JP2014505049A5 - - Google Patents
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- Publication number
- JP2014505049A5 JP2014505049A5 JP2013547780A JP2013547780A JP2014505049A5 JP 2014505049 A5 JP2014505049 A5 JP 2014505049A5 JP 2013547780 A JP2013547780 A JP 2013547780A JP 2013547780 A JP2013547780 A JP 2013547780A JP 2014505049 A5 JP2014505049 A5 JP 2014505049A5
- Authority
- JP
- Japan
- Prior art keywords
- ccr2
- pharmaceutically acceptable
- acceptable salt
- angiotensin receptor
- pathway inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011900060 | 2011-01-11 | ||
| AU2011900060A AU2011900060A0 (en) | 2011-01-11 | Combination Therapy | |
| AU2011904279 | 2011-10-17 | ||
| AU2011904279A AU2011904279A0 (en) | 2011-10-17 | Combination Therapy | |
| PCT/AU2012/000014 WO2012094703A1 (en) | 2011-01-11 | 2012-01-11 | Combination therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016247754A Division JP2017078085A (ja) | 2011-01-11 | 2016-12-21 | 併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014505049A JP2014505049A (ja) | 2014-02-27 |
| JP2014505049A5 true JP2014505049A5 (enExample) | 2015-02-19 |
| JP6087836B2 JP6087836B2 (ja) | 2017-03-01 |
Family
ID=46506697
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013547780A Active JP6087836B2 (ja) | 2011-01-11 | 2012-01-11 | 併用療法 |
| JP2016247754A Pending JP2017078085A (ja) | 2011-01-11 | 2016-12-21 | 併用療法 |
| JP2018101282A Pending JP2018127498A (ja) | 2011-01-11 | 2018-05-28 | 併用療法 |
| JP2020084905A Pending JP2020122015A (ja) | 2011-01-11 | 2020-05-14 | 併用療法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016247754A Pending JP2017078085A (ja) | 2011-01-11 | 2016-12-21 | 併用療法 |
| JP2018101282A Pending JP2018127498A (ja) | 2011-01-11 | 2018-05-28 | 併用療法 |
| JP2020084905A Pending JP2020122015A (ja) | 2011-01-11 | 2020-05-14 | 併用療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US9314450B2 (enExample) |
| EP (3) | EP3586844A1 (enExample) |
| JP (4) | JP6087836B2 (enExample) |
| CN (2) | CN103476410B (enExample) |
| AU (1) | AU2012206945B2 (enExample) |
| CA (1) | CA2821985C (enExample) |
| IL (1) | IL227414A (enExample) |
| WO (1) | WO2012094703A1 (enExample) |
| ZA (1) | ZA201305897B (enExample) |
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|---|---|---|---|---|
| EP2547366A4 (en) | 2010-03-18 | 2013-08-07 | Univ Colorado State Res Found | SUPPRESSOR CELL HEMMER OBTAINED FROM MYELOID CELLS |
| EP2726108B1 (en) | 2011-06-29 | 2018-01-10 | The Trustees of Columbia University in the City of New York | Inhibitor of neuronal connectivity linked to schizophrenia susceptibility and cognitive dysfunction |
| WO2014021942A1 (en) * | 2012-08-01 | 2014-02-06 | University Of Southern California | Methods for limiting development of neurodegeneration |
| WO2014075093A1 (en) * | 2012-11-09 | 2014-05-15 | The Trustees Of Columbia University In The City Of New York | Inhibitors of central nervous system vasoactive inhibitory peptide receptor 2 |
| JP2014193854A (ja) * | 2013-02-28 | 2014-10-09 | Santen Pharmaceut Co Ltd | テトラヒドロピラニルアミノシクロペンチルカルボニルテトラヒドロピリドピリジン誘導体を有効成分として含有する後眼部疾患の予防または治療剤 |
| US8975290B2 (en) | 2013-03-01 | 2015-03-10 | Colorado State University Research Foundation | Methods and compositions for enhancing an immune response, blocking monocyte migration, amplifying vaccine immunity and inhibiting tumor growth and metastasis |
| WO2014134621A2 (en) * | 2013-03-01 | 2014-09-04 | Colorado State University Research Foundation | Methods and compositions for enhancing an immune response, blocking monocyte migration, amplifying vaccine immunity and inhibiting tumor growth and metastasis |
| CN103193771B (zh) * | 2013-03-29 | 2015-08-05 | 中国人民解放军军事医学科学院生物工程研究所 | 链状酰胺类ccr5受体抑制剂的药物新用途 |
| US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
| US10561676B2 (en) * | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
| MX2017000580A (es) * | 2014-07-17 | 2017-09-01 | Santen Pharmaceutical Co Ltd | Agente profilactico o terapeutico para enfermedades del segmento posterior del ojo. |
| AU2015314830B2 (en) * | 2014-09-12 | 2021-01-07 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
| EP3349751A4 (en) * | 2015-09-16 | 2019-05-22 | Tobira Therapeutics, Inc. | CENICRIVIROC COMBINATION THERAPY FOR THE TREATMENT OF FIBROSIS |
| ES2907489T3 (es) | 2015-12-14 | 2022-04-25 | X4 Pharmaceuticals Inc | Métodos para el tratamiento del cáncer |
| EP3389652B1 (en) | 2015-12-14 | 2022-09-28 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| ES2935834T3 (es) | 2015-12-22 | 2023-03-10 | X4 Pharmaceuticals Inc | Métodos para tratar enfermedad de inmunodeficiencia |
| CN109153722A (zh) | 2016-04-08 | 2019-01-04 | X4 制药有限公司 | 用于治疗癌症的方法 |
| EP3471726A4 (en) | 2016-06-21 | 2019-10-09 | X4 Pharmaceuticals, Inc. | CXCR4 INHIBITORS AND USES THEREOF |
| WO2017223243A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| JP7054529B2 (ja) | 2016-06-21 | 2022-04-14 | エックス4 ファーマシューティカルズ, インコーポレイテッド | Cxcr4阻害剤およびその使用 |
| EP4134080B1 (en) | 2016-11-23 | 2024-11-13 | ChemoCentryx, Inc. | Ccr2 inhibitors for use in treating renal diseases |
| MX386699B (es) | 2017-10-11 | 2025-03-19 | Chemocentryx Inc | Tratamiento de glomerulosclerosis segmentaria focal con antagonistas ccr2 |
| CN108218789A (zh) * | 2018-03-12 | 2018-06-29 | 钦州学院 | 碳13氘代甲基替米沙坦及其制备方法和用途 |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| JP7501876B2 (ja) * | 2019-04-17 | 2024-06-18 | 国立大学法人広島大学 | Il-6阻害剤及びccr2阻害剤を組み合わせて投与することを特徴とする泌尿器がんの治療剤 |
| CN114466653A (zh) * | 2019-09-26 | 2022-05-10 | 戴麦里克斯生物科学有限公司 | 用于治疗疾病的方法和组合物 |
| WO2021183650A1 (en) | 2020-03-10 | 2021-09-16 | X4 Pharmaceuticals, Inc. | Methods for treating neutropenia |
| GB202006079D0 (en) * | 2020-04-24 | 2020-06-10 | Vicore Pharma Ab | New composition |
| EP4146191A1 (en) * | 2020-05-06 | 2023-03-15 | Dimerix Bioscience Pty Ltd | Treatment for acute respiratory distress syndrome |
| WO2021222971A1 (en) * | 2020-05-06 | 2021-11-11 | Dimerix Bioscience Ltd | Treatment for virus induced acute respiratory distress syndrome |
| CN117042763A (zh) * | 2021-03-23 | 2023-11-10 | 戴麦里克斯生物科学有限公司 | 炎性疾病的治疗 |
| WO2024026528A1 (en) * | 2022-08-02 | 2024-02-08 | Dimerix Bioscience Pty Ltd | Dosage regimen for the treatment of copd |
| TW202444344A (zh) * | 2023-05-12 | 2024-11-16 | 澳大利亞商迪美力士生物科技有限公司 | 用於腎病之治療調配物 |
| CN117054652B (zh) * | 2023-08-04 | 2024-05-17 | 南京医科大学 | 一种用于辅助检测心肌肥厚的生物标志物及其应用 |
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| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US4671958A (en) | 1982-03-09 | 1987-06-09 | Cytogen Corporation | Antibody conjugates for the delivery of compounds to target sites |
| US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| JP2876058B2 (ja) | 1986-08-18 | 1999-03-31 | エミスフィア・テクノロジーズ・インコーポレイテッド | 薬物送達システム |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5821232A (en) * | 1990-05-11 | 1998-10-13 | Pfizer Inc. | Synergistic therapeutic compositions and methods |
| US5492904A (en) * | 1991-05-15 | 1996-02-20 | E. I. Du Pont De Nemours And Company | Composition of angiotensin-II receptor antagonists and calcium channel blockers |
| JPH059116A (ja) | 1991-07-01 | 1993-01-19 | Sanwa Kagaku Kenkyusho Co Ltd | 3−オキシゲルミルプロピオン酸組成物並びに該組成物を主成分とする細胞変性抑制剤 |
| PT831911E (pt) * | 1995-06-07 | 2002-09-30 | Searle & Co | Terapeutica de combinacao de espironolactona e antagonista da angiotensina ii para o tratamento de insuficiencia cardiaca congestiva |
| US5891646A (en) | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
| WO2000025134A1 (en) | 1998-10-23 | 2000-05-04 | Glaxo Group Limited | Assays for ligands for nuclear receptors |
| DE60130538T2 (de) * | 2000-02-03 | 2008-06-12 | Millenium Pharmaceuticals, Inc., Cambridge | Humanisierte antikörper gegen ccr2 und verfahren zur deren verwendung |
| US6893827B1 (en) | 2000-02-07 | 2005-05-17 | Applera Corporation | Receptor function assay for G-protein coupled receptors and orphan receptors by reporter enzyme mutant complementation |
| WO2003014110A1 (en) * | 2001-08-08 | 2003-02-20 | Takeda Chemical Industries, Ltd. | Benzazepine derivative, process for producing the same, and use |
| DE10218785A1 (de) | 2002-04-26 | 2003-11-13 | Infineon Technologies Ag | Halbleiterspeichereinrichtung und Betriebsverfahren für eine Halbleiterspeichereinrichtung |
| JP2004093527A (ja) | 2002-09-04 | 2004-03-25 | Center For Advanced Science & Technology Incubation Ltd | 蛍光共鳴エネルギー転移を用いた蛋白質の分析方法 |
| EP1481996A1 (en) | 2003-05-30 | 2004-12-01 | KRATON Polymers Research B.V. | Process for making a coupled block copolymer composition |
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| JP2006008568A (ja) | 2004-06-24 | 2006-01-12 | Cyclochem:Kk | IgE抗体抑制剤および食品 |
| EP1787647B1 (en) * | 2004-09-06 | 2012-06-20 | Kowa Company, Ltd. | Remedy for glomerular diseases |
| AR050631A1 (es) | 2004-09-09 | 2006-11-08 | Novartis Ag | Combinacion de compuestos organicos |
| GB0612630D0 (en) * | 2006-06-26 | 2006-08-02 | Novartis Ag | Organic compounds |
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| WO2008113095A1 (en) | 2007-03-20 | 2008-09-25 | Fibrotech Therapeutics Pty Ltd | Compositions and therapies comprising tranilast compounds and angiotensin-converting enzyme (ace) inhibitors and/or angiotensin receptor blockers (arb) |
| KR20100087291A (ko) * | 2007-09-25 | 2010-08-04 | 아보트 러보러터리즈 | 케모카인 수용체 길항제로서의 옥타하이드로펜탈렌 화합물 |
| MX2010006089A (es) * | 2007-12-04 | 2010-09-22 | Schering Corp | Metodos de tratamiento de enfermedad pulmonar obstructiva cronica. |
| US20110092463A1 (en) | 2008-04-07 | 2011-04-21 | Johan Raud | Combination for use in the treatment of inflammatory disorders |
| EP2389178A4 (en) | 2008-12-01 | 2012-06-06 | Invasc Therapeutic Inc | COMPOSITIONS CONTAINING INHIBITORS OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AND LIPOIC ACID COMPOUNDS, AND THEIR USE FOR THE TREATMENT OF RENIN-ANGIOTENSIN-ALDOSTERONE ASSOCIATED DISORDERS |
| US8537791B2 (en) | 2009-01-20 | 2013-09-17 | Lg Electronics Inc. | Method and apparatus for channel access in contention-based communication system and station |
| US20120100130A1 (en) * | 2009-03-27 | 2012-04-26 | Dimerix Bioscience Pty Ltd. | Novel Receptor Hetero-Dimers/-Oligomers |
-
2012
- 2012-01-11 EP EP19186903.1A patent/EP3586844A1/en not_active Withdrawn
- 2012-01-11 CN CN201280004616.5A patent/CN103476410B/zh active Active
- 2012-01-11 WO PCT/AU2012/000014 patent/WO2012094703A1/en not_active Ceased
- 2012-01-11 AU AU2012206945A patent/AU2012206945B2/en active Active
- 2012-01-11 US US13/979,127 patent/US9314450B2/en active Active
- 2012-01-11 JP JP2013547780A patent/JP6087836B2/ja active Active
- 2012-01-11 CN CN201711107879.XA patent/CN107899012A/zh active Pending
- 2012-01-11 EP EP23161550.1A patent/EP4215194A1/en active Pending
- 2012-01-11 CA CA2821985A patent/CA2821985C/en active Active
- 2012-01-11 EP EP12734251.7A patent/EP2663304B1/en active Active
-
2013
- 2013-07-10 IL IL227414A patent/IL227414A/en active IP Right Grant
- 2013-08-06 ZA ZA2013/05897A patent/ZA201305897B/en unknown
-
2016
- 2016-03-31 US US15/086,823 patent/US10058555B2/en active Active
- 2016-12-21 JP JP2016247754A patent/JP2017078085A/ja active Pending
-
2017
- 2017-09-14 US US15/704,713 patent/US10525038B2/en active Active
-
2018
- 2018-05-28 JP JP2018101282A patent/JP2018127498A/ja active Pending
-
2019
- 2019-10-16 US US16/654,912 patent/US11382896B2/en active Active
-
2020
- 2020-05-14 JP JP2020084905A patent/JP2020122015A/ja active Pending
-
2022
- 2022-05-11 US US17/662,866 patent/US12083102B2/en active Active
-
2024
- 2024-07-16 US US18/774,024 patent/US20240366570A1/en active Pending
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