JP2014520852A5 - - Google Patents
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- Publication number
- JP2014520852A5 JP2014520852A5 JP2014520273A JP2014520273A JP2014520852A5 JP 2014520852 A5 JP2014520852 A5 JP 2014520852A5 JP 2014520273 A JP2014520273 A JP 2014520273A JP 2014520273 A JP2014520273 A JP 2014520273A JP 2014520852 A5 JP2014520852 A5 JP 2014520852A5
- Authority
- JP
- Japan
- Prior art keywords
- buffer composition
- norovirus
- genogroup
- buffer
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000203 mixture Substances 0.000 claims 24
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 9
- 241001263478 Norovirus Species 0.000 claims 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 8
- 235000002639 sodium chloride Nutrition 0.000 claims 7
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-Histidine Natural products OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 4
- 229960002885 histidine Drugs 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229940035032 monophosphoryl lipid a Drugs 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 229940037003 alum Drugs 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 108090000565 Capsid Proteins Proteins 0.000 claims 1
- 102100023321 Ceruloplasmin Human genes 0.000 claims 1
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 claims 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims 1
- 235000011130 ammonium sulphate Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000001103 potassium chloride Substances 0.000 claims 1
- 235000011164 potassium chloride Nutrition 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 235000011083 sodium citrates Nutrition 0.000 claims 1
- 229910052938 sodium sulfate Inorganic materials 0.000 claims 1
- 235000011152 sodium sulphate Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161506447P | 2011-07-11 | 2011-07-11 | |
| US61/506,447 | 2011-07-11 | ||
| PCT/US2012/046222 WO2013009849A1 (en) | 2011-07-11 | 2012-07-11 | Parenteral norovirus vaccine formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091755A Division JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520852A JP2014520852A (ja) | 2014-08-25 |
| JP2014520852A5 true JP2014520852A5 (cg-RX-API-DMAC7.html) | 2015-09-03 |
| JP6208659B2 JP6208659B2 (ja) | 2017-10-04 |
Family
ID=47506489
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014520273A Active JP6208659B2 (ja) | 2011-07-11 | 2012-07-11 | 非経口ノロウイルスワクチン製剤 |
| JP2017091755A Active JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091755A Active JP6613259B2 (ja) | 2011-07-11 | 2017-05-02 | 非経口ノロウイルスワクチン製剤 |
Country Status (29)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2601970B1 (en) | 2006-09-29 | 2016-10-26 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| AU2008302276B2 (en) | 2006-09-29 | 2013-10-10 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| BR112014000656A2 (pt) | 2011-07-11 | 2017-02-14 | Takeda Vaccines Inc | formulações de vacina parenteral contra norovírus |
| EP3052631B1 (en) | 2013-10-03 | 2019-08-07 | Takeda Vaccines, Inc. | Methods of detection and removal of rhabdoviruses from cell lines |
| JP6556632B2 (ja) | 2013-12-16 | 2019-08-07 | 武田薬品工業株式会社 | マイクロニードル |
| CN107184970A (zh) * | 2017-02-16 | 2017-09-22 | 北京生物制品研究所有限责任公司 | 口服诺如病毒亚单位疫苗及lt作为该疫苗佐剂的用途 |
| GB201703644D0 (en) | 2017-03-07 | 2017-04-19 | Elopak As | Improvements in or relating to toller mounting arrangements |
| AU2018269319A1 (en) * | 2017-05-15 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| WO2019158653A1 (en) * | 2018-02-15 | 2019-08-22 | Icon Genetics Gmbh | Immunogenic composition and vaccine for generating an immune response to norovirus |
| US20210121511A1 (en) * | 2018-05-29 | 2021-04-29 | Unm Rainforest Innovations | Virus-like particle compositions and methods of using same |
| CN109265542B (zh) * | 2018-09-27 | 2021-06-15 | 国药中生生物技术研究院有限公司 | 特异性结合诺如病毒gii.4基因型vp1蛋白或vlp的抗体及其制备方法和应用 |
| AR117462A1 (es) * | 2018-12-20 | 2021-08-04 | Takeda Vaccines Inc | Vacuna contra norovirus, formulaciones y métodos |
| EP4087604A4 (en) * | 2020-01-08 | 2023-11-01 | Bharat Biotech International Limited | COMPOSITIONS OF VIRAL VACCINES AND THEIR PREPARATION METHODS |
| JPWO2022210742A1 (cg-RX-API-DMAC7.html) | 2021-03-29 | 2022-10-06 | ||
| EP4340874A1 (en) | 2021-05-21 | 2024-03-27 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| CN118252924A (zh) * | 2022-12-27 | 2024-06-28 | 远大赛威信生命科学(南京)有限公司 | 用于诱发哺乳动物针对诺如病毒的免疫反应的药物组合物及其制备方法和用途 |
| WO2025076792A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Product Co., Ltd. | Methods of preparing norovirus vaccine with low amounts of adjuvant |
| WO2025077799A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Method of preparing norovirus vaccine without adjuvant |
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2012
- 2012-07-11 BR BR112014000656A patent/BR112014000656A2/pt not_active Application Discontinuation
- 2012-07-11 EA EA202090699A patent/EA202090699A3/ru unknown
- 2012-07-11 MX MX2014000411A patent/MX356586B/es active IP Right Grant
- 2012-07-11 MX MX2018006816A patent/MX379496B/es unknown
- 2012-07-11 EP EP12811916.1A patent/EP2731621B1/en active Active
- 2012-07-11 EP EP17199372.8A patent/EP3299030B1/en active Active
- 2012-07-11 ES ES17199372T patent/ES2926487T3/es active Active
- 2012-07-11 CN CN201510262891.2A patent/CN105031637A/zh active Pending
- 2012-07-11 DK DK17199372.8T patent/DK3299030T3/da active
- 2012-07-11 CA CA2841356A patent/CA2841356C/en active Active
- 2012-07-11 AU AU2012282658A patent/AU2012282658B2/en active Active
- 2012-07-11 JP JP2014520273A patent/JP6208659B2/ja active Active
- 2012-07-11 PH PH1/2021/551773A patent/PH12021551773A1/en unknown
- 2012-07-11 EP EP22176978.9A patent/EP4112074A1/en active Pending
- 2012-07-11 PL PL12811916T patent/PL2731621T3/pl unknown
- 2012-07-11 SG SG10201605644WA patent/SG10201605644WA/en unknown
- 2012-07-11 GE GEAP201213384A patent/GEP201706668B/en unknown
- 2012-07-11 PH PH1/2014/500093A patent/PH12014500093A1/en unknown
- 2012-07-11 CR CR20190540A patent/CR20190540A/es unknown
- 2012-07-11 EA EA201792407A patent/EA035442B1/ru not_active IP Right Cessation
- 2012-07-11 WO PCT/US2012/046222 patent/WO2013009849A1/en not_active Ceased
- 2012-07-11 PE PE2014000054A patent/PE20140845A1/es active IP Right Grant
- 2012-07-11 CN CN201810373895.1A patent/CN108567975A/zh active Pending
- 2012-07-11 EA EA201490258A patent/EA029470B1/ru not_active IP Right Cessation
- 2012-07-11 HK HK14112697.5A patent/HK1199202A1/xx unknown
- 2012-07-11 CN CN201280043691.2A patent/CN103874507A/zh active Pending
- 2012-07-11 PL PL17199372.8T patent/PL3299030T3/pl unknown
- 2012-07-11 KR KR1020147003571A patent/KR102096937B1/ko active Active
- 2012-07-11 ES ES12811916.1T patent/ES2656527T3/es active Active
- 2012-07-11 MY MYPI2014000073A patent/MY170746A/en unknown
- 2012-11-07 UA UAA201401321A patent/UA117732C2/uk unknown
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2013
- 2013-03-15 US US13/840,403 patent/US9801934B2/en active Active
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2014
- 2014-01-07 TN TNP2014000008A patent/TN2014000008A1/en unknown
- 2014-01-07 IL IL230356A patent/IL230356B/en active IP Right Grant
- 2014-01-10 CL CL2014000082A patent/CL2014000082A1/es unknown
- 2014-01-10 DO DO2014000004A patent/DOP2014000004A/es unknown
- 2014-02-06 MA MA36741A patent/MA35414B1/fr unknown
- 2014-02-10 ZA ZA2014/01012A patent/ZA201401012B/en unknown
- 2014-02-11 CR CR20140069A patent/CR20140069A/es unknown
- 2014-02-11 EC ECSP14013201 patent/ECSP14013201A/es unknown
- 2014-12-18 HK HK16102061.2A patent/HK1215154A1/zh unknown
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2015
- 2015-02-09 ZA ZA2015/00915A patent/ZA201500915B/en unknown
- 2015-02-19 AU AU2015200836A patent/AU2015200836B2/en active Active
- 2015-07-10 US US14/796,614 patent/US9867876B2/en active Active
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2017
- 2017-05-02 JP JP2017091755A patent/JP6613259B2/ja active Active
- 2017-12-08 US US15/836,030 patent/US10675341B2/en active Active
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2018
- 2018-07-06 PH PH12018501515A patent/PH12018501515B1/en unknown
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2020
- 2020-06-05 US US16/894,291 patent/US11701420B2/en active Active
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2022
- 2022-02-04 DO DO2022000030A patent/DOP2022000030A/es unknown
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2023
- 2023-05-24 US US18/322,679 patent/US20230338503A1/en active Pending