JP2014526342A5 - - Google Patents
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- Publication number
- JP2014526342A5 JP2014526342A5 JP2014530798A JP2014530798A JP2014526342A5 JP 2014526342 A5 JP2014526342 A5 JP 2014526342A5 JP 2014530798 A JP2014530798 A JP 2014530798A JP 2014530798 A JP2014530798 A JP 2014530798A JP 2014526342 A5 JP2014526342 A5 JP 2014526342A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- hyaluronic acid
- additive
- vitamin
- acid component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 46
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 22
- 229920002674 hyaluronan Polymers 0.000 claims 22
- 229960003160 hyaluronic acid Drugs 0.000 claims 22
- 239000000654 additive Substances 0.000 claims 14
- 230000000996 additive effect Effects 0.000 claims 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 6
- 150000003700 vitamin C derivatives Chemical class 0.000 claims 6
- 239000000945 filler Substances 0.000 claims 4
- SHKUUQIDMUMQQK-UHFFFAOYSA-N 2-[4-(oxiran-2-ylmethoxy)butoxymethyl]oxirane Chemical group C1OC1COCCCCOCC1CO1 SHKUUQIDMUMQQK-UHFFFAOYSA-N 0.000 claims 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 3
- MLSJBGYKDYSOAE-DCWMUDTNSA-N L-Ascorbic acid-2-glucoside Chemical group OC[C@H](O)[C@H]1OC(=O)C(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1O MLSJBGYKDYSOAE-DCWMUDTNSA-N 0.000 claims 3
- 229930003268 Vitamin C Natural products 0.000 claims 3
- 238000004132 cross linking Methods 0.000 claims 3
- 239000011718 vitamin C Substances 0.000 claims 3
- 235000019154 vitamin C Nutrition 0.000 claims 3
- 239000003431 cross linking reagent Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- 230000003444 anaesthetic effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000007972 injectable composition Substances 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161534780P | 2011-09-14 | 2011-09-14 | |
| US61/534,780 | 2011-09-14 | ||
| USPCT/US2012/052125 | 2012-08-23 | ||
| PCT/US2012/052125 WO2013028904A2 (en) | 2011-08-25 | 2012-08-23 | Dermal filler compositions including antioxidants |
| PCT/US2012/055211 WO2013040242A2 (en) | 2011-09-14 | 2012-09-13 | Dermal filler compositions for fine line treatment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075224A Division JP2017140433A (ja) | 2011-09-14 | 2017-04-05 | 酸化防止剤を含む皮膚充填剤組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014526342A JP2014526342A (ja) | 2014-10-06 |
| JP2014526342A5 true JP2014526342A5 (https=) | 2015-11-05 |
| JP6125509B2 JP6125509B2 (ja) | 2017-05-10 |
Family
ID=47883970
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014530798A Expired - Fee Related JP6125509B2 (ja) | 2011-09-14 | 2012-09-13 | 酸化防止剤を含む皮膚充填剤組成物 |
| JP2017075224A Withdrawn JP2017140433A (ja) | 2011-09-14 | 2017-04-05 | 酸化防止剤を含む皮膚充填剤組成物 |
| JP2018219395A Withdrawn JP2019058692A (ja) | 2011-09-14 | 2018-11-22 | 酸化防止剤を含む皮膚充填剤組成物 |
| JP2021048584A Pending JP2021100603A (ja) | 2011-09-14 | 2021-03-23 | 酸化防止剤を含む皮膚充填剤組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075224A Withdrawn JP2017140433A (ja) | 2011-09-14 | 2017-04-05 | 酸化防止剤を含む皮膚充填剤組成物 |
| JP2018219395A Withdrawn JP2019058692A (ja) | 2011-09-14 | 2018-11-22 | 酸化防止剤を含む皮膚充填剤組成物 |
| JP2021048584A Pending JP2021100603A (ja) | 2011-09-14 | 2021-03-23 | 酸化防止剤を含む皮膚充填剤組成物 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP2755630A2 (https=) |
| JP (4) | JP6125509B2 (https=) |
| KR (4) | KR20220013588A (https=) |
| CN (2) | CN108379112A (https=) |
| AU (1) | AU2012308503B2 (https=) |
| CA (1) | CA2848833C (https=) |
| HK (1) | HK1198124A1 (https=) |
| RU (1) | RU2626513C2 (https=) |
| WO (1) | WO2013040242A2 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| EP2484387A1 (en) | 2011-02-03 | 2012-08-08 | Q-Med AB | Hyaluronic acid composition |
| US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
| US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| KR102238406B1 (ko) | 2011-06-03 | 2021-04-08 | 알러간 인더스트리 에스에이에스 | 항산화제를 포함하는 피부 충전제 조성물 |
| CN108379112A (zh) * | 2011-09-14 | 2018-08-10 | 阿勒根公司 | 用于细纹治疗的真皮填充剂组合物 |
| KR20210071106A (ko) * | 2011-12-08 | 2021-06-15 | 알러간 인더스트리 에스에이에스 | 진피 필러 조성물 |
| US20140315828A1 (en) * | 2013-04-22 | 2014-10-23 | Allergan, Inc. | Cross-linked silk-hyaluronic acid compositions |
| WO2014172784A1 (en) * | 2013-04-25 | 2014-10-30 | Aluron Biopharma Inc. | Crosslinked hyaluronic acid compositions |
| WO2016128783A1 (en) * | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
| HUE047971T2 (hu) | 2015-02-13 | 2020-05-28 | Allergan Ind Sas | Az arcelemek - például az áll - formázására, megnagyobbítására vagy korrekciójára szolgáló implantátumok |
| US10988600B2 (en) * | 2016-06-23 | 2021-04-27 | Galderma Holding SA | Cyclodextrin-grafted cross-linked hyaluronic acid complexed with active drug substances and uses thereof |
| EP3503841A4 (en) | 2016-08-24 | 2020-04-22 | Allergan, Inc. | CO-CROSSLINKED HYALURONIC ACID-FIBROIN HYDROGELS FOR IMPROVING THE SUSTAINABILITY OF TISSUE GRAFTS AND FOR INCREASING SOFT TISSUES |
| EP4670750A3 (en) * | 2017-06-12 | 2026-03-04 | Advanced Aesthetic Technologies, Inc. | Dermal filler |
| US20230190997A1 (en) | 2017-06-26 | 2023-06-22 | Evolved By Nature, Inc. | Silk-hyaluronic acid based tissue filers and methods of using the same |
| AU2018290810C1 (en) * | 2017-06-26 | 2024-09-12 | Evolved By Nature, Inc. | Silk-hyaluronic acid based tissue fillers and methods of using the same |
| CA3069968A1 (en) * | 2017-07-19 | 2019-01-24 | Dentsply Sirona Inc. | Water-soluble hydrogel-based dental composition and methods of making and using same |
| CN111918640A (zh) * | 2017-12-29 | 2020-11-10 | 马特克斯拉比有限公司 | 具有透明质酸基的填充物的制备方法 |
| KR101967153B1 (ko) | 2018-04-04 | 2019-04-09 | 윤성준 | 주름과 피부 결손 및 위축성 흉터 개선을 위한 필러 배합 조성물 |
| WO2019238954A1 (en) * | 2018-06-15 | 2019-12-19 | Croma-Pharma Gmbh | Hydrogel composition comprising a crosslinked polymer |
| EP3804769B1 (en) | 2018-07-06 | 2025-05-21 | Lg Chem, Ltd. | Hyaluronic acid filler having high viscoelasticity and high cohesiveness |
| AU2019405953B2 (en) | 2018-12-19 | 2025-09-18 | Evolved By Nature, Inc. | Silk-hyaluronic acid tissue fillers and methods of making and using the same |
| IT201900006929A1 (it) * | 2019-05-16 | 2020-11-16 | Giuliani Spa | Kit per il trattamento estetico della pelle |
| CN110467689A (zh) * | 2019-09-09 | 2019-11-19 | 山东众山生物科技有限公司 | 一种透明质酸衍生物及其制备方法 |
| CN110907370A (zh) * | 2019-12-04 | 2020-03-24 | 桂林理工大学 | 一种普适性的超灵敏化学与生物比色传感方法 |
| US20230040919A1 (en) * | 2019-12-26 | 2023-02-09 | Allergan, Inc. | Crosslinked ha-collagen hydrogels as dermal fillers |
| CN111249172A (zh) * | 2020-01-15 | 2020-06-09 | 陈勇 | 一种美容注射凝胶及其制备方法 |
| AR128245A1 (es) | 2022-01-11 | 2024-04-10 | Gpq S R L | Nuevos derivados de ácido hialurónico como rellenos innovadores |
| WO2024055132A1 (es) * | 2022-09-12 | 2024-03-21 | Universidad De Talca | Método para la síntesis de un copolímero ramificado de ácido hialurónico y ácido poli(láctico-co-glicólico) |
| KR102782287B1 (ko) | 2022-12-19 | 2025-03-18 | 주식회사 코루파마 | 히알루론산과 아가 또는 아가로오스 복합화 하이드로겔 제조방법, 이로부터 제조된 히알루론산과 아가 또는 아가로오스를 포함하는 하이드로겔 및 이를 포함하는 필러 조성물 |
| EP4450062A1 (en) * | 2023-04-20 | 2024-10-23 | Abiogen Pharma S.p.A. | Composition for the treatment of osteoarthrosis |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174999B1 (en) * | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
| KR100721752B1 (ko) * | 2000-01-24 | 2007-05-25 | 쿠라레 메디카루 가부시키가이샤 | 수팽윤성 고분자 겔 및 그 제조법 |
| IT1317091B1 (it) * | 2000-02-08 | 2003-05-26 | S F I R Societa Fondaria Ind R | Gel di acido ialuronico cross-linked con l-amminoacidi ol-amminoesteri bifunzionali. |
| FR2811996B1 (fr) | 2000-07-19 | 2003-08-08 | Corneal Ind | Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations |
| WO2004067575A1 (en) * | 2003-01-31 | 2004-08-12 | Biosphere S.P.A. | Water soluble and biocompatible gels of hyaluronic acid cross-linked with bi-functional l-aminoacids or l-aminoesters |
| AU2003206922A1 (en) | 2003-02-19 | 2004-09-09 | Aventis Pharmaceuticals Holdings Inc. | Composition and method for intradermal soft tissue augmentation |
| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| US8124120B2 (en) * | 2003-12-22 | 2012-02-28 | Anika Therapeutics, Inc. | Crosslinked hyaluronic acid compositions for tissue augmentation |
| CA2550718C (en) * | 2003-12-30 | 2013-11-05 | Genzyme Corporation | Cohesive gels from cross-linked hyaluronan and/or hylan, their preparation and use |
| FR2865737B1 (fr) * | 2004-02-03 | 2006-03-31 | Anteis Sa | Gel reticule biocompatible |
| EP1750769B1 (en) * | 2004-05-20 | 2013-01-23 | Mentor Worldwide LLC | Methods for making injectable polymer hydrogels |
| FR2873379B1 (fr) * | 2004-07-23 | 2008-05-16 | Jerome Asius | Procede de preparation d'acide hyaluronique reticule, acide hyaluronique reticule susceptible d'etre obtenu par ledit procede, implant contenant ledit acide hyaluronique reticule, et son utilisation |
| FR2878444B1 (fr) | 2004-11-30 | 2008-04-25 | Corneal Ind Soc Par Actions Si | Solutions viscoelastiques renfermant du hyaluronate de sodiu et de l'hydroxypropylmethylcellulose, preparation et utilisations |
| KR20080067619A (ko) * | 2005-09-15 | 2008-07-21 | 유니버시티 오브 유타 리써치 파운데이션 | 고분자 조성물 및 이의 제조방법, 및 이의 용도 |
| US20100273734A1 (en) * | 2006-02-28 | 2010-10-28 | Novozymes Biopolymer A/S | Derivatives of Hyaluronic Acids |
| CN1837265A (zh) * | 2006-04-25 | 2006-09-27 | 江南大学 | 一种透明质酸－羧甲基纤维素复合改性的方法 |
| CN100417666C (zh) * | 2006-09-07 | 2008-09-10 | 重庆大学 | 赖氨酸-壳聚糖树脂及其制备方法 |
| FR2908415B1 (fr) * | 2006-11-10 | 2009-01-23 | Abr Dev Sarl | Acide hyaluronique reticule et son procede de preparation |
| FR2909560B1 (fr) * | 2006-12-06 | 2012-12-28 | Fabre Pierre Dermo Cosmetique | Gel d'acide hyaluronique pour injection intradermique |
| FR2918377B1 (fr) * | 2007-07-05 | 2010-10-08 | Estelle Piron | Gel co-reticule de polysaccharides |
| US8394782B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
| JP2011507841A (ja) * | 2007-12-21 | 2011-03-10 | エンセコール アーベー | 活性物質を含む架橋したヒドロゲル |
| KR20090110090A (ko) * | 2008-04-17 | 2009-10-21 | 엘지전자 주식회사 | 초음파를 이용한 인듐 셀레나이드 나노화합물의 제조방법및 이를 포함하는 화합물 반도체 태양전지 |
| US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
| CN101961344A (zh) * | 2009-07-23 | 2011-02-02 | 山东省生物药物研究院 | 药物组合物及其应用 |
| IT1395392B1 (it) * | 2009-08-27 | 2012-09-14 | Fidia Farmaceutici | Geli viscoelastici come nuovi filler |
| EP2504025A4 (en) * | 2009-11-23 | 2013-05-01 | Stephen F Olmstead | COMPOSITIONS AND METHODS USING SERRATIA PEPTIDASE FOR INHIBITING AND TREATING BIOFILMS ASSOCIATED WITH PARTICULAR SUFFERING |
| US20110171286A1 (en) | 2010-01-13 | 2011-07-14 | Allergan, Inc. | Hyaluronic acid compositions for dermatological use |
| US20110171311A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| US20110172180A1 (en) * | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| KR102238406B1 (ko) * | 2011-06-03 | 2021-04-08 | 알러간 인더스트리 에스에이에스 | 항산화제를 포함하는 피부 충전제 조성물 |
| CN108379112A (zh) * | 2011-09-14 | 2018-08-10 | 阿勒根公司 | 用于细纹治疗的真皮填充剂组合物 |
-
2012
- 2012-09-13 CN CN201810249654.6A patent/CN108379112A/zh active Pending
- 2012-09-13 EP EP12769798.5A patent/EP2755630A2/en not_active Withdrawn
- 2012-09-13 CA CA2848833A patent/CA2848833C/en active Active
- 2012-09-13 WO PCT/US2012/055211 patent/WO2013040242A2/en not_active Ceased
- 2012-09-13 CN CN201280055657.7A patent/CN104105474B/zh not_active Expired - Fee Related
- 2012-09-13 KR KR1020227001920A patent/KR20220013588A/ko not_active Withdrawn
- 2012-09-13 HK HK14111615.6A patent/HK1198124A1/xx unknown
- 2012-09-13 KR KR1020207027527A patent/KR20200116168A/ko not_active Ceased
- 2012-09-13 RU RU2014113663A patent/RU2626513C2/ru active
- 2012-09-13 KR KR1020217032224A patent/KR20210125119A/ko not_active Abandoned
- 2012-09-13 JP JP2014530798A patent/JP6125509B2/ja not_active Expired - Fee Related
- 2012-09-13 AU AU2012308503A patent/AU2012308503B2/en not_active Ceased
- 2012-09-13 KR KR1020147009782A patent/KR102161861B1/ko not_active Expired - Fee Related
-
2017
- 2017-04-05 JP JP2017075224A patent/JP2017140433A/ja not_active Withdrawn
-
2018
- 2018-11-22 JP JP2018219395A patent/JP2019058692A/ja not_active Withdrawn
-
2021
- 2021-03-23 JP JP2021048584A patent/JP2021100603A/ja active Pending
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