JP2014516543A5 - - Google Patents
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- JP2014516543A5 JP2014516543A5 JP2014513083A JP2014513083A JP2014516543A5 JP 2014516543 A5 JP2014516543 A5 JP 2014516543A5 JP 2014513083 A JP2014513083 A JP 2014513083A JP 2014513083 A JP2014513083 A JP 2014513083A JP 2014516543 A5 JP2014516543 A5 JP 2014516543A5
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- JP
- Japan
- Prior art keywords
- biomarker
- cancer
- expression
- sample
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000090 biomarker Substances 0.000 claims description 68
- 206010028980 Neoplasm Diseases 0.000 claims description 58
- 238000000034 method Methods 0.000 claims description 57
- 201000011510 cancer Diseases 0.000 claims description 55
- 150000007523 nucleic acids Chemical class 0.000 claims description 33
- 102000039446 nucleic acids Human genes 0.000 claims description 33
- 108020004707 nucleic acids Proteins 0.000 claims description 33
- 230000000295 complement effect Effects 0.000 claims description 24
- 238000004393 prognosis Methods 0.000 claims description 21
- 239000002773 nucleotide Substances 0.000 claims description 14
- 125000003729 nucleotide group Chemical group 0.000 claims description 14
- 238000009396 hybridization Methods 0.000 claims description 10
- 238000010837 poor prognosis Methods 0.000 claims description 8
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims description 5
- 208000003837 Second Primary Neoplasms Diseases 0.000 claims description 5
- 201000005202 lung cancer Diseases 0.000 claims description 5
- 208000020816 lung neoplasm Diseases 0.000 claims description 5
- 238000002512 chemotherapy Methods 0.000 claims description 3
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims description 3
- 238000001959 radiotherapy Methods 0.000 claims description 3
- 238000003757 reverse transcription PCR Methods 0.000 claims description 3
- 238000001356 surgical procedure Methods 0.000 claims description 3
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims description 3
- 238000005259 measurement Methods 0.000 claims description 2
- 238000002493 microarray Methods 0.000 claims description 2
- 230000002596 correlated effect Effects 0.000 claims 3
- 239000000523 sample Substances 0.000 description 21
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 239000013610 patient sample Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201100416 | 2011-06-01 | ||
| DKPA201100416 | 2011-06-01 | ||
| PCT/EP2012/002332 WO2012163541A1 (en) | 2011-06-01 | 2012-06-01 | Methods and devices for prognosis of cancer relapse |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014516543A JP2014516543A (ja) | 2014-07-17 |
| JP2014516543A5 true JP2014516543A5 (cg-RX-API-DMAC7.html) | 2015-07-16 |
| JP6039656B2 JP6039656B2 (ja) | 2016-12-07 |
Family
ID=46208426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014513083A Expired - Fee Related JP6039656B2 (ja) | 2011-06-01 | 2012-06-01 | 癌再発の予後予測のための方法および装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140106986A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2714927B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6039656B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN103930563B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012265177B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2836836A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012163541A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| US10016620B2 (en) * | 2010-02-04 | 2018-07-10 | Procept Biorobotics Incorporation | Tissue sampling and cancer treatment apparatus |
| WO2011135459A2 (en) | 2010-04-29 | 2011-11-03 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy |
| US10392667B2 (en) | 2013-06-07 | 2019-08-27 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients |
| CN103740845B (zh) * | 2014-01-28 | 2016-04-13 | 厦门大学附属中山医院 | 基于AllGlo探针荧光定量PCR的hsa-miR-513b检测试剂盒及其检测方法 |
| JP6657125B2 (ja) * | 2014-06-24 | 2020-03-04 | プロセプト バイオロボティクス コーポレイション | 組織サンプリングおよび癌処置方法および装置 |
| DK3198035T3 (da) | 2014-09-26 | 2023-01-30 | Allarity Therapeutics Europe ApS | Fremgangsmåder til forudsigelse af medicinrespons |
| EP3325667B1 (en) * | 2015-07-21 | 2020-11-11 | Guardant Health, Inc. | Locked nucleic acids for capturing fusion genes |
| US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2018202878A1 (en) | 2017-05-16 | 2018-12-06 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| CN109971851A (zh) * | 2019-01-22 | 2019-07-05 | 宁波大学 | MiR-125b-2-3p作为鉴别诊断肾癌亚型的分子标志物及其在肿瘤转移中的用途 |
| CN110079603A (zh) * | 2019-06-14 | 2019-08-02 | 福建省肿瘤医院（福建省肿瘤研究所、福建省癌症防治中心） | 一种鼻咽癌标志物的检测引物、探针及其应用 |
| JP7299765B2 (ja) * | 2019-06-14 | 2023-06-28 | 株式会社東芝 | マイクロｒｎａ測定方法およびキット |
| CN110408706B (zh) * | 2019-08-30 | 2023-04-11 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 一种评估鼻咽癌复发的生物标志物及其应用 |
| CN111554402A (zh) * | 2020-04-24 | 2020-08-18 | 山东省立医院 | 基于机器学习的原发性肝癌术后复发风险预测方法及系统 |
| CN111564177B (zh) * | 2020-05-22 | 2023-03-31 | 四川大学华西医院 | 基于dna甲基化的早期非小细胞肺癌复发模型构建方法 |
| CN111778341B (zh) * | 2020-07-28 | 2023-07-04 | 广东医科大学 | 一种活动性肺结核的生物标志物及其应用 |
| CN115261464A (zh) * | 2021-07-06 | 2022-11-01 | 西北工业大学 | 一组消化道泛癌诊疗用mRNA靶点 |
| US20240404707A1 (en) * | 2021-09-02 | 2024-12-05 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Machine learning-based systems and methods for predicting liver cancer recurrence in liver transplant patients |
| CN114990229B (zh) * | 2022-06-20 | 2023-01-03 | 广东医科大学附属医院 | 一种嗜碱性粒细胞活化相关的生物标志物及其应用 |
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| US5766960A (en) | 1987-07-27 | 1998-06-16 | Australian Membrane And Biotechnology Research Institute | Receptor membranes |
| GB8822228D0 (en) | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
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| US5936731A (en) | 1991-02-22 | 1999-08-10 | Applied Spectral Imaging Ltd. | Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting |
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| AU687535B2 (en) | 1994-03-16 | 1998-02-26 | Gen-Probe Incorporated | Isothermal strand displacement nucleic acid amplification |
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-
2012
- 2012-06-01 EP EP12725624.6A patent/EP2714927B1/en not_active Not-in-force
- 2012-06-01 CA CA2836836A patent/CA2836836A1/en not_active Abandoned
- 2012-06-01 JP JP2014513083A patent/JP6039656B2/ja not_active Expired - Fee Related
- 2012-06-01 CN CN201280038428.4A patent/CN103930563B/zh not_active Expired - Fee Related
- 2012-06-01 US US14/119,008 patent/US20140106986A1/en not_active Abandoned
- 2012-06-01 AU AU2012265177A patent/AU2012265177B2/en not_active Ceased
- 2012-06-01 WO PCT/EP2012/002332 patent/WO2012163541A1/en not_active Ceased
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