|
GB1555654A
(en)
*
|
1977-06-25 |
1979-11-14 |
Exxon Research Engineering Co |
Agricultural burner apparatus
|
|
US4065562A
(en)
*
|
1975-12-29 |
1977-12-27 |
Nippon Shinyaku Co., Ltd. |
Method and composition for reducing blood glucose levels
|
|
NO154918C
(no)
*
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
|
GB2020278B
(en)
*
|
1978-05-03 |
1983-02-23 |
Nippon Shinyaku Co Ltd |
Moranoline dervitives
|
|
JPS568318A
(en)
|
1979-06-28 |
1981-01-28 |
Janssen Pharmaceutica Nv |
Non oral long acting composition of haloperidol and bromperidol derivative
|
|
GB8311286D0
(en)
|
1983-04-26 |
1983-06-02 |
Searle & Co |
Carboxyalkyl peptide derivatives
|
|
EP0144290A3
(de)
|
1983-12-01 |
1987-05-27 |
Ciba-Geigy Ag |
Substituierte Aethylendiaminderivate
|
|
US5041441A
(en)
*
|
1988-04-04 |
1991-08-20 |
The Regents Of The University Of Michigan |
Method of chemotherapy using 1-phenyl-2-decanoylamino-3-morpholino-1-propanol
|
|
JPH0416856A
(ja)
|
1990-05-10 |
1992-01-21 |
Canon Inc |
正帯電性非磁性トナー
|
|
US5302609A
(en)
*
|
1992-12-16 |
1994-04-12 |
The Regents Of The University Of Michigan |
Treatment of diabetic nephropathy
|
|
US5399567A
(en)
*
|
1993-05-13 |
1995-03-21 |
Monsanto Company |
Method of treating cholera
|
|
CN1128951A
(zh)
*
|
1993-08-13 |
1996-08-14 |
生化学工业株式会社 |
治疗神经元疾病的药物
|
|
ES2149350T3
(es)
*
|
1994-02-02 |
2000-11-01 |
Liposome Co Inc |
Compuestos y liposomas farmaceuticamente activos y metodos para su utilizacion.
|
|
CA2192555C
(en)
|
1994-06-10 |
2005-01-11 |
Jinichi Inokuchi |
2-acylaminopropanol compound and medicinal composition
|
|
WO2001004108A1
(en)
|
1999-07-09 |
2001-01-18 |
Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US20030073680A1
(en)
*
|
1995-09-20 |
2003-04-17 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US5916911A
(en)
*
|
1995-09-20 |
1999-06-29 |
The Regents Of The University Of Michigan |
Amino ceramide--like compounds and therapeutic methods of use
|
|
US6255336B1
(en)
*
|
1995-09-20 |
2001-07-03 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
JP3993908B2
(ja)
|
1995-12-08 |
2007-10-17 |
生化学工業株式会社 |
アミノアルコール誘導体及び該誘導体の製造方法
|
|
NO965193L
(no)
*
|
1995-12-08 |
1997-06-09 |
Seikagaku Kogyo Kk Seikagaku C |
Aminalkoholderivat og fremgangsmåte for fremstilling derav
|
|
JP4140984B2
(ja)
|
1995-12-20 |
2008-08-27 |
生化学工業株式会社 |
分化誘導作用を有する薬剤
|
|
US5972928A
(en)
|
1997-05-21 |
1999-10-26 |
Johns Hopkins University |
Methods for treatment of conditions associated with lactosylceramide
|
|
JP4036500B2
(ja)
|
1997-05-23 |
2008-01-23 |
生化学工業株式会社 |
アミノアルコール誘導体及びそれを含有する医薬
|
|
JP4176170B2
(ja)
|
1997-06-06 |
2008-11-05 |
生化学工業株式会社 |
アミノアルコール誘導体を含む医薬及び異常増殖性疾患治療薬
|
|
US6222619B1
(en)
*
|
1997-09-18 |
2001-04-24 |
University Of Utah Research Foundation |
Diagnostic device and method
|
|
US6465488B1
(en)
*
|
1997-12-11 |
2002-10-15 |
Chancellor, Masters & Scholars Of The University Of Oxford |
Inhibition of glycolipid biosynthesis
|
|
US6511979B1
(en)
*
|
1998-07-27 |
2003-01-28 |
Johns Hopkins University |
Methods for treating conditions modulated by lactosylceramide
|
|
US6610703B1
(en)
*
|
1998-12-10 |
2003-08-26 |
G.D. Searle & Co. |
Method for treatment of glycolipid storage diseases
|
|
GB0100889D0
(en)
*
|
2001-01-12 |
2001-02-21 |
Oxford Glycosciences Uk Ltd |
Compounds
|
|
JP2003521479A
(ja)
*
|
1999-07-09 |
2003-07-15 |
リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
アミノセラミド様化合物および治療目的での使用方法
|
|
EP1384719A1
(en)
|
1999-07-09 |
2004-01-28 |
The Regents of The University of Michigan |
Inhibitors of the glucosyl ceramide synthase enzyme useful for the treatment of cancers, sphingolipidosis and microbial infections
|
|
US6407064B2
(en)
|
1999-12-06 |
2002-06-18 |
Seikagaku Corporation |
Aminoalcohol derivative and medicament comprising the same
|
|
JP5009459B2
(ja)
|
1999-12-06 |
2012-08-22 |
生化学工業株式会社 |
アミノアルコール誘導体及びそれを含有する医薬
|
|
US6235737B1
(en)
*
|
2000-01-25 |
2001-05-22 |
Peter Styczynski |
Reduction of hair growth
|
|
AR028023A1
(es)
|
2000-04-19 |
2003-04-23 |
Borody Thomas J |
Una composicion farmaceutica para el tratamiento de la hiperlipidemia y el uso de dicha composicion para la preparacion de medicamentos
|
|
CA2432908A1
(en)
|
2000-12-20 |
2002-06-27 |
Bristol-Myers Squibb Pharma Company |
Diamines as modulators of chemokine receptor activity
|
|
WO2002053528A1
(en)
|
2000-12-29 |
2002-07-11 |
Wyeth |
Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines
|
|
US20040260099A1
(en)
*
|
2001-01-10 |
2004-12-23 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
EP1358172B1
(en)
|
2001-01-10 |
2009-11-18 |
The Regents of The University of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US7148251B2
(en)
*
|
2001-01-10 |
2006-12-12 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US20020198240A1
(en)
*
|
2001-01-10 |
2002-12-26 |
Shayman James A. |
Amino ceramide - like compounds and therapeutic methods of use
|
|
US6855830B2
(en)
*
|
2001-07-16 |
2005-02-15 |
Genzyme Corporation |
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors
|
|
WO2003045928A1
(en)
*
|
2001-11-26 |
2003-06-05 |
Genzyme Corporation |
Diastereoselective synthesis of udp-glucose : n-acylsphingosine glucosyltransferase inhibitors
|
|
GB0229931D0
(en)
*
|
2002-12-21 |
2003-01-29 |
Astrazeneca Ab |
Therapeutic agents
|
|
AU2002367266A1
(en)
*
|
2001-12-28 |
2003-07-24 |
Sumitomo Pharmaceuticals Company, Limited |
Disease markers for renal diseaes and utilization thereof
|
|
NZ534069A
(en)
|
2002-01-22 |
2007-03-30 |
Warner Lambert Co |
2-(Pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones to be used to treat neurodegenerative disorders, viruses and cancer
|
|
EP1336411A1
(en)
|
2002-02-14 |
2003-08-20 |
Academisch Medisch Centrum bij de Universiteit van Amsterdam |
Compositions and methods for improving enzyme replacement therapy of lysosomal storage diseases
|
|
JP2003238410A
(ja)
*
|
2002-02-21 |
2003-08-27 |
Seibutsu Yuki Kagaku Kenkyusho:Kk |
インスリン抵抗性解除剤
|
|
US6916802B2
(en)
*
|
2002-04-29 |
2005-07-12 |
Genzyme Corporation |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US20060217560A1
(en)
*
|
2002-04-29 |
2006-09-28 |
Shayman James A |
Amino ceramide-like compounds and therapeutic methods of use
|
|
ES2393331T3
(es)
|
2002-07-17 |
2012-12-20 |
Actelion Pharmaceuticals Ltd. |
Derivados de piperidintriol como inhibidores de la glucosiliceramida sintasa
|
|
CA2492649A1
(en)
|
2002-07-17 |
2004-01-22 |
Biogen Idec Ma Inc. |
Therapies for renal failure using interferon-.beta.
|
|
AU2003225670A1
(en)
|
2003-02-28 |
2004-09-28 |
Intermune, Inc. |
Interferon drug therapy for the treatment of viral diseases and liver fibrosis
|
|
GB0313678D0
(en)
*
|
2003-06-13 |
2003-07-16 |
Oxford Glycosciences Uk Ltd |
Novel compounds
|
|
EP1528056A1
(en)
*
|
2003-10-29 |
2005-05-04 |
Academisch Ziekenhuis bij de Universiteit van Amsterdam |
Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors
|
|
PL1680112T3
(pl)
|
2003-10-29 |
2011-05-31 |
Genzyme Corp |
N-(5-adamantan-1-ylometoksypentylo)deoksynojirimycyna lub dopuszczalna farmaceutycznie sól stosowane w leczeniu oporności na insulinę
|
|
US20070270350A1
(en)
|
2003-12-23 |
2007-11-22 |
Musc Foundation For Research Development |
Methods and Compositions for the Prevention and Treatment of Inflammatory Diseases or Conditions
|
|
GB0400812D0
(en)
|
2004-01-14 |
2004-02-18 |
Celltech R&D Ltd |
Novel compounds
|
|
AU2005220692A1
(en)
*
|
2004-03-16 |
2005-09-22 |
Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno |
The use of sphingolipids in the treatment and prevention of type 2 diabetes mellitus, insulin resistance and Metabolic Syndrome
|
|
EP1576894A1
(en)
*
|
2004-03-16 |
2005-09-21 |
Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO |
The use of sphingolipids in the treatment and prevention of type 2 diabetes mellitus, insulin resistance and Metabolic Syndrome
|
|
EP1743033B1
(en)
|
2004-05-07 |
2011-10-19 |
Merck Patent GmbH |
Gm3 synthase as a therapeutic target in microvascular complications of diabetes
|
|
WO2005123055A2
(en)
|
2004-06-14 |
2005-12-29 |
Musc Foundation For Research Development |
Methods for treating inflammatory disorders
|
|
AU2005277186A1
(en)
*
|
2004-08-20 |
2006-03-02 |
The Johns Hopkins University |
Methods for treatment of angiogenesis
|
|
BRPI0517701A8
(pt)
|
2004-11-10 |
2018-01-23 |
Genzyme Corp |
métodos de tratamento de diabetes mellitus
|
|
PL383715A1
(pl)
|
2005-01-26 |
2008-05-12 |
Allergan, Inc. |
Amidy kwasu 3-arylo-3-hydroksy-2-amino-propionowego, amidy kwasu 3-heteroarylo-3-hydroksy-2-amino-propionowego i ich związki pokrewne posiadające aktywność przeciwbólową i/lub pobudzającą odporność
|
|
US8389472B2
(en)
|
2005-08-19 |
2013-03-05 |
Amylin Pharmaceuticals, Llc |
Exendin-4 to treat nonalcoholic steatohepatitis and nonalcoholic fatty liver disease
|
|
ES2546181T3
(es)
|
2006-05-09 |
2015-09-21 |
Genzyme Corporation |
Métodos de tratar la enfermedad del hígado graso mediante inhibición de la síntesis de glucoesfingolípidos
|
|
WO2008011487A2
(en)
|
2006-07-19 |
2008-01-24 |
Allergan, Inc. |
L-benzyl-l-hydr0xy-2, 3-diamin0-propyl amines and 3-benzyl-3-hydroxy-2-amino-propionicacid amides for chronic pain
|
|
WO2008011478A2
(en)
|
2006-07-19 |
2008-01-24 |
Allergan, Inc. |
Methods for treating chronic pain using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds
|
|
GB0614947D0
(en)
|
2006-07-27 |
2006-09-06 |
Isis Innovation |
Epitope reduction therapy
|
|
TWI389895B
(zh)
|
2006-08-21 |
2013-03-21 |
Infinity Discovery Inc |
抑制ｂｃｌ蛋白質與結合夥伴間之交互作用的化合物及方法
|
|
CA2677485A1
(en)
|
2007-02-09 |
2008-08-14 |
Irm Llc |
Compounds and compositions as channel activating protease inhibitors
|
|
EP2594565B1
(en)
*
|
2007-05-31 |
2018-10-24 |
Genzyme Corporation |
2-acylaminopropanol-type glucosylceramide synthase inhibitors
|
|
KR101640263B1
(ko)
|
2007-10-05 |
2016-07-15 |
젠자임 코포레이션 |
세라마이드 유도체로 다낭성 신장질환을 치료하는 방법
|
|
WO2009117150A2
(en)
|
2008-03-20 |
2009-09-24 |
Genzyme Corporation |
Method of treating lupus with ceramide derivatives
|
|
JP2011529500A
(ja)
|
2008-07-28 |
2011-12-08 |
ジェンザイム コーポレーション |
虚脱性糸球体症および他の糸球体疾患の処置のためのグルコシルセラミドシンターゼ阻害
|
|
CN102271678B
(zh)
|
2008-10-03 |
2017-06-30 |
简詹姆公司 |
2‑酰胺基丙醇型葡糖神经酰胺合成酶抑制剂
|