JP2015504874A5 - - Google Patents
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- Publication number
- JP2015504874A5 JP2015504874A5 JP2014547975A JP2014547975A JP2015504874A5 JP 2015504874 A5 JP2015504874 A5 JP 2015504874A5 JP 2014547975 A JP2014547975 A JP 2014547975A JP 2014547975 A JP2014547975 A JP 2014547975A JP 2015504874 A5 JP2015504874 A5 JP 2015504874A5
- Authority
- JP
- Japan
- Prior art keywords
- thiazole
- carboxylate
- ethyl
- oxy
- fluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11194365.0 | 2011-12-19 | ||
| EP11194365.0A EP2606888A1 (en) | 2011-12-19 | 2011-12-19 | Trpm8 antagonists |
| EP12178327.8 | 2012-07-27 | ||
| EP12178327 | 2012-07-27 | ||
| PCT/EP2012/076147 WO2013092711A1 (en) | 2011-12-19 | 2012-12-19 | Trpm8 antagonists |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017119493A Division JP2017197564A (ja) | 2011-12-19 | 2017-06-19 | Ｔｒｐｍ８拮抗薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015504874A JP2015504874A (ja) | 2015-02-16 |
| JP2015504874A5 true JP2015504874A5 (OSRAM) | 2015-10-29 |
| JP6238906B2 JP6238906B2 (ja) | 2017-11-29 |
Family
ID=47520061
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547975A Active JP6238906B2 (ja) | 2011-12-19 | 2012-12-19 | Ｔｒｐｍ８拮抗薬 |
| JP2017119493A Withdrawn JP2017197564A (ja) | 2011-12-19 | 2017-06-19 | Ｔｒｐｍ８拮抗薬 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017119493A Withdrawn JP2017197564A (ja) | 2011-12-19 | 2017-06-19 | Ｔｒｐｍ８拮抗薬 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9585875B2 (OSRAM) |
| EP (1) | EP2793883B1 (OSRAM) |
| JP (2) | JP6238906B2 (OSRAM) |
| KR (1) | KR102000319B1 (OSRAM) |
| CN (1) | CN104220069B (OSRAM) |
| AU (1) | AU2012357747B2 (OSRAM) |
| CY (1) | CY1120403T1 (OSRAM) |
| DK (1) | DK2793883T3 (OSRAM) |
| EA (1) | EA025356B1 (OSRAM) |
| ES (1) | ES2676884T3 (OSRAM) |
| HR (1) | HRP20181086T1 (OSRAM) |
| HU (1) | HUE038407T2 (OSRAM) |
| LT (1) | LT2793883T (OSRAM) |
| ME (1) | ME03038B (OSRAM) |
| PL (1) | PL2793883T3 (OSRAM) |
| PT (1) | PT2793883T (OSRAM) |
| RS (1) | RS57389B1 (OSRAM) |
| SI (1) | SI2793883T1 (OSRAM) |
| SM (1) | SMT201800351T1 (OSRAM) |
| TR (1) | TR201808861T4 (OSRAM) |
| WO (1) | WO2013092711A1 (OSRAM) |
| ZA (1) | ZA201404499B (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2481727A1 (en) * | 2011-01-28 | 2012-08-01 | Dompe S.p.A. | TRPM8 receptor antagonists |
| AU2012357747B2 (en) | 2011-12-19 | 2017-09-07 | Dompe' Farmaceutici S.P.A. | TRPM8 antagonists |
| US20160166570A1 (en) * | 2013-05-24 | 2016-06-16 | Nestec S.A. | Treatment or prevention of non-inflammatory neuronal damage from brain trauma and strokes using menthol, linalool and/or icilin |
| CN106715424B (zh) | 2014-06-05 | 2020-07-14 | 拜耳作物科学股份公司 | 作为农药的双环化合物 |
| ME03399B (me) * | 2014-06-23 | 2020-01-20 | Dompe Farm Spa | DERIVATI 2-ARIL-4-HIDROKSI-1,3-TIAZOLA KORISNI KAO INHIBITORI TRPM8 U LEĆENJU NEURALGIJE, BOLA, COPD l ASTME |
| MX389514B (es) * | 2015-10-01 | 2025-03-20 | Firmenich Incorporated | Compuestos útiles como moduladores de canal receptor 8 de potencial transitorio de melastatina (trpm8). |
| EP3184524A1 (en) * | 2015-12-21 | 2017-06-28 | Dompé farmaceutici S.p.A. | 4-hydroxy-2-phenyl-1,3-thiazol-5-yl methanone derivatives as trpm8 antagonists |
| CN113398124A (zh) | 2016-06-13 | 2021-09-17 | 田边三菱制药株式会社 | 用于治疗或预防血管舒缩症状的组合物 |
| WO2018117166A1 (ja) * | 2016-12-21 | 2018-06-28 | キッセイ薬品工業株式会社 | チアゾール誘導体、またはその薬理学的に許容される塩 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2713573A1 (de) | 1977-03-28 | 1978-10-05 | Basf Ag | 4,5-disubstituierte thiazole und verfahren zu ihrer herstellung |
| JPS59220687A (ja) * | 1983-05-30 | 1984-12-12 | 株式会社日立製作所 | 直接サイクル型軽水原子炉一次冷却系の腐食環境抑制設備 |
| ES2092580T3 (es) * | 1990-11-30 | 1996-12-01 | Teijin Ltd | Derivado de 2-ariltiazol y composicion farmaceutica que contiene el mismo. |
| DE60221627D1 (de) * | 2001-12-21 | 2007-09-20 | Virochem Pharma Inc | Thiazolderivate und ihre Verwendung zur Behandlung oder Vorbeugung von Infektionen durch Flaviviren |
| EP1802600A1 (en) | 2004-10-13 | 2007-07-04 | Bayer HealthCare AG | Substituted 4-benzyloxy-phenylmethylamide derivatives as cold menthol receptor-1 (cmr-1) antagonits for the treatment of urological disorders |
| WO2007017094A1 (en) | 2005-08-04 | 2007-02-15 | Bayer Healthcare Ag | Substituted benzyloxy-phenylmethylcarbamate derivatives |
| WO2007017093A1 (en) | 2005-08-04 | 2007-02-15 | Bayer Healthcare Ag | Substituted 2-benzyloxy-benzoic acid amide derivatives |
| WO2007017092A1 (en) | 2005-08-04 | 2007-02-15 | Bayer Healthcare Ag | Substituted 4-benzyloxy-benzoic acid amide derivatives |
| WO2007080109A1 (en) | 2006-01-16 | 2007-07-19 | Bayer Healthcare Ag | Substituded benzyloxy-phenylmethylurea derivatives |
| WO2007089031A1 (en) | 2006-02-01 | 2007-08-09 | Takeda Pharmaceutical Company Limited | Piperidine derivatives as tachykinin receptor antagonists |
| US7897781B2 (en) | 2006-05-10 | 2011-03-01 | Janssen Pharmaceutica Nv | Cold menthol receptor-1 antagonists |
| MY153971A (en) | 2007-07-18 | 2015-04-30 | Janssen Pharmaceutica Nv | Sulfonamides as trpm8 modulators |
| CA2747662A1 (en) * | 2008-12-18 | 2010-07-15 | Janssen Pharmaceutica Nv | Sulfonamides as trpm8 modulators |
| WO2010103381A1 (en) | 2009-03-13 | 2010-09-16 | Glenmark Pharmaceuticals S.A. | Spirocyclic piperidine derivatives as trpm 8 modulators |
| CN102427810A (zh) * | 2009-05-01 | 2012-04-25 | 拉夸里亚创药株式会社 | 作为trpm8拮抗剂的氨磺酰基苯甲酸衍生物 |
| WO2012036233A1 (ja) | 2010-09-17 | 2012-03-22 | 塩野義製薬株式会社 | メラニン凝集ホルモン受容体アンタゴニスト活性を有する縮合へテロ環誘導体 |
| AU2012357747B2 (en) | 2011-12-19 | 2017-09-07 | Dompe' Farmaceutici S.P.A. | TRPM8 antagonists |
-
2012
- 2012-12-19 AU AU2012357747A patent/AU2012357747B2/en active Active
- 2012-12-19 HU HUE12812229A patent/HUE038407T2/hu unknown
- 2012-12-19 DK DK12812229.8T patent/DK2793883T3/en active
- 2012-12-19 RS RS20180793A patent/RS57389B1/sr unknown
- 2012-12-19 PL PL12812229T patent/PL2793883T3/pl unknown
- 2012-12-19 TR TR2018/08861T patent/TR201808861T4/tr unknown
- 2012-12-19 JP JP2014547975A patent/JP6238906B2/ja active Active
- 2012-12-19 LT LTEP12812229.8T patent/LT2793883T/lt unknown
- 2012-12-19 ES ES12812229.8T patent/ES2676884T3/es active Active
- 2012-12-19 ME MEP-2018-177A patent/ME03038B/me unknown
- 2012-12-19 EA EA201491213A patent/EA025356B1/ru unknown
- 2012-12-19 HR HRP20181086TT patent/HRP20181086T1/hr unknown
- 2012-12-19 SM SM20180351T patent/SMT201800351T1/it unknown
- 2012-12-19 KR KR1020147019697A patent/KR102000319B1/ko active Active
- 2012-12-19 US US14/366,796 patent/US9585875B2/en active Active
- 2012-12-19 EP EP12812229.8A patent/EP2793883B1/en active Active
- 2012-12-19 CN CN201280069993.7A patent/CN104220069B/zh active Active
- 2012-12-19 WO PCT/EP2012/076147 patent/WO2013092711A1/en not_active Ceased
- 2012-12-19 SI SI201231328T patent/SI2793883T1/en unknown
- 2012-12-19 PT PT128122298T patent/PT2793883T/pt unknown
-
2014
- 2014-06-19 ZA ZA2014/04499A patent/ZA201404499B/en unknown
-
2017
- 2017-01-25 US US15/414,803 patent/US9856246B2/en active Active
- 2017-06-19 JP JP2017119493A patent/JP2017197564A/ja not_active Withdrawn
-
2018
- 2018-07-10 CY CY20181100717T patent/CY1120403T1/el unknown
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