JP2014525429A - Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ抗原のアジュバント添加処方物 - Google Patents

Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ抗原のアジュバント添加処方物 Download PDF

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Publication number
JP2014525429A
JP2014525429A JP2014527686A JP2014527686A JP2014525429A JP 2014525429 A JP2014525429 A JP 2014525429A JP 2014527686 A JP2014527686 A JP 2014527686A JP 2014527686 A JP2014527686 A JP 2014527686A JP 2014525429 A JP2014525429 A JP 2014525429A
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Japan
Prior art keywords
seq
antigen
tlr agonist
aureus
polypeptide
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JP2014527686A
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Japanese (ja)
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JP2014525429A5 (cg-RX-API-DMAC7.html
Inventor
ファビオ バグノーリ，
バーバラ バウドナー，
シモーネ ブファーリ，
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ノバルティス アーゲー
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Publication of JP2014525429A publication Critical patent/JP2014525429A/ja
Publication of JP2014525429A5 publication Critical patent/JP2014525429A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
JP2014527686A 2011-09-01 2012-08-31 Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ抗原のアジュバント添加処方物 Pending JP2014525429A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161530162P 2011-09-01 2011-09-01
US61/530,162 2011-09-01
US201261607999P 2012-03-07 2012-03-07
US61/607,999 2012-03-07
PCT/EP2012/067032 WO2013030378A1 (en) 2011-09-01 2012-08-31 Adjuvanted formulations of staphylococcus aureus antigens

Publications (2)

Publication Number Publication Date
JP2014525429A true JP2014525429A (ja) 2014-09-29
JP2014525429A5 JP2014525429A5 (cg-RX-API-DMAC7.html) 2015-10-01

Family

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Family Applications (1)

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JP2014527686A Pending JP2014525429A (ja) 2011-09-01 2012-08-31 Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ抗原のアジュバント添加処方物

Country Status (14)

Country Link
US (1) US20140363461A1 (cg-RX-API-DMAC7.html)
EP (1) EP2763695A1 (cg-RX-API-DMAC7.html)
JP (1) JP2014525429A (cg-RX-API-DMAC7.html)
KR (1) KR20140066212A (cg-RX-API-DMAC7.html)
CN (1) CN104093418A (cg-RX-API-DMAC7.html)
AU (1) AU2012300765A1 (cg-RX-API-DMAC7.html)
BR (1) BR112014004782A2 (cg-RX-API-DMAC7.html)
CA (1) CA2847204A1 (cg-RX-API-DMAC7.html)
IL (1) IL231104A0 (cg-RX-API-DMAC7.html)
IN (1) IN2014CN02152A (cg-RX-API-DMAC7.html)
MX (1) MX2014002363A (cg-RX-API-DMAC7.html)
RU (1) RU2014112343A (cg-RX-API-DMAC7.html)
SG (1) SG11201400210RA (cg-RX-API-DMAC7.html)
WO (1) WO2013030378A1 (cg-RX-API-DMAC7.html)

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WO2014033193A1 (en) * 2012-08-31 2014-03-06 Novartis Ag Stabilised proteins for immunising against staphylococcus aureus
BE1022359B1 (fr) * 2014-03-17 2016-03-25 Glaxosmithkline Biologicals Sa Immunisation contre des infections staphylococciques des os et des articulations
JP6894237B2 (ja) * 2014-03-26 2021-06-30 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 変異体ブドウ球菌抗原
BE1022875B1 (fr) * 2014-03-26 2016-09-30 Glaxosmithkline Biologicals S.A. Compositions pour une immunisation contre staphylococcus aureus
CN105646681B (zh) * 2016-01-21 2021-07-16 浙江海隆生物科技有限公司 一种奶牛金黄色葡萄球菌α-溶血素亚单位疫苗的制备方法及应用
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WO2010119343A2 (en) * 2009-04-14 2010-10-21 Novartis Ag Compositions for immunising against staphylococcus aureus
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Also Published As

Publication number Publication date
AU2012300765A1 (en) 2014-03-13
BR112014004782A2 (pt) 2017-03-21
MX2014002363A (es) 2014-04-14
SG11201400210RA (en) 2014-03-28
IN2014CN02152A (cg-RX-API-DMAC7.html) 2015-09-04
IL231104A0 (en) 2014-04-30
US20140363461A1 (en) 2014-12-11
CA2847204A1 (en) 2013-03-07
WO2013030378A1 (en) 2013-03-07
RU2014112343A (ru) 2015-10-10
EP2763695A1 (en) 2014-08-13
KR20140066212A (ko) 2014-05-30
CN104093418A (zh) 2014-10-08

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