JP2014510067A5 - - Google Patents
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- Publication number
- JP2014510067A5 JP2014510067A5 JP2013555797A JP2013555797A JP2014510067A5 JP 2014510067 A5 JP2014510067 A5 JP 2014510067A5 JP 2013555797 A JP2013555797 A JP 2013555797A JP 2013555797 A JP2013555797 A JP 2013555797A JP 2014510067 A5 JP2014510067 A5 JP 2014510067A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- administration
- pain
- dosage form
- tapentadol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims description 12
- KWTWDQCKEHXFFR-SMDDNHRTSA-N tapentadol Chemical compound CN(C)C[C@H](C)[C@@H](CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-SMDDNHRTSA-N 0.000 claims description 8
- 229960005126 tapentadol Drugs 0.000 claims description 8
- 239000003755 preservative agent Substances 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims 4
- 208000002193 Pain Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 206010058019 Cancer Pain Diseases 0.000 claims 1
- 208000004550 Postoperative Pain Diseases 0.000 claims 1
- 230000003444 anaesthetic effect Effects 0.000 claims 1
- 239000003405 delayed action preparation Substances 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000007914 intraventricular administration Methods 0.000 claims 1
- 208000004296 neuralgia Diseases 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161449317P | 2011-03-04 | 2011-03-04 | |
| US61/449,317 | 2011-03-04 | ||
| EP11003602 | 2011-05-03 | ||
| EP11003602.7 | 2011-05-03 | ||
| PCT/EP2012/000905 WO2012119728A1 (en) | 2011-03-04 | 2012-03-02 | Parenteral administration of tapentadol |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017158324A Division JP6837944B2 (ja) | 2011-03-04 | 2017-08-21 | タペンタドールの非経口的投与 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014510067A JP2014510067A (ja) | 2014-04-24 |
| JP2014510067A5 true JP2014510067A5 (enExample) | 2016-08-25 |
Family
ID=44653043
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013555797A Pending JP2014510067A (ja) | 2011-03-04 | 2012-03-02 | タペンタドールの非経口的投与 |
| JP2017158324A Expired - Fee Related JP6837944B2 (ja) | 2011-03-04 | 2017-08-21 | タペンタドールの非経口的投与 |
| JP2021195330A Pending JP2022033863A (ja) | 2011-03-04 | 2021-12-01 | タペンタドールの非経口的投与 |
| JP2023037505A Pending JP2023075244A (ja) | 2011-03-04 | 2023-03-10 | タペンタドールの非経口的投与 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017158324A Expired - Fee Related JP6837944B2 (ja) | 2011-03-04 | 2017-08-21 | タペンタドールの非経口的投与 |
| JP2021195330A Pending JP2022033863A (ja) | 2011-03-04 | 2021-12-01 | タペンタドールの非経口的投与 |
| JP2023037505A Pending JP2023075244A (ja) | 2011-03-04 | 2023-03-10 | タペンタドールの非経口的投与 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US20120225951A1 (enExample) |
| EP (2) | EP3025710A1 (enExample) |
| JP (4) | JP2014510067A (enExample) |
| KR (2) | KR101970468B1 (enExample) |
| CN (2) | CN103501775A (enExample) |
| AU (2) | AU2012224953C1 (enExample) |
| BR (1) | BR112013022213A2 (enExample) |
| CA (1) | CA2828635C (enExample) |
| CY (1) | CY1117426T1 (enExample) |
| DK (1) | DK2680833T3 (enExample) |
| EA (2) | EA028149B1 (enExample) |
| ES (1) | ES2573414T3 (enExample) |
| HR (1) | HRP20160400T1 (enExample) |
| HU (1) | HUE027514T2 (enExample) |
| IL (1) | IL227825A (enExample) |
| MX (1) | MX348831B (enExample) |
| PL (1) | PL2680833T3 (enExample) |
| PT (1) | PT2680833E (enExample) |
| RS (1) | RS54711B1 (enExample) |
| SI (1) | SI2680833T1 (enExample) |
| WO (1) | WO2012119728A1 (enExample) |
| ZA (1) | ZA201306479B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011267474B2 (en) | 2010-06-15 | 2016-05-26 | Grünenthal GmbH | Pharmaceutical combination for the treatment of pain |
| LT2680832T (lt) | 2011-03-04 | 2019-10-25 | Gruenenthal Gmbh | Tapentadolio vandeninė farmacinė kompozicija, skirta vartoti geriant |
| PT2736501T (pt) | 2011-07-29 | 2018-03-26 | Gruenenthal Gmbh | Administração intratecal ou epidural de 3-[(1s,2s)-3-(dimetilamino)-1-etil-2-metilpropil]fenol |
| US9629818B2 (en) | 2012-11-01 | 2017-04-25 | Torrent Pharmaceuticals Ltd. | Pharmaceutical composition of tapentadol for parenteral administration |
| EP2808319A1 (en) | 2013-05-31 | 2014-12-03 | Arevipharma GmbH | 3-[3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol resin complex |
| EP2845625A1 (en) | 2013-09-04 | 2015-03-11 | Grünenthal GmbH | Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome |
| CN103735500B (zh) * | 2014-01-28 | 2016-01-20 | 江苏华泽医药科技有限公司 | 盐酸他喷他多注射液及其制备方法 |
| JP6923447B2 (ja) * | 2015-03-27 | 2021-08-18 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | タペンタドールの非経口投与のための安定な製剤 |
| EP3515412B1 (en) * | 2016-09-23 | 2025-04-23 | Grünenthal GmbH | Stable formulation for parenteral administration of tapentadol |
| EP3585370A1 (en) | 2017-02-23 | 2020-01-01 | Grünenthal GmbH | Tapentadol as local anesthetic |
| CN113825500A (zh) * | 2019-05-16 | 2021-12-21 | 奈克瑟斯药物公司 | 包含麻黄碱或麻黄碱盐的组合物及其制备和使用方法 |
| EP4011369A1 (en) * | 2020-12-14 | 2022-06-15 | G.L. Pharma GmbH | Aqueous pharmaceutical composition comprising tapentadol tartrate |
| CN114788814B (zh) * | 2021-01-26 | 2023-10-13 | 浙江创新生物有限公司 | 一种高稳定性的注射用达托霉素组合物及其制备方法和其应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8334422D0 (en) * | 1983-12-23 | 1984-02-01 | Sterwin Ag | Composition |
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| CN1227258C (zh) * | 2000-04-27 | 2005-11-16 | 辉瑞产品公司 | 氮杂大环内酯抗生素组合物在治疗或预防哺乳动物细菌或原生动物感染中的应用 |
| AU2001222986A1 (en) * | 2000-05-19 | 2001-12-03 | Progenics Pharmaceuticals, Inc. | Dehydroascorbic acid formulations and uses thereof |
| US6399087B1 (en) * | 2000-12-20 | 2002-06-04 | Amphastar Pharmaceuticals, Inc. | Propofol formulation with enhanced microbial inhibition |
| DE10109763A1 (de) * | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| JP4905616B2 (ja) * | 2001-04-19 | 2012-03-28 | ライオン株式会社 | ソフトコンタクトレンズ用点眼剤 |
| PE20030527A1 (es) | 2001-10-24 | 2003-07-26 | Gruenenthal Chemie | Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen |
| US20030191187A1 (en) * | 2002-04-01 | 2003-10-09 | Lee Fang Yu | Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same |
| US20040180915A1 (en) * | 2003-03-14 | 2004-09-16 | Xanodyne Pharmacal, Inc. | Methadone-containing compositions for parenteral administration and method of use thereof |
| DE602004007905T2 (de) * | 2004-06-28 | 2008-05-08 | Grünenthal GmbH | Kristalline Formen von (-)-(1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochlorid |
| PL1786403T3 (pl) | 2004-07-01 | 2013-10-31 | Gruenenthal Gmbh | Doustna postać dawki zabezpieczona przed nadużywaniem zawierająca (1R, 2R)-3-(3-dimetyloamino-1-etylo0-2-metylo-propylo)fenol |
| AU2006239313A1 (en) * | 2005-04-28 | 2006-11-02 | Najib Babul | Methods and compositions for treating pain |
| MX2008007075A (es) * | 2005-12-02 | 2008-11-12 | Mdrna Inc | Formulacion farmaceutica para incrementar la permeabilidad epitelial por peptido regulador de glucosa. |
| EP2012764B1 (en) * | 2006-04-28 | 2011-01-12 | Grünenthal GmbH | Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol |
| MX2008013828A (es) | 2006-04-28 | 2008-11-10 | Gruenenthal Gmbh | Combinacion farmaceutica que comprende 3-(3-dimetilanimo-1-etil-2- metil-propil)-fenol y un nsaid. |
| SI2046726T1 (sl) * | 2006-07-24 | 2010-05-31 | Janssen Pharmaceutica Nv | Priprava R R metoksifenil N N trimetilpentanamina |
| EP1905440A1 (de) * | 2006-09-06 | 2008-04-02 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verwendung einer pharmazeutischen Zusammensetzung enthaltend ein Anticholinergikum zur Abtötung von Mikroorganismen und zur Behandlung von Atemwegsinfektionen |
| TWI394564B (zh) * | 2006-09-21 | 2013-05-01 | Alcon Res Ltd | 自行保存型水性藥學組成物 |
| DE102007012165A1 (de) * | 2007-03-12 | 2008-09-18 | Grünenthal GmbH | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie des Neuropathieschmerzes |
| JP2008266168A (ja) * | 2007-04-18 | 2008-11-06 | Teika Seiyaku Kk | 眼科用剤 |
| EP1985292A1 (en) * | 2007-04-23 | 2008-10-29 | Grünenthal GmbH | Titration of tapentadol |
| WO2009067703A2 (en) | 2007-11-23 | 2009-05-28 | Nectid, Inc. | Tapentadol compositions |
| KR101616246B1 (ko) | 2008-01-25 | 2016-05-02 | 그뤼넨탈 게엠베하 | 약제학적 투여형 |
| LT2735338T (lt) * | 2008-09-05 | 2019-04-10 | Grünenthal GmbH | 3-(3-dimetilamino-1-etil-2-metil-propil)-fenolio ir pregabalino arba gabapentino farmacinis derinys |
| EP2246044A1 (en) * | 2009-04-21 | 2010-11-03 | Pierre Fabre Dermo-Cosmétique | Paediatric solutions comprising a beta-blocker |
| US20100272815A1 (en) * | 2009-04-28 | 2010-10-28 | Actavis Group Ptc Ehf | Amorphous form of tapentadol hydrochloride |
| CN101961315B (zh) * | 2010-09-10 | 2012-09-05 | 海南美兰史克制药有限公司 | 一种门冬氨酸鸟氨酸脂质体注射液 |
-
2012
- 2012-03-02 EA EA201600088A patent/EA028149B1/ru not_active IP Right Cessation
- 2012-03-02 US US13/410,945 patent/US20120225951A1/en not_active Abandoned
- 2012-03-02 EP EP15200814.0A patent/EP3025710A1/en not_active Withdrawn
- 2012-03-02 ES ES12709792.1T patent/ES2573414T3/es active Active
- 2012-03-02 EP EP12709792.1A patent/EP2680833B1/en active Active
- 2012-03-02 BR BR112013022213A patent/BR112013022213A2/pt not_active Application Discontinuation
- 2012-03-02 DK DK12709792.1T patent/DK2680833T3/en active
- 2012-03-02 KR KR1020187015692A patent/KR101970468B1/ko not_active Expired - Fee Related
- 2012-03-02 CN CN201280011685.9A patent/CN103501775A/zh active Pending
- 2012-03-02 MX MX2013010046A patent/MX348831B/es active IP Right Grant
- 2012-03-02 PT PT127097921T patent/PT2680833E/pt unknown
- 2012-03-02 HU HUE12709792A patent/HUE027514T2/en unknown
- 2012-03-02 HR HRP20160400TT patent/HRP20160400T1/hr unknown
- 2012-03-02 RS RS20160287A patent/RS54711B1/sr unknown
- 2012-03-02 JP JP2013555797A patent/JP2014510067A/ja active Pending
- 2012-03-02 PL PL12709792T patent/PL2680833T3/pl unknown
- 2012-03-02 WO PCT/EP2012/000905 patent/WO2012119728A1/en not_active Ceased
- 2012-03-02 EA EA201300990A patent/EA024193B1/ru not_active IP Right Cessation
- 2012-03-02 SI SI201230554A patent/SI2680833T1/sl unknown
- 2012-03-02 KR KR1020137026184A patent/KR101903351B1/ko not_active Expired - Fee Related
- 2012-03-02 CN CN201710217173.2A patent/CN107088226A/zh active Pending
- 2012-03-02 AU AU2012224953A patent/AU2012224953C1/en not_active Ceased
- 2012-03-02 CA CA2828635A patent/CA2828635C/en not_active Expired - Fee Related
-
2013
- 2013-08-06 IL IL227825A patent/IL227825A/en active IP Right Grant
- 2013-08-28 ZA ZA2013/06479A patent/ZA201306479B/en unknown
-
2015
- 2015-12-28 US US14/981,223 patent/US20160106688A1/en not_active Abandoned
-
2016
- 2016-04-11 CY CY20161100291T patent/CY1117426T1/el unknown
-
2017
- 2017-04-04 AU AU2017202214A patent/AU2017202214B2/en not_active Ceased
- 2017-08-21 JP JP2017158324A patent/JP6837944B2/ja not_active Expired - Fee Related
-
2020
- 2020-03-13 US US16/818,275 patent/US20200215003A1/en not_active Abandoned
-
2021
- 2021-12-01 JP JP2021195330A patent/JP2022033863A/ja active Pending
-
2023
- 2023-03-10 JP JP2023037505A patent/JP2023075244A/ja active Pending
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