JP2014503575A5 - - Google Patents
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- Publication number
- JP2014503575A5 JP2014503575A5 JP2013550906A JP2013550906A JP2014503575A5 JP 2014503575 A5 JP2014503575 A5 JP 2014503575A5 JP 2013550906 A JP2013550906 A JP 2013550906A JP 2013550906 A JP2013550906 A JP 2013550906A JP 2014503575 A5 JP2014503575 A5 JP 2014503575A5
- Authority
- JP
- Japan
- Prior art keywords
- liposome
- measuring
- heating
- interest
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002502 liposome Substances 0.000 claims 27
- 239000012528 membrane Substances 0.000 claims 11
- 238000010438 heat treatment Methods 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 230000035699 permeability Effects 0.000 claims 6
- 150000002632 lipids Chemical class 0.000 claims 5
- 239000002105 nanoparticle Substances 0.000 claims 5
- 238000012544 monitoring process Methods 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 239000012736 aqueous medium Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 150000001735 carboxylic acids Chemical class 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 239000000824 cytostatic agent Chemical class 0.000 claims 1
- 230000001085 cytostatic effect Effects 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims 1
- 235000013980 iron oxide Nutrition 0.000 claims 1
- VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical class [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 235000021317 phosphate Nutrition 0.000 claims 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161437831P | 2011-01-31 | 2011-01-31 | |
| EP11305097.5 | 2011-01-31 | ||
| US61/437,831 | 2011-01-31 | ||
| EP11305097 | 2011-01-31 | ||
| PCT/EP2012/051510 WO2012104277A2 (en) | 2011-01-31 | 2012-01-31 | Method of monitoring the release from liposomes of a product of interest using superparamagnetic nanoparticles. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014503575A JP2014503575A (ja) | 2014-02-13 |
| JP2014503575A5 true JP2014503575A5 (https=) | 2015-03-12 |
Family
ID=44146997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013550906A Pending JP2014503575A (ja) | 2011-01-31 | 2012-01-31 | 超常磁性のナノ粒子を用いて、興味対象生成物のリポソームからの放出をモニターする方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20140227343A1 (https=) |
| EP (1) | EP2670393B8 (https=) |
| JP (1) | JP2014503575A (https=) |
| WO (1) | WO2012104277A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012104275A2 (en) | 2011-01-31 | 2012-08-09 | Nanobiotix | Nanoparticles delivery systems, preparation and uses thereof |
| EA029635B1 (ru) | 2011-12-16 | 2018-04-30 | Нанобиотикс | Применение наночастицы, включающей металлический материал, покрытый материалом оксида гафния, в онкологии и композиция, ее содержащая |
| RU2014133467A (ru) | 2012-02-17 | 2016-04-10 | Селшн Корпорейшн | Термочувствительные составы в виде наночастиц и способ их получения |
| WO2014191569A1 (en) | 2013-05-30 | 2014-12-04 | Nanobiotix | Pharmaceutical composition, preparation and uses thereof |
| KR20150026613A (ko) * | 2013-09-03 | 2015-03-11 | 삼성전자주식회사 | 소수성 물질 및 조영제를 포함하는 리포좀 및 그의 용도 |
| ES2543362B1 (es) * | 2014-01-15 | 2016-06-06 | Soluciones Nanotecnológicas, Sl | Composiciones que contienen liposomas, ácidos grasos poliinsaturados omega-3 de cadena larga y nanopartículas superparamagnéticas y su uso en el tratamiento de tumores malignos |
| SG11201704143YA (en) * | 2014-11-25 | 2017-06-29 | Nanobiotix | Pharmaceutical composition, preparation and uses thereof |
| UA123665C2 (uk) | 2014-11-25 | 2021-05-12 | Кюрадігм Сас | Фармацевтична композиція, її одержання і застосування |
| ES2774365T3 (es) | 2014-11-25 | 2020-07-20 | Curadigm Sas | Composición farmacéutica, preparación y usos de la misma |
| EP3229776B1 (en) | 2014-11-25 | 2023-06-28 | Curadigm Sas | Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof |
| EP3223796B1 (en) | 2014-11-25 | 2021-07-21 | Curadigm Sas | Pharmaceutical compositions, preparation and uses thereof |
| UA124572C2 (uk) | 2015-05-28 | 2021-10-13 | Нанобіотікс | Наночастинки для застосування як терапевтичної вакцини |
| EP3343573B1 (en) | 2015-08-28 | 2021-04-28 | Hunan Bohai New Materials Co., Ltd | Nano magneto-rheological fluid |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5395619A (en) * | 1993-03-03 | 1995-03-07 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
| DE19716732C2 (de) | 1997-03-07 | 1999-03-25 | Max Delbrueck Centrum | Spezifische Magnetosomen, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP0971692B1 (de) * | 1997-03-07 | 2003-03-05 | Max-Delbrück-Centrum Für Molekulare Medizin | Spezifische magnetosomen, verfahren zu ihrer herstellung und ihre verwendung |
| US6726925B1 (en) * | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
| US6200598B1 (en) * | 1998-06-18 | 2001-03-13 | Duke University | Temperature-sensitive liposomal formulation |
| US7769423B2 (en) * | 2002-09-11 | 2010-08-03 | Duke University | MRI imageable liposomes for the evaluation of treatment efficacy, thermal distribution, and demonstration of dose painting |
| JP2006051732A (ja) * | 2004-08-13 | 2006-02-23 | Panakku Kogyo Kk | 成形品から熱可塑性樹脂を回収する方法及び成形品 |
| WO2006051732A1 (ja) | 2004-11-10 | 2006-05-18 | Konica Minolta Medical & Graphic, Inc. | 被覆磁性粒子含有製剤およびその製造方法、並びに診断治療システム |
| NO329127B1 (no) * | 2006-09-12 | 2010-08-30 | Epitarget As | Sporbart partikulaert materiale for legemiddelavlevering omfattende et matriseeller membranmateriale, et legemiddel, og et T1- og et T2*- magnetisk resonanskontrastmiddel |
| NO20064315L (no) * | 2006-09-22 | 2008-03-24 | Epitarget As | T1 MRI-sporbare medikamentavleveringspartikler and anvendelse derav |
| US20090004258A1 (en) * | 2007-06-27 | 2009-01-01 | National Health Research Institutes | Drug Release from Thermosensitive Liposomes by Applying an Alternative Magnetic Field |
| EP2067485A1 (en) * | 2007-12-07 | 2009-06-10 | Koninklijke Philips Electronics N.V. | Drug carrier providing MRI contrast enhancement |
| EP2340051B1 (en) * | 2008-09-10 | 2015-11-11 | Koninklijke Philips N.V. | Drug carrier providing mri contrast enhancement |
| WO2012104275A2 (en) | 2011-01-31 | 2012-08-09 | Nanobiotix | Nanoparticles delivery systems, preparation and uses thereof |
-
2012
- 2012-01-31 EP EP12701899.2A patent/EP2670393B8/en not_active Not-in-force
- 2012-01-31 WO PCT/EP2012/051510 patent/WO2012104277A2/en not_active Ceased
- 2012-01-31 JP JP2013550906A patent/JP2014503575A/ja active Pending
- 2012-01-31 US US13/981,776 patent/US20140227343A1/en not_active Abandoned
-
2015
- 2015-10-19 US US14/886,326 patent/US10064962B2/en active Active
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