JP2014516924A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014516924A5 JP2014516924A5 JP2014504013A JP2014504013A JP2014516924A5 JP 2014516924 A5 JP2014516924 A5 JP 2014516924A5 JP 2014504013 A JP2014504013 A JP 2014504013A JP 2014504013 A JP2014504013 A JP 2014504013A JP 2014516924 A5 JP2014516924 A5 JP 2014516924A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- viscosity
- less
- citrate
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161473121P | 2011-04-07 | 2011-04-07 | |
| US61/473,121 | 2011-04-07 | ||
| PCT/US2012/032462 WO2012138958A1 (en) | 2011-04-07 | 2012-04-06 | Formulations with reduced viscosity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014516924A JP2014516924A (ja) | 2014-07-17 |
| JP2014516924A5 true JP2014516924A5 (https=) | 2016-01-28 |
Family
ID=46969561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014504013A Pending JP2014516924A (ja) | 2011-04-07 | 2012-04-06 | 粘度が低減された処方物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20140023655A1 (https=) |
| EP (2) | EP3058952A1 (https=) |
| JP (1) | JP2014516924A (https=) |
| KR (1) | KR20140018966A (https=) |
| CN (1) | CN103596585A (https=) |
| AU (2) | AU2012240050B2 (https=) |
| BR (1) | BR112013025866A2 (https=) |
| CA (1) | CA2832556A1 (https=) |
| EA (1) | EA201391488A1 (https=) |
| IL (1) | IL228591A0 (https=) |
| SG (1) | SG193963A1 (https=) |
| WO (1) | WO2012138958A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH12012501364A1 (en) * | 2010-01-15 | 2012-10-22 | Amgen K A Inc | Antibody formulation and therapeutic regimens |
| CN108771655A (zh) | 2011-10-28 | 2018-11-09 | 诚信生物公司 | 含有氨基酸的蛋白质制剂 |
| FR2994390B1 (fr) | 2012-08-10 | 2014-08-15 | Adocia | Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee |
| WO2014141149A1 (en) * | 2013-03-15 | 2014-09-18 | Glaxosmithkline Intellectual Property (No.2) Limited | Formulations with reduced viscosity |
| WO2014169153A1 (en) * | 2013-04-10 | 2014-10-16 | Echogen, Inc. | Peptide complexes and therapeutic uses |
| JP6179939B2 (ja) * | 2013-07-09 | 2017-08-16 | 国立大学法人 筑波大学 | 高濃度γグロブリン製剤の粘度低下方法 |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| AU2015325055B2 (en) | 2014-10-01 | 2021-02-25 | Eagle Biologics, Inc. | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| EP3804747A1 (en) * | 2015-01-18 | 2021-04-14 | Gloriana Therapeutics, Inc. | Therapeutic protein formulations |
| KR20180037275A (ko) | 2015-08-24 | 2018-04-11 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | 생물제약 조성물 |
| US11603407B2 (en) * | 2017-04-06 | 2023-03-14 | Regeneron Pharmaceuticals, Inc. | Stable antibody formulation |
| US10646569B2 (en) | 2017-05-16 | 2020-05-12 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
| AU2020251627A1 (en) | 2019-03-29 | 2021-11-11 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition containing antibody against IL-5 and use thereof |
| JP2023533704A (ja) * | 2020-07-13 | 2023-08-04 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 高濃度タンパク質製剤用の粘度低減賦形剤及びそれらの組み合わせ |
| KR20230167968A (ko) * | 2022-06-03 | 2023-12-12 | 주식회사 녹십자홀딩스 | 점도 감소 부형제 조성물 및 이를 포함하는 저점도 고농축 단백질 제형 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57106673A (en) | 1980-12-24 | 1982-07-02 | Chugai Pharmaceut Co Ltd | Dibenzo(b,f)(1,4)oxazepin derivative |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5747447A (en) * | 1992-04-30 | 1998-05-05 | Cor Therapeutics | Stable polypeptide composition |
| IL127127A0 (en) | 1998-11-18 | 1999-09-22 | Peptor Ltd | Small functional units of antibody heavy chain variable regions |
| AU2002213441B2 (en) * | 2000-10-12 | 2006-10-26 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
| PT1419179E (pt) | 2001-08-10 | 2010-03-16 | Univ Aberdeen | Domínios de ligação de antigenes |
| CA2503946C (en) * | 2002-11-01 | 2016-08-16 | Glaxosmithkline Biologicals S.A. | Drying process |
| WO2004060343A1 (en) * | 2002-12-31 | 2004-07-22 | Nektar Therapeutics | Antibody-containing particles and compositions |
| MXPA05010555A (es) * | 2003-04-04 | 2006-03-09 | Genentech Inc | Formulaciones de proteina y anticuerpo de alta concentracion. |
| EP1532983A1 (en) * | 2003-11-18 | 2005-05-25 | ZLB Bioplasma AG | Immunoglobulin preparations having increased stability |
| BRPI0620316A2 (pt) * | 2005-12-21 | 2011-11-08 | Wyeth Corp | formulações de proteìnas com viscosidades reduzida e seus usos |
| WO2007074880A1 (ja) * | 2005-12-28 | 2007-07-05 | Chugai Seiyaku Kabushiki Kaisha | 抗体含有安定化製剤 |
| CA2790018C (en) * | 2006-12-21 | 2015-02-03 | Amgen Inc. | Formulations |
| EP2205280B1 (en) * | 2007-09-27 | 2019-09-04 | Amgen Inc. | Pharmaceutical formulations |
| US20090148905A1 (en) * | 2007-11-30 | 2009-06-11 | Claire Ashman | Antigen-binding constructs |
| PE20091174A1 (es) * | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| PH12012501364A1 (en) * | 2010-01-15 | 2012-10-22 | Amgen K A Inc | Antibody formulation and therapeutic regimens |
| WO2011095543A1 (en) * | 2010-02-04 | 2011-08-11 | Csl Behring Ag | Immunoglobulin preparation |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| EA201391489A1 (ru) * | 2011-04-07 | 2014-02-28 | ГЛЭКСОСМИТКЛАЙН ЭлЭлСи | Композиции со сниженной вязкостью |
-
2012
- 2012-04-06 SG SG2013072426A patent/SG193963A1/en unknown
- 2012-04-06 BR BR112013025866A patent/BR112013025866A2/pt not_active IP Right Cessation
- 2012-04-06 KR KR1020137029163A patent/KR20140018966A/ko not_active Withdrawn
- 2012-04-06 EA EA201391488A patent/EA201391488A1/ru unknown
- 2012-04-06 WO PCT/US2012/032462 patent/WO2012138958A1/en not_active Ceased
- 2012-04-06 CA CA2832556A patent/CA2832556A1/en not_active Abandoned
- 2012-04-06 CN CN201280026486.5A patent/CN103596585A/zh active Pending
- 2012-04-06 EP EP16154327.7A patent/EP3058952A1/en not_active Withdrawn
- 2012-04-06 EP EP12768307.6A patent/EP2694100A4/en not_active Withdrawn
- 2012-04-06 US US14/110,182 patent/US20140023655A1/en not_active Abandoned
- 2012-04-06 AU AU2012240050A patent/AU2012240050B2/en not_active Ceased
- 2012-04-06 JP JP2014504013A patent/JP2014516924A/ja active Pending
-
2013
- 2013-09-29 IL IL228591A patent/IL228591A0/en unknown
-
2016
- 2016-04-14 AU AU2016202355A patent/AU2016202355A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014516924A5 (https=) | ||
| JP2014510152A5 (https=) | ||
| KR102462041B1 (ko) | 암 치료용 담체－ｐｄ－ｌ１ 결합제 조성물 | |
| RU2020123963A (ru) | Стабилизированные препараты, содержащие антитела против ngf | |
| ES2885815T3 (es) | Nuevo formato biespecífico adecuado para su uso en el cribado de alto rendimiento | |
| JP2022087255A (ja) | キャリア結合剤組成物およびそれを作製および使用する方法 | |
| JP2021059593A (ja) | 担体および抗体からなる組成物およびその製造および使用方法 | |
| RU2013155695A (ru) | Препараты антител против с-мет | |
| JP2024054251A (ja) | ヒト成長分化因子１５（ｇｄｆ－１５）の阻害剤及び免疫チェックポイントブロッカーを使用する併用療法 | |
| RU2011142184A (ru) | Фармацевтический состав, содержащий молекулы антител с улучшенными свойствами | |
| NZ627859A (en) | Stabilized formulations containing anti-ang2 antibodies | |
| JP2018521135A5 (https=) | ||
| RU2012131671A (ru) | Способ полипептидной модификации для очистки полипептидных мультимеров | |
| JP2014522843A5 (https=) | ||
| NZ630020A (en) | Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof | |
| JP2020537520A5 (https=) | ||
| RU2019102009A (ru) | Специфические антитела к pd-l1 и способы их применения | |
| UA107211C2 (uk) | Стабілізовані склади, які містять антитіла до рецептора інтерлейкіну 6 (il-6r) | |
| US20230203152A1 (en) | Engineered anti-il-2 antibodies | |
| ME02807B (me) | HUMANI ANTIGEN-VEZUJUĆI PROTEINI KOJI SE VEZUJU ZA BETA-KLOTHO, FGF RECEPTORE l NJIHOVE KOMPLEKSE | |
| RU2016129624A (ru) | Биспецифичные антитела против гаптена/против рецептора гематоэнцефалического барьера, их комплексы и их применение в качестве челноков гематоэнцефалического барьера | |
| RU2534564C3 (ru) | Мультиспецифическая связывающая антиген молекула, которая обладает альтернативной функцией к функции фактора свертывания крови viii | |
| JP2013543505A5 (https=) | ||
| RU2015123476A (ru) | Стабильные составы антител против рецептора программируемой смерти pd-1 человека и относящиеся к ним способы лечения | |
| JP2014502955A5 (https=) |