JP2014510055A - ホスホジエステラーゼ１０（ｐｄｅ１０ａ）阻害剤としての置換６，７−ジアルコキシ−３−イソキノリノール誘導体 - Google Patents
ホスホジエステラーゼ１０（ｐｄｅ１０ａ）阻害剤としての置換６，７−ジアルコキシ−３−イソキノリノール誘導体 Download PDFInfo
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- JP2014510055A JP2014510055A JP2013554657A JP2013554657A JP2014510055A JP 2014510055 A JP2014510055 A JP 2014510055A JP 2013554657 A JP2013554657 A JP 2013554657A JP 2013554657 A JP2013554657 A JP 2013554657A JP 2014510055 A JP2014510055 A JP 2014510055A
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- methyl
- disorder
- dimethoxy
- dihydrochloride
- isoquinolin
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- OVCXRBARSPBVMC-UHFFFAOYSA-N triazolopyridine Chemical compound C=1N2C(C(C)C)=NN=C2C=CC=1C=1OC=NC=1C1=CC=C(F)C=C1 OVCXRBARSPBVMC-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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| US201161444566P | 2011-02-18 | 2011-02-18 | |
| US61/444,566 | 2011-02-18 | ||
| PCT/US2012/025731 WO2012112946A1 (en) | 2011-02-18 | 2012-02-17 | Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
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| EP (1) | EP2675791B1 (enExample) |
| JP (1) | JP2014510055A (enExample) |
| KR (1) | KR20140009372A (enExample) |
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| CA (1) | CA2827724A1 (enExample) |
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Cited By (1)
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| JP2019509267A (ja) * | 2016-02-12 | 2019-04-04 | アステラス製薬株式会社 | テトラヒドロイソキノリン誘導体 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG192839A1 (en) | 2011-02-18 | 2013-09-30 | Allergan Inc | Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
| WO2014071044A1 (en) | 2012-11-01 | 2014-05-08 | Allergan, Inc. | Substituted 6,7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
| US9200016B2 (en) | 2013-12-05 | 2015-12-01 | Allergan, Inc. | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) |
| JP6272604B2 (ja) * | 2013-12-27 | 2018-01-31 | 日本サプリメント株式会社 | 糖取り込み促進剤 |
| CN104370813A (zh) * | 2014-10-22 | 2015-02-25 | 上海大学 | 异喹啉-6-甲醛的制备方法 |
| ES2837396T3 (es) | 2016-11-23 | 2021-06-30 | Bayer Cropscience Ag | Derivados de 2-[3-(alquilsulfonil)-2H-indazol-2-il]-3H-imidazo[4,5-b]piridina y compuestos similares como pesticidas |
| US12234217B2 (en) | 2018-12-03 | 2025-02-25 | Fmc Corporation | Method for preparing N-phenylpyrazole-1-carboxamides |
| CN113376287A (zh) * | 2021-06-15 | 2021-09-10 | 劲牌有限公司 | 基于高效液相色谱法检测环核苷酸磷酸二酯酶抑制剂活性的方法 |
| WO2025149629A1 (en) | 2024-01-12 | 2025-07-17 | Syngenta Crop Protection Ag | Novel carboxamide compounds |
| WO2026008750A1 (en) | 2024-07-05 | 2026-01-08 | Syngenta Crop Protection Ag | Novel carboxamide compounds |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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- 2012-02-17 AU AU2012219316A patent/AU2012219316A1/en not_active Abandoned
- 2012-02-17 JP JP2013554657A patent/JP2014510055A/ja active Pending
- 2012-02-17 WO PCT/US2012/025731 patent/WO2012112946A1/en not_active Ceased
- 2012-02-17 BR BR112013021180A patent/BR112013021180A2/pt not_active IP Right Cessation
- 2012-02-17 RU RU2013142364/04A patent/RU2013142364A/ru not_active Application Discontinuation
- 2012-02-17 CA CA2827724A patent/CA2827724A1/en not_active Abandoned
- 2012-02-17 CN CN2012800184663A patent/CN103476757A/zh active Pending
- 2012-02-17 KR KR1020137024525A patent/KR20140009372A/ko not_active Withdrawn
- 2012-02-17 US US13/399,351 patent/US8772316B2/en active Active
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| EP2675791A1 (en) | 2013-12-25 |
| US9670181B2 (en) | 2017-06-06 |
| KR20140009372A (ko) | 2014-01-22 |
| MX2013009575A (es) | 2014-10-14 |
| WO2012112946A1 (en) | 2012-08-23 |
| BR112013021180A2 (pt) | 2019-09-24 |
| RU2013142364A (ru) | 2015-03-27 |
| IL228008A0 (en) | 2013-09-30 |
| CN103476757A (zh) | 2013-12-25 |
| US20140309253A1 (en) | 2014-10-16 |
| SG192839A1 (en) | 2013-09-30 |
| ZA201306416B (en) | 2014-04-30 |
| EP2675791B1 (en) | 2016-02-17 |
| CL2013002394A1 (es) | 2014-07-04 |
| CA2827724A1 (en) | 2012-08-23 |
| US20120214837A1 (en) | 2012-08-23 |
| AU2012219316A1 (en) | 2013-10-03 |
| US8772316B2 (en) | 2014-07-08 |
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