KR101621036B1 - 종양 세포를 동정하기 위한 마커, 그의 방법 및 키트 - Google Patents

종양 세포를 동정하기 위한 마커, 그의 방법 및 키트 Download PDF

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KR101621036B1
KR101621036B1 KR1020137028327A KR20137028327A KR101621036B1 KR 101621036 B1 KR101621036 B1 KR 101621036B1 KR 1020137028327 A KR1020137028327 A KR 1020137028327A KR 20137028327 A KR20137028327 A KR 20137028327A KR 101621036 B1 KR101621036 B1 KR 101621036B1
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marker
cells
prognosis
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receptor
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KR20140015500A (ko
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만지리 바크레
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온코스템 다이아그노틱스 (모리셔스) 프라이빗 리미티드
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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KR1020137028327A 2011-03-27 2012-03-26 종양 세포를 동정하기 위한 마커, 그의 방법 및 키트 Active KR101621036B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2835/CHE/2010 2011-03-27
IN2835CH2010 2011-03-27
PCT/IB2012/051427 WO2012131564A1 (en) 2011-03-27 2012-03-26 Markers for identifying tumor cells, methods and kit thereof

Publications (2)

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KR20140015500A KR20140015500A (ko) 2014-02-06
KR101621036B1 true KR101621036B1 (ko) 2016-05-13

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US (2) US8772455B2 (enExample)
EP (1) EP2691776A4 (enExample)
JP (1) JP2014515821A (enExample)
KR (1) KR101621036B1 (enExample)
CN (1) CN103562723B (enExample)
AU (1) AU2012235767B2 (enExample)
SG (1) SG193630A1 (enExample)
WO (1) WO2012131564A1 (enExample)

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CN105209070A (zh) 2013-03-15 2015-12-30 瓦里安医疗系统公司 用于放射疗法的生物标志物
ES2728305T3 (es) * 2013-04-29 2019-10-23 Ogd2 Pharma Uso como diana del gangliosido GD2 O-acetilado como una nueva estrategia terapéutica y de diagnóstico para cáncer de células madre cancerosas
US10839509B2 (en) 2015-07-10 2020-11-17 3Scan Inc. Spatial multiplexing of histological stains
FR3044680B1 (fr) * 2015-12-02 2017-12-22 Univ Limoges Methode de detection de cellules souches cancereuses
ES2882875T3 (es) * 2016-05-24 2021-12-03 Oncostem Pte Ltd Método de pronóstico y predicción de la recurrencia del cáncer de mama, marcadores empleados en el mismo y kit del mismo
CN106053172B (zh) * 2016-06-03 2018-10-30 浙江世纪康大医疗科技股份有限公司 一种edta抗原修复液
US10166406B2 (en) 2017-02-24 2019-01-01 Varian Medical Systems International Ag Radiation treatment planning and delivery using collision free regions
CN115429881A (zh) * 2022-09-02 2022-12-06 中国医学科学院基础医学研究所 铁螯合剂治疗β-连环蛋白活化突变的肿瘤

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008042236A2 (en) 2006-09-29 2008-04-10 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer

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Publication number Priority date Publication date Assignee Title
CA2558366A1 (en) * 2004-02-23 2005-09-01 Erasmus Universiteit Rotterdam Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling
WO2006016110A1 (en) * 2004-08-10 2006-02-16 University College Cardiff Consultants Limited Methods and kit for the prognosis of breast cancer
WO2007075672A2 (en) * 2005-12-23 2007-07-05 Lankenau Institute For Medical Research Prognostic cancer markers
CN101583624B (zh) * 2006-09-29 2012-11-21 昂考梅德药品有限公司 用于诊断和治疗癌症的组合物及其用途
US7968169B2 (en) * 2007-08-07 2011-06-28 The Boeing Company Compound contoured composite beams and fabrication methods
CA2723648A1 (en) * 2008-04-10 2009-10-15 Piyush Gupta Methods for identification and use of agents targeting cancer stem cells
JPWO2011007853A1 (ja) * 2009-07-14 2012-12-27 リンク・ジェノミクス株式会社 癌特異的アイソフォームに対するモノクローナル抗体
US20130059903A1 (en) * 2010-03-12 2013-03-07 The Johns Hopkins University Compositions and Methods for Characterizing Breast Cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008042236A2 (en) 2006-09-29 2008-04-10 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Breast Cancer Research, 2008,10권,R53.
Chinese Medical Journal, 2009,122권,22호,2763-69면.

Also Published As

Publication number Publication date
JP2014515821A (ja) 2014-07-03
WO2012131564A1 (en) 2012-10-04
CN103562723A (zh) 2014-02-05
US8772455B2 (en) 2014-07-08
CN103562723B (zh) 2017-04-26
SG193630A1 (en) 2013-10-30
EP2691776A4 (en) 2015-04-15
KR20140015500A (ko) 2014-02-06
EP2691776A1 (en) 2014-02-05
AU2012235767B2 (en) 2016-02-04
AU2012235767A1 (en) 2013-11-07
US20120244556A1 (en) 2012-09-27
US20140295459A1 (en) 2014-10-02

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