JP2014532402A5 - - Google Patents
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- Publication number
- JP2014532402A5 JP2014532402A5 JP2014537726A JP2014537726A JP2014532402A5 JP 2014532402 A5 JP2014532402 A5 JP 2014532402A5 JP 2014537726 A JP2014537726 A JP 2014537726A JP 2014537726 A JP2014537726 A JP 2014537726A JP 2014532402 A5 JP2014532402 A5 JP 2014532402A5
- Authority
- JP
- Japan
- Prior art keywords
- construct
- aadc
- viral
- item
- promoter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552581P | 2011-10-28 | 2011-10-28 | |
| GB1118636.8 | 2011-10-28 | ||
| US61/552,581 | 2011-10-28 | ||
| GBGB1118636.8A GB201118636D0 (en) | 2011-10-28 | 2011-10-28 | Nucleotide sequence |
| PCT/GB2012/052668 WO2013061076A1 (en) | 2011-10-28 | 2012-10-26 | Construct |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018027852A Division JP6698114B2 (ja) | 2011-10-28 | 2018-02-20 | 構築物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014532402A JP2014532402A (ja) | 2014-12-08 |
| JP2014532402A5 true JP2014532402A5 (https=) | 2015-11-12 |
| JP6296987B2 JP6296987B2 (ja) | 2018-03-20 |
Family
ID=45373567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014537726A Active JP6296987B2 (ja) | 2011-10-28 | 2012-10-26 | 構築物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11279954B2 (https=) |
| EP (2) | EP2771471B1 (https=) |
| JP (1) | JP6296987B2 (https=) |
| CN (2) | CN107523581B (https=) |
| AU (1) | AU2012328166B2 (https=) |
| CA (2) | CA2849241C (https=) |
| DK (2) | DK2771471T3 (https=) |
| ES (2) | ES2628419T3 (https=) |
| GB (1) | GB201118636D0 (https=) |
| PL (2) | PL2771471T3 (https=) |
| WO (1) | WO2013061076A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201322798D0 (en) | 2013-12-20 | 2014-02-05 | Oxford Biomedica Ltd | Production system |
| SG11201703148TA (en) | 2014-11-05 | 2017-05-30 | Voyager Therapeutics Inc | Aadc polynucleotides for the treatment of parkinson's disease |
| KR20180034467A (ko) * | 2015-08-03 | 2018-04-04 | 마이오도파 리미티드 | L-dopa의 전신 합성 및 조절 |
| GB2562774A (en) * | 2017-05-25 | 2018-11-28 | Mcdonald Michael | Genetic construct |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| SG11202011296VA (en) | 2018-05-15 | 2020-12-30 | Voyager Therapeutics Inc | Compositions and methods for the treatment of parkinson's disease |
| CN108841868A (zh) * | 2018-05-31 | 2018-11-20 | 康霖生物科技（杭州）有限公司 | 一种用于中枢神经系统疾病治疗的基因序列构建体 |
| US12281321B2 (en) | 2018-09-28 | 2025-04-22 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| US20220175962A1 (en) * | 2019-03-10 | 2022-06-09 | Sio Gene Therapies Inc. | Gene therapy compositions and methods for treating parkinson's disease |
| CN109971729B (zh) * | 2019-04-19 | 2021-07-16 | 上海信致医药科技有限公司 | 一种酶组合物 |
| GB2587319A (en) | 2019-08-12 | 2021-03-31 | Healing Genes Llc | Genetic construct |
| CN118360338A (zh) * | 2020-03-13 | 2024-07-19 | 康霖生物科技（杭州）有限公司 | 一种核酸构建体 |
| GB2601752A (en) | 2020-12-08 | 2022-06-15 | Maavrx Ltd | Expression vector |
| JP2024546964A (ja) | 2021-12-17 | 2024-12-26 | インペリアル カレッジ イノベイションズ リミテッド | Ｒｎａ構築物 |
| CN114317610B (zh) * | 2022-01-27 | 2024-07-02 | 上海本导基因技术有限公司 | 一种适用于帕金森疾病基因治疗的慢病毒载体 |
| WO2023202637A1 (en) | 2022-04-19 | 2023-10-26 | Shanghai Vitalgen Biopharma Co., Ltd. | Recombinant aav vectors for treating neurodegenerative disorders |
| CN117106825B (zh) * | 2023-08-28 | 2024-11-01 | 康霖生物科技（杭州）有限公司 | 用于治疗帕金森病的基因治疗载体及其用途 |
| CN118389675B (zh) * | 2024-05-27 | 2025-06-27 | 南方医科大学珠江医院 | 芳香族氨基酸脱羧酶作为标志物在肝性脑病的检测产品中的应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| DE4006630A1 (de) | 1990-03-03 | 1991-09-12 | Behringwerke Ag | Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung |
| US5512421A (en) | 1991-02-19 | 1996-04-30 | The Regents Of The University Of California | Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors |
| CA2111234C (en) | 1991-06-21 | 2002-11-26 | Manoj Chalam | Method for increasing rainout from autorefrigerated vaporous cloud containing hydrofluoric acid |
| US6001650A (en) | 1995-08-03 | 1999-12-14 | Avigen, Inc. | High-efficiency wild-type-free AAV helper functions |
| AU1073797A (en) * | 1995-11-14 | 1997-06-05 | Somatix Therapy Corporation | Joint expression of gtp cyclohydrolase and tyrosine hydroxylase |
| US5866552A (en) | 1996-09-06 | 1999-02-02 | The Trustees Of The University Of Pennsylvania | Method for expressing a gene in the absence of an immune response |
| WO1999061639A2 (en) | 1998-05-22 | 1999-12-02 | Oxford Biomedica (Uk) Limited | Retroviral delivery system |
| PL332875A1 (en) | 1996-10-17 | 1999-10-25 | Oxford Biomedica Ltd | Retroviral vectors |
| GB9622500D0 (en) * | 1996-10-29 | 1997-01-08 | Oxford Biomedica Ltd | Therapeutic gene |
| GB9720465D0 (en) | 1997-09-25 | 1997-11-26 | Oxford Biomedica Ltd | Dual-virus vectors |
| GB9803351D0 (en) | 1998-02-17 | 1998-04-15 | Oxford Biomedica Ltd | Anti-viral vectors |
| GB9904905D0 (en) | 1999-03-03 | 1999-04-28 | Oxford Biomedica Ltd | Cells |
| MXPA02000483A (es) | 1999-07-13 | 2002-07-02 | Pellicer Carlos F | Panel para la construccion e instalacion para su fabricacion. |
| GB0009760D0 (en) | 2000-04-19 | 2000-06-07 | Oxford Biomedica Ltd | Method |
| GB0024550D0 (https=) * | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| EP1504108B1 (en) | 2002-02-01 | 2013-04-17 | Oxford Biomedica (UK) Limited | Lentiviral vector |
| SE0302509D0 (sv) | 2003-09-19 | 2003-09-19 | Amersham Biosciences Ab | Matrix for separation of polyethers and method of separation |
| US7943374B2 (en) | 2005-08-21 | 2011-05-17 | Markus Hildinger | Super-size adeno-associated viral vector harboring a recombinant genome larger than 5.7 kb |
| GB0526211D0 (en) | 2005-12-22 | 2006-02-01 | Oxford Biomedica Ltd | Viral vectors |
| GB0526210D0 (en) | 2005-12-22 | 2006-02-01 | Oxford Biomedica Ltd | Vectors |
| US20090214478A1 (en) | 2008-02-21 | 2009-08-27 | Alberto Auricchio | Method of treating ocular diseases by gene therapy |
| PL2307551T3 (pl) | 2008-06-18 | 2017-07-31 | Oxford Biomedica (Uk) Limited | Oczyszczanie wektorów retrowirusowych |
| JP5559185B2 (ja) * | 2008-11-11 | 2014-07-23 | オックスフォード バイオメディカ（ユーケー）リミテッド | 方法 |
| CN102946907A (zh) * | 2010-05-28 | 2013-02-27 | 牛津生物医学（英国）有限公司 | 慢病毒载体向脑的递送 |
-
2011
- 2011-10-28 GB GBGB1118636.8A patent/GB201118636D0/en not_active Ceased
-
2012
- 2012-10-26 DK DK12778779.4T patent/DK2771471T3/en active
- 2012-10-26 CA CA2849241A patent/CA2849241C/en active Active
- 2012-10-26 DK DK17161437.3T patent/DK3219801T3/da active
- 2012-10-26 AU AU2012328166A patent/AU2012328166B2/en active Active
- 2012-10-26 CA CA3052407A patent/CA3052407C/en active Active
- 2012-10-26 ES ES12778779.4T patent/ES2628419T3/es active Active
- 2012-10-26 PL PL12778779T patent/PL2771471T3/pl unknown
- 2012-10-26 PL PL17161437T patent/PL3219801T3/pl unknown
- 2012-10-26 ES ES17161437T patent/ES2857003T3/es active Active
- 2012-10-26 WO PCT/GB2012/052668 patent/WO2013061076A1/en not_active Ceased
- 2012-10-26 CN CN201710722658.7A patent/CN107523581B/zh active Active
- 2012-10-26 EP EP12778779.4A patent/EP2771471B1/en active Active
- 2012-10-26 CN CN201280064927.0A patent/CN104011213B/zh active Active
- 2012-10-26 JP JP2014537726A patent/JP6296987B2/ja active Active
- 2012-10-26 EP EP17161437.3A patent/EP3219801B1/en active Active
-
2019
- 2019-06-26 US US16/454,024 patent/US11279954B2/en active Active
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