JP2014211652A5

JP2014211652A5 -

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Publication number: JP2014211652A5
Authority: JP; Japan
Prior art keywords: ophthalmic composition; chlorobutanol; hydroxypropylmethylcellulose; salts; contact lens
Prior art date: 2014-08-01
Legal status : Granted

Application number

JP2014157318A

Other languages

English (en)

Japanese (ja)

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JP2014211652A (ja

JP5685339B2 (ja

Filing date

2014-08-01

Publication date

2014-12-25

2014-08-01 Application filed filed Critical

2014-08-01 Priority to JP2014157318A priority Critical patent/JP5685339B2/ja

2014-08-01 Priority claimed from JP2014157318A external-priority patent/JP5685339B2/ja

2014-11-13 Publication of JP2014211652A publication Critical patent/JP2014211652A/ja

2014-12-25 Publication of JP2014211652A5 publication Critical patent/JP2014211652A5/ja

2015-03-18 Application granted granted Critical

2015-03-18 Publication of JP5685339B2 publication Critical patent/JP5685339B2/ja

Status Active legal-status Critical Current

2030-12-24 Anticipated expiration legal-status Critical

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OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 claims 8
239000000203 mixture Substances 0.000 claims 8
KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 4
SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims 4
229920001287 Chondroitin sulfate Polymers 0.000 claims 4
239000000783 alginic acid Substances 0.000 claims 4
229920000615 alginic acid Polymers 0.000 claims 4
235000010443 alginic acid Nutrition 0.000 claims 4
229960001126 alginic acid Drugs 0.000 claims 4
150000004781 alginic acids Chemical class 0.000 claims 4
229960004926 chlorobutanol Drugs 0.000 claims 4
229940059329 chondroitin sulfate Drugs 0.000 claims 4
229920002674 hyaluronan Polymers 0.000 claims 4
229960003160 hyaluronic acid Drugs 0.000 claims 4
239000000017 hydrogel Substances 0.000 claims 4
239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 4
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 4
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 4
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 4
229920001296 polysiloxane Polymers 0.000 claims 4
150000003839 salts Chemical class 0.000 claims 4
235000002639 sodium chloride Nutrition 0.000 claims 4
208000035143 Bacterial infection Diseases 0.000 claims 2
208000022362 bacterial infectious disease Diseases 0.000 claims 2
239000003795 chemical substances by application Substances 0.000 claims 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
239000003112 inhibitor Substances 0.000 claims 2
238000000034 method Methods 0.000 claims 2
230000010065 bacterial adhesion Effects 0.000 claims 1
210000004877 mucosa Anatomy 0.000 claims 1
230000002265 prevention Effects 0.000 claims 1
230000003449 preventive effect Effects 0.000 claims 1
238000001179 sorption measurement Methods 0.000 claims 1

JP2014157318A 2009-12-25 2014-08-01 シリコーンハイドロゲルコンタクトレンズ用眼科組成物 Active JP5685339B2 (ja)