JP2014505662A - ジフェニル−アミン誘導体:使用、合成方法および医薬組成物 - Google Patents
ジフェニル−アミン誘導体:使用、合成方法および医薬組成物 Download PDFInfo
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- JP2014505662A JP2014505662A JP2013539296A JP2013539296A JP2014505662A JP 2014505662 A JP2014505662 A JP 2014505662A JP 2013539296 A JP2013539296 A JP 2013539296A JP 2013539296 A JP2013539296 A JP 2013539296A JP 2014505662 A JP2014505662 A JP 2014505662A
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- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/28—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by unsaturated carbon chains
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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| PCT/EP2011/070620 WO2012069442A1 (en) | 2010-11-23 | 2011-11-22 | Diphenyl-amine derivatives: uses, process of synthesis and pharmaceutical compositions |
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| RS51423B (sr) | 2006-03-31 | 2011-02-28 | Janssen Pharmaceutica N.V. | Benzoimidazol-2-il pirimidini i pirazini kao modulatori histaminskog h4 receptora |
| US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
| JO3516B1 (ar) | 2013-03-06 | 2020-07-05 | Janssen Pharmaceutica Nv | مُعدِّلات بنزإيميدازول-2-يل بيريميدين لمستقبل الهستامين h4 |
| KR101694318B1 (ko) * | 2014-10-02 | 2017-01-09 | 한국과학기술연구원 | 신규한 퓨린 유도체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
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| GB682160A (en) * | 1948-10-18 | 1952-11-05 | Wellcome Found | Improvements in and relating to the preparation of substituted aminoalcohols, alkenylamines, aminoalkanes and quaternary salts thereof |
| US5795756A (en) * | 1995-12-11 | 1998-08-18 | Johnson; Roger A. | Method and compounds for the inhibition of adenylyl cyclase |
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| CA2243330A1 (en) * | 1996-01-20 | 1997-07-24 | Ioana Popa | Tamoxifen and analogues thereof |
| DE19756261A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide |
| EP1375502B1 (en) | 2001-04-05 | 2007-06-13 | Sumitomo Chemical Company, Limited | Process for producing 2,6-dihalogenopurine |
| US20050065171A1 (en) | 2003-06-25 | 2005-03-24 | Shakespeare William C. | Substituted purine derivatives |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB682160A (en) * | 1948-10-18 | 1952-11-05 | Wellcome Found | Improvements in and relating to the preparation of substituted aminoalcohols, alkenylamines, aminoalkanes and quaternary salts thereof |
| US5795756A (en) * | 1995-12-11 | 1998-08-18 | Johnson; Roger A. | Method and compounds for the inhibition of adenylyl cyclase |
Non-Patent Citations (2)
| Title |
|---|
| JPN6015026661; Caldirola, P.; Zandberg, P.; Mannhold, R.; Timmerman, H.: 'New prenylamine-analogs: investigations of their influence on calcium-dependent biological systems' EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 28(7-8), 1993, 555-68 * |
| JPN6015026662; Kragler, Andrea; Hoefner, Georg; Wanner, Klaus T.: 'Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GAB' EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 43(11), 2008, 2404-2411 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017072839A (ja) * | 2011-04-20 | 2017-04-13 | マッパー・リソグラフィー・アイピー・ビー.ブイ. | 光ファイバの構成体及びこのような構成体を形成する方法 |
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| CO6771413A2 (es) | 2013-10-15 |
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| CL2013001445A1 (es) | 2014-03-28 |
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| US20130296346A1 (en) | 2013-11-07 |
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| MA34746B1 (fr) | 2013-12-03 |
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| EP2465498A1 (en) | 2012-06-20 |
| CA2818842A1 (en) | 2012-05-31 |
| CN103313707A (zh) | 2013-09-18 |
| MX2013005761A (es) | 2013-09-26 |
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