JP2014517830A5 - - Google Patents
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- Publication number
- JP2014517830A5 JP2014517830A5 JP2014509383A JP2014509383A JP2014517830A5 JP 2014517830 A5 JP2014517830 A5 JP 2014517830A5 JP 2014509383 A JP2014509383 A JP 2014509383A JP 2014509383 A JP2014509383 A JP 2014509383A JP 2014517830 A5 JP2014517830 A5 JP 2014517830A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- composition
- living cells
- activated
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 80
- 238000000034 method Methods 0.000 claims 33
- 239000000872 buffer Substances 0.000 claims 27
- 230000000050 nutritive effect Effects 0.000 claims 27
- 239000000203 mixture Substances 0.000 claims 23
- 210000000447 Th1 cell Anatomy 0.000 claims 17
- 238000002360 preparation method Methods 0.000 claims 13
- 229960000074 biopharmaceutical Drugs 0.000 claims 7
- 238000009169 immunotherapy Methods 0.000 claims 7
- 108010029697 CD40 Ligand Proteins 0.000 claims 6
- 102100032937 CD40 ligand Human genes 0.000 claims 6
- 230000028327 secretion Effects 0.000 claims 5
- 102100037850 Interferon gamma Human genes 0.000 claims 4
- 108010074328 Interferon-gamma Proteins 0.000 claims 4
- 102000004127 Cytokines Human genes 0.000 claims 3
- 108090000695 Cytokines Proteins 0.000 claims 3
- 102000019034 Chemokines Human genes 0.000 claims 2
- 108010012236 Chemokines Proteins 0.000 claims 2
- 108010039471 Fas Ligand Protein Proteins 0.000 claims 2
- 102000001398 Granzyme Human genes 0.000 claims 2
- 108060005986 Granzyme Proteins 0.000 claims 2
- 102000004503 Perforin Human genes 0.000 claims 2
- 108010056995 Perforin Proteins 0.000 claims 2
- KHGNFPUMBJSZSM-UHFFFAOYSA-N Perforine Natural products COC1=C2CCC(O)C(CCC(C)(C)O)(OC)C2=NC2=C1C=CO2 KHGNFPUMBJSZSM-UHFFFAOYSA-N 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 102100031988 Tumor necrosis factor ligand superfamily member 6 Human genes 0.000 claims 2
- 239000007853 buffer solution Substances 0.000 claims 2
- 230000000139 costimulatory effect Effects 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 235000015097 nutrients Nutrition 0.000 claims 2
- 229930192851 perforin Natural products 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000001105 regulatory effect Effects 0.000 claims 2
- 230000032258 transport Effects 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161481991P | 2011-05-03 | 2011-05-03 | |
| US61/481,991 | 2011-05-03 | ||
| US201161528493P | 2011-08-29 | 2011-08-29 | |
| US61/528,493 | 2011-08-29 | ||
| US201161565225P | 2011-11-30 | 2011-11-30 | |
| US61/565,225 | 2011-11-30 | ||
| US201261582878P | 2012-01-04 | 2012-01-04 | |
| US61/582,878 | 2012-01-04 | ||
| PCT/US2012/036103 WO2012151266A1 (en) | 2011-05-03 | 2012-05-02 | Methods for handling biological drugs containing living cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014266252A Division JP6006288B2 (ja) | 2011-05-03 | 2014-12-26 | 柔軟性のある容器あるいは注射器 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517830A JP2014517830A (ja) | 2014-07-24 |
| JP2014517830A5 true JP2014517830A5 (enExample) | 2015-02-19 |
| JP5934783B2 JP5934783B2 (ja) | 2016-06-15 |
Family
ID=47108026
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014509383A Active JP5934783B2 (ja) | 2011-05-03 | 2012-05-02 | 生細胞を含む生物学的薬剤の取り扱い方法 |
| JP2014266252A Active JP6006288B2 (ja) | 2011-05-03 | 2014-12-26 | 柔軟性のある容器あるいは注射器 |
| JP2016174984A Active JP6359059B2 (ja) | 2011-05-03 | 2016-09-07 | 生細胞を含む生物学的薬剤の取り扱い方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014266252A Active JP6006288B2 (ja) | 2011-05-03 | 2014-12-26 | 柔軟性のある容器あるいは注射器 |
| JP2016174984A Active JP6359059B2 (ja) | 2011-05-03 | 2016-09-07 | 生細胞を含む生物学的薬剤の取り扱い方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10350242B2 (enExample) |
| EP (1) | EP2704741B1 (enExample) |
| JP (3) | JP5934783B2 (enExample) |
| KR (3) | KR102229108B1 (enExample) |
| CN (2) | CN103732247A (enExample) |
| AU (1) | AU2012250794B2 (enExample) |
| BR (1) | BR112013028257B1 (enExample) |
| CA (1) | CA2838041C (enExample) |
| DK (1) | DK2704741T3 (enExample) |
| ES (1) | ES2648136T3 (enExample) |
| HU (1) | HUE034995T2 (enExample) |
| IL (1) | IL229176B (enExample) |
| PH (1) | PH12013502253A1 (enExample) |
| PL (1) | PL2704741T3 (enExample) |
| PT (1) | PT2704741T (enExample) |
| SG (1) | SG194774A1 (enExample) |
| WO (1) | WO2012151266A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160095307A1 (en) | 2014-10-07 | 2016-04-07 | NuTech Medical, Inc. | Method and composition for hypothermic storage of placental tissue |
| WO2016075542A1 (en) * | 2014-11-11 | 2016-05-19 | Macrocure, Ltd. | Methods for extended storage of activated leukocyte compositions |
| JP6814593B2 (ja) * | 2016-10-14 | 2021-01-20 | 株式会社 バイオミメティクスシンパシーズ | 幹細胞及び投与システム |
| EP4578507A3 (en) | 2018-11-01 | 2025-11-12 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Compositions and methods for t cell engineering |
| CN118931967A (zh) * | 2018-12-07 | 2024-11-12 | 亘喜生物科技（上海）有限公司 | 用于免疫疗法的组合物和方法 |
| WO2020231968A1 (en) * | 2019-05-15 | 2020-11-19 | Stemcyte Inc. | High concentration cell packaging and shipping |
| JP7722390B2 (ja) | 2020-12-10 | 2025-08-13 | Ａｇｃ株式会社 | オキシアルキレン重合体、その製造方法、硬化性組成物、硬化物 |
| EP4306570A4 (en) | 2021-03-12 | 2025-03-05 | Agc Inc. | HARDENABLE COMPOSITION AND HARDENED PRODUCT |
| WO2023282298A1 (ja) | 2021-07-07 | 2023-01-12 | Ａｇｃ株式会社 | 硬化性組成物、硬化物、接着剤、及びシーリング材 |
| WO2023190640A1 (ja) * | 2022-03-30 | 2023-10-05 | 株式会社カネカ | 細胞投与用シリンジを調製する方法、及び細胞投与用シリンジを用いた細胞輸送方法 |
| DE112023002011T5 (de) | 2022-04-22 | 2025-02-20 | AGC Inc. | Aushärtbare zusammensetzung und ausgehärtetes produkt |
| JPWO2023204064A1 (enExample) | 2022-04-22 | 2023-10-26 | ||
| EP4516821A4 (en) | 2022-04-27 | 2026-04-29 | Agc Inc | PROCESS FOR PRODUCING AN ORGANIC POLYMER CONTAINING A REACTIVE SILICON GROUP |
| EP4516822A4 (en) | 2022-04-27 | 2026-04-29 | Agc Inc | PROCESS FOR PRODUCING AN ORGANIC POLYMER CONTAINING A REACTIVE SILICON GROUP |
| CN119301211A (zh) | 2022-06-03 | 2025-01-10 | Ａｇｃ株式会社 | 粘接剂组合物及物品 |
| WO2025143131A1 (ja) | 2023-12-27 | 2025-07-03 | Ａｇｃ株式会社 | 硬化性組成物及び硬化物 |
| WO2026009590A1 (ja) | 2024-07-05 | 2026-01-08 | Ａｇｃ株式会社 | 複合金属シアン化物錯体触媒、ポリエーテル化合物の製造方法、反応性ケイ素基を有するポリエーテル化合物の製造方法、ウレタン結合を有するポリエーテル化合物の製造方法、及び重合性不飽和基を有するポリエーテル化合物の製造方法 |
| WO2026009589A1 (ja) | 2024-07-05 | 2026-01-08 | Ａｇｃ株式会社 | 組成物、反応性ケイ素基を有するポリエーテル化合物の製造方法、ウレタン結合を有するポリエーテル化合物の製造方法、及び重合性不飽和基を有するポリエーテル化合物の製造方法 |
| WO2026014465A1 (ja) | 2024-07-12 | 2026-01-15 | Ａｇｃ株式会社 | ポリエーテル化合物の製造方法、反応性ケイ素基を有するポリエーテル化合物の製造方法、ウレタン結合を有するポリエーテル化合物の製造方法及び重合性不飽和基を有するポリエーテル化合物の製造方法 |
| EP4711399A1 (en) | 2024-07-12 | 2026-03-18 | Agc Inc. | Method for producing polyether compound, method for producing polyether compound having reactive silicon group, method for producing polyether compound having urethane bond, and method for producing polyether compound having polymerizable unsaturated group |
| EP4737503A1 (en) | 2024-07-12 | 2026-05-06 | Agc Inc. | Method for producing polyether compound, method for producing polyether compound having reactive silicon group, method for producing polyether compound having urethane bond, and method for producing polyether compound having polymerizable unsaturated group |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2439003A1 (fr) | 1978-10-20 | 1980-05-16 | Anvar | Nouvelles pieces d'osteosynthese, leur preparation et leur application |
| US5766920A (en) | 1982-08-11 | 1998-06-16 | Cellcor, Inc. | Ex vivo activation of immune cells |
| WO1988000970A2 (en) | 1986-08-08 | 1988-02-11 | Regents Of The University Of Minnesota | Method of culturing leukocytes |
| AU2635088A (en) | 1987-12-04 | 1989-06-08 | Du Pont Merck Pharmaceutical Company, The | Immobilized interleukin 2 and interleukin 2 containing a carboxyl-terminal extension |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US5126132A (en) | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| US5728388A (en) | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| US6204058B1 (en) | 1992-02-07 | 2001-03-20 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
| AU5729294A (en) | 1992-11-25 | 1994-06-22 | Tanox Biosystems, Inc. | Conjugates and constructs including anti-cd28 and anti-cd3 binding molecules |
| EP0726941B1 (en) | 1993-08-06 | 2002-04-03 | Epimmune Inc. | Methods for (ex vivo) therapy using peptide-loaded antigen presenting cells for the activation of ctl |
| IL107483A0 (en) | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| WO1996027392A1 (en) | 1995-03-08 | 1996-09-12 | The Scripps Research Institute | Antigen presenting system and methods for activation of t-cells |
| DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| IL126843A (en) | 1996-05-23 | 2007-06-17 | Scripps Research Inst | Mhc class ii antigen-presenting systems and methods for activating cd4+t cells in vitro |
| US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| ATE229810T1 (de) * | 1996-10-11 | 2003-01-15 | Univ California | Krebs immuntherapie unter verwendung von tumorzellen kombiniert mit lymphozytmischungen |
| WO1998024483A2 (en) | 1996-12-03 | 1998-06-11 | Osteobiologics, Inc. | Biodegradable polymeric film |
| CA2278847A1 (en) | 1997-01-31 | 1998-08-06 | Hemosol Inc. | Method for the production of selected lymphocytes |
| US7282198B2 (en) * | 1997-03-19 | 2007-10-16 | The University Of Arkansas For Medical Sciences | Immunotherapeutic methods targeted towards stratum corneum chymotryptic enzyme |
| EP1014897B1 (en) | 1997-05-30 | 2008-10-29 | Osteobiologics, Inc. | Fiber-reinforced, porous, biodegradable implant device |
| CA2309206A1 (en) | 1997-11-10 | 1999-05-20 | Arch Development Corporation | Methods for treatment of tumors and tumor cells using ex vivo activated t cells |
| AU4518400A (en) | 1999-07-12 | 2001-01-18 | Isotis B.V. | Sutures |
| US7112576B1 (en) | 1999-12-10 | 2006-09-26 | Regents Of The University Of Minnesota | Compositions and methods for cryopreservation of peripheral blood lymphocytes |
| US20030119185A1 (en) * | 2000-02-24 | 2003-06-26 | Xcyte Therapies, Inc. | Activation and expansion of cells |
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| WO2003053216A2 (en) | 2001-12-06 | 2003-07-03 | University Of Washington | Biodegradable, porous structures useful for growing living tissue, and methods of manufacture |
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| US7446099B2 (en) | 2004-02-27 | 2008-11-04 | Nitto Denko Corporation | Compositions and methods for biodegradable polymer-peptide mediated transfection |
| EP1749090B1 (en) | 2004-03-01 | 2017-05-17 | Immunovative Therapies, Ltd. | Cell therapy formulation method and composition |
| WO2005089127A2 (en) | 2004-03-05 | 2005-09-29 | The Trustees Of Columbia University In The City Of New York | Polymer-ceramic-hydrogel composite scaffold for osteochondral repair |
| TW200726474A (en) * | 2005-07-15 | 2007-07-16 | Cognate Therapeutics Inc | The immunophenotype and immunogenicity of human adipose derived cells |
| EP1792979A1 (en) | 2005-12-01 | 2007-06-06 | Stiftung Caesar Center of Advanced European Studies and Research | Cell culture system for the enrichment and expansion of stem cells |
| RU2496482C2 (ru) * | 2008-03-05 | 2013-10-27 | Бакстер Интернэшнл Инк. | Композиции и способы для доставки лекарственных средств |
-
2012
- 2012-05-02 KR KR1020137032016A patent/KR102229108B1/ko active Active
- 2012-05-02 AU AU2012250794A patent/AU2012250794B2/en not_active Ceased
- 2012-05-02 DK DK12779413.9T patent/DK2704741T3/da active
- 2012-05-02 KR KR1020147019539A patent/KR20140099328A/ko not_active Withdrawn
- 2012-05-02 KR KR1020197020882A patent/KR102202460B1/ko active Active
- 2012-05-02 JP JP2014509383A patent/JP5934783B2/ja active Active
- 2012-05-02 US US13/581,895 patent/US10350242B2/en active Active
- 2012-05-02 PH PH1/2013/502253A patent/PH12013502253A1/en unknown
- 2012-05-02 BR BR112013028257-6A patent/BR112013028257B1/pt active IP Right Grant
- 2012-05-02 CA CA2838041A patent/CA2838041C/en active Active
- 2012-05-02 CN CN201280032760.XA patent/CN103732247A/zh active Pending
- 2012-05-02 HU HUE12779413A patent/HUE034995T2/en unknown
- 2012-05-02 EP EP12779413.9A patent/EP2704741B1/en active Active
- 2012-05-02 SG SG2013081617A patent/SG194774A1/en unknown
- 2012-05-02 WO PCT/US2012/036103 patent/WO2012151266A1/en not_active Ceased
- 2012-05-02 PT PT127794139T patent/PT2704741T/pt unknown
- 2012-05-02 PL PL12779413T patent/PL2704741T3/pl unknown
- 2012-05-02 CN CN201810178504.0A patent/CN108261423B/zh active Active
- 2012-05-02 ES ES12779413.9T patent/ES2648136T3/es active Active
-
2013
- 2013-10-31 IL IL229176A patent/IL229176B/en active IP Right Grant
-
2014
- 2014-12-26 JP JP2014266252A patent/JP6006288B2/ja active Active
-
2016
- 2016-09-07 JP JP2016174984A patent/JP6359059B2/ja active Active
-
2019
- 2019-06-06 US US16/433,659 patent/US11648273B2/en active Active
-
2023
- 2023-03-21 US US18/124,525 patent/US20230226112A1/en active Pending
- 2023-03-22 US US18/124,987 patent/US20230218672A1/en active Pending
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