WO2009035033A1 - 眼科用組成物 - Google Patents

眼科用組成物 Download PDF

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Publication number
WO2009035033A1
WO2009035033A1 PCT/JP2008/066415 JP2008066415W WO2009035033A1 WO 2009035033 A1 WO2009035033 A1 WO 2009035033A1 JP 2008066415 W JP2008066415 W JP 2008066415W WO 2009035033 A1 WO2009035033 A1 WO 2009035033A1
Authority
WO
WIPO (PCT)
Prior art keywords
intended
polymer compound
group
contact lenses
base polymer
Prior art date
Application number
PCT/JP2008/066415
Other languages
English (en)
French (fr)
Inventor
Yasuko Matsumura
Kazuhiro Fukushima
Original Assignee
Rohto Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rohto Pharmaceutical Co., Ltd. filed Critical Rohto Pharmaceutical Co., Ltd.
Priority to US12/677,988 priority Critical patent/US9034843B2/en
Priority to JP2009532211A priority patent/JP5514547B2/ja
Publication of WO2009035033A1 publication Critical patent/WO2009035033A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

　本発明はコンタクトレンズ装用中の涙液層を安定化させ、目の乾きを抑制し、使用感が良く、かつ利便性に優れ、誤用の心配が無く、製造から販売に至る段階での効率性の高い眼科用組成物を提供する。より詳細には、本発明は、（Ａ）セルロース系高分子化合物、ビニル系高分子化合物、ポリエチレングリコール及びデキストランからなる群より選択される１種以上、及び（Ｂ）コンドロイチン硫酸、アルギン酸、及びそれらの塩からなる群より選択される１種以上、及び（Ｃ）非イオン性界面活性剤を含有する、コンタクトレンズ用装着点眼液を提供する。
PCT/JP2008/066415 2007-09-14 2008-09-11 眼科用組成物 WO2009035033A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/677,988 US9034843B2 (en) 2007-09-14 2008-09-11 Ophthalmic composition
JP2009532211A JP5514547B2 (ja) 2007-09-14 2008-09-11 眼科用組成物

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-239044 2007-09-14
JP2007239044 2007-09-14
JP2008-028981 2008-02-08
JP2008028981 2008-02-08

Publications (1)

Publication Number Publication Date
WO2009035033A1 true WO2009035033A1 (ja) 2009-03-19

Family

ID=40452040

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066415 WO2009035033A1 (ja) 2007-09-14 2008-09-11 眼科用組成物

Country Status (3)

Country Link
US (1) US9034843B2 (ja)
JP (6) JP5514547B2 (ja)
WO (1) WO2009035033A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009096790A (ja) * 2007-09-28 2009-05-07 Rohto Pharmaceut Co Ltd 疲れ目改善用及び／又はかすみ目改善用コンタクトレンズ装着液
JP2011006348A (ja) * 2009-06-25 2011-01-13 Lion Corp ドライアイ治療剤
JP2011093888A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 点眼剤
EP2564858A1 (en) * 2010-04-28 2013-03-06 Nihon Pharmaceuticals Co., Ltd. Composition for the treatment of aesthenopia
JP2014136684A (ja) * 2013-01-16 2014-07-28 Toray Ind Inc 液剤
WO2015029924A1 (ja) * 2013-08-26 2015-03-05 ロート製薬株式会社 眼科用組成物
JP2015107993A (ja) * 2009-12-25 2015-06-11 ロート製薬株式会社 シリコーンハイドロゲルコンタクトレンズ用眼科組成物
US9119827B2 (en) 2009-06-30 2015-09-01 Lion Corporation Ophthalmic composition
KR101858590B1 (ko) * 2013-11-28 2018-05-16 라이온 가부시키가이샤 안과용 조성물
WO2021220712A1 (ja) * 2020-04-30 2021-11-04 ロート製薬株式会社 眼科組成物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2962044B1 (fr) * 2010-04-21 2013-02-22 Horus Pharma Emulsion lacrymimetique
ES2809713T3 (es) 2012-02-22 2021-03-05 Duchesnay Inc Formulación de doxilamina y piridoxina y/o metabolitos o sales de estas
US11583496B2 (en) 2016-10-12 2023-02-21 PS Therapy Inc. Drug vehicle compositions and methods of use thereof
US11260035B2 (en) 2016-10-12 2022-03-01 Ps Therapies Ltd Topical compositions and methods of use thereof
US11766421B2 (en) 2017-09-25 2023-09-26 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease
CN109956169B (zh) * 2017-12-14 2021-05-07 四川科伦药物研究院有限公司 一种pH稳定的右旋糖酐滴眼液制品及其制备方法
JP7377795B2 (ja) * 2018-05-09 2023-11-10 ロート製薬株式会社 眼科組成物
JP2020180169A (ja) * 2019-04-23 2020-11-05 東ソー株式会社 ポリウレタンフォーム形成性組成物

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005172912A (ja) * 2003-12-08 2005-06-30 Lion Corp ソフトコンタクトレンズの装着方法及び装着液原液、並びにコンタクトレンズキット
JP2005187345A (ja) * 2003-12-24 2005-07-14 Lion Corp コンタクトレンズ装着液
JP2005343893A (ja) * 2004-05-07 2005-12-15 Rohto Pharmaceut Co Ltd 高粘度点眼剤
JP2006022087A (ja) * 2004-06-08 2006-01-26 Rohto Pharmaceut Co Ltd 眼科用清涼組成物
JP2006052160A (ja) * 2004-08-10 2006-02-23 Rohto Pharmaceut Co Ltd ドライアイ治療用眼科組成物
JP2006143590A (ja) * 2004-10-21 2006-06-08 Rohto Pharmaceut Co Ltd 粘膜適用組成物
JP2006193521A (ja) * 2004-12-17 2006-07-27 Rohto Pharmaceut Co Ltd 眼科用組成物
JP2006219484A (ja) * 2005-01-12 2006-08-24 Rohto Pharmaceut Co Ltd 眼局所適用製剤
WO2006105183A1 (en) * 2005-03-31 2006-10-05 Johnson & Johnson Vision Care, Inc. Methods of inspecting ophthalmic lenses
JP2006282586A (ja) * 2005-03-31 2006-10-19 Kobayashi Pharmaceut Co Ltd 眼科用組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3256997B2 (ja) * 1990-08-30 2002-02-18 千寿製薬株式会社 安定な水性製剤
WO1997028827A1 (fr) * 1996-02-07 1997-08-14 Rohto Pharmaceutical Co., Ltd. Composition ophtalmique possedant une viscosite adaptee
JP2001247466A (ja) 1999-12-27 2001-09-11 Santen Pharmaceut Co Ltd 涙液層の安定化システム
JP2007077053A (ja) 2005-09-13 2007-03-29 Menicon Co Ltd 眼科用液剤組成物
JP5235420B2 (ja) 2006-02-02 2013-07-10 株式会社メニコン ソフトコンタクトレンズ用点眼・装着液
US8067038B2 (en) * 2006-06-16 2011-11-29 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition for soft contact lens comprising terpenoid

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005172912A (ja) * 2003-12-08 2005-06-30 Lion Corp ソフトコンタクトレンズの装着方法及び装着液原液、並びにコンタクトレンズキット
JP2005187345A (ja) * 2003-12-24 2005-07-14 Lion Corp コンタクトレンズ装着液
JP2005343893A (ja) * 2004-05-07 2005-12-15 Rohto Pharmaceut Co Ltd 高粘度点眼剤
JP2006022087A (ja) * 2004-06-08 2006-01-26 Rohto Pharmaceut Co Ltd 眼科用清涼組成物
JP2006052160A (ja) * 2004-08-10 2006-02-23 Rohto Pharmaceut Co Ltd ドライアイ治療用眼科組成物
JP2006143590A (ja) * 2004-10-21 2006-06-08 Rohto Pharmaceut Co Ltd 粘膜適用組成物
JP2006193521A (ja) * 2004-12-17 2006-07-27 Rohto Pharmaceut Co Ltd 眼科用組成物
JP2006219484A (ja) * 2005-01-12 2006-08-24 Rohto Pharmaceut Co Ltd 眼局所適用製剤
WO2006105183A1 (en) * 2005-03-31 2006-10-05 Johnson & Johnson Vision Care, Inc. Methods of inspecting ophthalmic lenses
JP2006282586A (ja) * 2005-03-31 2006-10-19 Kobayashi Pharmaceut Co Ltd 眼科用組成物

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009096790A (ja) * 2007-09-28 2009-05-07 Rohto Pharmaceut Co Ltd 疲れ目改善用及び／又はかすみ目改善用コンタクトレンズ装着液
JP2011006348A (ja) * 2009-06-25 2011-01-13 Lion Corp ドライアイ治療剤
US9119827B2 (en) 2009-06-30 2015-09-01 Lion Corporation Ophthalmic composition
JP2011093888A (ja) * 2009-09-30 2011-05-12 Rohto Pharmaceutical Co Ltd 点眼剤
US9278062B2 (en) 2009-09-30 2016-03-08 Rohto Pharmaceutical Co., Ltd. Eye drops
JP2015107993A (ja) * 2009-12-25 2015-06-11 ロート製薬株式会社 シリコーンハイドロゲルコンタクトレンズ用眼科組成物
JP2021157197A (ja) * 2009-12-25 2021-10-07 ロート製薬株式会社 シリコーンハイドロゲルコンタクトレンズ用眼科組成物
EP2564858A1 (en) * 2010-04-28 2013-03-06 Nihon Pharmaceuticals Co., Ltd. Composition for the treatment of aesthenopia
US8663716B2 (en) 2010-04-28 2014-03-04 Nihon Pharmaceutical Co., Ltd. Composition for treatment of aesthenopia
EP2564858A4 (en) * 2010-04-28 2013-10-30 Nihon Pharmaceutical Co Ltd COMPOSITION FOR THE TREATMENT OF ASTHENOPIA
JP2014136684A (ja) * 2013-01-16 2014-07-28 Toray Ind Inc 液剤
WO2015029924A1 (ja) * 2013-08-26 2015-03-05 ロート製薬株式会社 眼科用組成物
KR101858590B1 (ko) * 2013-11-28 2018-05-16 라이온 가부시키가이샤 안과용 조성물
WO2021220712A1 (ja) * 2020-04-30 2021-11-04 ロート製薬株式会社 眼科組成物

Also Published As

Publication number Publication date
JPWO2009035033A1 (ja) 2010-12-24
JP2017206547A (ja) 2017-11-24
JP5514547B2 (ja) 2014-06-04
JP2016104758A (ja) 2016-06-09
US20100216741A1 (en) 2010-08-26
JP2020196768A (ja) 2020-12-10
JP2014098012A (ja) 2014-05-29
JP6120785B2 (ja) 2017-04-26
US9034843B2 (en) 2015-05-19
JP2019081775A (ja) 2019-05-30

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