JP2014515737A - HOClの安定な組成物、その製造方法、およびその使用 - Google Patents
HOClの安定な組成物、その製造方法、およびその使用 Download PDFInfo
- Publication number
- JP2014515737A JP2014515737A JP2013558492A JP2013558492A JP2014515737A JP 2014515737 A JP2014515737 A JP 2014515737A JP 2013558492 A JP2013558492 A JP 2013558492A JP 2013558492 A JP2013558492 A JP 2013558492A JP 2014515737 A JP2014515737 A JP 2014515737A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- composition
- solution
- chloride
- calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 124
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical group ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 title claims abstract description 122
- 238000000034 method Methods 0.000 title claims description 37
- 238000004519 manufacturing process Methods 0.000 title claims description 11
- 230000008569 process Effects 0.000 title description 9
- 239000000243 solution Substances 0.000 claims abstract description 104
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims abstract description 50
- 239000007864 aqueous solution Substances 0.000 claims abstract description 21
- 239000003381 stabilizer Substances 0.000 claims abstract description 12
- 239000008247 solid mixture Substances 0.000 claims abstract description 5
- 239000000460 chlorine Substances 0.000 claims description 60
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 57
- 229910052801 chlorine Inorganic materials 0.000 claims description 55
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 claims description 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 41
- 229910052736 halogen Inorganic materials 0.000 claims description 32
- 150000002367 halogens Chemical class 0.000 claims description 32
- 229910001868 water Inorganic materials 0.000 claims description 30
- 239000002253 acid Substances 0.000 claims description 29
- ZKQDCIXGCQPQNV-UHFFFAOYSA-N Calcium hypochlorite Chemical group [Ca+2].Cl[O-].Cl[O-] ZKQDCIXGCQPQNV-UHFFFAOYSA-N 0.000 claims description 28
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 18
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 14
- 239000011575 calcium Substances 0.000 claims description 14
- 229910052791 calcium Inorganic materials 0.000 claims description 14
- -1 chelants Substances 0.000 claims description 14
- 239000007787 solid Substances 0.000 claims description 14
- 239000000645 desinfectant Substances 0.000 claims description 10
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 9
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 9
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 9
- 239000001110 calcium chloride Substances 0.000 claims description 9
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 9
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 8
- 239000003242 anti bacterial agent Substances 0.000 claims description 8
- 238000000576 coating method Methods 0.000 claims description 8
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 7
- 239000000920 calcium hydroxide Substances 0.000 claims description 7
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 7
- 239000011248 coating agent Substances 0.000 claims description 7
- 239000008367 deionised water Substances 0.000 claims description 7
- 229910021641 deionized water Inorganic materials 0.000 claims description 7
- 239000012528 membrane Substances 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 230000000845 anti-microbial effect Effects 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims description 5
- 238000003556 assay Methods 0.000 claims description 5
- 239000003139 biocide Substances 0.000 claims description 5
- 238000011065 in-situ storage Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 239000001361 adipic acid Substances 0.000 claims description 4
- 235000011037 adipic acid Nutrition 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 claims description 4
- 239000003906 humectant Substances 0.000 claims description 4
- WLJVNTCWHIRURA-UHFFFAOYSA-N pimelic acid Chemical compound OC(=O)CCCCCC(O)=O WLJVNTCWHIRURA-UHFFFAOYSA-N 0.000 claims description 4
- TYFQFVWCELRYAO-UHFFFAOYSA-N suberic acid Chemical compound OC(=O)CCCCCCC(O)=O TYFQFVWCELRYAO-UHFFFAOYSA-N 0.000 claims description 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 3
- 239000012670 alkaline solution Substances 0.000 claims description 3
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 3
- 229910001919 chlorite Inorganic materials 0.000 claims description 3
- 229910052619 chlorite group Inorganic materials 0.000 claims description 3
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 claims description 3
- 235000006408 oxalic acid Nutrition 0.000 claims description 3
- 239000008363 phosphate buffer Substances 0.000 claims description 3
- 239000011973 solid acid Substances 0.000 claims description 3
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 claims description 2
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000012459 cleaning agent Substances 0.000 claims description 2
- 239000003086 colorant Substances 0.000 claims description 2
- 239000003974 emollient agent Substances 0.000 claims description 2
- 239000003623 enhancer Substances 0.000 claims description 2
- 239000003205 fragrance Substances 0.000 claims description 2
- DRGCYUIANHYKCC-UHFFFAOYSA-N [Na+].Cl[O-].OCl=O Chemical compound [Na+].Cl[O-].OCl=O DRGCYUIANHYKCC-UHFFFAOYSA-N 0.000 claims 1
- 125000000129 anionic group Chemical group 0.000 claims 1
- 239000003945 anionic surfactant Substances 0.000 claims 1
- 239000003093 cationic surfactant Substances 0.000 claims 1
- 235000015165 citric acid Nutrition 0.000 claims 1
- 229960001438 immunostimulant agent Drugs 0.000 claims 1
- 239000003022 immunostimulating agent Substances 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 239000004745 nonwoven fabric Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 14
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 18
- 238000009826 distribution Methods 0.000 description 16
- 239000004094 surface-active agent Substances 0.000 description 16
- 241000894007 species Species 0.000 description 15
- 238000011282 treatment Methods 0.000 description 14
- 241000894006 Bacteria Species 0.000 description 13
- 235000013305 food Nutrition 0.000 description 13
- 241000700605 Viruses Species 0.000 description 11
- 244000052769 pathogen Species 0.000 description 11
- 241000233866 Fungi Species 0.000 description 10
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical group Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 9
- 239000005708 Sodium hypochlorite Substances 0.000 description 9
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 9
- 230000001965 increasing effect Effects 0.000 description 8
- 208000015181 infectious disease Diseases 0.000 description 8
- 230000000813 microbial effect Effects 0.000 description 6
- 244000005700 microbiome Species 0.000 description 6
- 235000011121 sodium hydroxide Nutrition 0.000 description 6
- 235000013311 vegetables Nutrition 0.000 description 6
- 206010052428 Wound Diseases 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 5
- 239000000654 additive Substances 0.000 description 5
- 239000012267 brine Substances 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 229960004106 citric acid Drugs 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 238000005868 electrolysis reaction Methods 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 230000007794 irritation Effects 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- 238000011012 sanitization Methods 0.000 description 5
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 5
- 238000005507 spraying Methods 0.000 description 5
- 238000003860 storage Methods 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 4
- 108010010803 Gelatin Proteins 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 230000002378 acidificating effect Effects 0.000 description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 239000008273 gelatin Substances 0.000 description 4
- 229920000159 gelatin Polymers 0.000 description 4
- 235000019322 gelatine Nutrition 0.000 description 4
- 235000011852 gelatine desserts Nutrition 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 description 4
- 235000019645 odor Nutrition 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- YIROYDNZEPTFOL-UHFFFAOYSA-N 5,5-Dimethylhydantoin Chemical compound CC1(C)NC(=O)NC1=O YIROYDNZEPTFOL-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 239000003513 alkali Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 239000002585 base Substances 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 238000010411 cooking Methods 0.000 description 3
- 235000013365 dairy product Nutrition 0.000 description 3
- 238000006731 degradation reaction Methods 0.000 description 3
- 230000000249 desinfective effect Effects 0.000 description 3
- 239000006260 foam Substances 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 239000007800 oxidant agent Substances 0.000 description 3
- 230000001590 oxidative effect Effects 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- QZTKDVCDBIDYMD-UHFFFAOYSA-N 2,2'-[(2-amino-2-oxoethyl)imino]diacetic acid Chemical compound NC(=O)CN(CC(O)=O)CC(O)=O QZTKDVCDBIDYMD-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- XTEGARKTQYYJKE-UHFFFAOYSA-M Chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 description 2
- YASYEJJMZJALEJ-UHFFFAOYSA-N Citric acid monohydrate Chemical compound O.OC(=O)CC(O)(C(O)=O)CC(O)=O YASYEJJMZJALEJ-UHFFFAOYSA-N 0.000 description 2
- 241000193163 Clostridioides difficile Species 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 240000008415 Lactuca sativa Species 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- 208000003351 Melanosis Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 208000000260 Warts Diseases 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 235000015278 beef Nutrition 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 235000010233 benzoic acid Nutrition 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- HHKZCCWKTZRCCL-UHFFFAOYSA-N bis-tris propane Chemical compound OCC(CO)(CO)NCCCNC(CO)(CO)CO HHKZCCWKTZRCCL-UHFFFAOYSA-N 0.000 description 2
- 238000004061 bleaching Methods 0.000 description 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 2
- 239000001506 calcium phosphate Substances 0.000 description 2
- 229910000389 calcium phosphate Inorganic materials 0.000 description 2
- 235000011010 calcium phosphates Nutrition 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 2
- 230000006652 catabolic pathway Effects 0.000 description 2
- 238000005660 chlorination reaction Methods 0.000 description 2
- 229910001902 chlorine oxide Inorganic materials 0.000 description 2
- KVPIFZRDXDYGBA-UHFFFAOYSA-N chlorine(1+) Chemical compound [Cl+] KVPIFZRDXDYGBA-UHFFFAOYSA-N 0.000 description 2
- 229960002303 citric acid monohydrate Drugs 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000005238 degreasing Methods 0.000 description 2
- 230000001627 detrimental effect Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 235000019688 fish Nutrition 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000005187 foaming Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000006174 pH buffer Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 235000012045 salad Nutrition 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 239000003206 sterilizing agent Substances 0.000 description 2
- 239000011550 stock solution Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 239000008399 tap water Substances 0.000 description 2
- 235000020679 tap water Nutrition 0.000 description 2
- DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- YRIZYWQGELRKNT-UHFFFAOYSA-N 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione Chemical compound ClN1C(=O)N(Cl)C(=O)N(Cl)C1=O YRIZYWQGELRKNT-UHFFFAOYSA-N 0.000 description 1
- GSDQVZMTWWSMNU-UHFFFAOYSA-N 1-chloroimidazolidine-2,4-dione Chemical compound ClN1CC(=O)NC1=O GSDQVZMTWWSMNU-UHFFFAOYSA-N 0.000 description 1
- FKKAGFLIPSSCHT-UHFFFAOYSA-N 1-dodecoxydodecane;sulfuric acid Chemical class OS(O)(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC FKKAGFLIPSSCHT-UHFFFAOYSA-N 0.000 description 1
- IHPYMWDTONKSCO-UHFFFAOYSA-N 2,2'-piperazine-1,4-diylbisethanesulfonic acid Chemical compound OS(=O)(=O)CCN1CCN(CCS(O)(=O)=O)CC1 IHPYMWDTONKSCO-UHFFFAOYSA-N 0.000 description 1
- SXGZJKUKBWWHRA-UHFFFAOYSA-N 2-(N-morpholiniumyl)ethanesulfonate Chemical compound [O-]S(=O)(=O)CC[NH+]1CCOCC1 SXGZJKUKBWWHRA-UHFFFAOYSA-N 0.000 description 1
- ADIJLGOTHNVIMK-UHFFFAOYSA-N 2-[hydroxy(2-hydroxyethyl)amino]ethanol Chemical compound OCCN(O)CCO ADIJLGOTHNVIMK-UHFFFAOYSA-N 0.000 description 1
- BZSXEZOLBIJVQK-UHFFFAOYSA-N 2-methylsulfonylbenzoic acid Chemical compound CS(=O)(=O)C1=CC=CC=C1C(O)=O BZSXEZOLBIJVQK-UHFFFAOYSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- QNGVNLMMEQUVQK-UHFFFAOYSA-N 4-n,4-n-diethylbenzene-1,4-diamine Chemical compound CCN(CC)C1=CC=C(N)C=C1 QNGVNLMMEQUVQK-UHFFFAOYSA-N 0.000 description 1
- GGZZISOUXJHYOY-UHFFFAOYSA-N 8-amino-4-hydroxynaphthalene-2-sulfonic acid Chemical compound C1=C(S(O)(=O)=O)C=C2C(N)=CC=CC2=C1O GGZZISOUXJHYOY-UHFFFAOYSA-N 0.000 description 1
- 241000588625 Acinetobacter sp. Species 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 244000075850 Avena orientalis Species 0.000 description 1
- 239000007989 BIS-Tris Propane buffer Substances 0.000 description 1
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 239000004484 Briquette Substances 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 206010008570 Chloasma Diseases 0.000 description 1
- 239000004155 Chlorine dioxide Substances 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 206010056340 Diabetic ulcer Diseases 0.000 description 1
- 241000194029 Enterococcus hirae Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010014970 Ephelides Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 208000004898 Herpes Labialis Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 238000012696 Interfacial polycondensation Methods 0.000 description 1
- 102000004310 Ion Channels Human genes 0.000 description 1
- 241000588747 Klebsiella pneumoniae Species 0.000 description 1
- 235000019687 Lamb Nutrition 0.000 description 1
- 241000186779 Listeria monocytogenes Species 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 208000007117 Oral Ulcer Diseases 0.000 description 1
- 206010067152 Oral herpes Diseases 0.000 description 1
- 206010058667 Oral toxicity Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 208000004210 Pressure Ulcer Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010070835 Skin sensitisation Diseases 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 208000002847 Surgical Wound Diseases 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 208000000558 Varicose Ulcer Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001412 amines Chemical group 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000003429 antifungal agent Substances 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000000022 bacteriostatic agent Substances 0.000 description 1
- 238000003339 best practice Methods 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- SISAYUDTHCIGLM-UHFFFAOYSA-N bromine dioxide Inorganic materials O=Br=O SISAYUDTHCIGLM-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- YALMXYPQBUJUME-UHFFFAOYSA-L calcium chlorate Chemical compound [Ca+2].[O-]Cl(=O)=O.[O-]Cl(=O)=O YALMXYPQBUJUME-UHFFFAOYSA-L 0.000 description 1
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 description 1
- 239000001354 calcium citrate Substances 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 235000013330 chicken meat Nutrition 0.000 description 1
- XTEGARKTQYYJKE-UHFFFAOYSA-N chloric acid Chemical compound OCl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-N 0.000 description 1
- 229940005991 chloric acid Drugs 0.000 description 1
- 235000019398 chlorine dioxide Nutrition 0.000 description 1
- OGQPUOLFKIMRMF-UHFFFAOYSA-N chlorosulfamic acid Chemical compound OS(=O)(=O)NCl OGQPUOLFKIMRMF-UHFFFAOYSA-N 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000005354 coacervation Methods 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000002716 delivery method Methods 0.000 description 1
- 210000004262 dental pulp cavity Anatomy 0.000 description 1
- 239000002781 deodorant agent Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- CEJLBZWIKQJOAT-UHFFFAOYSA-N dichloroisocyanuric acid Chemical compound ClN1C(=O)NC(=O)N(Cl)C1=O CEJLBZWIKQJOAT-UHFFFAOYSA-N 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 description 1
- 239000002019 doping agent Substances 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 210000000883 ear external Anatomy 0.000 description 1
- 210000003027 ear inner Anatomy 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-N ethanesulfonic acid Chemical compound CCS(O)(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-N 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 230000005847 immunogenicity Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000012994 industrial processing Methods 0.000 description 1
- 239000010804 inert waste Substances 0.000 description 1
- 230000015788 innate immune response Effects 0.000 description 1
- 229910001502 inorganic halide Inorganic materials 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 229940048866 lauramine oxide Drugs 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 210000000088 lip Anatomy 0.000 description 1
- LWXVCCOAQYNXNX-UHFFFAOYSA-N lithium hypochlorite Chemical compound [Li+].Cl[O-] LWXVCCOAQYNXNX-UHFFFAOYSA-N 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229910052751 metal Chemical group 0.000 description 1
- 239000002184 metal Chemical group 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 229960003085 meticillin Drugs 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000002663 nebulization Methods 0.000 description 1
- 230000002352 nonmutagenic effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 231100000418 oral toxicity Toxicity 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 229940086539 peg-7 glyceryl cocoate Drugs 0.000 description 1
- 230000003239 periodontal effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000003761 preservation solution Substances 0.000 description 1
- 230000004845 protein aggregation Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 108700004121 sarkosyl Proteins 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 238000010956 selective crystallization Methods 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 231100000370 skin sensitisation Toxicity 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229940057950 sodium laureth sulfate Drugs 0.000 description 1
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 1
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 230000003330 sporicidal effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- 229950009390 symclosene Drugs 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- ISIJQEHRDSCQIU-UHFFFAOYSA-N tert-butyl 2,7-diazaspiro[4.5]decane-7-carboxylate Chemical compound C1N(C(=O)OC(C)(C)C)CCCC11CNCC1 ISIJQEHRDSCQIU-UHFFFAOYSA-N 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 210000002105 tongue Anatomy 0.000 description 1
- 210000000515 tooth Anatomy 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- 150000003628 tricarboxylic acids Chemical class 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B11/00—Oxides or oxyacids of halogens; Salts thereof
- C01B11/04—Hypochlorous acid
- C01B11/06—Hypochlorites
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B11/00—Oxides or oxyacids of halogens; Salts thereof
- C01B11/04—Hypochlorous acid
- C01B11/06—Hypochlorites
- C01B11/064—Hypochlorites of alkaline-earth metals
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B11/00—Oxides or oxyacids of halogens; Salts thereof
- C01B11/04—Hypochlorous acid
- C01B11/06—Hypochlorites
- C01B11/068—Stabilisation by additives other than oxides, hydroxides, carbonates of alkali or alkaline-earth metals; Coating of particles; Shaping; Granulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Geology (AREA)
- General Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
シェルまたは外膜内にカプセル化される。ヒカゲノカズラなどの種に由来する植物花粉または胞子は、化学的または酵素処理によって除去される内部遺伝物質を有し、外膜と称される、多孔性で不活性の弾性シェルを残す。活性成分は、胞子に移行され、その後放出まで保護される。水と共に混合されるとき、胞子は、所定のpHおよびppmでHOClを生成するために、酸と次亜塩素酸塩とを混合できるようにそれらの内容物を放出する。シェルは、特に有益である。なぜなら、それらは、アルカリおよび酸処理だけではなく、少なくとも250℃の温度に耐えることができるからである。シェル内の比較的大きな中央の空隙は、40ミクロンの直径の粒子について4:1(活性成分:外膜、重量:重量)などの高い搭載量を得ることができることを意味する。
・免疫原性および刺激を高めることなどの、がん細胞の酸化による治療。
・日焼け、日光で損傷した皮膚、そばかす、肝斑、いぼ、いぼ状突起、およびにきびの治療。
・老化した皮膚、および損傷した皮膚の治療。
・瘢痕および瘢痕組織の治療。
・乾癬および湿疹、口唇ヘルペス、足白癬、斑点および皮膚潰瘍、口腔内潰瘍、歯肉炎、ならびに一般的な歯周衛生の治療。
・一般な殺真菌薬および農薬としての使用。
・噴霧によって浮遊する病原体の、低減および除去、ならびに人間および動物の、結核などの肺疾患の治療。
実施例1:本発明に係る低い塩化物レベルを有する安定なHOCl組成物の検討。
本発明は、次亜塩素酸の真の安定化に関する。多くの人々が、異なる化合物または複合体を形成するために、次亜塩素酸塩または次亜塩素酸に結合する添加剤の使用を提案した。これらの材料は、溶液を安定化させると言われている。したがって、溶液は純粋な次亜塩素酸ではないが、次亜塩素酸と添加剤との平衡状態にある。
1)最大の次亜塩素酸濃度は、〜pH5.5で得られる。
2)pH5.5において、低いが有意なレベルの次亜塩素酸イオンが存在する。
3)pH5.5において、低いが有意なレベルのCl2(水溶液)が存在する。
4)pH5.5以下において、Cl2(水溶液)レベルが増加する。塩素は、排気される。
1)次亜塩素酸塩の曲線は、ほとんど変化しない。
2)最大の次亜塩素酸濃度は、pH6.0に移行した。
3)次亜塩素酸の最大レベルは、低下した。
4)塩素分布曲線は、2分の1のpH単位でpH5.5に移行した。
このプロットは、高塩化物溶液(たとえば、電気化学的に生成される次亜塩素酸)における次亜塩素酸レベルは制限されており、塩素がより容易に生成されることを示している。
1)次亜塩素酸塩の分布曲線は、ほとんど変化しない。
2)100%の次亜塩素酸は、pHのより広い範囲にわたって可能である。
3)塩素分布曲線は、塩化物濃度が一桁減少すると1pH単位低いpHに移行する。
これらのプロットは、安定した次亜塩素酸が低塩化物溶液中でより容易に生成することができることを示している。プロットは、低塩化物溶液中の低pHでも少ない塩素が存在することを示しているので、塩素の排気が大幅に低減される。塩素の排気は、次亜塩素酸溶液の分解の主な経路であり、pHを酸性方向に調整する方法を制限している。本発明は、この経路の分解を制限することができることを示している。
1)塩化物および塩素酸塩へ
2)酸素および塩化物へ
溶液のpHがより低いpHに移行すると、次亜塩素酸に有利な次亜塩素酸塩濃度が減少する。上述のように、次亜塩素酸は安定化することができる。次亜塩素酸塩濃度が非常に低いので、これら2つの次亜塩素酸分解経路による損失が低減される。
包装され、正しく保存された場合、製品は6カ月以上高い遊離塩素レベルを維持する。
Claims (26)
- 次亜塩素酸の安定な溶液を含む組成物であって、
塩化物と次亜塩素酸との割合は、塩化物:次亜塩素酸が最大で1:3であり、前記溶液のpHが、3.5〜7.0の間のpHで維持され、そのことによって、前記安定なHOClが、その抗菌活性を少なくとも1か月にわたって保持することを特徴とする組成物。 - pHは、5.5〜6.5の間に維持されることを特徴とする請求項1に記載の組成物。
- 塩化物と次亜塩素酸との割合は、1:8の塩化物と次亜塩素酸との塩化物レベルを有することを特徴とする請求項1または2に記載の組成物。
- ハロゲン安定性のアニオンまたはカチオン性界面活性剤、保湿剤、香料、皮膚軟化剤、キレート剤、着色剤、光エンハンサ、殺生物剤または免疫賦活剤、亜塩素酸塩ドナー、ハロゲン放出剤、および平衡安定化剤からなる群から選択される1以上の追加の成分をさらに含むことを特徴とする請求項1〜3のいずれか1項に記載の組成物。
- 低塩化次亜塩素酸ナトリウムを製造するための、請求項1〜4のいずれか1項に記載の組成物の使用。
- 次亜塩素酸の安定な水溶液を作製するための方法であって、
塩化物の源を水に添加する工程と、
得られる溶液の塩化物レベルを、塩化物:次亜塩素酸が最大で1:3になるように操作する工程と、
前記溶液のpHを3.5〜7.0の間に制御する工程とを含むことを特徴とする方法。 - 塩素源が次亜塩素酸カルシウムであり、水が脱イオン水であり、リン酸が前記溶液のpHを維持することを特徴とする請求項6に記載の方法。
- 組成物は、使用の時点においてその場で生成されることを特徴とする請求項6または7に記載の方法。
- 固体の次亜塩素酸塩と、リン酸塩緩衝液とを水に添加することによって作製されることを特徴とする請求項1に記載の水溶液。
- 低い塩化物レベルを有する次亜塩素酸水溶液を作製するための方法であって、
固体の次亜塩素酸塩と、少なくとも1つのリン酸緩衝液とを脱イオン水に添加する工程を含むことを特徴とする方法。 - 極低次亜塩素酸カルシウムが使用されることを特徴とする請求項6〜8および10のいずれか1項に記載の方法。
- 少なくとも70%のアッセイピュア(assay pure)な次亜塩素酸カルシウムが使用されることを特徴とする請求項11に記載の方法。
- 塩素を水酸化カルシウムに添加し、次亜塩素酸カルシウムと塩化カルシウムと水との溶液を得る工程と、
溶液中の塩化カルシウムを除去し、固体の次亜塩素酸カルシウムを得る工程と、
次亜塩素酸カルシウムを水に溶解させ、カルシウムおよび次亜塩素酸イオンのアルカリ溶液を得る工程と、
カルシウムを水酸化カルシウムとして沈殿させ、それを後に除去することを可能にする工程と、
得られる溶液の次亜塩素酸イオンのpHを約5〜6に調整し、残りのカルシウムを沈殿させ、それを後に除去することを可能にする工程と、
次亜塩素酸溶液のpHを、3.5〜7の間のpHに調整する工程とをさらに含むことを特徴とする請求項6に記載の方法。 - 請求項6〜8および10〜13のいずれか1項に記載の方法によって作製されることを特徴とする次亜塩素酸の安定な水溶液。
- 次亜塩素酸の安定な溶液の作製における使用のための固体組成物であって、
固体ハロゲン源、および分離された固体酸を含み、
前記ハロゲン源および酸は、非ハロゲン要求性被覆によって、共に、または独立してカプセル化されることを特徴とする固体組成物。 - ハロゲン源は、極低塩化次亜塩素酸カルシウムを含むことを特徴とする請求項15に記載の組成物。
- 前記酸は、クエン酸、アジピン酸、シュウ酸、マロン酸、コハク酸、グルタル酸、ピメリン酸、スベリン酸およびリン酸からなる群から選択されることを特徴とする請求項15または16に記載の組成物。
- 前記酸は、クエン酸であることを特徴とする請求項17に記載の組成物。
- 前記ハロゲン源および酸は、別々にカプセル化されることを特徴とする請求項15〜18のいずれか1項に記載の組成物。
- 前記ハロゲン源および酸は、共にカプセル化されることを特徴とする請求項15〜18のいずれか1項に記載の組成物。
- 前記被覆は、水溶性であることを特徴とする請求項15〜20のいずれか1項に記載の組成物。
- 前記ハロゲン源および酸は、胞子または花粉から得られる外膜内に封入されることを特徴とする請求項15〜20のいずれか1項に記載の組成物。
- 請求項1〜4、9および14のいずれか1項に記載される、または請求項15〜22の組成物から製造される、次亜塩素酸の安定な水溶液の、抗菌剤としての使用。
- 請求項1〜4、9および14のいずれか1項に記載される、または請求項15〜22の組成物から製造される、次亜塩素酸の安定な水溶液の、洗浄剤または殺菌剤としての使用。
- 請求項1〜4、9および14、ならびに請求項15〜22のいずれか1項に記載の組成物を含浸することを特徴とする不織布材料。
- 請求項1〜4、9および14、ならびに請求項15〜22のいずれか1項に記載の組成物に対象物を接触させることを含むことを特徴とする、生物または無生物の殺菌方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1104180.3 | 2011-03-11 | ||
GB1104180.3A GB2488838A (en) | 2011-03-11 | 2011-03-11 | A stable antimicrobial aqueous hypochlorous acid solution |
PCT/GB2012/000228 WO2012123695A2 (en) | 2011-03-11 | 2012-03-08 | A stable composition of hoci, processes for its production and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014515737A true JP2014515737A (ja) | 2014-07-03 |
JP2014515737A5 JP2014515737A5 (ja) | 2015-04-23 |
Family
ID=43980865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013558492A Pending JP2014515737A (ja) | 2011-03-11 | 2012-03-08 | HOClの安定な組成物、その製造方法、およびその使用 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20140134224A1 (ja) |
EP (1) | EP2683240A2 (ja) |
JP (1) | JP2014515737A (ja) |
CN (1) | CN103501605B (ja) |
BR (1) | BR112013023170A2 (ja) |
CA (1) | CA2829449A1 (ja) |
CL (1) | CL2013002599A1 (ja) |
EA (1) | EA201391317A1 (ja) |
GB (1) | GB2488838A (ja) |
MX (1) | MX2013010362A (ja) |
WO (1) | WO2012123695A2 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014518844A (ja) * | 2011-03-18 | 2014-08-07 | プリコア,インコーポレイテッド | 安定化次亜ハロゲン酸溶液 |
JP2017222535A (ja) * | 2016-06-14 | 2017-12-21 | 淳一 熊倉 | 次亜塩素酸水溶液の製造又は調製方法及び装置 |
KR20220154289A (ko) | 2021-05-12 | 2022-11-22 | 이희두 | 드라이포그 방식의 공기(Air) 살균소독세척 방역 시스템 |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2656825T3 (es) | 2010-04-14 | 2018-02-28 | Hypo-Stream Limited | Dispositivo para preparar una solución desinfectante diluida |
US11484549B2 (en) | 2012-02-17 | 2022-11-01 | Wiab Water Innovation Ab | Compositions and methods for treating biofilms without inducing antimicrobial resistance |
US11364262B2 (en) | 2012-02-17 | 2022-06-21 | Wiab Water Innovation Ab | Acetic acid and hypochlorous acid compositions for treatment of skin trauma |
US11364263B2 (en) | 2012-02-17 | 2022-06-21 | Wiab Wafer Innovation Ab | Compositions and methods for aerodigestive treatment |
WO2013121294A1 (en) | 2012-02-17 | 2013-08-22 | Wiab Water Innovation Ab | Compositions of hypochlorous acid (hoci) and methods of manufacture thereof |
US11452741B2 (en) | 2012-02-17 | 2022-09-27 | Wiab Water Innovation Ab | Compositions and methods for treating transient biofilms |
US11672825B2 (en) * | 2012-02-17 | 2023-06-13 | Wiab Water Innovation Ab | Acetic acid and hypochlorous acid compositions for treatment of biofilms and wound care |
US11478507B2 (en) * | 2012-02-17 | 2022-10-25 | Wiab Water Innovation Ab | Compositions and methods for treating biofilms |
US9918477B2 (en) | 2013-05-22 | 2018-03-20 | Sonoma Pharmaceuticals, Inc. | Stabilized hypochlorous acid solution and use thereof |
WO2015061632A2 (en) * | 2013-10-23 | 2015-04-30 | O'connell John F | Antimicrobial compositions and articles |
GB2521810A (en) * | 2013-10-25 | 2015-07-08 | Global Chemical Technologies Ltd | Method and apparatus for making stable acidic chlorinated solutions |
EP3062799A1 (en) * | 2013-10-29 | 2016-09-07 | Hypo-Stream Limited | Anti-inflammatory solution comprising sodium hypochlorite |
US9578879B1 (en) | 2014-02-07 | 2017-02-28 | Gojo Industries, Inc. | Compositions and methods having improved efficacy against spores and other organisms |
EP3736319A1 (en) | 2014-02-07 | 2020-11-11 | GOJO Industries, Inc. | Compositions and methods with efficacy against spores and other organisms |
GB2532070B (en) | 2014-11-07 | 2018-05-09 | Xanadox Tech Limited | Improvements relating to hypochlorous acid solutions |
US10897905B2 (en) * | 2016-01-26 | 2021-01-26 | Metrex Research, LLC | Hypochlorite based hard surface disinfectants |
WO2017189792A1 (en) * | 2016-04-27 | 2017-11-02 | Biiosmart Technologies Llc | Use of hypochlorous acid as a topical antimicrobial |
EP3466870A4 (en) * | 2016-05-30 | 2020-02-12 | Nippon Light Metal Company, Ltd. | SURFACE MODIFIED SODIUM PENTAHYDRATE SODIUM HYPOCHLORHITE CRYSTAL AND METHOD FOR PRODUCING THE SAME |
CN106386850A (zh) * | 2016-11-23 | 2017-02-15 | 沐康源科技(北京)有限公司 | 一种微酸性次氯酸水制备方法及装置 |
JP7274423B2 (ja) | 2017-01-13 | 2023-05-16 | ファーモコン エルエルシー | 活性塩素溶液を緩衝するための材料及び方法 |
WO2020049955A1 (ja) * | 2018-09-06 | 2020-03-12 | 富士フイルム株式会社 | 薬液、基板の処理方法 |
RU2711189C1 (ru) * | 2018-10-12 | 2020-01-15 | Федеральное государственное бюджетное научное учреждение "Федеральный научный центр - Всероссийский научно-исследовательский институт экспериментальной ветеринарии имени К.И. Скрябина и Я.Р. Коваленко Российской академии наук" (ФГБНУ ФНЦ ВИЭВ РАН) | Способ дезинфекции объектов ветеринарного надзора |
RU2710600C1 (ru) * | 2018-10-12 | 2019-12-30 | Федеральное государственное бюджетное научное учреждение "Федеральный научный центр - Всероссийский научно-исследовательский институт экспериментальной ветеринарии имени К.И. Скрябина и Я.Р. Коваленко Российской академии наук" (ФГБНУ ФНЦ ВИЭВ РАН) | Способ дезинфекции объектов ветеринарного надзора |
US10986841B2 (en) | 2018-11-06 | 2021-04-27 | The Clorox Company | Bleach compositions |
SG11202105842XA (en) * | 2018-12-27 | 2021-07-29 | Arlanxeo Singapore Pte Ltd | Process for producing chlorinated butyl rubber |
GB201902731D0 (en) | 2019-02-28 | 2019-04-17 | Clinical Health Tech Ltd | Stabilised hypochlorous solutions and their medical use |
CN110074133A (zh) * | 2019-05-08 | 2019-08-02 | 上海滤郎科技发展有限公司 | 一种微酸性次氯酸溶液的制备方法 |
CN110123834A (zh) * | 2019-05-08 | 2019-08-16 | 山东消博士消毒科技股份有限公司 | 一种次氯酸消毒液及其制备方法 |
JP2022536927A (ja) | 2019-06-14 | 2022-08-22 | コリディオン,インコーポレイテッド | 微生物増殖を防止するための組成物、キット、方法、および使用 |
WO2021002262A1 (ja) * | 2019-07-02 | 2021-01-07 | 大幸薬品株式会社 | 二酸化塩素発生装置および二酸化塩素発生方法 |
US20230149444A1 (en) * | 2020-04-03 | 2023-05-18 | Phase One Health, Llc | Hypochlorous acid solutions and methods of use |
EP4155261A4 (en) * | 2020-05-22 | 2023-11-29 | Nipro Corporation | SEPARATION APPARATUS AND SYSTEM FOR REMOVING IMPURITIES IONS FROM AN AQUEOUS HYPOCHLOROUS ACID SOLUTION |
US11845916B2 (en) | 2020-06-24 | 2023-12-19 | The Clorox Company | Burstable sporicidal cleaning wipe system containing stabilized hypochlorite |
CN112374464A (zh) * | 2020-08-10 | 2021-02-19 | 中山市原域企业投资有限公司 | 一种离子交换法结合电解法制备次氯酸的方法及设备 |
CN112499591A (zh) * | 2020-08-10 | 2021-03-16 | 中山市原域企业投资有限公司 | 一种两液合成结合微孔分子筛制备次氯酸的方法及设备 |
CN112501638A (zh) * | 2020-08-10 | 2021-03-16 | 中山市原域企业投资有限公司 | 一种两液法结合电解法制备次氯酸的工艺及设备 |
CN112499800A (zh) * | 2020-08-10 | 2021-03-16 | 中山市原域企业投资有限公司 | 一种两液合成结合离子交换法制备次氯酸的方法及设备 |
CN112586506A (zh) * | 2020-12-26 | 2021-04-02 | 深圳市疆河生物科技有限公司 | 一种高稳定的分子态次氯酸水溶液及其制备方法 |
WO2022243919A1 (en) * | 2021-05-20 | 2022-11-24 | Swiss Newater Holding Sàrl | A sanitizer composition comprising electrolyzed water |
EP4332272A1 (en) | 2022-08-31 | 2024-03-06 | Ioannis Kontonis | Solution |
CN115868482A (zh) * | 2022-11-30 | 2023-03-31 | 上海卓景生物科技有限公司 | 一种次氯酸钠消毒液的生产工艺 |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11228316A (ja) * | 1998-02-19 | 1999-08-24 | Clean Chemical Kk | 殺菌消毒用製剤 |
US6162371A (en) * | 1997-12-22 | 2000-12-19 | S. C. Johnson & Son, Inc. | Stabilized acidic chlorine bleach composition and method of use |
JP2001342496A (ja) * | 2000-03-31 | 2001-12-14 | Kao Corp | 硬質表面用殺菌洗浄剤組成物 |
JP2002249407A (ja) * | 2001-02-22 | 2002-09-06 | Tsukasa Denshi Kk | 殺菌消毒剤 |
JP2002537405A (ja) * | 1999-02-24 | 2002-11-05 | ケイ ケミカル カンパニー | 色彩の安定した次亜塩素酸消毒剤および方法 |
US20040226894A1 (en) * | 2003-05-12 | 2004-11-18 | Tatsuo Okazaki | Method of preparing a sterile water containing hypochlorous or chlorous acid, package of sterile source materials, and sterile water preparation kit |
JP2004337582A (ja) * | 2003-10-27 | 2004-12-02 | Tatsuo Okazaki | 殺菌液保存方法及び殺菌用容器並びにこれに用いられる開閉弁付きノズル |
JP2005000238A (ja) * | 2003-06-09 | 2005-01-06 | Hiromaito Co Ltd | 殺菌剤水溶液充填容器の製造方法 |
JP2007520430A (ja) * | 2003-06-27 | 2007-07-26 | ユニバーシティ オブ ハル | 製剤 |
US20090258083A1 (en) * | 2008-04-11 | 2009-10-15 | Justo Leonardo Calderon | Method of producing and applications of composition of hypochlorous acid |
WO2010148004A1 (en) * | 2009-06-15 | 2010-12-23 | Oculus Innovative Sciences, Inc. | Solution containing hypochlorous acid and methods of using same |
US20120301556A1 (en) * | 2010-02-03 | 2012-11-29 | Mauve Technology Ltd. | Disinfectant Materials and Methods |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2111194A (en) * | 1934-01-12 | 1938-03-15 | Sanchez Pedro | Method of producing hypochlorous acid solution |
US2438781A (en) | 1944-09-07 | 1948-03-30 | Boyle Midway Inc | Stabilized hypochlorite solutions and process therefor |
GB1021287A (en) | 1964-09-21 | 1966-03-02 | Samuel Raymond | Improvements in vertical gel electrophoresis apparatus |
US3791840A (en) * | 1970-10-21 | 1974-02-12 | Union Carbide Corp | Treatment of carbon fibers to improve shear strength in composites |
US3749672A (en) | 1971-04-19 | 1973-07-31 | Du Pont | Stabilized solutions of n-halo compounds |
AU536179B2 (en) * | 1979-05-29 | 1984-04-19 | Toyo Soda Manufacturing Co. Ltd. | Calcium hypochlorite |
GB2078522B (en) * | 1980-06-26 | 1984-01-11 | Antec Ah International Ltd | Improvements in and relating to sanitizing compositions |
US4337236A (en) | 1980-08-07 | 1982-06-29 | Olin Corporation | Process for manufacture of calcium hypochlorite |
US4468377A (en) * | 1983-03-07 | 1984-08-28 | Olin Corporation | Continuous process for the manufacture of calcium hypochlorite |
GB8920973D0 (en) | 1989-09-15 | 1989-11-01 | Auchincloss Thomas R | Effervescent tablets |
CA2028930A1 (en) * | 1990-10-30 | 1992-05-01 | Norman A. Miner | Stable hypochlorous acid sterilizing solution and kit |
US5532389A (en) * | 1993-11-23 | 1996-07-02 | The Dow Chemical Company | Process for preparing alkylene oxides |
US6019905A (en) * | 1998-01-20 | 2000-02-01 | Waggoner; Mark B. | Process for sanitizing chlorinated water |
US6471974B1 (en) | 1999-06-29 | 2002-10-29 | S.C. Johnson & Son, Inc. | N-chlorosulfamate compositions having enhanced antimicrobial efficacy |
WO2001041571A1 (fr) * | 1999-12-10 | 2001-06-14 | Kao Corporation | Compositions microbicides |
JP2003040715A (ja) * | 2001-07-26 | 2003-02-13 | Tadashi Inoue | 次亜塩素酸水溶液散布による農作物病害の防除方法 |
US20040256330A1 (en) * | 2003-05-12 | 2004-12-23 | Tatsuo Okazaki | Method of preparing sterile water containing hypochlorous or chlorous acid, package of sterile source materials, sterile water preparation kit, method and apparatus for spatial sterilization |
JPWO2004098657A1 (ja) * | 2003-05-12 | 2006-07-13 | 岡崎 龍夫 | 次亜塩素酸又は亜塩素酸を含む殺菌水の生成方法、殺菌原料パッケージ及び殺菌水生成キット並びに空間殺菌方法及び装置 |
-
2011
- 2011-03-11 GB GB1104180.3A patent/GB2488838A/en not_active Withdrawn
-
2012
- 2012-03-08 CA CA2829449A patent/CA2829449A1/en not_active Abandoned
- 2012-03-08 EP EP12712138.2A patent/EP2683240A2/en not_active Withdrawn
- 2012-03-08 CN CN201280012861.0A patent/CN103501605B/zh not_active Expired - Fee Related
- 2012-03-08 MX MX2013010362A patent/MX2013010362A/es not_active Application Discontinuation
- 2012-03-08 BR BR112013023170A patent/BR112013023170A2/pt not_active IP Right Cessation
- 2012-03-08 EA EA201391317A patent/EA201391317A1/ru unknown
- 2012-03-08 WO PCT/GB2012/000228 patent/WO2012123695A2/en active Application Filing
- 2012-03-08 US US14/004,094 patent/US20140134224A1/en not_active Abandoned
- 2012-03-08 JP JP2013558492A patent/JP2014515737A/ja active Pending
-
2013
- 2013-09-10 CL CL2013002599A patent/CL2013002599A1/es unknown
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6162371A (en) * | 1997-12-22 | 2000-12-19 | S. C. Johnson & Son, Inc. | Stabilized acidic chlorine bleach composition and method of use |
JPH11228316A (ja) * | 1998-02-19 | 1999-08-24 | Clean Chemical Kk | 殺菌消毒用製剤 |
JP2002537405A (ja) * | 1999-02-24 | 2002-11-05 | ケイ ケミカル カンパニー | 色彩の安定した次亜塩素酸消毒剤および方法 |
JP2001342496A (ja) * | 2000-03-31 | 2001-12-14 | Kao Corp | 硬質表面用殺菌洗浄剤組成物 |
JP2002249407A (ja) * | 2001-02-22 | 2002-09-06 | Tsukasa Denshi Kk | 殺菌消毒剤 |
US20040226894A1 (en) * | 2003-05-12 | 2004-11-18 | Tatsuo Okazaki | Method of preparing a sterile water containing hypochlorous or chlorous acid, package of sterile source materials, and sterile water preparation kit |
JP2005000238A (ja) * | 2003-06-09 | 2005-01-06 | Hiromaito Co Ltd | 殺菌剤水溶液充填容器の製造方法 |
JP2007520430A (ja) * | 2003-06-27 | 2007-07-26 | ユニバーシティ オブ ハル | 製剤 |
JP2004337582A (ja) * | 2003-10-27 | 2004-12-02 | Tatsuo Okazaki | 殺菌液保存方法及び殺菌用容器並びにこれに用いられる開閉弁付きノズル |
US20090258083A1 (en) * | 2008-04-11 | 2009-10-15 | Justo Leonardo Calderon | Method of producing and applications of composition of hypochlorous acid |
WO2010148004A1 (en) * | 2009-06-15 | 2010-12-23 | Oculus Innovative Sciences, Inc. | Solution containing hypochlorous acid and methods of using same |
US20120301556A1 (en) * | 2010-02-03 | 2012-11-29 | Mauve Technology Ltd. | Disinfectant Materials and Methods |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014518844A (ja) * | 2011-03-18 | 2014-08-07 | プリコア,インコーポレイテッド | 安定化次亜ハロゲン酸溶液 |
JP2017222535A (ja) * | 2016-06-14 | 2017-12-21 | 淳一 熊倉 | 次亜塩素酸水溶液の製造又は調製方法及び装置 |
KR20220154289A (ko) | 2021-05-12 | 2022-11-22 | 이희두 | 드라이포그 방식의 공기(Air) 살균소독세척 방역 시스템 |
Also Published As
Publication number | Publication date |
---|---|
MX2013010362A (es) | 2014-04-14 |
US20140134224A1 (en) | 2014-05-15 |
CA2829449A1 (en) | 2012-09-20 |
GB201104180D0 (en) | 2011-04-27 |
WO2012123695A2 (en) | 2012-09-20 |
EP2683240A2 (en) | 2014-01-15 |
CN103501605B (zh) | 2015-07-22 |
EA201391317A1 (ru) | 2014-02-28 |
BR112013023170A2 (pt) | 2016-07-26 |
GB2488838A (en) | 2012-09-12 |
WO2012123695A3 (en) | 2013-08-01 |
CN103501605A (zh) | 2014-01-08 |
CL2013002599A1 (es) | 2014-10-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2014515737A (ja) | HOClの安定な組成物、その製造方法、およびその使用 | |
US10576152B2 (en) | Stabilized hypohalous acid solutions | |
US7087190B2 (en) | Composition for the production of chlorine dioxide using non-iodo interhalides or polyhalides and methods of making and using the same | |
JP6723243B2 (ja) | 電解水組成物 | |
US20140328945A1 (en) | METHOD FOR STABILIZING AN ELECTROCHEMICALLY GENERATED SANITIZING SOLUTION HAVING A PREDETERMINED LEVEL OF FREE AVAILABLE CHLORINE AND pH | |
JP2012072134A (ja) | 抗菌用銀イオン生成液、その液から生成された銀イオン抗菌液及びその抗菌液を生成する生成方法 | |
BRPI0617067A2 (pt) | composição com acidez controlada | |
US11452778B2 (en) | Stabilized hypohalous acid solutions | |
US20220355283A1 (en) | Drug, drug manufacturing method, and water purification method | |
GB2486454A (en) | A stable composition of hypochlorous acid (HOCl), its production and uses thereof | |
JPS6143322B2 (ja) | ||
KR102371834B1 (ko) | 이산화염소 수용액을 이용한 악취제거제의 제조방법과 이산화염소 수용액이 혼합된 악취제거제 | |
Yan et al. | New Clinical Applications of Electrolyzed Water: A Review. Microorganisms 2021, 9, 136 | |
RU2736364C2 (ru) | Дезинфицирующая композиция с винной кислотой, молочной кислотой | |
EP4358977A1 (en) | Stabilised hypohalous acid solutions | |
Zahra | Basic Principle of Disinfectant |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150306 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150306 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20151022 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160105 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20160405 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20160802 |