JP2015091272A5 - - Google Patents

Download PDF

Info

Publication number
JP2015091272A5
JP2015091272A5 JP2015026016A JP2015026016A JP2015091272A5 JP 2015091272 A5 JP2015091272 A5 JP 2015091272A5 JP 2015026016 A JP2015026016 A JP 2015026016A JP 2015026016 A JP2015026016 A JP 2015026016A JP 2015091272 A5 JP2015091272 A5 JP 2015091272A5
Authority
JP
Japan
Prior art keywords
cells
rpe
hes
cell
pigmented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015026016A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015091272A (ja
Filing date
Publication date
Priority claimed from US11/041,382 external-priority patent/US7794704B2/en
Application filed filed Critical
Publication of JP2015091272A publication Critical patent/JP2015091272A/ja
Publication of JP2015091272A5 publication Critical patent/JP2015091272A5/ja
Pending legal-status Critical Current

Links

JP2015026016A 2005-01-24 2015-02-13 網膜の変性疾患の処置のための改良されたモーダリティー Pending JP2015091272A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/041,382 US7794704B2 (en) 2004-01-23 2005-01-24 Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
US11/041,382 2005-01-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2011208002A Division JP2012024100A (ja) 2005-01-24 2011-09-22 網膜の変性疾患の処置のための改良されたモーダリティー

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017080926A Division JP2017131240A (ja) 2005-01-24 2017-03-28 網膜の変性疾患の処置のための改良されたモーダリティー

Publications (2)

Publication Number Publication Date
JP2015091272A JP2015091272A (ja) 2015-05-14
JP2015091272A5 true JP2015091272A5 (https=) 2016-09-08

Family

ID=36740924

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2007552111A Pending JP2008530984A (ja) 2005-01-24 2005-07-20 網膜の変性疾患の処置のための改良されたモーダリティー
JP2011208002A Withdrawn JP2012024100A (ja) 2005-01-24 2011-09-22 網膜の変性疾患の処置のための改良されたモーダリティー
JP2015026016A Pending JP2015091272A (ja) 2005-01-24 2015-02-13 網膜の変性疾患の処置のための改良されたモーダリティー
JP2017080926A Pending JP2017131240A (ja) 2005-01-24 2017-03-28 網膜の変性疾患の処置のための改良されたモーダリティー
JP2019149952A Pending JP2019205476A (ja) 2005-01-24 2019-08-19 網膜の変性疾患の処置のための改良されたモーダリティー
JP2021135753A Pending JP2021191290A (ja) 2005-01-24 2021-08-23 網膜の変性疾患の処置のための改良されたモーダリティー

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2007552111A Pending JP2008530984A (ja) 2005-01-24 2005-07-20 網膜の変性疾患の処置のための改良されたモーダリティー
JP2011208002A Withdrawn JP2012024100A (ja) 2005-01-24 2011-09-22 網膜の変性疾患の処置のための改良されたモーダリティー

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2017080926A Pending JP2017131240A (ja) 2005-01-24 2017-03-28 網膜の変性疾患の処置のための改良されたモーダリティー
JP2019149952A Pending JP2019205476A (ja) 2005-01-24 2019-08-19 網膜の変性疾患の処置のための改良されたモーダリティー
JP2021135753A Pending JP2021191290A (ja) 2005-01-24 2021-08-23 網膜の変性疾患の処置のための改良されたモーダリティー

Country Status (7)

Country Link
US (12) US7794704B2 (https=)
EP (3) EP2927314A1 (https=)
JP (6) JP2008530984A (https=)
AU (1) AU2005325753B2 (https=)
CA (1) CA2596227A1 (https=)
HK (1) HK1215960A1 (https=)
WO (1) WO2006080952A2 (https=)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
EP2929782A1 (en) 2004-01-23 2015-10-14 Ocata Therapeutics, Inc. Improved modalities for the treatment of degenerative diseases of the retina
US7838727B2 (en) 2004-11-04 2010-11-23 Advanced Cell Technology, Inc. Derivation of embryonic stem cells
US7893315B2 (en) 2004-11-04 2011-02-22 Advanced Cell Technology, Inc. Derivation of embryonic stem cells and embryo-derived cells
AU2007248412A1 (en) 2006-05-03 2007-11-15 Advanced Cell Technology, Inc. Derivation of embryonic stem cells and embryo-derived cells
US8796021B2 (en) 2007-02-23 2014-08-05 Advanced Cell Technology, Inc. Blastomere culture to produce mammalian embryonic stem cells
EP2147094B2 (en) * 2007-04-18 2018-02-21 Hadasit Medical Research Services & Development Limited Stem cell-derived retinal pigment epithelial cells
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
DK2185693T3 (da) 2007-07-31 2019-09-23 Lifescan Inc Differentiering af humane embryoniske stamceller
DK2209888T3 (da) 2007-10-12 2020-01-20 Astellas Inst For Regenerative Medicine Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler
AU2015201435B2 (en) * 2007-10-12 2017-02-02 Astellas Institute For Regenerative Medicine Improved methods of producing RPE cells and compositions of RPE cells
CA2954431C (en) 2007-11-27 2021-08-24 Lifescan, Inc. Differentiation of human embryonic stem cells to pancreatic cells
JP5733986B2 (ja) 2008-02-21 2015-06-10 ヤンセン バイオテツク，インコーポレーテツド 細胞の付着、培養、及び剥離のための方法、表面改質されたプレート、並びに組成物
US8481313B2 (en) * 2008-04-22 2013-07-09 Regenerative Research Foundation Retinal pigment epithelial stem cells
EP2942392B1 (en) 2008-06-30 2018-10-03 Janssen Biotech, Inc. Differentiation of pluripotent stem cells
US9234178B2 (en) 2008-10-31 2016-01-12 Janssen Biotech, Inc. Differentiation of human pluripotent stem cells
EP2350265B1 (en) 2008-10-31 2019-04-17 Janssen Biotech, Inc. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage
KR101774546B1 (ko) 2008-11-20 2017-09-04 얀센 바이오테크 인코포레이티드 마이크로-캐리어 상의 만능 줄기 세포 배양
KR101687344B1 (ko) 2008-11-20 2016-12-16 얀센 바이오테크 인코포레이티드 평면 기재상의 세포 부착 및 배양을 위한 방법 및 조성물
CN102482643B (zh) 2009-07-20 2016-06-29 詹森生物科技公司 人胚胎干细胞的分化
EP2470645B1 (en) 2009-08-24 2019-06-26 Wisconsin Alumni Research Foundation Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same
IL281453B (en) 2009-11-17 2022-07-01 Astellas Inst For Regenerative Medicine Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells
SG10201408552YA (en) 2009-12-23 2015-02-27 Janssen Biotech Inc Differentiation of human embryonic stem cells
US10626399B2 (en) 2010-01-28 2020-04-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating cognitive symptoms of an aging-associated impairment by modulating C-C chemokine receptor type 3 (CCR3)
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
WO2011094535A2 (en) * 2010-01-28 2011-08-04 The Board Of Trustees Of The Leland Stanford Junior University Biomarkers of aging for detection and treatment of disorders
PH12012501686A1 (en) 2010-03-01 2020-10-19 Janssen Biotech Inc Methods for purifying cells derived from pluripotent stem cells
RU2587634C2 (ru) 2010-05-12 2016-06-20 Янссен Байотек, Инк. Дифференцирование эмбриональных стволовых клеток человека
WO2012149480A2 (en) * 2011-04-29 2012-11-01 University Of Southern California Systems and methods for in vitro and in vivo imaging of cells on a substrate
EP2593117B1 (en) 2010-07-12 2019-03-20 University of Southern California Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same
WO2012012803A2 (en) 2010-07-23 2012-01-26 Advanced Cell Technology, Inc. Methods for detection of rare subpopulations of cells and highly purified compositions of cells
PL2853589T3 (pl) 2010-08-31 2018-05-30 Janssen Biotech, Inc Różnicowanie ludzkich zarodkowych komórek macierzystych
CN103154237B (zh) 2010-08-31 2016-03-16 詹森生物科技公司 多能干细胞的分化
EP3372672A1 (en) 2010-08-31 2018-09-12 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
US10478206B2 (en) 2011-04-29 2019-11-19 University Of Southern California Instruments and methods for the implantation of cell-seeded substrates
US8877489B2 (en) 2011-12-05 2014-11-04 California Institute Of Technology Ultrathin parylene-C semipermeable membranes for biomedical applications
IL287381B2 (en) * 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
SI2785359T1 (sl) 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
US9248013B2 (en) 2011-12-05 2016-02-02 California Institute Of Technology 3-Dimensional parylene scaffold cage
FI2794857T3 (fi) 2011-12-22 2026-03-25 Janssen Biotech Inc Ihmisen alkion kantasolujen erilaistaminen yksittäisiksi hormonaalisiksi insuliinipositiivisiksi soluiksi
CA2866590A1 (en) 2012-03-07 2013-09-12 Janssen Biotech, Inc. Defined media for expansion and maintenance of pluripotent stem cells
EP3450544A1 (en) 2012-06-08 2019-03-06 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into pancreatic endodrine cells
HK1208054A1 (en) 2012-07-12 2016-02-19 爱姆斯坦生物技术公司 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
BR112015015714A2 (pt) 2012-12-31 2017-07-11 Janssen Biotech Inc suspensão e aglomeração de células pluripotentes humanas para diferenciação em célu-las endócrinas pancreáticas
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
ES2837763T3 (es) 2012-12-31 2021-07-01 Janssen Biotech Inc Cultivo de células madre embrionarias humanas en la interconexión aire-líquido para la diferenciación en células endocrinas pancreáticas
DK2938723T3 (da) 2012-12-31 2023-02-20 Janssen Biotech Inc Differentiering af humane embryonale stamceller til pancreatiske endokrine celler under anvendelse af hb9-regulatorer
EP4292600A3 (en) 2013-03-15 2024-04-10 Astellas Institute for Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US11763070B2 (en) * 2013-03-15 2023-09-19 PowerNotes LLC Method and system for labeling and organizing data for summarizing and referencing content via a communication network
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
NZ720949A (en) 2013-12-09 2019-03-29 Univ Leland Stanford Junior Methods and compositions for treating aging-associated conditions
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
ES2859023T3 (es) * 2014-02-21 2021-09-30 Sumitomo Dainippon Pharma Co Ltd Agente para el tratamiento de enfermedades oculares, método de detección por ello y método para predecir la respuesta al rechazo asociado con el trasplante de células epiteliales de pigmento retinal
WO2015175307A1 (en) 2014-05-16 2015-11-19 Janssen Biotech, Inc. Use of small molecules to enhance mafa expression in pancreatic endocrine cells
CA2972575A1 (en) 2014-12-30 2016-07-07 Cell Cure Neurosciences Ltd. Rpe cell populations and methods of generating same
EP3916085A1 (en) 2014-12-30 2021-12-01 Cell Cure Neurosciences Ltd. Assessing retinal pigment epithelial cell populations
EP3108891B1 (en) * 2015-02-20 2021-01-06 Sumitomo Dainippon Pharma Co., Ltd. Eye disease treatment agent, screening method therefor, and method for predicting rejection response associated with retinal pigment epithelial cell transplant
SG10201907918VA (en) 2015-03-23 2019-10-30 Astellas Inst For Regenerative Medicine Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors
AU2016279804B2 (en) 2015-06-15 2019-03-07 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated conditions
CN108697641A (zh) 2015-08-18 2018-10-23 安斯泰来再生医药协会 临床制剂
DK3347456T3 (da) 2015-09-08 2024-02-19 Us Health Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet
AU2016318774B2 (en) 2015-09-08 2022-08-18 FUJIFILM Cellular Dynamics, Inc. MACS-based purification of stem cell-derived retinal pigment epithelium
US10947502B2 (en) 2015-10-20 2021-03-16 FUJIFILM Cellular Dynamics, Inc. Methods for directed differentiation of pluripotent stem cells to immune cells
US10420803B2 (en) 2016-04-14 2019-09-24 Janssen Biotech, Inc. Differentiation of pluripotent stem cells to intestinal midgut endoderm cells
CN107345219A (zh) * 2016-05-04 2017-11-14 上海米洋杨生物科技有限公司 一种构建验证视网膜感光细胞特异性表面蛋白的方法
SG11201909331UA (en) 2017-04-18 2019-11-28 Fujifilm Cellular Dynamics Inc Antigen-specific immune effector cells
WO2019130061A2 (en) 2017-12-29 2019-07-04 Cell Cure Neurosciences Ltd. Retinal pigment epithelium cell compositions
JP7553924B2 (ja) 2019-04-26 2024-09-19 国立研究開発法人理化学研究所 神経網膜と網膜色素上皮細胞とハイドロゲルとを含む複合体及びその製造方法
TW202130806A (zh) 2019-10-30 2021-08-16 安斯泰來再生醫藥協會 用於產生視網膜色素上皮細胞之方法
CN111979195B (zh) * 2020-09-04 2023-06-02 四川大学华西医院 糖尿病视网膜病变全视网膜体外培养模型的构建方法
CN112970666B (zh) * 2021-02-04 2023-02-03 复旦大学附属眼耳鼻喉科医院 一种简便式动物近视诱导装置及制作方法
JPWO2022191216A1 (https=) 2021-03-09 2022-09-15
EP4428227A4 (en) 2021-11-19 2025-11-12 Riken PROCESS FOR PRODUCING LEAF-SHAPED RETINAL TISSUE
CN118871141A (zh) 2022-03-16 2024-10-29 住友制药株式会社 移植用介质
EP4659755A1 (en) 2023-02-14 2025-12-10 RACTHERA Co., Ltd. Therapeutic drug for retinal pigment epithelium tears
JPWO2024204596A1 (https=) 2023-03-29 2024-10-03
CN116918764B (zh) * 2023-08-28 2025-11-28 河南省儿童医院郑州儿童医院 一种豚鼠近视模型的构建方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69329556D1 (de) 1993-04-30 2000-11-16 Photogenesis Inc Transplantation des retinalen pigmentepithels
GB9608145D0 (en) 1996-04-19 1996-06-26 British Tech Group Wound healing
US6878544B2 (en) 1996-04-19 2005-04-12 Neurotech Sa Retinal cell lines with extended life-span and their applications
US20040086494A1 (en) 1996-10-07 2004-05-06 John Constance Mary Immune privileged cells for delivery of proteins and peptides
CA2277278A1 (en) 1997-01-10 1998-07-16 Life Technologies, Inc. Embryonic stem cell serum replacement
EP1044024A1 (en) 1998-01-02 2000-10-18 Titan Pharmaceuticals, Inc. Use of pigmented retinal epithelial cells for creation of an immune privilege site
WO1999045094A1 (en) 1998-03-02 1999-09-10 Compucyte Corp. Selective cell analysis
US6667176B1 (en) * 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
MXPA02004233A (es) 1999-10-28 2004-02-17 Univ Massachusetts Produccion ginogenetica o androgenetica de celulas pluripotentes y lineas celulares, y uso de las mismas para producir celulas diferenciadas y tejidos.
AU2927501A (en) 2000-01-07 2001-07-24 Oregon Health And Science University Clonal propagation of primate offspring by embryo splitting
US6602711B1 (en) 2000-02-21 2003-08-05 Wisconsin Alumni Research Foundation Method of making embryoid bodies from primate embryonic stem cells
US6458589B1 (en) 2000-04-27 2002-10-01 Geron Corporation Hepatocyte lineage cells derived from pluripotent stem cells
CA2456008A1 (en) 2000-08-19 2002-02-28 Axordia Limited Stem cell differentiation
US6576464B2 (en) 2000-11-27 2003-06-10 Geron Corporation Methods for providing differentiated stem cells
EP1339438B1 (en) 2000-11-29 2005-10-19 Allergan Inc. Preventing transplant rejection in the eye
DE10108412B4 (de) * 2001-02-21 2006-03-09 Cevec Pharmaceuticals Gmbh Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung
EP1393066A4 (en) 2001-05-15 2006-01-25 Rappaport Family Inst For Res INSULIN-PRODUCING CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS
WO2003006950A2 (en) 2001-07-12 2003-01-23 Geron Corporation Cells of the cardiomyocyte lineage produced from human pluripotent stem cells
MXPA04005010A (es) 2001-11-26 2005-04-08 Advanced Cell Tech Inc METODO PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS METODOS PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS HUMANOS REPROGRAMADOS Y CELULAS DEL TALLO HUMANAS AUTOLOGAS E ISOGENICAS.
ATE526041T1 (de) 2001-12-11 2011-10-15 Fibrogen Inc Verfahren zur hemmung okularer vorgänge
EP1495120B1 (en) 2002-04-18 2012-10-10 Acuity Pharmaceuticals, Inc Means and methods for the specific modulation of target genes in the eye
US7422736B2 (en) * 2002-07-26 2008-09-09 Food Industry Research And Development Institute Somatic pluripotent cells
CN1720055A (zh) * 2002-10-04 2006-01-11 组织技术公司 视网膜上皮细胞在羊膜上的培养和移植
EP1565107A4 (en) 2002-11-14 2008-03-05 Ethicon Endo Surgery Inc METHOD AND DEVICES FOR DETECTING TISSUE CELLS
CA2518677A1 (en) 2003-03-03 2004-12-09 Nagaoka & Co., Ltd. Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same
EP2929782A1 (en) * 2004-01-23 2015-10-14 Ocata Therapeutics, Inc. Improved modalities for the treatment of degenerative diseases of the retina
US7794704B2 (en) * 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
US7838727B2 (en) 2004-11-04 2010-11-23 Advanced Cell Technology, Inc. Derivation of embryonic stem cells
CN101155913B (zh) 2005-02-11 2011-07-06 新加坡科技研究局 增殖干细胞的方法
KR100832592B1 (ko) 2006-08-17 2008-05-27 박현숙 폴리머 막을 이용한 줄기세포와 피더세포의 공배양방법
EP2147094B2 (en) 2007-04-18 2018-02-21 Hadasit Medical Research Services & Development Limited Stem cell-derived retinal pigment epithelial cells
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
DK2209888T3 (da) 2007-10-12 2020-01-20 Astellas Inst For Regenerative Medicine Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler
HU0700675D0 (en) 2007-10-15 2007-12-28 Mta Tamogatott Kutatohelyek Ir Method for monitoring stem cell differentiation
US20090233324A1 (en) 2008-03-11 2009-09-17 Kopf-Sill Anne R Methods for Diagnosing Cancer Using Samples Collected From A Central Vein Location or an Arterial Location
US8652123B2 (en) 2008-09-02 2014-02-18 Geoffrey C. GURTNER Methods and devices for improving the appearance of tissue
IL281453B (en) 2009-11-17 2022-07-01 Astellas Inst For Regenerative Medicine Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells
WO2012012803A2 (en) 2010-07-23 2012-01-26 Advanced Cell Technology, Inc. Methods for detection of rare subpopulations of cells and highly purified compositions of cells
ES2722207T3 (es) 2011-04-29 2019-08-08 Univ Southern California Procedimientos para la crioconservación de células epiteliales de pigmento retiniano derivadas de citoblastos crecidas sobre un sustrato polimérico
IL287381B2 (en) 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
US9850463B2 (en) 2012-02-01 2017-12-26 The Regents Of The University Of California Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation
US9458428B2 (en) 2012-06-05 2016-10-04 The Regents Of The University Of California Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells

Similar Documents

Publication Publication Date Title
JP2019205476A (ja) 網膜の変性疾患の処置のための改良されたモーダリティー
US9730962B2 (en) Modalities for the treatment of degenerative diseases of the retina
JP2015091272A5 (https=)
US20240226176A9 (en) Modalities for the treatment of degenerative diseases of the retina
US20240174978A1 (en) Modalities for the treatment of degenerative diseases of the retina
AU2021200383A1 (en) Improved modalities for the treatment of degenerative diseases of the retina
AU2012201562B2 (en) Improved modalities for the treatment of degenerative diseases of the retina