JP2014500867A5 - - Google Patents
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- JP2014500867A5 JP2014500867A5 JP2013537678A JP2013537678A JP2014500867A5 JP 2014500867 A5 JP2014500867 A5 JP 2014500867A5 JP 2013537678 A JP2013537678 A JP 2013537678A JP 2013537678 A JP2013537678 A JP 2013537678A JP 2014500867 A5 JP2014500867 A5 JP 2014500867A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- active substance
- composition
- seq
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41188410P | 2010-11-09 | 2010-11-09 | |
| US61/411,884 | 2010-11-09 | ||
| US201161527574P | 2011-08-25 | 2011-08-25 | |
| US61/527,574 | 2011-08-25 | ||
| US201161528036P | 2011-08-26 | 2011-08-26 | |
| US61/528,036 | 2011-08-26 | ||
| PCT/US2011/054967 WO2012064429A2 (en) | 2010-11-09 | 2011-10-05 | Skin permeating and cell entering (space) peptides and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014500867A JP2014500867A (ja) | 2014-01-16 |
| JP2014500867A5 true JP2014500867A5 (cg-RX-API-DMAC7.html) | 2014-11-20 |
Family
ID=46051476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013537678A Pending JP2014500867A (ja) | 2010-11-09 | 2011-10-05 | 皮膚浸透性および細胞侵入性(space)ペプチドとその使用法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8518871B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2638162B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2014500867A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20130139254A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103201386A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011326732B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2811113A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012064429A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
| EP2600901B1 (en) | 2010-08-06 | 2019-03-27 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| MX2013003681A (es) | 2010-10-01 | 2013-11-20 | Moderna Therapeutics Inc | Ácidos nucleicos manipulados y métodos de uso de los mismos. |
| US8518871B2 (en) | 2010-11-09 | 2013-08-27 | The Regents Of The University Of California | Skin permeating and cell entering (SPACE) peptides and methods of use thereof |
| WO2012135805A2 (en) | 2011-03-31 | 2012-10-04 | modeRNA Therapeutics | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| US9428535B2 (en) | 2011-10-03 | 2016-08-30 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
| SMT202200355T1 (it) | 2011-12-16 | 2022-11-18 | Modernatx Inc | Composizioni di mrna modificato |
| WO2013112488A2 (en) * | 2012-01-23 | 2013-08-01 | Kythera Biopharmaceuticals, Inc. | Dermal filling compositions and methods |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| EP2834260A4 (en) | 2012-04-02 | 2016-08-10 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES FOR THE PREPARATION OF MEMBRANE PROTEINS |
| BR112014027242A2 (pt) | 2012-05-01 | 2017-06-27 | Univ Carnegie Mellon | arranjos de microagulha carregada na ponta para inserção transdérmica |
| HK1208361A1 (en) * | 2012-05-16 | 2016-03-04 | Aadigen, Llc | Multi-target modulation for treating fibrosis and inflammatory conditions |
| KR101329411B1 (ko) | 2012-05-31 | 2013-11-14 | 주식회사 엘지생활건강 | 피부투과성 펩타이드 |
| EP2922554B1 (en) | 2012-11-26 | 2022-02-23 | ModernaTX, Inc. | Terminally modified rna |
| CN103897043A (zh) * | 2012-12-28 | 2014-07-02 | 天津药物研究院 | 一种穿膜多肽连接拉帕替尼的制备及应用 |
| US20140227174A1 (en) * | 2013-02-11 | 2014-08-14 | The Regents Of The University Of California | Skin permeating and cell entering (space) peptides and methods of use therefor |
| WO2014123543A2 (en) * | 2013-02-11 | 2014-08-14 | Convoy Therapeutics | Skin permeating and cell entering (space) peptides and methods of use therefor |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| CN105491982B (zh) * | 2013-08-12 | 2019-09-10 | 3M创新有限公司 | 用于增强透皮递送的肽 |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
| KR101602690B1 (ko) * | 2013-11-14 | 2016-03-11 | 주식회사 엘지생활건강 | 염기성 섬유모세포성장인자 융합단백질을 포함하는 피부개선용 화장료 조성물 |
| US9321821B2 (en) | 2013-11-14 | 2016-04-26 | Lg Household & Health Care Ltd. | Cosmetic composition for improving skin conditions comprising fusion protein |
| WO2016033314A1 (en) * | 2014-08-27 | 2016-03-03 | The Regents Of The University Of California | Skin penetrating peptides (spps) and methods of use therefor |
| WO2016048246A1 (en) | 2014-09-25 | 2016-03-31 | Nanyang Technological University | Targeting of melanocytes for delivering therapeutic or diagnostic agents using protein nanocages |
| WO2016071814A1 (en) | 2014-11-04 | 2016-05-12 | Università Degli Studi Di Milano | A promoter for cutaneous absorption of active ingredients having peptidic structure |
| WO2016149673A1 (en) | 2015-03-18 | 2016-09-22 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
| US10858395B2 (en) * | 2015-09-10 | 2020-12-08 | Iucf-Hyu (Industry-University Cooperation Foundation Hanyang University) | Skin-penetrating peptide and method for using same |
| WO2017043920A1 (ko) * | 2015-09-10 | 2017-03-16 | 한양대학교 산학협력단 | 피부 투과성 펩티드 및 그 이용방법 |
| WO2017048812A1 (en) * | 2015-09-15 | 2017-03-23 | The Regents Of The University Of California | Skin-penetrating peptides and compositions and methods of use thereof |
| US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
| MX2018005146A (es) | 2015-10-30 | 2018-08-23 | Bonac Corp | Composicion que contiene de manera estable molecula de acido nucleico de un solo filamento que suprime la expresion de gen tgf-b1. |
| WO2017082690A1 (ko) * | 2015-11-12 | 2017-05-18 | 주식회사 펩트론 | 미백, 피부 탄력, 주름 개선 및 상처치유 활성을 갖는 다기능성 피부투과 펩타이드 |
| WO2017120322A1 (en) | 2016-01-05 | 2017-07-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
| CN105504066A (zh) * | 2016-01-16 | 2016-04-20 | 广州市科玮生物技术有限公司 | 一种融合蛋白在化妆品中的应用 |
| EP3405151A4 (en) * | 2016-01-23 | 2019-09-11 | Ampersand Biopharmaceuticals Inc. | IMPROVED TRANSDERMAL DISTRIBUTION OF ACTIVE SUBSTANCES |
| EP3609873A1 (en) | 2017-01-17 | 2020-02-19 | Forrest, Michael, David | Therapeutic inhibitors of the reverse mode of atp synthase |
| JP2020516690A (ja) * | 2017-04-17 | 2020-06-11 | ジェイ. サンド,ブルース | 固形腫瘍の転移、色素沈着過剰および痛風を阻害する緩衝剤の非経口非全身投与 |
| KR102083978B1 (ko) * | 2017-12-18 | 2020-03-03 | 주식회사 엘지생활건강 | 혈소판유래 성장인자 a서브유닛의 융합 단백질을 포함하는 피부개선용 화장료 조성물 |
| KR102083976B1 (ko) * | 2017-12-18 | 2020-03-03 | 주식회사 엘지생활건강 | 혈관내피세포 성장인자의 융합 단백질을 포함하는 피부개선용 화장료 조성물 |
| CN118652215A (zh) | 2017-07-13 | 2024-09-17 | 迈克尔·大卫·福雷斯特 | Atp合酶反向模式的治疗性调节剂 |
| GB2566516A (en) | 2017-09-15 | 2019-03-20 | Univ Oxford Innovation Ltd | Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria |
| US20190083386A1 (en) | 2017-09-15 | 2019-03-21 | Ampersand Biopharmaceuticals, Inc. | Methods and formulations for transdermal administration of buffering agents |
| US10905738B2 (en) | 2018-07-05 | 2021-02-02 | Biozeus Desenvolvimento De Produtos Biofarmacêuticos | Synthetic peptides, prodrugs, pharmaceutical compositions and uses |
| EP3955887A1 (en) | 2019-04-19 | 2022-02-23 | Fount Bio, Inc. | Delivery and retention of active agents within the skin |
| WO2020232394A1 (en) | 2019-05-16 | 2020-11-19 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Microneedle arrays with undercut features for cutaneous and non-cutaneous drug delivery |
| WO2021113410A1 (en) * | 2019-12-02 | 2021-06-10 | Ampersand Biopharmaceuticals, Inc. | Transdermal penetrant formulations for vitamins, minerals and supplements |
| KR102301572B1 (ko) * | 2020-02-06 | 2021-09-10 | 인천대학교 산학협력단 | 신규한 핵산 분자 전달용 조성물 및 그 용도 |
| CN113943778A (zh) * | 2020-07-17 | 2022-01-18 | 通用电气医疗集团股份有限公司 | 用于核酸检测的分子探针及其制备方法和用途 |
| CN111803652B (zh) * | 2020-08-04 | 2021-09-14 | 南通康是美生物科技有限公司 | 治疗痤疮的化合物在制备治疗痤疮的药物组合物或化妆品组合物中的用途 |
| CA3206148A1 (en) | 2021-01-24 | 2022-07-28 | Michael David FORREST | Therapeutic modifiers of the reverse mode of atp synthase |
| CN114315960B (zh) * | 2021-12-31 | 2022-10-14 | 深圳市维琪医药研发有限公司 | 一种经修饰的肽及其美容组合物或药用组合物和用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH624011A5 (cg-RX-API-DMAC7.html) | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
| US5077057A (en) | 1989-04-05 | 1991-12-31 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
| US6083539A (en) | 1994-12-16 | 2000-07-04 | Sakuma Ebisu Kabushiki Kaisha | Buckwheat starch syrup, method for preparing the same, and foods containing the same |
| US6747137B1 (en) * | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US20090070897A1 (en) * | 2006-01-12 | 2009-03-12 | Goldman Barry S | Genes and uses for plant improvement |
| JP4596391B2 (ja) * | 2005-02-10 | 2010-12-08 | 国立大学法人大阪大学 | 細胞透過性ペプチド |
| WO2007035474A2 (en) | 2005-09-15 | 2007-03-29 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
| US7659252B2 (en) | 2005-09-15 | 2010-02-09 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
| JP2007143454A (ja) * | 2005-11-25 | 2007-06-14 | Toray Ind Inc | 細胞膜通過性ペプチド |
| EP1968643A2 (en) * | 2005-12-16 | 2008-09-17 | Diatos | Cell penetrating peptide conjugates for delivering of nucleic acids into a cell |
| GB0606415D0 (en) | 2006-03-31 | 2006-05-10 | Univ Southampton | Topical drug delivery |
| US20080213377A1 (en) | 2006-12-08 | 2008-09-04 | Bhatia Sangeeta N | Delivery of Nanoparticles and/or Agents to Cells |
| JP2008200011A (ja) * | 2007-02-22 | 2008-09-04 | Toray Ind Inc | 細胞内移行性ペプチド、それを含有する医薬組成物及びその使用方法 |
| CA2727971A1 (en) | 2007-08-29 | 2009-03-12 | Tufts University | Methods of making and using a cell penetrating peptide for enhanced delivery of nucleic acids, proteins, drugs, and adenovirus to tissues and cells, and compositions and kits |
| US20090233993A1 (en) * | 2008-03-06 | 2009-09-17 | Burnham Institute For Medical Research | Compositions and methods for inhibiting gsk3 activity and uses thereof |
| EP2355852A4 (en) * | 2008-09-16 | 2015-06-24 | Ge Healthcare Bio Sciences Ab | CHEMICALLY MODIFIED CELL-PENETRATING PEPTIDES FOR IMPROVED DELIVERY OF GENE MODULATING COMPOUNDS |
| US8389481B2 (en) * | 2008-11-12 | 2013-03-05 | University Of Medicine And Dentistry Of New Jersey | Glutamate-enhanced cell-penetrating peptides and methods of using same |
| CN101812439B (zh) * | 2009-02-25 | 2012-07-04 | 张舒羽 | 一种透皮结构域及其衍生的具有透皮作用的融合蛋白和其制备方法 |
| EP2421505A4 (en) * | 2009-04-22 | 2014-01-01 | Univ Texas | HYDROGELES FOR THE COMBINATORY RELEASE OF IMMUNOMODULATING BIOMOLECULES |
| WO2010129023A2 (en) | 2009-04-28 | 2010-11-11 | President And Fellows Of Harvard College | Supercharged proteins for cell penetration |
| US8518871B2 (en) * | 2010-11-09 | 2013-08-27 | The Regents Of The University Of California | Skin permeating and cell entering (SPACE) peptides and methods of use thereof |
| WO2012135805A2 (en) | 2011-03-31 | 2012-10-04 | modeRNA Therapeutics | Delivery and formulation of engineered nucleic acids |
-
2011
- 2011-10-05 US US13/253,796 patent/US8518871B2/en active Active
- 2011-10-05 EP EP11839394.1A patent/EP2638162B1/en not_active Not-in-force
- 2011-10-05 JP JP2013537678A patent/JP2014500867A/ja active Pending
- 2011-10-05 CN CN2011800532510A patent/CN103201386A/zh active Pending
- 2011-10-05 KR KR1020137008413A patent/KR20130139254A/ko not_active Withdrawn
- 2011-10-05 AU AU2011326732A patent/AU2011326732B2/en not_active Expired - Fee Related
- 2011-10-05 CA CA2811113A patent/CA2811113A1/en not_active Abandoned
- 2011-10-05 WO PCT/US2011/054967 patent/WO2012064429A2/en not_active Ceased
-
2013
- 2013-07-26 US US13/952,525 patent/US8791062B2/en active Active
-
2014
- 2014-04-25 US US14/262,453 patent/US9441014B2/en active Active
-
2016
- 2016-08-04 US US15/228,852 patent/US20170173173A1/en not_active Abandoned
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