JP2015110565A5 - - Google Patents
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- Publication number
- JP2015110565A5 JP2015110565A5 JP2014237028A JP2014237028A JP2015110565A5 JP 2015110565 A5 JP2015110565 A5 JP 2015110565A5 JP 2014237028 A JP2014237028 A JP 2014237028A JP 2014237028 A JP2014237028 A JP 2014237028A JP 2015110565 A5 JP2015110565 A5 JP 2015110565A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- water
- nanodispersion
- sterol
- docetaxel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N Docetaxel Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N Intaxel Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 229960001592 Paclitaxel Drugs 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 229960003668 docetaxel Drugs 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 150000003432 sterols Chemical class 0.000 claims 1
- 235000003702 sterols Nutrition 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 229930003347 taxol Natural products 0.000 claims 1
- 229920003169 water-soluble polymer Polymers 0.000 claims 1
Description
Claims (1)
- 水混和性非水性溶媒中に、ドセタキセルまたはパクリタキセルから選択される１種以上のタキサン誘導体、水溶性ポリマー、および、脂肪酸またはその塩とステロールまたはその塩との混合物を含む界面活性剤を含んでなる溶液であって、水性液体ビヒクルによる希釈時にナノ分散体を生じる溶液。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2527/MUM/2007 | 2007-12-24 | ||
| IN2527MU2007 | 2007-12-24 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010540226A Division JP5656643B2 (ja) | 2007-12-24 | 2008-12-23 | ナノ分散体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015110565A JP2015110565A (ja) | 2015-06-18 |
| JP2015110565A5 true JP2015110565A5 (ja) | 2016-04-21 |
| JP5937180B2 JP5937180B2 (ja) | 2016-06-22 |
Family
ID=40853553
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010540226A Active JP5656643B2 (ja) | 2007-12-24 | 2008-12-23 | ナノ分散体 |
| JP2014237028A Active JP5937180B2 (ja) | 2007-12-24 | 2014-11-21 | ナノ分散体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010540226A Active JP5656643B2 (ja) | 2007-12-24 | 2008-12-23 | ナノ分散体 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8586062B2 (ja) |
| EP (2) | EP2231144B1 (ja) |
| JP (2) | JP5656643B2 (ja) |
| KR (1) | KR101505419B1 (ja) |
| CN (1) | CN101909614B (ja) |
| AP (1) | AP2895A (ja) |
| AU (1) | AU2008346121B2 (ja) |
| BR (1) | BRPI0821514B8 (ja) |
| CA (1) | CA2710525C (ja) |
| CO (1) | CO6290681A2 (ja) |
| DK (1) | DK2231144T3 (ja) |
| EA (1) | EA016434B1 (ja) |
| ES (1) | ES2509490T3 (ja) |
| IL (1) | IL206584A0 (ja) |
| MX (1) | MX2010007076A (ja) |
| NZ (1) | NZ586343A (ja) |
| PL (1) | PL2231144T3 (ja) |
| UA (1) | UA100543C2 (ja) |
| WO (1) | WO2009087678A2 (ja) |
| ZA (1) | ZA201004450B (ja) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120050414A (ko) * | 2009-06-19 | 2012-05-18 | 썬 파마 어드밴스트 리서치 컴패니 리미티드 | 약물의 나노분산액 및 그의 제조 방법 |
| CN102038635A (zh) | 2009-10-23 | 2011-05-04 | 天津天士力集团有限公司 | 一种含有pH值调节剂的紫杉烷类药物溶液及其制备方法 |
| KR20110056042A (ko) * | 2009-11-20 | 2011-05-26 | 주식회사유한양행 | 종양세포 표적지향을 위한 나노 입자 및 이의 제조방법 |
| CA2798180A1 (en) | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| ES2385995B2 (es) * | 2011-01-10 | 2013-05-21 | Universidade De Santiago De Compostela | Nanocápsulas con cubierta polimérica |
| CN102078300B (zh) * | 2011-01-27 | 2012-01-11 | 海南美大制药有限公司 | 托拉塞米脂质体固体制剂 |
| CN102366409B (zh) * | 2011-09-14 | 2013-03-20 | 海南灵康制药有限公司 | 一种尼扎替丁脂质体固体制剂 |
| JO3685B1 (ar) * | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| BR112015022231B1 (pt) * | 2013-03-14 | 2020-11-24 | Griffith Laboratories International, Inc. | Metodo para tratamento de fungos que causam sigatoka negra em plantaqoes da familia musaceae |
| US20170099833A1 (en) * | 2014-05-30 | 2017-04-13 | Oms Investments, Inc. | Nano-sized water-based dispersion compositions and methods of making thereof |
| KR101692314B1 (ko) * | 2015-03-27 | 2017-01-03 | 주식회사 주빅 | 지용성 약물의 생분해성 고분자 내 용해 시스템: 스마트 폴리머 시스템 |
| US20160346221A1 (en) | 2015-06-01 | 2016-12-01 | Autotelic Llc | Phospholipid-coated therapeutic agent nanoparticles and related methods |
| JP2018516964A (ja) * | 2015-06-09 | 2018-06-28 | サン、ファーマ、アドバンスト、リサーチ、カンパニー、リミテッドＳｕｎ Ｐｈａｒｍａ Ａｄｖａｎｃｅｄ Ｒｅｓｅａｒｃｈ Ｃｏｍｐａｎｙ Ｌｉｍｉｔｅｄ | 局所進行性または転移性である肝内もしくは肝外胆管または胆嚢のカルシノーマに罹患する患者を治療する方法 |
| CN107551390A (zh) * | 2017-08-21 | 2018-01-09 | 常熟佳禾生物科技有限公司 | 一种用于治疗乳腺小叶增生的中药文胸贴片及其制备方法 |
| BR112020018980A2 (pt) * | 2018-03-19 | 2020-12-29 | Epicyt Pharma Ab | Composição e composição para uso |
| US11877717B2 (en) | 2019-12-17 | 2024-01-23 | Emma Ruccio | Method and apparatus for detecting scoliosis |
| US11423574B2 (en) | 2019-12-17 | 2022-08-23 | Emma Ruccio | Method and apparatus for detecting scoliosis |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6018A (en) * | 1849-01-09 | Improvement in bog-cutters | ||
| US5399363A (en) * | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| US6753006B1 (en) | 1993-02-22 | 2004-06-22 | American Bioscience, Inc. | Paclitaxel-containing formulations |
| US6537579B1 (en) | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| KR19990075621A (ko) | 1998-03-23 | 1999-10-15 | 임성주 | 경사 평판형 배양조 |
| US6017948A (en) * | 1998-10-30 | 2000-01-25 | Supergen, Inc. | Water-miscible pharmaceutical compositions |
| US6365191B1 (en) * | 1999-02-17 | 2002-04-02 | Dabur Research Foundation | Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| AU7599900A (en) * | 1999-09-23 | 2001-04-24 | Dabur Research Foundation | Formulations of paclitaxel entrapped into nanoparticles of polymeric micelles |
| TWI230616B (en) * | 2000-09-25 | 2005-04-11 | Ind Tech Res Inst | Liposome for incorporating large amounts of hydrophobic substances |
| WO2002087563A2 (en) * | 2001-05-01 | 2002-11-07 | Angiotech Pharmaceuticals Inc. | Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions |
| DE10124952A1 (de) * | 2001-05-21 | 2002-12-12 | Bayer Ag | Verfahren zur Herstellung von Nanodispersionen |
| US20040092428A1 (en) * | 2001-11-27 | 2004-05-13 | Hongming Chen | Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof |
| US6780324B2 (en) * | 2002-03-18 | 2004-08-24 | Labopharm, Inc. | Preparation of sterile stabilized nanodispersions |
| ITMI20022323A1 (it) * | 2002-10-31 | 2004-05-01 | Maria Rosa Gasco | Composizioni farmaceutiche atte al trattamento di malattie oftalmiche. |
| US7670627B2 (en) * | 2002-12-09 | 2010-03-02 | Salvona Ip Llc | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients |
| US7345093B2 (en) * | 2004-04-27 | 2008-03-18 | Formatech, Inc. | Methods of enhancing solubility of compounds |
| US20050288521A1 (en) * | 2004-06-29 | 2005-12-29 | Phytogen Life Sciences Inc. | Semi-synthetic conversion of paclitaxel to docetaxel |
| WO2006091780A2 (en) * | 2005-02-24 | 2006-08-31 | Elan Pharma International Limited | Nanoparticulate formulations of docetaxel and analogues thereof |
| JP2008543789A (ja) | 2005-06-17 | 2008-12-04 | ホスピラ オーストラリア ピーティーワイ エルティーディー | ドセタキセルの液体薬学的処方物 |
| AU2006324872B2 (en) * | 2005-10-21 | 2012-03-08 | Panacea Biotec Limited | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer |
| KR100917809B1 (ko) * | 2006-05-22 | 2009-09-18 | 에스케이케미칼주식회사 | 우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물 |
| US20100068251A1 (en) * | 2006-10-10 | 2010-03-18 | Jina Pharmaceuticals, Inc. | Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof |
-
2008
- 2008-12-23 DK DK08870171.9T patent/DK2231144T3/da active
- 2008-12-23 NZ NZ586343A patent/NZ586343A/en not_active IP Right Cessation
- 2008-12-23 MX MX2010007076A patent/MX2010007076A/es active IP Right Grant
- 2008-12-23 US US12/810,428 patent/US8586062B2/en active Active
- 2008-12-23 AU AU2008346121A patent/AU2008346121B2/en active Active
- 2008-12-23 KR KR1020107014449A patent/KR101505419B1/ko active IP Right Grant
- 2008-12-23 EA EA201070793A patent/EA016434B1/ru not_active IP Right Cessation
- 2008-12-23 ES ES08870171.9T patent/ES2509490T3/es active Active
- 2008-12-23 WO PCT/IN2008/000857 patent/WO2009087678A2/en active Application Filing
- 2008-12-23 JP JP2010540226A patent/JP5656643B2/ja active Active
- 2008-12-23 UA UAA201009239A patent/UA100543C2/ru unknown
- 2008-12-23 CN CN200880122577.2A patent/CN101909614B/zh active Active
- 2008-12-23 BR BRPI0821514A patent/BRPI0821514B8/pt active IP Right Grant
- 2008-12-23 PL PL08870171T patent/PL2231144T3/pl unknown
- 2008-12-23 CA CA2710525A patent/CA2710525C/en active Active
- 2008-12-23 AP AP2010005314A patent/AP2895A/xx active
- 2008-12-23 EP EP08870171.9A patent/EP2231144B1/en active Active
- 2008-12-23 EP EP14175007.5A patent/EP2853264A1/en not_active Withdrawn
-
2010
- 2010-06-23 ZA ZA2010/04450A patent/ZA201004450B/en unknown
- 2010-06-23 IL IL206584A patent/IL206584A0/en unknown
- 2010-07-22 CO CO10089145A patent/CO6290681A2/es not_active Application Discontinuation
-
2013
- 2013-10-03 US US14/045,250 patent/US20140030352A1/en not_active Abandoned
-
2014
- 2014-11-21 JP JP2014237028A patent/JP5937180B2/ja active Active
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