JP2014185333A5 - - Google Patents
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- JP2014185333A5 JP2014185333A5 JP2014031227A JP2014031227A JP2014185333A5 JP 2014185333 A5 JP2014185333 A5 JP 2014185333A5 JP 2014031227 A JP2014031227 A JP 2014031227A JP 2014031227 A JP2014031227 A JP 2014031227A JP 2014185333 A5 JP2014185333 A5 JP 2014185333A5
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- general formula
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- 229920000642 polymer Polymers 0.000 claims 13
- 150000001875 compounds Chemical class 0.000 claims 12
- 239000002245 particle Substances 0.000 claims 6
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
- 239000002872 contrast media Substances 0.000 claims 2
- 239000002612 dispersion medium Substances 0.000 claims 2
- 238000003384 imaging method Methods 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 0 CC(C)(C)OC(C1O)C(C(NCCCN2N=*CC(C*)=C2)=O)O[C@@](*C(C2N(*)C2(C)OC2CO)[C@@]2O)C1O Chemical compound CC(C)(C)OC(C1O)C(C(NCCCN2N=*CC(C*)=C2)=O)O[C@@](*C(C2N(*)C2(C)OC2CO)[C@@]2O)C1O 0.000 description 3
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014031227A JP6230443B2 (ja) | 2013-02-22 | 2014-02-21 | 近赤外色素結合ヒアルロン酸誘導体およびそれを有する光イメージング用造影剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013033633 | 2013-02-22 | ||
| JP2013033633 | 2013-02-22 | ||
| JP2014031227A JP6230443B2 (ja) | 2013-02-22 | 2014-02-21 | 近赤外色素結合ヒアルロン酸誘導体およびそれを有する光イメージング用造影剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014185333A JP2014185333A (ja) | 2014-10-02 |
| JP2014185333A5 true JP2014185333A5 (enExample) | 2017-03-30 |
| JP6230443B2 JP6230443B2 (ja) | 2017-11-15 |
Family
ID=50272677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014031227A Active JP6230443B2 (ja) | 2013-02-22 | 2014-02-21 | 近赤外色素結合ヒアルロン酸誘導体およびそれを有する光イメージング用造影剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9750827B2 (enExample) |
| EP (1) | EP2958946B1 (enExample) |
| JP (1) | JP6230443B2 (enExample) |
| CN (1) | CN105008402B (enExample) |
| WO (1) | WO2014129674A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10245329B2 (en) * | 2014-09-08 | 2019-04-02 | Canon Kabushiki Kaisha | Composition having dye and conjugate of polyethyleneglycol and additive and contrast agent for photoacoustic imaging having the same |
| WO2016060277A1 (en) | 2014-10-16 | 2016-04-21 | Canon Kabushiki Kaisha | Polymer, and contrast agent for photoacoustic imaging, including the polymer |
| US10398788B2 (en) | 2014-10-24 | 2019-09-03 | Canon Kabushiki Kaisha | Polymer and contrast agent for photoacoustic imaging including the polymer |
| KR20160142199A (ko) | 2015-06-02 | 2016-12-12 | 삼성메디슨 주식회사 | 광음향 영상화를 위한 조영 조성물 및 그를 사용한 광음향 영상화하는 방법 |
| JP2017002000A (ja) * | 2015-06-12 | 2017-01-05 | キヤノン株式会社 | 化合物又はその薬学的に受容可能な塩、及び、前記化合物又はその薬学的に受容可能な塩を有する光音響イメージング用造影剤。 |
| US20180291123A1 (en) * | 2015-09-04 | 2018-10-11 | The Broad Of Regents Of The University Of Texas System | Di-functionalized hyaluronic acid derivatives and hydrogels thereof |
| JP6789636B2 (ja) | 2015-09-30 | 2020-11-25 | キヤノン株式会社 | 重合体、前記重合体を有する光音響イメージング用造影剤 |
| CN105596294B (zh) * | 2015-12-21 | 2019-05-17 | 中国科学院深圳先进技术研究院 | 一种纳米靶向载药胶束及其制备方法和一种抗癌药物及其制备方法 |
| CZ307511B6 (cs) * | 2015-12-23 | 2018-10-31 | Contipro A.S. | Fluorescenční konjugát kyseliny hyaluronové nebo jeho sůl, hydrofobizovaný konjugát, způsoby jejich přípravy a použití |
| CN108884638B (zh) * | 2016-03-22 | 2021-08-31 | 奥布专科学院 | 作为光学增白剂的多糖衍生物 |
| AU2017300629B2 (en) * | 2016-07-21 | 2019-11-07 | Boston Scientific Scimed, Inc. | Injectable compositions |
| CN106727314B (zh) * | 2017-01-13 | 2021-01-01 | 中国药科大学 | 一种基于透明质酸的光敏剂／抗肿瘤药物自组装纳米递药系统的制备与表征 |
| CN110431155A (zh) * | 2017-04-07 | 2019-11-08 | 优瑞有限公司 | 低分子量透明质酸的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6316007B1 (en) | 1995-04-04 | 2001-11-13 | Wound Healing Of Oklahoma | Combined physical and immunotherapy for cancer |
| EP0820305A2 (en) | 1995-04-04 | 1998-01-28 | Wound Healing of Oklahoma | Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant |
| US20030003048A1 (en) | 2001-04-26 | 2003-01-02 | Chun Li | Diagnostic imaging compositions, their methods of synthesis and use |
| JP2006025625A (ja) | 2004-07-12 | 2006-02-02 | Seikagaku Kogyo Co Ltd | グリコサミノグリカン分解酵素の活性測定方法 |
| US20080064954A1 (en) | 2006-08-24 | 2008-03-13 | Baylor College Of Medicine | Method of measuring propulsion in lymphatic structures |
| ITMI20061726A1 (it) | 2006-09-11 | 2008-03-12 | Fidia Farmaceutici | Derivati crosslinkati a base di acido ialuronico reticolato via click chemistry |
| JP2009155486A (ja) | 2007-12-27 | 2009-07-16 | Kikkoman Corp | 低分子化ヒアルロン酸とその製造法 |
| EP2493458A2 (en) | 2009-10-30 | 2012-09-05 | The Ohio State University | Multi-functional biodegradable particles for selectable targeting, imaging, and therapeutic delivery and use thereof for treating ocular disorders |
| HUE041616T2 (hu) | 2010-01-28 | 2019-05-28 | National Univ Corporation Mie Univ | Indocianin vegyület, szintézisének eljárása, tisztítási eljárása, indocianin vegyületet alkalmazó diagnosztikai készítmény, és készülék in vivo kinetika mérésére és készülék keringés megjelenítésére a diagnosztikai készítmény alkalmazásával |
| JP2014129318A (ja) | 2012-02-23 | 2014-07-10 | Canon Inc | インドシアニングリーン含有粒子、およびそれを有する光音響イメージング用造影剤 |
| JP6195339B2 (ja) | 2012-07-10 | 2017-09-13 | キヤノン株式会社 | 粒子及び前記粒子を有する光音響用造影剤 |
| WO2014013732A1 (en) | 2012-07-20 | 2014-01-23 | Canon Kabushiki Kaisha | Compound and photoacoustic imaging contrast medium containing the compound |
| WO2014013729A1 (en) | 2012-07-20 | 2014-01-23 | Canon Kabushiki Kaisha | Contrast agent for photoacoustic imaging |
| CN104470546B (zh) | 2012-07-20 | 2018-02-27 | 佳能株式会社 | 化合物和含有所述化合物的光声成像造影剂 |
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2014
- 2014-02-21 EP EP14709763.8A patent/EP2958946B1/en active Active
- 2014-02-21 CN CN201480009911.9A patent/CN105008402B/zh active Active
- 2014-02-21 WO PCT/JP2014/054990 patent/WO2014129674A1/en not_active Ceased
- 2014-02-21 US US14/767,362 patent/US9750827B2/en active Active
- 2014-02-21 JP JP2014031227A patent/JP6230443B2/ja active Active