JP2014501492A5 - - Google Patents
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- Publication number
- JP2014501492A5 JP2014501492A5 JP2013532277A JP2013532277A JP2014501492A5 JP 2014501492 A5 JP2014501492 A5 JP 2014501492A5 JP 2013532277 A JP2013532277 A JP 2013532277A JP 2013532277 A JP2013532277 A JP 2013532277A JP 2014501492 A5 JP2014501492 A5 JP 2014501492A5
- Authority
- JP
- Japan
- Prior art keywords
- short rna
- strand
- rna
- short
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1016989.4A GB201016989D0 (en) | 2010-10-08 | 2010-10-08 | Cell induction |
| GB1016989.4 | 2010-10-08 | ||
| GBGB1103745.4A GB201103745D0 (en) | 2011-03-07 | 2011-03-07 | Cell induction |
| GB1103745.4 | 2011-03-07 | ||
| PCT/GB2011/051940 WO2012046084A2 (en) | 2010-10-08 | 2011-10-10 | Short rna molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501492A JP2014501492A (ja) | 2014-01-23 |
| JP2014501492A5 true JP2014501492A5 (OSRAM) | 2014-11-13 |
| JP5681955B2 JP5681955B2 (ja) | 2015-03-11 |
Family
ID=44860439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532277A Expired - Fee Related JP5681955B2 (ja) | 2010-10-08 | 2011-10-10 | 短いrna分子 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US8916534B2 (OSRAM) |
| EP (2) | EP2625272B1 (OSRAM) |
| JP (1) | JP5681955B2 (OSRAM) |
| KR (1) | KR20130132795A (OSRAM) |
| CN (1) | CN103314108B (OSRAM) |
| AU (1) | AU2011311344B2 (OSRAM) |
| CA (1) | CA2817191A1 (OSRAM) |
| WO (2) | WO2012046085A2 (OSRAM) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5681955B2 (ja) * | 2010-10-08 | 2015-03-11 | ミナ セラピューティクス リミテッド | 短いrna分子 |
| HRP20181124T1 (hr) | 2012-07-31 | 2018-11-02 | The Board Of Regents Of The University Of Texas System | Postupci i pripravci za in vivo indukciju nastajanja beta stanica gušterače |
| US10202601B2 (en) | 2013-11-22 | 2019-02-12 | Mina Therapeutics Limited | C/EBPα short activating RNA compositions and methods of use |
| US20170044540A1 (en) * | 2014-04-22 | 2017-02-16 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| WO2016170348A2 (en) * | 2015-04-22 | 2016-10-27 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| CN106480028B (zh) * | 2016-10-12 | 2019-04-05 | 上海市第七人民医院 | TPO基因的saRNA分子及其应用 |
| KR102771727B1 (ko) * | 2017-06-21 | 2025-02-26 | 티모시 에이. 버트람 | 신장 질환의 치료를 위한 면역특권화 생체활성 신장 세포 |
| KR102007457B1 (ko) | 2017-06-30 | 2019-08-05 | 동국대학교 산학협력단 | Cas9 단백질, 가이드 RNA 및 양친매성 펩타이드를 포함하는 나노복합체 및 이의 용도 |
| AU2018314236B2 (en) * | 2017-08-11 | 2025-02-06 | Apterna Limited | RNA aptamers against transferrin receptor (TfR) |
| US20200208152A1 (en) | 2017-09-08 | 2020-07-02 | Mina Therapeutics Limited | Stabilized sarna compositions and methods of use |
| WO2019048631A1 (en) | 2017-09-08 | 2019-03-14 | Mina Therapeutics Limited | SMALL HNF4A ACTIVATOR RNA COMPOSITIONS AND METHODS OF USE |
| JP7432521B2 (ja) * | 2018-04-10 | 2024-02-16 | ラクティゲン セラピューティクス | 新規小分子活性化rna |
| JP7495126B2 (ja) * | 2018-05-08 | 2024-06-04 | ユニヴァーシティー オブ マイアミ | 組織への治療用核酸の送達のための材料および方法 |
| AU2019285344A1 (en) | 2018-06-15 | 2020-12-10 | Mina Therapeutics Limited | Combination therapies comprising C/EBP alpha saRNA |
| JP2022545101A (ja) | 2019-08-19 | 2022-10-25 | ミナ セラピューティクス リミテッド | オリゴヌクレオチドコンジュゲート組成物および使用方法 |
| WO2022229644A1 (en) | 2021-04-28 | 2022-11-03 | Mina Therapeutics Limited | Combination therapies comprising c/ebp alpha sarna |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US8193330B2 (en) | 1999-04-06 | 2012-06-05 | The Regents Of The University Of California | Polynucleotides comprising Neurogenin3 promoter and bHLH encoding domains |
| KR20080023768A (ko) | 2000-03-30 | 2008-03-14 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | Rna 간섭의 rna 서열 특이적인 매개체 |
| GB0329449D0 (en) | 2003-12-19 | 2004-01-28 | Omnicyte Ltd | Stem cells |
| US8877721B2 (en) * | 2005-04-15 | 2014-11-04 | The Regents Of The University Of California | Small activating RNA molecules and methods of use |
| US8357666B2 (en) | 2005-08-01 | 2013-01-22 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through RNA interference |
| JP5066095B2 (ja) | 2005-11-17 | 2012-11-07 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 染色体dnaに標的化されるオリゴマーによる遺伝子発現の調節 |
| JP5713377B2 (ja) | 2005-12-28 | 2015-05-07 | ザ スクリプス リサーチ インスティテュート | 薬物標的としての天然アンチセンスおよび非コードrna転写物 |
| WO2008109556A1 (en) | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof |
| WO2008109449A1 (en) | 2007-03-02 | 2008-09-12 | Mdrna Inc. | Nucleic acid compounds for inhibiting bcl2 gene expression and uses thereof |
| JP2010528613A (ja) | 2007-05-29 | 2010-08-26 | クリストファー ビー. リード, | 多能細胞集団を産生する方法およびその使用 |
| WO2009046397A2 (en) * | 2007-10-04 | 2009-04-09 | Board Of Regents, The University Of Texas System | Modulating gene expression with agrna and gapmers targeting antisense transcripts |
| JP2011507554A (ja) | 2007-12-28 | 2011-03-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 遺伝子発現を増加させるための方法および組成物 |
| KR20110006672A (ko) | 2008-04-07 | 2011-01-20 | 뉴포텐셜, 인크. | Hdac 조절제의 사용을 통한 다능 유전자의 유도에 의한 세포 재프로그래밍 |
| WO2009126927A2 (en) | 2008-04-11 | 2009-10-15 | Joslin Diabetes Center, Inc. | Methods of generating insulin-producing cells |
| EP2363467B1 (en) | 2008-10-23 | 2015-12-16 | The University of Tokyo | Method for inhibiting function of micro-rna |
| NZ595273A (en) | 2008-11-13 | 2012-10-26 | Baylor Res Inst | Regeneration of pancreatic islets and reversal of diabetes by islet transcription factor genes delivered in vivo |
| WO2010108126A2 (en) | 2009-03-19 | 2010-09-23 | Fate Therapeutics, Inc. | Reprogramming compositions and methods of using the same |
| US8957037B2 (en) | 2009-05-18 | 2015-02-17 | Curna, Inc. | Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor |
| EP2456858B1 (en) | 2009-07-20 | 2018-08-29 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| JP5963680B2 (ja) * | 2010-01-06 | 2016-08-03 | カッパーアールエヌエー,インコーポレイテッド | 膵臓発生遺伝子に対する天然アンチセンス転写物の阻害による膵臓発生遺伝子疾患の治療 |
| GB201010557D0 (en) | 2010-06-23 | 2010-08-11 | Mina Therapeutics Ltd | RNA molecules and uses thereof |
| US8635602B2 (en) | 2010-07-26 | 2014-01-21 | International Business Machines Corporation | Verification of information-flow downgraders |
| JP5681955B2 (ja) * | 2010-10-08 | 2015-03-11 | ミナ セラピューティクス リミテッド | 短いrna分子 |
-
2011
- 2011-10-10 JP JP2013532277A patent/JP5681955B2/ja not_active Expired - Fee Related
- 2011-10-10 US US13/877,968 patent/US8916534B2/en active Active
- 2011-10-10 KR KR1020137011858A patent/KR20130132795A/ko not_active Withdrawn
- 2011-10-10 WO PCT/GB2011/051942 patent/WO2012046085A2/en not_active Ceased
- 2011-10-10 CN CN201180054998.8A patent/CN103314108B/zh active Active
- 2011-10-10 EP EP11774090.2A patent/EP2625272B1/en active Active
- 2011-10-10 AU AU2011311344A patent/AU2011311344B2/en active Active
- 2011-10-10 CA CA2817191A patent/CA2817191A1/en not_active Abandoned
- 2011-10-10 US US13/877,991 patent/US8835400B2/en active Active
- 2011-10-10 WO PCT/GB2011/051940 patent/WO2012046084A2/en not_active Ceased
- 2011-10-10 EP EP11826144.5A patent/EP2625273B1/en active Active
-
2014
- 2014-11-19 US US14/547,317 patent/US9885046B2/en active Active
-
2017
- 2017-12-11 US US15/837,377 patent/US10774331B2/en active Active
-
2020
- 2020-08-11 US US16/990,347 patent/US11365414B2/en active Active
-
2022
- 2022-05-17 US US17/746,387 patent/US20220282256A1/en not_active Abandoned
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