A (ja) 2015-02-19
JP2015505244A5 true JP2015505244A5 (OSRAM) 2016-01-21
JP6242808B2 JP6242808B2 (ja) 2017-12-06

Family

ID=48696366

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014549503A Expired - Fee Related JP6242808B2 (ja) 2011-12-28 2013-01-02 所望の特異性を有するモノクローナル自己抗体を提供する方法

Country Status (12)

Country Link
US (2) US9475872B2 (OSRAM)
EP (3) EP2797951B1 (OSRAM)
JP (1) JP6242808B2 (OSRAM)
AU (3) AU2013206788B2 (OSRAM)
CA (2) CA2861695C (OSRAM)
DK (1) DK2797951T3 (OSRAM)
ES (2) ES2964168T3 (OSRAM)
HU (1) HUE037186T2 (OSRAM)
PL (2) PL2797951T3 (OSRAM)
PT (1) PT2797951T (OSRAM)
SI (1) SI2797952T1 (OSRAM)
WO (2) WO2013098419A1 (OSRAM)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10131709B2 (en) 2011-12-28 2018-11-20 Immunoqure Ag Nucleic acid molecules encoding monoclonal antibodies specific for IL-22
EP2626367A1 (en) * 2012-02-10 2013-08-14 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method for obtaining three-dimensional actin structures and uses thereof
WO2014093786A1 (en) * 2012-12-14 2014-06-19 Abbvie, Inc. Methods for increasing the efficiency of hybridoma generation
WO2015001047A1 (en) 2013-07-03 2015-01-08 Immunoqure Ag Method of providing anti-human cytokine antibodies for pharmaceutical use
AU2014286131C1 (en) 2013-07-03 2020-02-13 Immunoqure Ag Human anti-IFN-alpha antibodies
WO2015001010A1 (en) * 2013-07-03 2015-01-08 Immunoqure Ag Human anti-il-32 antibodies
EP2863231A1 (en) * 2013-10-17 2015-04-22 Institut D'Investigaciones Biomédiques August Pi i Sunyer Diagnostic method for detecting a GABA(A) related autoimmune disease and related subject-matter
KR20170027795A (ko) * 2014-07-03 2017-03-10 이뮤노큐어 아게 항-사이토카인 항체의 동정을 위한 인간-유래 항-인간 il-20 항체 및 검정
EP3217175B1 (en) * 2014-11-07 2020-12-23 Fujikura Kasei Co., Ltd. Arteriosclerosis detection method using deoxyhypusine synthase gene as indicator
US10508149B2 (en) 2015-04-01 2019-12-17 Anaptysbio, Inc. Antibodies directed against T cell immunoglobulin and mucin protein 3 (TIM-3)
MX2017013080A (es) 2015-04-15 2018-02-09 Anaptysbio Inc Anticuerpos dirigidos contra receptor de interleucina 36 (il-36r).
US20180244802A1 (en) * 2015-08-17 2018-08-30 Deutsches Zentrum Fur Neurodegenerative Erkrankungen E.V. (Dzne) Antibody or antibody fragment of non-ig scaffold binding to a binding region of an anti-n-methyl-d-aspartate (nmda) receptor antibody
FR3050535B1 (fr) 2016-04-25 2020-11-13 Hospices Civils Lyon Anticorps anti il17
WO2018017996A1 (en) * 2016-07-22 2018-01-25 University Of Washington Identification and production of high affinity igm antibodies and derivatives thereof
MX2019005116A (es) 2016-11-01 2019-11-12 Anaptysbio Inc Anticuerpos dirigidos contra la proteina de inmunoglobulina de linfocitos t y de mucina 3 (tim-3).
US11926665B2 (en) 2017-01-09 2024-03-12 Tesaro, Inc. Methods of treating cancer with anti-TIM-3 antibodies
US11619832B2 (en) 2018-03-08 2023-04-04 Coopervision International Limited Identification of contact lens wearers predisposed to contact lens discomfort
CA3125474A1 (en) 2019-01-07 2020-07-16 Shattuck Labs, Inc. Heterodimeric proteins for modulating gamma delta t cells
US11098093B2 (en) 2019-01-07 2021-08-24 Shattuck Labs, Inc. Heterodimeric proteins for modulating gamma delta T cells
WO2021250323A1 (en) * 2020-06-09 2021-12-16 Helsingin Yliopisto Anti-cox-2 autoantibody as a diagnostic marker, and methods, kits and uses related thereto
EP4305190A4 (en) 2021-03-11 2025-03-26 Iggenix, Inc. METHODS AND SYSTEMS FOR PREDICTING AN ALLERGIC REACTION
WO2023213400A1 (en) * 2022-05-05 2023-11-09 Institute For Research In Biomedicine Antibodies against chemokines, method for identifying said antibodies and uses thereof
CN115724983B (zh) * 2022-10-10 2023-09-19 宝船生物医药科技(上海)有限公司 一种针对抗csf1r单克隆抗体的抗独特型抗体及其应用
WO2025158009A1 (en) 2024-01-26 2025-07-31 Almirall S.A. Bispecific molecules and methods of treatment using the same

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
ATE120761T1 (de) 1987-05-21 1995-04-15 Creative Biomolecules Inc Multifunktionelle proteine mit vorbestimmter zielsetzung.
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
JPH02503867A (ja) 1988-04-15 1990-11-15 プロテイン デザイン ラブズ インコーポレーテッド Il‐2レセプター特異的キメラ抗体
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
ATE356869T1 (de) 1990-01-12 2007-04-15 Amgen Fremont Inc Bildung von xenogenen antikörpern
GB9020282D0 (en) 1990-09-17 1990-10-31 Gorman Scott D Altered antibodies and their preparation
DK9091D0 (da) 1991-01-18 1991-01-18 Novo Nordisk As Fremgangsmaade til fremstilling af antistoffer
DE4130786A1 (de) * 1991-09-16 1993-03-18 Symbiotec Gmbh Peptide zur herstellung von mitteln zur diagnose und therapie von systemischen lupus
JP2006008694A (ja) * 1991-09-16 2006-01-12 Symbiotec Ges Zur Forschung & Entwicklung Au F Dem Gebiet Der Biotechnologie Mbh 全身性エリテマトーデスの診断、治療製剤製造用ペプチド
EP2224006A1 (en) 1991-12-02 2010-09-01 MedImmune Limited Production of anti-self antibodies from antibody segment repertoires and displayed on phage
SG48760A1 (en) 1992-07-24 2003-03-18 Abgenix Inc Generation of xenogenetic antibodies
EP0903408A3 (en) 1992-08-21 2005-11-02 Biogen, Inc. Tat-derived transport polypeptide
US6309636B1 (en) * 1995-09-14 2001-10-30 Cancer Research Institute Of Contra Costa Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides
ATE390933T1 (de) 1995-04-27 2008-04-15 Amgen Fremont Inc Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8
AU2466895A (en) 1995-04-28 1996-11-18 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0776906A3 (de) * 1995-10-19 1998-02-25 Imtec Immundiagnostika Gmbh Peptide des Antigens Sm-D und ihre Verwendung, insbesondere für die Diagnostik des SLE
US6590079B2 (en) 1997-01-30 2003-07-08 Ixsys, Incorporated Anti-αvβ3 recombinant human antibodies, nucleic acids encoding same
FI973762A0 (fi) 1997-09-23 1997-09-23 Krohn Kai Ny gen
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US6531580B1 (en) 1999-06-24 2003-03-11 Ixsys, Inc. Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
US6849425B1 (en) 1999-10-14 2005-02-01 Ixsys, Inc. Methods of optimizing antibody variable region binding affinity
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
US20030044870A1 (en) 2001-07-13 2003-03-06 Peter Sehr Generic capture elisa using recombinant fusion proteins for detecting antibodies in biological samples
JP4489582B2 (ja) * 2002-05-28 2010-06-23 オムリクス・バイオフアーマシユーチカルズ・インコーポレーテツド 抗イディオタイプ抗体を得る方法
US20040101909A1 (en) 2002-08-20 2004-05-27 Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 Purification of polyreactive autoantibodies and uses thereof
EP1597280B2 (en) 2003-02-26 2016-08-24 Institute for Research in Biomedicine Monoclonal antibody production by ebv transformation of b cells
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
US7158410B2 (en) 2004-08-27 2007-01-02 Micron Technology, Inc. Integrated DRAM-NVRAM multi-level memory
US8338172B2 (en) 2005-12-16 2012-12-25 Ribovax Biotechnologies S.A. Methods for obtaining immortalized antibody secreting cells
WO2007106769A2 (en) * 2006-03-10 2007-09-20 Zymogenetics, Inc. Antibodies that bind both il-17a and il-17f and methods of using the same
TW200815469A (en) 2006-06-23 2008-04-01 Astrazeneca Ab Compounds
JP4059404B2 (ja) * 2006-09-22 2008-03-12 栄研化学株式会社 甲状腺機能を刺激する活性を持つ抗体
PL2099826T3 (pl) 2007-01-05 2014-04-30 Univ Zuerich Przeciwciało przeciwko beta-amyloidowi i jego zastosowania
NZ579520A (en) 2007-03-13 2012-06-29 Univ Zuerich Monoclonal human tumor-specific antibody that bnids to ny-eso-1
JP5808536B2 (ja) * 2007-10-25 2015-11-10 トレリス バイオサイエンス、インク. 抗rsvgタンパク質抗体
GB0807413D0 (en) * 2008-04-23 2008-05-28 Ucb Pharma Sa Biological products
SG190626A1 (en) * 2008-05-05 2013-06-28 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
WO2010003529A1 (en) 2008-06-16 2010-01-14 University Of Zurich Method of providing immunoglobulin secreting b lymphocytes and human antibodies
PT2370466E (pt) 2008-12-19 2015-09-21 Univ Zuerich Autoanticorpos humanos anti-alfa-sinucleína
CN102458437B (zh) * 2009-05-05 2015-06-10 诺维莫尼公司 抗il-17f抗体及其使用方法
EP2258727A1 (en) 2009-05-27 2010-12-08 Wezen Biopharmaceuticals S.r.l. A Socio Unico Immunoglobulin preparation for the treatment of autoimmune diseases and immune system disorders

Similar Documents

Publication Publication Date Title
JP2015505244A5 (OSRAM)
US12410256B2 (en) Antibodies that specifically bind to TL1a and methods of treating gastrointestinal or lung diseases
RU2474588C2 (ru) Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения
CN102307901B (zh) 抗il-1r1结合成员
RU2016136639A (ru) Антитела против эотаксина 2, которые распознают дополнительные связывающие CCR3 хемокины
US9127057B2 (en) Anti-IL-23 heterodimer specific antibodies
RU2018111508A (ru) Анти-LAG-3 антитела
RU2011149334A (ru) Анти-il-17f антитела и способы их применения
RU2013153592A (ru) Анти-mif антитела
JP2018121657A5 (OSRAM)
AU2015287227B2 (en) Immune-stimulating monoclonal antibodies against human interleukin-2
Schaller et al. The splenic autoimmune response to ADAMTS13 in thrombotic thrombocytopenic purpura contains recurrent antigen-binding CDR3 motifs
JP2015530971A5 (OSRAM)
SI2481753T1 (en) Anti-IL-17 antibodies
RU2017107773A (ru) Антитела, специфичные к ммр9
JP2016503293A5 (OSRAM)
JP2012524524A5 (OSRAM)
CN101851291A (zh) 一种抗人baff单克隆抗体的重链和轻链可变区
CN113646330A (zh) 工程化cd25多肽及其用途
WO2018050028A1 (zh) 一种能够特异性地结合il-17a的抗体及其功能片段
US11428697B2 (en) Compositions and methods for treating age-related diabetes and related disorders
Du et al. Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients
TW201625947A (zh) 測定fviii的反應性之方法
Tsuboi et al. Generation and functional analysis of monoclonal antibodies against the second extracellular loop of human M3 muscarinic acetylcholine receptor
CN116554323A (zh) 人源化抗il21抗体的开发和应用