|
US5958930A
(en)
|
1991-04-08 |
1999-09-28 |
Duquesne University Of The Holy Ghost |
Pyrrolo pyrimidine and furo pyrimidine derivatives
|
|
AU3176297A
(en)
|
1996-06-25 |
1998-01-14 |
Novartis Ag |
Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
|
|
US20080248046A1
(en)
|
1997-03-17 |
2008-10-09 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5
|
|
AR035885A1
(es)
*
|
2001-05-14 |
2004-07-21 |
Novartis Ag |
Derivados de 4-amino-5-fenil-7-ciclobutilpirrolo (2,3-d)pirimidina, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos derivados para la preparacion de una composicion farmaceutica
|
|
ES2309206T3
(es)
|
2001-10-02 |
2008-12-16 |
Smithkline Beecham Corporation |
Compuestos quimicos.
|
|
DE10239042A1
(de)
|
2002-08-21 |
2004-03-04 |
Schering Ag |
Makrozyclische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
|
|
ES2304252T3
(es)
|
2003-05-28 |
2008-10-01 |
Universita Degli Studi Di Siena |
Derivados sustituidos en posicion 4 de pirazolo(3,4-d)pirimidina y utilizaciones de los mismos.
|
|
US7504396B2
(en)
|
2003-06-24 |
2009-03-17 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
GB0320728D0
(en)
|
2003-09-04 |
2003-10-08 |
Kilminster Shaun |
Test
|
|
KR20060070572A
(ko)
|
2003-09-18 |
2006-06-23 |
콘포마 세러퓨틱스 코포레이션 |
Hsp90-저해제로서의 신규 헤테로시클릭 화합물
|
|
ATE481134T1
(de)
|
2004-01-21 |
2010-10-15 |
Univ Emory |
Zusammensetzungen und verwendung von tyrosinkinase-hemmern zur behandlung von pathogenen infektionen
|
|
JP2007520559A
(ja)
*
|
2004-02-03 |
2007-07-26 |
アボット・ラボラトリーズ |
治療薬としてのアミノベンゾオキサゾール類
|
|
EP1713806B1
(en)
*
|
2004-02-14 |
2013-05-08 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
WO2005095382A1
(ja)
|
2004-03-30 |
2005-10-13 |
Kyowa Hakko Kogyo Co., Ltd. |
抗腫瘍剤
|
|
WO2005099688A2
(en)
*
|
2004-04-07 |
2005-10-27 |
Takeda Pharmaceutical Company Limited |
Cyclic compounds
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
RU2405778C2
(ru)
|
2004-09-30 |
2010-12-10 |
Тиботек Фармасьютикалз Лтд. |
5-гетероциклилпиримидины, ингибирующие вич
|
|
US7906528B2
(en)
*
|
2004-10-05 |
2011-03-15 |
Novartis International Pharmaceutical Ltd. |
Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds
|
|
EP1710246A1
(en)
|
2005-04-08 |
2006-10-11 |
Schering Aktiengesellschaft |
Sulfoximine-pyrimidine Macrocycles and the salts thereof, a process for making them, and their pharmaceutical use against cancer
|
|
US20070105874A1
(en)
*
|
2005-09-23 |
2007-05-10 |
Conforma Therapeutics Corporation |
Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors
|
|
US7547782B2
(en)
|
2005-09-30 |
2009-06-16 |
Bristol-Myers Squibb Company |
Met kinase inhibitors
|
|
TWI333953B
(en)
|
2005-10-06 |
2010-12-01 |
Schering Corp |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
EA017812B1
(ru)
|
2005-12-08 |
2013-03-29 |
Медарекс, Инк. |
Выделенное моноклональное антитело или его антигенсвязывающий участок, которые связываются с протеинтирозинкиназой 7 ( ptk7) человека, и их применение
|
|
JP2009520028A
(ja)
*
|
2005-12-19 |
2009-05-21 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
Igfr抑制剤および抗癌剤の併用
|
|
EP1803723A1
(de)
|
2006-01-03 |
2007-07-04 |
Bayer Schering Pharma Aktiengesellschaft |
(2,4,9-triaza-1(2,4)-pyrimidina-3(1,3)-benzenacyclononaphan-3^4-yl)-sulfoximid derivate als selektive inhibitoren der aurora kinase zur behandlung von krebs
|
|
WO2007113254A1
(en)
|
2006-03-30 |
2007-10-11 |
Tibotec Pharmaceuticals Ltd. |
Hiv inhibiting 5-amido substituted pyrimidines
|
|
CA2651072A1
(en)
|
2006-05-01 |
2007-11-08 |
Pfizer Products Inc. |
Substituted 2-amino-fused heterocyclic compounds
|
|
GB0610242D0
(en)
|
2006-05-23 |
2006-07-05 |
Novartis Ag |
Organic compounds
|
|
TWI398252B
(zh)
|
2006-05-26 |
2013-06-11 |
諾華公司 |
吡咯并嘧啶化合物及其用途
|
|
WO2009032703A1
(en)
|
2007-08-28 |
2009-03-12 |
Irm Llc |
2- (het) arylamino-6-aminopyridine derivatives and fused forms thereof as anaplastic lymphoma kinase inhibitors
|
|
AU2008309517B2
(en)
|
2007-10-12 |
2013-03-14 |
Astrazeneca Ab |
Inhibitors of protein kinases
|
|
EP2217716A4
(en)
|
2007-11-09 |
2011-02-09 |
Salk Inst For Biological Studi |
USE OF TAM RECEPTOR INHIBITORS AS ANTIMICROBIAL AGENTS
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
US8399206B2
(en)
|
2008-07-10 |
2013-03-19 |
Nodality, Inc. |
Methods for diagnosis, prognosis and methods of treatment
|
|
US20120230991A1
(en)
|
2008-07-29 |
2012-09-13 |
Douglas Kim Graham |
Methods and compounds for enhancing anti-cancer therapy
|
|
US8569466B2
(en)
|
2008-09-10 |
2013-10-29 |
Nnochiri Ekwuribe |
Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers
|
|
TW201016676A
(en)
|
2008-10-03 |
2010-05-01 |
Astrazeneca Ab |
Heterocyclic derivatives and methods of use thereof
|
|
GB0819105D0
(en)
|
2008-10-17 |
2008-11-26 |
Chroma Therapeutics Ltd |
Pyrrolo-pyrimidine compounds
|
|
US8513242B2
(en)
|
2008-12-12 |
2013-08-20 |
Cystic Fibrosis Foundation Therapeutics, Inc. |
Pyrimidine compounds and methods of making and using same
|
|
US8765727B2
(en)
|
2009-01-23 |
2014-07-01 |
Incyte Corporation |
Macrocyclic compounds and their use as kinase inhibitors
|
|
TW201102391A
(en)
*
|
2009-03-31 |
2011-01-16 |
Biogen Idec Inc |
Certain substituted pyrimidines, pharmaceutical compositions thereof, and methods for their use
|
|
UA107791C2
(en)
|
2009-05-05 |
2015-02-25 |
Dow Agrosciences Llc |
Pesticidal compositions
|
|
AR076550A1
(es)
|
2009-05-06 |
2011-06-22 |
Portola Pharm Inc |
Inhibidores de la janus tirosina kinasa (jak)
|
|
ES2666152T3
(es)
|
2009-08-13 |
2018-05-03 |
The Johns Hopkins University |
Métodos de modulación de la función inmunitaria con anticuerpos anti-B7-H7CR
|
|
WO2011029915A1
(en)
*
|
2009-09-10 |
2011-03-17 |
Novartis Ag |
Ether derivatives of bicyclic heteroaryls
|
|
WO2011065800A2
(ko)
|
2009-11-30 |
2011-06-03 |
주식회사 오스코텍 |
피리미딘 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물
|
|
EP2536410B1
(en)
|
2010-02-18 |
2015-09-23 |
Merck Sharp & Dohme Corp. |
Substituted pyrimidine derivatives and their use in treating viral infections
|
|
GB201004311D0
(en)
|
2010-03-15 |
2010-04-28 |
Proximagen Ltd |
New enzyme inhibitor compounds
|
|
US9133123B2
(en)
|
2010-04-23 |
2015-09-15 |
Cytokinetics, Inc. |
Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
|
|
WO2011146313A1
(en)
*
|
2010-05-19 |
2011-11-24 |
The University Of North Carolina At Chapel Hill |
Pyrazolopyrimidine compounds for the treatment of cancer
|
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
|
JP2014005206A
(ja)
|
2010-10-22 |
2014-01-16 |
Astellas Pharma Inc |
アリールアミノヘテロ環カルボキサミド化合物
|
|
CN103221048A
(zh)
|
2010-11-18 |
2013-07-24 |
卡斯纳莱拉创新药物私人有限公司 |
取代的4-(硒吩-2(或3)-基氨基)嘧啶化合物及其使用方法
|
|
US8362023B2
(en)
|
2011-01-19 |
2013-01-29 |
Hoffmann-La Roche Inc. |
Pyrazolo pyrimidines
|
|
US9376438B2
(en)
|
2011-05-17 |
2016-06-28 |
Principia Biopharma, Inc. |
Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
|
|
KR20140075693A
(ko)
|
2011-08-29 |
2014-06-19 |
인피니티 파마슈티칼스, 인코포레이티드 |
헤테로사이클릭 화합물 및 그의 용도
|
|
KR20140059246A
(ko)
|
2011-09-22 |
2014-05-15 |
화이자 인코포레이티드 |
피롤로피리미딘 및 퓨린 유도체
|
|
BR112014007788A2
(pt)
|
2011-10-03 |
2017-04-18 |
Univ North Carolina Chapel Hill |
compostos de pirrolopirimidina para tratamento do câncer
|
|
EP2817328A1
(en)
|
2012-02-21 |
2014-12-31 |
Institut National de la Santé et de la Recherche Médicale |
Tam receptors as virus entry cofactors
|
|
AU2013250726B2
(en)
|
2012-04-20 |
2017-01-05 |
Advinus Therapeutics Limited |
Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof
|
|
CN104302627A
(zh)
|
2012-05-22 |
2015-01-21 |
北卡罗来纳大学教堂山分校 |
用于治疗癌症的嘧啶化合物
|
|
WO2014062774A1
(en)
|
2012-10-17 |
2014-04-24 |
The University Of North Carolina At Chapel Hill |
Pyrazolopyrimidine compounds for the treatment of cancer
|
|
US9771330B2
(en)
|
2012-11-27 |
2017-09-26 |
The University Of North Carolina At Chapel Hill |
Pyrimidine compounds for the treatment of cancer
|
|
WO2015153978A1
(en)
|
2014-04-04 |
2015-10-08 |
The University Of North Carolina At Chapel Hill |
Methods for the treatment of tumors
|
|
US20150291606A1
(en)
|
2014-04-11 |
2015-10-15 |
The University Of North Carolina At Chapel Hill |
Mertk-specific pyrrolopyrimidine compounds
|