JP2014501267A - メサラジン制御放出用の経口用医薬錠剤および前記錠剤を得るための製法 - Google Patents

メサラジン制御放出用の経口用医薬錠剤および前記錠剤を得るための製法 Download PDF

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Publication number
JP2014501267A
JP2014501267A JP2013546690A JP2013546690A JP2014501267A JP 2014501267 A JP2014501267 A JP 2014501267A JP 2013546690 A JP2013546690 A JP 2013546690A JP 2013546690 A JP2013546690 A JP 2013546690A JP 2014501267 A JP2014501267 A JP 2014501267A
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JP
Japan
Prior art keywords
weight
tablet
present
oral pharmaceutical
mesalazine
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Pending
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JP2013546690A
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English (en)
Japanese (ja)
Inventor
ダビド、ロエチェス、ブラス
ロベルト、バラス、フェルナンデス‐モリナ
メルセデス、マルティネス、ペレス
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Laboratorios Liconsa SA
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Laboratorios Liconsa SA
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Application filed by Laboratorios Liconsa SA filed Critical Laboratorios Liconsa SA
Publication of JP2014501267A publication Critical patent/JP2014501267A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2013546690A 2010-12-27 2011-12-23 メサラジン制御放出用の経口用医薬錠剤および前記錠剤を得るための製法 Pending JP2014501267A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10382355.5 2010-12-27
EP10382355A EP2468264A1 (en) 2010-12-27 2010-12-27 Oral pharmaceutical tablet for controled release of mesalazine and process for obtaining it
PCT/EP2011/073983 WO2012089677A1 (en) 2010-12-27 2011-12-23 Oral pharmaceutical tablet for controled release of mesalazine and process for obtaining it

Publications (1)

Publication Number Publication Date
JP2014501267A true JP2014501267A (ja) 2014-01-20

Family

ID=43901549

Family Applications (1)

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JP2013546690A Pending JP2014501267A (ja) 2010-12-27 2011-12-23 メサラジン制御放出用の経口用医薬錠剤および前記錠剤を得るための製法

Country Status (17)

Country Link
US (1) US20130273156A1 (da)
EP (2) EP2468264A1 (da)
JP (1) JP2014501267A (da)
CN (1) CN103269691A (da)
BR (1) BR112013016461A2 (da)
CA (1) CA2822754A1 (da)
DK (1) DK2621477T3 (da)
ES (1) ES2463040T3 (da)
HK (1) HK1184391A1 (da)
HR (1) HRP20140479T1 (da)
PL (1) PL2621477T3 (da)
PT (1) PT2621477E (da)
RS (1) RS53363B (da)
RU (1) RU2013125148A (da)
SA (1) SA111330110B1 (da)
SI (1) SI2621477T1 (da)
WO (1) WO2012089677A1 (da)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018531960A (ja) * 2015-10-30 2018-11-01 ドクトル ファルク ファルマ ゲーエムベーハー 最適化高用量メサラジン含有錠剤
JP2019513800A (ja) * 2016-04-19 2019-05-30 フェリング ベスローテン フェンノートシャップ メサラジンの経口薬学的組成物
US11622938B2 (en) 2016-04-19 2023-04-11 Conaris Research Institute Ag Oral pharmaceutical compositions of nicotinamide

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105025888B (zh) * 2013-02-22 2018-10-12 志瑞亚新药工业株式会社 肠溶片
CN103211780B (zh) * 2013-04-17 2015-10-14 沈阳药科大学 美沙拉嗪口服结肠定位粘附微丸
PT3227273T (pt) 2014-12-02 2022-04-06 Minerva Neurosciences Inc Composições que compreendem 2-((1-(2(4-fluorofenil)-2-oxoetil)piperidin-4-il)metil)isoindolin-1-ona para tratamento de esquizofrenia
ITUB20160203A1 (it) * 2016-01-19 2017-07-19 Valpharma Int Spa Formulazioni in compresse a rilascio modificato contenenti Mesalazina ad alto dosaggio, processo per la loro preparazione e loro uso.
ITUA20162293A1 (it) * 2016-04-05 2017-10-05 Sofar Spa Processo per formulazioni solide di mesalazina
CN105902500B (zh) * 2016-04-27 2019-11-29 上海理工大学 一种美沙拉嗪肠溶定位控释制剂及其制备方法
US11464744B2 (en) * 2017-06-21 2022-10-11 Minerva Neurosciences, Inc. Gastro-resistant controlled release oral dosage forms
MX2021002017A (es) 2018-08-21 2021-04-28 Minerva Neurosciences Inc Uso de roluperidona para tratar sintomas y trastornos negativos, aumentar la neuroplasticidad y promover la neuroproteccion.
IT201800011120A1 (it) * 2018-12-14 2020-06-14 Dpl Pharma S P A Composizioni farmaceutiche orali solide per la somministrazione di mesalazina o suoi derivati
IT202000011050A1 (it) * 2020-05-14 2021-11-14 Mogon Pharmaceuticals Sagl Composizioni orali solide comprendenti matrici monolitiche composite per la somministrazione cronotropica nel tratto gastroenterico di ingredienti attivi

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002080398A (ja) * 2000-07-14 2002-03-19 Roberto Valducci ｐＨに依存する多相的な放出を伴う経口用の固体の薬学的組成物
WO2003011205A2 (en) * 2001-07-31 2003-02-13 Capricorn Pharma, Inc. Encapsulation products for controlled or extended release
JP2007509970A (ja) * 2003-10-29 2007-04-19 ワイス アプリンドルおよびその誘導体を含む持続放出型医薬組成物
JP2008504250A (ja) * 2004-06-28 2008-02-14 ソルベイ・フアーマシユーチカルズ・ベー・ブイ 胃貯留特性を有する経口用徐放性テジサミル製剤。
JP2008506668A (ja) * 2004-07-15 2008-03-06 ソルベイ・フアーマシユーチカルズ・ベー・ブイ ３−アミノ−８−（１−ピペラジニル）−２ｈ−１−ベンゾピラン−２−オンの長時間放出型調製物
JP2008074790A (ja) * 2006-09-22 2008-04-03 Nippon Chemiphar Co Ltd メサラジンを有効成分として含有する徐放性錠剤

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FR2692484B1 (fr) * 1992-06-22 1995-06-30 Gouchet Franck Nouvelle forme galenique de 4-asa a liberation controlee.
ITMI991316A1 (it) 1999-06-14 2000-12-14 Cip Ninety Two 92 S A Composizioni farmaceutiche orali a rilascio modificato di mesalazina
US20070059368A1 (en) * 2005-05-31 2007-03-15 Cherukuri S R Modified release formulations of anti-irritability drugs
AU2003225102A1 (en) * 2002-04-23 2003-11-10 Bristol-Myers Squibb Company Modified-release vasopeptidase inhibitor formulation, combinations and method
US7825106B2 (en) * 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002080398A (ja) * 2000-07-14 2002-03-19 Roberto Valducci ｐＨに依存する多相的な放出を伴う経口用の固体の薬学的組成物
WO2003011205A2 (en) * 2001-07-31 2003-02-13 Capricorn Pharma, Inc. Encapsulation products for controlled or extended release
JP2007509970A (ja) * 2003-10-29 2007-04-19 ワイス アプリンドルおよびその誘導体を含む持続放出型医薬組成物
JP2008504250A (ja) * 2004-06-28 2008-02-14 ソルベイ・フアーマシユーチカルズ・ベー・ブイ 胃貯留特性を有する経口用徐放性テジサミル製剤。
JP2008506668A (ja) * 2004-07-15 2008-03-06 ソルベイ・フアーマシユーチカルズ・ベー・ブイ ３−アミノ−８−（１−ピペラジニル）−２ｈ−１−ベンゾピラン−２−オンの長時間放出型調製物
JP2008074790A (ja) * 2006-09-22 2008-04-03 Nippon Chemiphar Co Ltd メサラジンを有効成分として含有する徐放性錠剤

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, vol. 2, JPN6014044835, January 2010 (2010-01-01), pages 103 - 110, ISSN: 0002925797 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018531960A (ja) * 2015-10-30 2018-11-01 ドクトル ファルク ファルマ ゲーエムベーハー 最適化高用量メサラジン含有錠剤
JP2019513800A (ja) * 2016-04-19 2019-05-30 フェリング ベスローテン フェンノートシャップ メサラジンの経口薬学的組成物
US11622938B2 (en) 2016-04-19 2023-04-11 Conaris Research Institute Ag Oral pharmaceutical compositions of nicotinamide

Also Published As

Publication number Publication date
WO2012089677A1 (en) 2012-07-05
ES2463040T3 (es) 2014-05-27
EP2621477A1 (en) 2013-08-07
HRP20140479T1 (hr) 2014-07-04
CA2822754A1 (en) 2012-07-05
RU2013125148A (ru) 2015-02-10
SA111330110B1 (ar) 2014-08-11
CN103269691A (zh) 2013-08-28
EP2468264A1 (en) 2012-06-27
DK2621477T3 (da) 2014-06-16
US20130273156A1 (en) 2013-10-17
HK1184391A1 (en) 2014-01-24
RS53363B (en) 2014-10-31
PT2621477E (pt) 2014-05-30
PL2621477T3 (pl) 2014-08-29
BR112013016461A2 (pt) 2016-09-27
EP2621477B1 (en) 2014-03-19
SI2621477T1 (sl) 2014-07-31

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