JP2014517830A5 - - Google Patents
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- Publication number
- JP2014517830A5 JP2014517830A5 JP2014509383A JP2014509383A JP2014517830A5 JP 2014517830 A5 JP2014517830 A5 JP 2014517830A5 JP 2014509383 A JP2014509383 A JP 2014509383A JP 2014509383 A JP2014509383 A JP 2014509383A JP 2014517830 A5 JP2014517830 A5 JP 2014517830A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- composition
- living cells
- activated
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 80
- 238000000034 method Methods 0.000 claims 33
- 239000000872 buffer Substances 0.000 claims 27
- 230000000050 nutritive effect Effects 0.000 claims 27
- 239000000203 mixture Substances 0.000 claims 23
- 210000000447 Th1 cell Anatomy 0.000 claims 17
- 238000002360 preparation method Methods 0.000 claims 13
- 229960000074 biopharmaceutical Drugs 0.000 claims 7
- 238000009169 immunotherapy Methods 0.000 claims 7
- 108010029697 CD40 Ligand Proteins 0.000 claims 6
- 102100032937 CD40 ligand Human genes 0.000 claims 6
- 230000028327 secretion Effects 0.000 claims 5
- 102100037850 Interferon gamma Human genes 0.000 claims 4
- 108010074328 Interferon-gamma Proteins 0.000 claims 4
- 102000004127 Cytokines Human genes 0.000 claims 3
- 108090000695 Cytokines Proteins 0.000 claims 3
- 102000019034 Chemokines Human genes 0.000 claims 2
- 108010012236 Chemokines Proteins 0.000 claims 2
- 108010039471 Fas Ligand Protein Proteins 0.000 claims 2
- 102000001398 Granzyme Human genes 0.000 claims 2
- 108060005986 Granzyme Proteins 0.000 claims 2
- 102000004503 Perforin Human genes 0.000 claims 2
- 108010056995 Perforin Proteins 0.000 claims 2
- KHGNFPUMBJSZSM-UHFFFAOYSA-N Perforine Natural products COC1=C2CCC(O)C(CCC(C)(C)O)(OC)C2=NC2=C1C=CO2 KHGNFPUMBJSZSM-UHFFFAOYSA-N 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 102100031988 Tumor necrosis factor ligand superfamily member 6 Human genes 0.000 claims 2
- 239000007853 buffer solution Substances 0.000 claims 2
- 230000000139 costimulatory effect Effects 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 235000015097 nutrients Nutrition 0.000 claims 2
- 229930192851 perforin Natural products 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 230000032258 transport Effects 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161481991P | 2011-05-03 | 2011-05-03 | |
| US61/481,991 | 2011-05-03 | ||
| US201161528493P | 2011-08-29 | 2011-08-29 | |
| US61/528,493 | 2011-08-29 | ||
| US201161565225P | 2011-11-30 | 2011-11-30 | |
| US61/565,225 | 2011-11-30 | ||
| US201261582878P | 2012-01-04 | 2012-01-04 | |
| US61/582,878 | 2012-01-04 | ||
| PCT/US2012/036103 WO2012151266A1 (en) | 2011-05-03 | 2012-05-02 | Methods for handling biological drugs containing living cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014266252A Division JP6006288B2 (ja) | 2011-05-03 | 2014-12-26 | 柔軟性のある容器あるいは注射器 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517830A JP2014517830A (ja) | 2014-07-24 |
| JP2014517830A5 true JP2014517830A5 (enExample) | 2015-02-19 |
| JP5934783B2 JP5934783B2 (ja) | 2016-06-15 |
Family
ID=47108026
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014509383A Active JP5934783B2 (ja) | 2011-05-03 | 2012-05-02 | 生細胞を含む生物学的薬剤の取り扱い方法 |
| JP2014266252A Active JP6006288B2 (ja) | 2011-05-03 | 2014-12-26 | 柔軟性のある容器あるいは注射器 |
| JP2016174984A Active JP6359059B2 (ja) | 2011-05-03 | 2016-09-07 | 生細胞を含む生物学的薬剤の取り扱い方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014266252A Active JP6006288B2 (ja) | 2011-05-03 | 2014-12-26 | 柔軟性のある容器あるいは注射器 |
| JP2016174984A Active JP6359059B2 (ja) | 2011-05-03 | 2016-09-07 | 生細胞を含む生物学的薬剤の取り扱い方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10350242B2 (enExample) |
| EP (1) | EP2704741B1 (enExample) |
| JP (3) | JP5934783B2 (enExample) |
| KR (3) | KR102229108B1 (enExample) |
| CN (2) | CN108261423B (enExample) |
| AU (1) | AU2012250794B2 (enExample) |
| BR (1) | BR112013028257B1 (enExample) |
| CA (1) | CA2838041C (enExample) |
| DK (1) | DK2704741T3 (enExample) |
| ES (1) | ES2648136T3 (enExample) |
| HU (1) | HUE034995T2 (enExample) |
| IL (1) | IL229176B (enExample) |
| PH (1) | PH12013502253A1 (enExample) |
| PL (1) | PL2704741T3 (enExample) |
| PT (1) | PT2704741T (enExample) |
| SG (1) | SG194774A1 (enExample) |
| WO (1) | WO2012151266A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160095307A1 (en) | 2014-10-07 | 2016-04-07 | NuTech Medical, Inc. | Method and composition for hypothermic storage of placental tissue |
| WO2016075542A1 (en) * | 2014-11-11 | 2016-05-19 | Macrocure, Ltd. | Methods for extended storage of activated leukocyte compositions |
| JP6814593B2 (ja) * | 2016-10-14 | 2021-01-20 | 株式会社 バイオミメティクスシンパシーズ | 幹細胞及び投与システム |
| AU2019372673A1 (en) | 2018-11-01 | 2021-05-27 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Compositions and methods for T cell engineering |
| TW202100747A (zh) * | 2018-12-07 | 2021-01-01 | 中國大陸商亘喜生物科技（上海）有限公司 | 用於免疫治療之組合物及方法 |
| EP3968992A4 (en) * | 2019-05-15 | 2023-06-21 | Stemcyte, Inc. | PACKAGING AND SHIPPING HIGH CONCENTRATION CELLS |
| WO2022124307A1 (ja) | 2020-12-10 | 2022-06-16 | Ａｇｃ株式会社 | オキシアルキレン重合体、その製造方法、硬化性組成物、硬化物 |
| KR20230154796A (ko) | 2021-03-12 | 2023-11-09 | 에이지씨 가부시키가이샤 | 경화성 조성물 및 경화물 |
| EP4368671A4 (en) | 2021-07-07 | 2025-07-16 | Agc Inc | CURABLE COMPOSITION, CURED PRODUCT, ADHESIVE AND SEALANT |
| JPWO2023190640A1 (enExample) * | 2022-03-30 | 2023-10-05 | ||
| WO2023204067A1 (ja) | 2022-04-22 | 2023-10-26 | Ａｇｃ株式会社 | 硬化性組成物及びその硬化物 |
| JPWO2023204064A1 (enExample) | 2022-04-22 | 2023-10-26 | ||
| CN119072501A (zh) | 2022-04-27 | 2024-12-03 | Ａｇｃ株式会社 | 含反应性硅基团的有机聚合物的制造方法 |
| JPWO2023210582A1 (enExample) | 2022-04-27 | 2023-11-02 | ||
| JPWO2023233962A1 (enExample) | 2022-06-03 | 2023-12-07 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2439003A1 (fr) | 1978-10-20 | 1980-05-16 | Anvar | Nouvelles pieces d'osteosynthese, leur preparation et leur application |
| US5766920A (en) | 1982-08-11 | 1998-06-16 | Cellcor, Inc. | Ex vivo activation of immune cells |
| AU7873187A (en) | 1986-08-08 | 1988-02-24 | University Of Minnesota | Method of culturing leukocytes |
| ZA888978B (en) | 1987-12-04 | 1990-07-25 | Du Pont | Immobilized interleukin 2 and interleukin 2 containing a carboxylterminal extension |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US5126132A (en) | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| US5728388A (en) | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| US6204058B1 (en) | 1992-02-07 | 2001-03-20 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| WO1994012196A1 (en) | 1992-11-25 | 1994-06-09 | Tanox Biosystems, Inc. | Conjugates and constructs including anti-cd28 and anti-cd3 binding molecules |
| AU7478394A (en) | 1993-08-06 | 1995-02-28 | Cytel Corporation | Methods for (ex vivo) therapy using peptide-loaded antigen presenting cells for the activation of ctl |
| IL107483A0 (en) | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| ES2201177T3 (es) | 1995-03-08 | 2004-03-16 | The Scripps Research Institute | Sistema de presentacion de antigenos y activacion de celulas-t. |
| DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| CA2254975C (en) | 1996-05-23 | 2008-12-16 | The Scripps Research Institute | Mhc class ii antigen-presenting systems and methods for activating cd4+ t cells |
| KR20000049096A (ko) * | 1996-10-11 | 2000-07-25 | 린다 에스. 스티븐슨 | 혼합 림프구와 조합된 종양세포를 사용하는 암 면역요법 |
| CA2274004A1 (en) | 1996-12-03 | 1998-06-11 | Osteobiologics, Inc. | Biodegradable polymeric film |
| WO1998033891A1 (en) | 1997-01-31 | 1998-08-06 | Hemosol Inc. | Method for the production of selected lymphocytes |
| US7282198B2 (en) | 1997-03-19 | 2007-10-16 | The University Of Arkansas For Medical Sciences | Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme |
| DE69840171D1 (de) | 1997-05-30 | 2008-12-11 | Osteobiologics Inc | Faserverstärkte,poröse,biologisch abbaubare implantatvorrichtung |
| JP2001522806A (ja) | 1997-11-10 | 2001-11-20 | アーチ・デヴェロップメント・コーポレイション | エクス・ビボ活性化ｔ細胞を用いる腫瘍および腫瘍細胞の処理方法 |
| JP2001054563A (ja) | 1999-07-12 | 2001-02-27 | Isotis Bv | 縫合糸 |
| US7112576B1 (en) | 1999-12-10 | 2006-09-26 | Regents Of The University Of Minnesota | Compositions and methods for cryopreservation of peripheral blood lymphocytes |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| DK1257632T3 (da) | 2000-02-24 | 2008-01-28 | Xcyte Therapies Inc | Samtidig stimulering og opkoncentrering af celler |
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| AU2001292564A1 (en) | 2000-08-31 | 2002-03-13 | Emory University | A method of transplantation using chemotherapy-treated allogeneic cells that enhance immune responses without graft versus host disease |
| US6626950B2 (en) | 2001-06-28 | 2003-09-30 | Ethicon, Inc. | Composite scaffold with post anchor for the repair and regeneration of tissue |
| AU2002342299A1 (en) | 2001-10-31 | 2003-05-12 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of | Generation of use of tc1 and tc2 cells |
| US7105580B2 (en) | 2001-12-06 | 2006-09-12 | University Of Washington | Porous structures useful for growing living tissue, and methods of manufacture |
| US20030175272A1 (en) * | 2002-03-07 | 2003-09-18 | Medcell Biologics, Inc. | Re-activated T-cells for adoptive immunotherapy |
| US20030170238A1 (en) * | 2002-03-07 | 2003-09-11 | Gruenberg Micheal L. | Re-activated T-cells for adoptive immunotherapy |
| DE10230223A1 (de) | 2002-07-04 | 2004-01-22 | Tegenero Ag | Mikropartikel mit CD28-spezifischen monoklonalen Antikörpern |
| US7402431B2 (en) | 2004-03-01 | 2008-07-22 | Immunovative Therapies, Ltd. | T-cell therapy formulation |
| US7435592B2 (en) * | 2003-05-13 | 2008-10-14 | Immunovative Therapies, Ltd. | Compositions for allogeneic cell therapy |
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| US7592431B2 (en) | 2004-02-26 | 2009-09-22 | Immunovative Therapies, Ltd. | Biodegradable T-cell Activation device |
| US7678572B2 (en) | 2004-02-26 | 2010-03-16 | Immunovative Therapies, Ltd. | Methods for preparing T-cells for cell therapy |
| US7446099B2 (en) | 2004-02-27 | 2008-11-04 | Nitto Denko Corporation | Compositions and methods for biodegradable polymer-peptide mediated transfection |
| ES2635868T3 (es) | 2004-03-01 | 2017-10-05 | Immunovative Therapies, Ltd. | Método y composición de formulación de terapia celular |
| WO2005089127A2 (en) | 2004-03-05 | 2005-09-29 | The Trustees Of Columbia University In The City Of New York | Polymer-ceramic-hydrogel composite scaffold for osteochondral repair |
| TW200726474A (en) * | 2005-07-15 | 2007-07-16 | Cognate Therapeutics Inc | The immunophenotype and immunogenicity of human adipose derived cells |
| EP1792979A1 (en) * | 2005-12-01 | 2007-06-06 | Stiftung Caesar Center of Advanced European Studies and Research | Cell culture system for the enrichment and expansion of stem cells |
| EP2259798B1 (en) * | 2008-03-05 | 2013-12-11 | Baxter International Inc. | Surface-modified particles and methods for targeted drug delivery |
-
2012
- 2012-05-02 CA CA2838041A patent/CA2838041C/en active Active
- 2012-05-02 KR KR1020137032016A patent/KR102229108B1/ko active Active
- 2012-05-02 AU AU2012250794A patent/AU2012250794B2/en not_active Ceased
- 2012-05-02 SG SG2013081617A patent/SG194774A1/en unknown
- 2012-05-02 EP EP12779413.9A patent/EP2704741B1/en active Active
- 2012-05-02 CN CN201810178504.0A patent/CN108261423B/zh active Active
- 2012-05-02 PL PL12779413T patent/PL2704741T3/pl unknown
- 2012-05-02 ES ES12779413.9T patent/ES2648136T3/es active Active
- 2012-05-02 PH PH1/2013/502253A patent/PH12013502253A1/en unknown
- 2012-05-02 JP JP2014509383A patent/JP5934783B2/ja active Active
- 2012-05-02 BR BR112013028257-6A patent/BR112013028257B1/pt active IP Right Grant
- 2012-05-02 PT PT127794139T patent/PT2704741T/pt unknown
- 2012-05-02 HU HUE12779413A patent/HUE034995T2/en unknown
- 2012-05-02 WO PCT/US2012/036103 patent/WO2012151266A1/en not_active Ceased
- 2012-05-02 DK DK12779413.9T patent/DK2704741T3/da active
- 2012-05-02 US US13/581,895 patent/US10350242B2/en active Active
- 2012-05-02 KR KR1020147019539A patent/KR20140099328A/ko not_active Withdrawn
- 2012-05-02 CN CN201280032760.XA patent/CN103732247A/zh active Pending
- 2012-05-02 KR KR1020197020882A patent/KR102202460B1/ko active Active
-
2013
- 2013-10-31 IL IL229176A patent/IL229176B/en active IP Right Grant
-
2014
- 2014-12-26 JP JP2014266252A patent/JP6006288B2/ja active Active
-
2016
- 2016-09-07 JP JP2016174984A patent/JP6359059B2/ja active Active
-
2019
- 2019-06-06 US US16/433,659 patent/US11648273B2/en active Active
-
2023
- 2023-03-21 US US18/124,525 patent/US20230226112A1/en active Pending
- 2023-03-22 US US18/124,987 patent/US20230218672A1/en active Pending
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