JP2014515821A5 - - Google Patents
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- Publication number
- JP2014515821A5 JP2014515821A5 JP2014501759A JP2014501759A JP2014515821A5 JP 2014515821 A5 JP2014515821 A5 JP 2014515821A5 JP 2014501759 A JP2014501759 A JP 2014501759A JP 2014501759 A JP2014501759 A JP 2014501759A JP 2014515821 A5 JP2014515821 A5 JP 2014515821A5
- Authority
- JP
- Japan
- Prior art keywords
- cadherin
- biological
- combination
- cells
- prognosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000090 biomarker Substances 0.000 claims 33
- 102100032912 CD44 antigen Human genes 0.000 claims 30
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 30
- 102000000905 Cadherin Human genes 0.000 claims 23
- 108050007957 Cadherin Proteins 0.000 claims 23
- 101000610551 Homo sapiens Prominin-1 Proteins 0.000 claims 23
- 102100040120 Prominin-1 Human genes 0.000 claims 23
- 210000004027 cell Anatomy 0.000 claims 21
- 206010006187 Breast cancer Diseases 0.000 claims 17
- 208000026310 Breast neoplasm Diseases 0.000 claims 17
- 238000004393 prognosis Methods 0.000 claims 17
- 102100022595 Broad substrate specificity ATP-binding cassette transporter ABCG2 Human genes 0.000 claims 16
- 108010090306 Member 2 Subfamily G ATP Binding Cassette Transporter Proteins 0.000 claims 16
- 238000000034 method Methods 0.000 claims 16
- 102000015694 estrogen receptors Human genes 0.000 claims 10
- 102100028163 ATP-binding cassette sub-family C member 4 Human genes 0.000 claims 9
- 102000015735 Beta-catenin Human genes 0.000 claims 9
- 108060000903 Beta-catenin Proteins 0.000 claims 9
- 101000986629 Homo sapiens ATP-binding cassette sub-family C member 4 Proteins 0.000 claims 9
- 102100035423 POU domain, class 5, transcription factor 1 Human genes 0.000 claims 9
- 101710126211 POU domain, class 5, transcription factor 1 Proteins 0.000 claims 9
- 102000003998 progesterone receptors Human genes 0.000 claims 9
- 238000010186 staining Methods 0.000 claims 9
- 108010038795 estrogen receptors Proteins 0.000 claims 8
- 108090000468 progesterone receptors Proteins 0.000 claims 7
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 6
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 6
- 239000000523 sample Substances 0.000 claims 6
- 239000012472 biological sample Substances 0.000 claims 5
- 239000003960 organic solvent Substances 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 3
- 238000002991 immunohistochemical analysis Methods 0.000 claims 3
- 101000882584 Homo sapiens Estrogen receptor Proteins 0.000 claims 2
- 101000574060 Homo sapiens Progesterone receptor Proteins 0.000 claims 2
- 210000000170 cell membrane Anatomy 0.000 claims 2
- 210000003855 cell nucleus Anatomy 0.000 claims 2
- 230000000875 corresponding effect Effects 0.000 claims 2
- 210000000805 cytoplasm Anatomy 0.000 claims 2
- 229940011871 estrogen Drugs 0.000 claims 2
- 239000000262 estrogen Substances 0.000 claims 2
- 238000003364 immunohistochemistry Methods 0.000 claims 2
- 210000000633 nuclear envelope Anatomy 0.000 claims 2
- 102000005962 receptors Human genes 0.000 claims 2
- 108020003175 receptors Proteins 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000001638 cerebellum Anatomy 0.000 claims 1
- 239000007795 chemical reaction product Substances 0.000 claims 1
- 238000007796 conventional method Methods 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 230000002055 immunohistochemical effect Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 108010090388 progesterone receptor A Proteins 0.000 claims 1
- 239000000376 reactant Substances 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
- 238000011282 treatment Methods 0.000 claims 1
- 239000008096 xylene Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2835/CHE/2010 | 2011-03-27 | ||
| IN2835CH2010 | 2011-03-27 | ||
| PCT/IB2012/051427 WO2012131564A1 (en) | 2011-03-27 | 2012-03-26 | Markers for identifying tumor cells, methods and kit thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014515821A JP2014515821A (ja) | 2014-07-03 |
| JP2014515821A5 true JP2014515821A5 (enExample) | 2015-05-07 |
Family
ID=46877646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014501759A Pending JP2014515821A (ja) | 2011-03-27 | 2012-03-26 | 腫瘍細胞を同定するためのマーカー、その方法およびキット |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8772455B2 (enExample) |
| EP (1) | EP2691776A4 (enExample) |
| JP (1) | JP2014515821A (enExample) |
| KR (1) | KR101621036B1 (enExample) |
| CN (1) | CN103562723B (enExample) |
| AU (1) | AU2012235767B2 (enExample) |
| SG (1) | SG193630A1 (enExample) |
| WO (1) | WO2012131564A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105209070A (zh) | 2013-03-15 | 2015-12-30 | 瓦里安医疗系统公司 | 用于放射疗法的生物标志物 |
| ES2728305T3 (es) * | 2013-04-29 | 2019-10-23 | Ogd2 Pharma | Uso como diana del gangliosido GD2 O-acetilado como una nueva estrategia terapéutica y de diagnóstico para cáncer de células madre cancerosas |
| US10839509B2 (en) | 2015-07-10 | 2020-11-17 | 3Scan Inc. | Spatial multiplexing of histological stains |
| FR3044680B1 (fr) * | 2015-12-02 | 2017-12-22 | Univ Limoges | Methode de detection de cellules souches cancereuses |
| ES2882875T3 (es) * | 2016-05-24 | 2021-12-03 | Oncostem Pte Ltd | Método de pronóstico y predicción de la recurrencia del cáncer de mama, marcadores empleados en el mismo y kit del mismo |
| CN106053172B (zh) * | 2016-06-03 | 2018-10-30 | 浙江世纪康大医疗科技股份有限公司 | 一种edta抗原修复液 |
| US10166406B2 (en) | 2017-02-24 | 2019-01-01 | Varian Medical Systems International Ag | Radiation treatment planning and delivery using collision free regions |
| CN115429881A (zh) * | 2022-09-02 | 2022-12-06 | 中国医学科学院基础医学研究所 | 铁螯合剂治疗β-连环蛋白活化突变的肿瘤 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2558366A1 (en) * | 2004-02-23 | 2005-09-01 | Erasmus Universiteit Rotterdam | Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling |
| WO2006016110A1 (en) * | 2004-08-10 | 2006-02-16 | University College Cardiff Consultants Limited | Methods and kit for the prognosis of breast cancer |
| WO2007075672A2 (en) * | 2005-12-23 | 2007-07-05 | Lankenau Institute For Medical Research | Prognostic cancer markers |
| CN101583624B (zh) * | 2006-09-29 | 2012-11-21 | 昂考梅德药品有限公司 | 用于诊断和治疗癌症的组合物及其用途 |
| US7750124B2 (en) | 2006-09-29 | 2010-07-06 | Oncomed Pharmaceuticals, Inc. | Anti-human DLL4 antibodies and compositions |
| US7968169B2 (en) * | 2007-08-07 | 2011-06-28 | The Boeing Company | Compound contoured composite beams and fabrication methods |
| CA2723648A1 (en) * | 2008-04-10 | 2009-10-15 | Piyush Gupta | Methods for identification and use of agents targeting cancer stem cells |
| JPWO2011007853A1 (ja) * | 2009-07-14 | 2012-12-27 | リンク・ジェノミクス株式会社 | 癌特異的アイソフォームに対するモノクローナル抗体 |
| US20130059903A1 (en) * | 2010-03-12 | 2013-03-07 | The Johns Hopkins University | Compositions and Methods for Characterizing Breast Cancer |
-
2012
- 2012-03-26 AU AU2012235767A patent/AU2012235767B2/en active Active
- 2012-03-26 EP EP12765275.8A patent/EP2691776A4/en not_active Withdrawn
- 2012-03-26 WO PCT/IB2012/051427 patent/WO2012131564A1/en not_active Ceased
- 2012-03-26 KR KR1020137028327A patent/KR101621036B1/ko active Active
- 2012-03-26 JP JP2014501759A patent/JP2014515821A/ja active Pending
- 2012-03-26 SG SG2013072483A patent/SG193630A1/en unknown
- 2012-03-26 CN CN201280021095.4A patent/CN103562723B/zh active Active
- 2012-03-27 US US13/431,919 patent/US8772455B2/en active Active
-
2014
- 2014-06-13 US US14/304,432 patent/US20140295459A1/en not_active Abandoned
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