JP2015227805A - 液中粒子検出装置及び液中粒子の検出方法 - Google Patents

液中粒子検出装置及び液中粒子の検出方法 Download PDF

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Publication number
JP2015227805A
JP2015227805A JP2014113354A JP2014113354A JP2015227805A JP 2015227805 A JP2015227805 A JP 2015227805A JP 2014113354 A JP2014113354 A JP 2014113354A JP 2014113354 A JP2014113354 A JP 2014113354A JP 2015227805 A JP2015227805 A JP 2015227805A
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JP
Japan
Prior art keywords
liquid
flow cell
light
scattered light
intensity
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Pending
Application number
JP2014113354A
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English (en)
Japanese (ja)
Inventor
太輔 小原
Tasuke Obara
太輔 小原
雅 古谷
Masa Furuya
雅 古谷
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Azbil Corp
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Azbil Corp
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Publication date
Application filed by Azbil Corp filed Critical Azbil Corp
Priority to JP2014113354A priority Critical patent/JP2015227805A/ja
Priority to EP15169307.4A priority patent/EP2950105B1/fr
Priority to US14/723,543 priority patent/US20150346091A1/en
Priority to CN201510281734.6A priority patent/CN105136673B/zh
Publication of JP2015227805A publication Critical patent/JP2015227805A/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00623—Quality control of instruments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1026—Recognising analyser failures, e.g. bubbles; Quality control for particle analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4702—Global scatter; Total scatter, excluding reflections
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N2021/4764—Special kinds of physical applications
    • G01N2021/4769—Fluid samples, e.g. slurries, granulates; Compressible powdery of fibrous samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G01N2201/0612—Laser diodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Dispersion Chemistry (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2014113354A 2014-05-30 2014-05-30 液中粒子検出装置及び液中粒子の検出方法 Pending JP2015227805A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2014113354A JP2015227805A (ja) 2014-05-30 2014-05-30 液中粒子検出装置及び液中粒子の検出方法
EP15169307.4A EP2950105B1 (fr) 2014-05-30 2015-05-27 Dispositif et procédé de détection de particules dans un liquide
US14/723,543 US20150346091A1 (en) 2014-05-30 2015-05-28 Device for detecting particles in a liquid and method for detecting particles in a liquid
CN201510281734.6A CN105136673B (zh) 2014-05-30 2015-05-28 液体中粒子检测装置及液体中粒子的检测方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2014113354A JP2015227805A (ja) 2014-05-30 2014-05-30 液中粒子検出装置及び液中粒子の検出方法

Publications (1)

Publication Number Publication Date
JP2015227805A true JP2015227805A (ja) 2015-12-17

Family

ID=53199888

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014113354A Pending JP2015227805A (ja) 2014-05-30 2014-05-30 液中粒子検出装置及び液中粒子の検出方法

Country Status (4)

Country Link
US (1) US20150346091A1 (fr)
EP (1) EP2950105B1 (fr)
JP (1) JP2015227805A (fr)
CN (1) CN105136673B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017199615A1 (fr) * 2016-05-17 2017-11-23 アズビル株式会社 Dispositif de détection de particules et procédé d'inspection de dispositif de détection de particules
JP2017207336A (ja) * 2016-05-17 2017-11-24 アズビル株式会社 粒子検出装置及び粒子検出装置の検査方法
WO2019045488A1 (fr) * 2017-08-31 2019-03-07 서울바이오시스 주식회사 Détecteur
WO2019187754A1 (fr) * 2018-03-30 2019-10-03 シスメックス株式会社 Cytomètre de flux et procédé pour détecter des particules

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6325423B2 (ja) * 2014-10-10 2018-05-16 アズビル株式会社 液中蛍光検出装置及び液中の蛍光の検出方法
CN105510297A (zh) * 2015-12-29 2016-04-20 北京华泰诺安探测技术有限公司 拉曼荧光光谱测试系统及其光信号收集器
US10648909B2 (en) * 2017-05-25 2020-05-12 Abbott Laboratories Methods and systems for assessing flow cell cleanliness

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JPS63195548A (ja) * 1987-02-07 1988-08-12 Canon Inc 粒子解析装置
JPH06323982A (ja) * 1993-05-11 1994-11-25 Sumitomo Chem Co Ltd 微粒子計測方法およびそのための装置
JPH08240520A (ja) * 1995-03-06 1996-09-17 Toa Medical Electronics Co Ltd 尿中赤血球の鑑別装置
US20070257215A1 (en) * 2005-05-06 2007-11-08 Collin Rich Flow cytometry system with bubble detection
JP2008039735A (ja) * 2006-08-10 2008-02-21 Matsushita Electric Ind Co Ltd 粒子計測装置
JP2010513847A (ja) * 2006-06-27 2010-04-30 バイオヴィジラント システムズ インコーポレイテッド 粒度および蛍光の同時測定による病原体検出
JP2011047911A (ja) * 2009-08-28 2011-03-10 Sysmex Corp 自動分析装置

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JPS62188942A (ja) * 1986-02-14 1987-08-18 Shimadzu Corp ドリフト補正方法
US5467189A (en) * 1993-01-22 1995-11-14 Venturedyne, Ltd. Improved particle sensor and method for assaying a particle
CA2125546A1 (fr) * 1993-08-13 1995-02-14 David Kleinschmitt Methode et appareil pour detecter une interface entre liquides et gaz
JP3436539B2 (ja) * 1993-09-27 2003-08-11 ヴェンチュアダイン，リミテッド 粒子分析のための改良型粒子センサ及び方法
JP3328032B2 (ja) * 1993-11-04 2002-09-24 シスメックス株式会社 粒子分析装置
US5539386A (en) * 1994-03-07 1996-07-23 J-Kem Electronics, Inc. Sensor for detecting air/liquid transitions in a transparent tubing
JPH09113440A (ja) * 1995-10-24 1997-05-02 Meidensha Corp 光学式濃度測定装置
JP3265361B2 (ja) 1999-06-23 2002-03-11 独立行政法人産業技術総合研究所 液中粒子計測装置およびその方法
JP3263729B2 (ja) 1999-09-03 2002-03-11 独立行政法人産業技術総合研究所 液中粒子計測装置およびその方法
JP3962306B2 (ja) 2002-09-25 2007-08-22 株式会社堀場製作所 粒径分布測定方法および装置
US6936828B2 (en) * 2003-02-14 2005-08-30 Honeywell International Inc. Particle detection system and method
WO2005001436A1 (fr) * 2003-06-26 2005-01-06 The Secretary Of State For Defence Ameliorations apportees a des analyseurs de particules portees par un fluide
CN101479592B (zh) * 2006-06-27 2013-05-22 百维吉伦特系统有限公司 通过同时尺寸/荧光测量来进行病原体检测
CN101939632B (zh) * 2008-02-07 2013-05-01 三井造船株式会社 荧光检测装置和荧光检测方法
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JPS63195548A (ja) * 1987-02-07 1988-08-12 Canon Inc 粒子解析装置
JPH06323982A (ja) * 1993-05-11 1994-11-25 Sumitomo Chem Co Ltd 微粒子計測方法およびそのための装置
JPH08240520A (ja) * 1995-03-06 1996-09-17 Toa Medical Electronics Co Ltd 尿中赤血球の鑑別装置
US20070257215A1 (en) * 2005-05-06 2007-11-08 Collin Rich Flow cytometry system with bubble detection
JP2010513847A (ja) * 2006-06-27 2010-04-30 バイオヴィジラント システムズ インコーポレイテッド 粒度および蛍光の同時測定による病原体検出
JP2008039735A (ja) * 2006-08-10 2008-02-21 Matsushita Electric Ind Co Ltd 粒子計測装置
JP2011047911A (ja) * 2009-08-28 2011-03-10 Sysmex Corp 自動分析装置

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017199615A1 (fr) * 2016-05-17 2017-11-23 アズビル株式会社 Dispositif de détection de particules et procédé d'inspection de dispositif de détection de particules
JP2017207336A (ja) * 2016-05-17 2017-11-24 アズビル株式会社 粒子検出装置及び粒子検出装置の検査方法
JP2017207337A (ja) * 2016-05-17 2017-11-24 アズビル株式会社 粒子検出装置及び粒子検出装置の検査方法
US10670513B2 (en) 2016-05-17 2020-06-02 Azbil Corporation Particle detecting device and method for inspecting particle detecting device
WO2019045488A1 (fr) * 2017-08-31 2019-03-07 서울바이오시스 주식회사 Détecteur
KR20190024028A (ko) * 2017-08-31 2019-03-08 서울바이오시스 주식회사 검출기
KR102450625B1 (ko) 2017-08-31 2022-10-07 서울바이오시스 주식회사 검출기
US11467088B2 (en) 2017-08-31 2022-10-11 Seoul Viosys Co., Ltd. Detector
WO2019187754A1 (fr) * 2018-03-30 2019-10-03 シスメックス株式会社 Cytomètre de flux et procédé pour détecter des particules
JP2019178900A (ja) * 2018-03-30 2019-10-17 シスメックス株式会社 フローサイトメーター及び粒子検出方法
JP7109229B2 (ja) 2018-03-30 2022-07-29 シスメックス株式会社 フローサイトメーター及び粒子検出方法

Also Published As

Publication number Publication date
CN105136673B (zh) 2019-06-28
CN105136673A (zh) 2015-12-09
EP2950105A1 (fr) 2015-12-02
EP2950105B1 (fr) 2020-07-22
US20150346091A1 (en) 2015-12-03

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