JP2014505074A - 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 - Google Patents

血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 Download PDF

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Publication number
JP2014505074A
JP2014505074A JP2013551327A JP2013551327A JP2014505074A JP 2014505074 A JP2014505074 A JP 2014505074A JP 2013551327 A JP2013551327 A JP 2013551327A JP 2013551327 A JP2013551327 A JP 2013551327A JP 2014505074 A JP2014505074 A JP 2014505074A
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JP
Japan
Prior art keywords
μmol
esmolol
phenylpropionate
propoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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JP2013551327A
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English (en)
Japanese (ja)
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JP2014505074A5 (https=
Inventor
バレット ラビナウ，
ジェフ マッキー，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare SA
Baxter International Inc
Original Assignee
Baxter Healthcare SA
Baxter International Inc
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Publication date
Application filed by Baxter Healthcare SA, Baxter International Inc filed Critical Baxter Healthcare SA
Publication of JP2014505074A publication Critical patent/JP2014505074A/ja
Publication of JP2014505074A5 publication Critical patent/JP2014505074A5/ja
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013551327A 2011-01-27 2012-01-26 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法 Withdrawn JP2014505074A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161436992P 2011-01-27 2011-01-27
US61/436,992 2011-01-27
PCT/US2012/022696 WO2012103314A1 (en) 2011-01-27 2012-01-26 Methods of treating tachycardia and/or controlling heart rate while minimizing and/or controlling hypotension

Publications (2)

Publication Number Publication Date
JP2014505074A true JP2014505074A (ja) 2014-02-27
JP2014505074A5 JP2014505074A5 (https=) 2015-03-19

Family

ID=45567141

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013551327A Withdrawn JP2014505074A (ja) 2011-01-27 2012-01-26 血圧低下を最小化しおよび／または制御しながら頻脈を治療しおよび／または心拍数を制御する方法

Country Status (10)

Country Link
US (2) US8686036B2 (https=)
EP (1) EP2667867B1 (https=)
JP (1) JP2014505074A (https=)
KR (1) KR20140034729A (https=)
CN (1) CN103338763A (https=)
AU (1) AU2012211318C1 (https=)
BR (1) BR112013016701A2 (https=)
CA (1) CA2825311A1 (https=)
MX (1) MX2013008713A (https=)
WO (1) WO2012103314A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013018598A2 (pt) 2011-01-27 2016-10-18 Baxter Healthcare Sa composição farmacêutica, método para tratar uma doença cardíaca, uso de (s)-metil-3-[4-(2-hidroxi-3-[4-(2-hidroxi-3-isopropilamino) propoxi] fenilpropionato, e, método para controlar frequência cardíaca
RU2613564C1 (ru) * 2015-12-02 2017-03-17 федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Западный государственный медицинский университет имени И.И. Мечникова" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СЗГМУ им. И.И. Мечникова Минздрава России) Способ прогнозирования интраоперационной артериальной гипотензии при проведении анестезии

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179808B1 (en) 1984-04-09 1991-10-30 The Du Pont Merck Pharmaceutical Company Pharmaceutical composition suitable for treatment or prophylaxis of cardiac disorders
EP0248879A4 (en) * 1985-12-04 1990-02-26 Du Pont PRODUCTION OF ARYLOXYPROPANOLAMINES AND ARYLÄTHANOLAMINES.
EP0279844A4 (en) 1986-09-02 1990-06-05 Du Pont AFLÖSUNG VON DE dl-METHYL-3-4- (2-HYDROXY-3-ISOPROPYLAMINO) PROPOXY] PHENYLPROPIONAT (DL-ESMOLOL)].
US4857552A (en) * 1988-06-08 1989-08-15 E. I. Du Pont De Nemours And Co. Stable pharmaceutical composition
US5849843A (en) 1993-11-16 1998-12-15 Baxter International Inc. Polymeric compositions for medical packaging and devices
US5998019A (en) 1993-11-16 1999-12-07 Baxter International Inc. Multi-layered polymer structure for medical products
US5977409A (en) 1997-04-15 1999-11-02 University Of Toledo Method of using α-substituted benzylamine chiral auxiliary synthetic reagents
US6310094B1 (en) 2001-01-12 2001-10-30 Baxter International Inc. Ready-to-use esmolol solution
TWI277414B (en) 2001-01-12 2007-04-01 Baxter Int Esmolol formulation
JP4816083B2 (ja) * 2003-08-08 2011-11-16 小野薬品工業株式会社 短時間型β遮断薬を有効成分とする心拍数減少剤
US20080293814A1 (en) 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
CN101323580A (zh) 2008-07-25 2008-12-17 河北科技大学 手性芳氧丙醇胺类化合物及其盐的合成方法
CN101881755B (zh) 2009-05-04 2013-05-29 南京海辰药业有限公司 通过高效液相色谱法检测盐酸艾司洛尔光学异构体的方法
CN101891636A (zh) 2009-05-21 2010-11-24 南京海辰药业有限公司 制备盐酸艾司洛尔光学异构体的新方法
CN102106846A (zh) 2009-12-23 2011-06-29 南京海辰药业有限公司 左旋盐酸艾司洛尔药物组合物及其制备方法
BR112013018598A2 (pt) 2011-01-27 2016-10-18 Baxter Healthcare Sa composição farmacêutica, método para tratar uma doença cardíaca, uso de (s)-metil-3-[4-(2-hidroxi-3-[4-(2-hidroxi-3-isopropilamino) propoxi] fenilpropionato, e, método para controlar frequência cardíaca

Also Published As

Publication number Publication date
EP2667867B1 (en) 2015-05-27
KR20140034729A (ko) 2014-03-20
US20140066503A1 (en) 2014-03-06
MX2013008713A (es) 2013-08-29
US9084763B2 (en) 2015-07-21
AU2012211318C1 (en) 2016-08-04
US8686036B2 (en) 2014-04-01
WO2012103314A1 (en) 2012-08-02
BR112013016701A2 (pt) 2017-07-04
CN103338763A (zh) 2013-10-02
AU2012211318B2 (en) 2016-01-28
AU2012211318A1 (en) 2013-05-02
US20120302637A1 (en) 2012-11-29
CA2825311A1 (en) 2012-08-02
EP2667867A1 (en) 2013-12-04

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