PL2530093T3 - Związek indocyjaninowy, jego metoda syntezy, metoda jego oczyszczania, kompozycja diagnostyczna wykorzystująca związek indocyjaninowy oraz urządzenie do pomiaru biokinetyki in vivo i urządzenie do wizualizacji krążenia wykorzystujące kompozycję diagnostyczną - Google Patents
Związek indocyjaninowy, jego metoda syntezy, metoda jego oczyszczania, kompozycja diagnostyczna wykorzystująca związek indocyjaninowy oraz urządzenie do pomiaru biokinetyki in vivo i urządzenie do wizualizacji krążenia wykorzystujące kompozycję diagnostycznąInfo
- Publication number
- PL2530093T3 PL2530093T3 PL11736813T PL11736813T PL2530093T3 PL 2530093 T3 PL2530093 T3 PL 2530093T3 PL 11736813 T PL11736813 T PL 11736813T PL 11736813 T PL11736813 T PL 11736813T PL 2530093 T3 PL2530093 T3 PL 2530093T3
- Authority
- PL
- Poland
- Prior art keywords
- diagnostic composition
- indocyanine compound
- measuring
- synthesis method
- vivo kinetics
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 238000001727 in vivo Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 238000001308 synthesis method Methods 0.000 title 1
Classifications
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
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- A—HUMAN NECESSITIES
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- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
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- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
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- A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
- A61B5/201—Assessing renal or kidney functions
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- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
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- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
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- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
- C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
- C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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- C09B68/00—Organic pigments surface-modified by grafting, e.g. by establishing covalent or complex bonds, in order to improve the pigment properties, e.g. dispersibility or rheology
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B68/00—Organic pigments surface-modified by grafting, e.g. by establishing covalent or complex bonds, in order to improve the pigment properties, e.g. dispersibility or rheology
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- A61K49/0017—Fluorescence in vivo
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B68/00—Organic pigments surface-modified by grafting, e.g. by establishing covalent or complex bonds, in order to improve the pigment properties, e.g. dispersibility or rheology
- C09B68/40—Organic pigments surface-modified by grafting, e.g. by establishing covalent or complex bonds, in order to improve the pigment properties, e.g. dispersibility or rheology characterised by the chemical nature of the attached groups
- C09B68/41—Polymers attached to the pigment surface
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- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
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- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Polymers & Plastics (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Nanotechnology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Signal Processing (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Artificial Intelligence (AREA)
- Anesthesiology (AREA)
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- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010017255 | 2010-01-28 | ||
JP2010132923 | 2010-06-10 | ||
PCT/JP2011/000489 WO2011093098A1 (ja) | 2010-01-28 | 2011-01-28 | 新規インドシアニン化合物、その合成法及びその精製法、そのインドシアニン化合物を用いた診断用組成物、その診断用組成物を使用する生体内動態測定装置、並びに循環可視化装置 |
EP11736813.4A EP2530093B1 (en) | 2010-01-28 | 2011-01-28 | Indocyanine compound, synthesis method thereof, purification method thereof, diagnostic composition using indocyanine compound, and device for measuring in vivo kinetics and device for visualizing circulation using diagnostic composition |
Publications (1)
Publication Number | Publication Date |
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PL2530093T3 true PL2530093T3 (pl) | 2019-06-28 |
Family
ID=44319092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL11736813T PL2530093T3 (pl) | 2010-01-28 | 2011-01-28 | Związek indocyjaninowy, jego metoda syntezy, metoda jego oczyszczania, kompozycja diagnostyczna wykorzystująca związek indocyjaninowy oraz urządzenie do pomiaru biokinetyki in vivo i urządzenie do wizualizacji krążenia wykorzystujące kompozycję diagnostyczną |
Country Status (10)
Country | Link |
---|---|
US (5) | US9056131B2 (pl) |
EP (1) | EP2530093B1 (pl) |
JP (1) | JP5721234B2 (pl) |
CN (2) | CN102770460A (pl) |
DK (1) | DK2530093T3 (pl) |
ES (1) | ES2708697T3 (pl) |
HU (1) | HUE041616T2 (pl) |
PL (1) | PL2530093T3 (pl) |
PT (1) | PT2530093T (pl) |
WO (1) | WO2011093098A1 (pl) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2530093T (pt) * | 2010-01-28 | 2018-12-28 | Univ Nagoya Nat Univ Corp | Composto de indocianina, método de síntese do mesmo, método de purificação do mesmo, composição de diagnóstico utilizando o composto de indocianina, e dispositivo para medição da cinética in vivo e dispositivo para visualização da circulação utilizando a composição de diagnóstico |
JP6029050B2 (ja) * | 2012-06-22 | 2016-11-24 | 国立大学法人三重大学 | 血管透過性亢進評価剤、血管透過性亢進評価方法、および血管透過性亢進評価装置 |
CN105008402B (zh) * | 2013-02-22 | 2018-09-18 | 佳能株式会社 | 近红外色素结合的透明质酸衍生物和包括其的光学成像用造影剂 |
JP6464534B2 (ja) * | 2014-08-02 | 2019-02-06 | エルジー・ケム・リミテッド | 染料複合体、光変換フィルムおよびそれを含む電子素子 |
US10245329B2 (en) * | 2014-09-08 | 2019-04-02 | Canon Kabushiki Kaisha | Composition having dye and conjugate of polyethyleneglycol and additive and contrast agent for photoacoustic imaging having the same |
GB2568550B (en) * | 2017-11-21 | 2021-06-30 | Univ Cape Town | Method of synthesising 6-deoxy-6-amino-ß-d-glucopyranoside-containing polymers |
US20210230427A1 (en) * | 2018-05-09 | 2021-07-29 | Board Of Trustees Of Michigan State University | Near-infrared harvesting transparent luminescent solar concentrators with engineered stokes shift |
WO2020159448A1 (en) * | 2019-02-01 | 2020-08-06 | Nanyang Technological University | Molecular renal probes for detecting acute kidney injury |
CN111134622B (zh) * | 2019-05-24 | 2021-03-02 | 四川大学华西医院 | 一种无创检测体内吲哚菁绿含量的装置 |
WO2021105888A1 (en) | 2019-11-27 | 2021-06-03 | Astellas Pharma, Inc. | Crystal of indocyanine compound |
CN112891557A (zh) * | 2021-02-03 | 2021-06-04 | 柯阳 | 一种ICG-β-环糊精载药系统及其制备方法和应用 |
KR20230159591A (ko) | 2021-03-24 | 2023-11-21 | 아스테라스 세이야쿠 가부시키가이샤 | 암 조영용 조성물 |
WO2023007404A1 (en) | 2021-07-28 | 2023-02-02 | Astellas Pharma Inc. | Pudexacianinium for nirf imaging |
WO2023095887A1 (ja) * | 2021-11-26 | 2023-06-01 | アステラス製薬株式会社 | インドシアニン化合物含有固形医薬組成物 |
WO2024059825A1 (en) | 2022-09-16 | 2024-03-21 | Stryker Corporation | Systems and methods for quantifying user observed visualization of fluorescence imaging agents |
WO2024084287A1 (en) | 2022-10-21 | 2024-04-25 | Astellas Pharma Inc. | Composition for near infrared lymphatic imaging and uses and dosages therefor |
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IT1276833B1 (it) * | 1995-10-09 | 1997-11-03 | Sorin Biomedica Cardio Spa | Coloranti fluorescenti della famiglia della solfo benz e indocianina |
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JP2000095758A (ja) | 1998-09-18 | 2000-04-04 | Schering Ag | 近赤外蛍光造影剤および蛍光造影方法 |
JP4041613B2 (ja) * | 1999-03-12 | 2008-01-30 | 富士フイルム株式会社 | 画像形成材料 |
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AU2006340061A1 (en) | 2006-02-24 | 2007-09-20 | Mallinckrodt Llc | Process for using optical agents |
US20080154102A1 (en) | 2006-07-03 | 2008-06-26 | Frangioni John V | Intraoperative imaging methods |
WO2008016139A1 (fr) | 2006-08-04 | 2008-02-07 | Osaka University | Dérivé fluorescent d'oléamide et ses utilisations |
US8343463B2 (en) * | 2009-07-31 | 2013-01-01 | Numira Biosciences Inc. | Optical imaging agent |
PT2530093T (pt) | 2010-01-28 | 2018-12-28 | Univ Nagoya Nat Univ Corp | Composto de indocianina, método de síntese do mesmo, método de purificação do mesmo, composição de diagnóstico utilizando o composto de indocianina, e dispositivo para medição da cinética in vivo e dispositivo para visualização da circulação utilizando a composição de diagnóstico |
JP5817073B2 (ja) | 2010-01-28 | 2015-11-18 | 国立大学法人三重大学 | 新規インドシアニン化合物を用いた診断用組成物及び分析方法 |
-
2011
- 2011-01-28 PT PT11736813T patent/PT2530093T/pt unknown
- 2011-01-28 CN CN201180006735XA patent/CN102770460A/zh active Pending
- 2011-01-28 WO PCT/JP2011/000489 patent/WO2011093098A1/ja active Application Filing
- 2011-01-28 EP EP11736813.4A patent/EP2530093B1/en active Active
- 2011-01-28 CN CN201710146571.XA patent/CN106977628B/zh active Active
- 2011-01-28 PL PL11736813T patent/PL2530093T3/pl unknown
- 2011-01-28 ES ES11736813T patent/ES2708697T3/es active Active
- 2011-01-28 US US13/575,810 patent/US9056131B2/en active Active
- 2011-01-28 HU HUE11736813A patent/HUE041616T2/hu unknown
- 2011-01-28 JP JP2011551776A patent/JP5721234B2/ja active Active
- 2011-01-28 DK DK11736813.4T patent/DK2530093T3/en active
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2015
- 2015-02-06 US US14/616,117 patent/US9844606B2/en active Active
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2017
- 2017-02-21 US US15/438,047 patent/US10086090B2/en active Active
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2018
- 2018-08-13 US US16/101,544 patent/US10350310B2/en active Active
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2019
- 2019-05-10 US US16/408,495 patent/US11344632B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
HUE041616T2 (hu) | 2019-05-28 |
PT2530093T (pt) | 2018-12-28 |
CN106977628A (zh) | 2017-07-25 |
DK2530093T3 (en) | 2019-01-28 |
US9844606B2 (en) | 2017-12-19 |
EP2530093B1 (en) | 2018-11-21 |
US11344632B2 (en) | 2022-05-31 |
US20150152267A1 (en) | 2015-06-04 |
US20180353626A1 (en) | 2018-12-13 |
JP5721234B2 (ja) | 2015-05-20 |
CN102770460A (zh) | 2012-11-07 |
US20120302881A1 (en) | 2012-11-29 |
JPWO2011093098A1 (ja) | 2013-05-30 |
ES2708697T3 (es) | 2019-04-10 |
US20170157273A1 (en) | 2017-06-08 |
EP2530093A4 (en) | 2016-07-06 |
US9056131B2 (en) | 2015-06-16 |
EP2530093A1 (en) | 2012-12-05 |
US10086090B2 (en) | 2018-10-02 |
US20190262477A1 (en) | 2019-08-29 |
US10350310B2 (en) | 2019-07-16 |
CN106977628B (zh) | 2021-04-13 |
WO2011093098A1 (ja) | 2011-08-04 |
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