JP2014015489A5 - - Google Patents
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- Publication number
- JP2014015489A5 JP2014015489A5 JP2013225889A JP2013225889A JP2014015489A5 JP 2014015489 A5 JP2014015489 A5 JP 2014015489A5 JP 2013225889 A JP2013225889 A JP 2013225889A JP 2013225889 A JP2013225889 A JP 2013225889A JP 2014015489 A5 JP2014015489 A5 JP 2014015489A5
- Authority
- JP
- Japan
- Prior art keywords
- ylthio
- dichlorobenzyl
- thiazol
- carboxymethyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013078 crystal Substances 0.000 claims 5
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 238000000634 powder X-ray diffraction Methods 0.000 claims 3
- 125000006512 3,4-dichlorobenzyl group Chemical group [H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])* 0.000 claims 2
- 238000000113 differential scanning calorimetry Methods 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 125000004312 morpholin-2-yl group Chemical group [H]N1C([H])([H])C([H])([H])OC([H])(*)C1([H])[H] 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000001228 spectrum Methods 0.000 claims 2
- QBXNXHODSIQDRT-AWEZNQCLSA-N 2-[2-[2-[[(2s)-4-[(3,4-dichlorophenyl)methyl]morpholin-2-yl]methylamino]-2-oxoethyl]sulfanyl-1,3-thiazol-4-yl]acetic acid Chemical compound OC(=O)CC1=CSC(SCC(=O)NC[C@@H]2OCCN(CC=3C=C(Cl)C(Cl)=CC=3)C2)=N1 QBXNXHODSIQDRT-AWEZNQCLSA-N 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010744 Conjunctivitis allergic Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000003926 Myelitis Diseases 0.000 claims 1
- 206010039085 Rhinitis allergic Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 208000002205 allergic conjunctivitis Diseases 0.000 claims 1
- 230000000172 allergic effect Effects 0.000 claims 1
- 201000010105 allergic rhinitis Diseases 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 208000024998 atopic conjunctivitis Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000001938 differential scanning calorimetry curve Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 201000009890 sinusitis Diseases 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013225889A JP2014015489A (ja) | 2006-07-11 | 2013-10-30 | モルホリン化合物の塩 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006190437 | 2006-07-11 | ||
| JP2006190437 | 2006-07-11 | ||
| JP2013225889A JP2014015489A (ja) | 2006-07-11 | 2013-10-30 | モルホリン化合物の塩 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524814A Division JP5501615B2 (ja) | 2006-07-11 | 2007-07-11 | モルホリン化合物の塩 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014015489A JP2014015489A (ja) | 2014-01-30 |
| JP2014015489A5 true JP2014015489A5 (OSRAM) | 2014-03-20 |
Family
ID=38923247
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524814A Expired - Fee Related JP5501615B2 (ja) | 2006-07-11 | 2007-07-11 | モルホリン化合物の塩 |
| JP2013225889A Pending JP2014015489A (ja) | 2006-07-11 | 2013-10-30 | モルホリン化合物の塩 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008524814A Expired - Fee Related JP5501615B2 (ja) | 2006-07-11 | 2007-07-11 | モルホリン化合物の塩 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8030303B2 (OSRAM) |
| EP (1) | EP2042499B1 (OSRAM) |
| JP (2) | JP5501615B2 (OSRAM) |
| ES (1) | ES2687756T3 (OSRAM) |
| TW (1) | TWI399375B (OSRAM) |
| WO (1) | WO2008007691A1 (OSRAM) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2042499B1 (en) * | 2006-07-11 | 2018-06-27 | Mitsubishi Tanabe Pharma Corporation | Salt of a morpholine compound |
| JP6382816B2 (ja) * | 2013-07-24 | 2018-08-29 | 田辺三菱製薬株式会社 | 眼科疾患治療剤 |
| WO2020203822A1 (ja) * | 2019-03-29 | 2020-10-08 | 千寿製薬株式会社 | 血管新生を伴う網膜疾患の治療又は予防のための併用医薬 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005097120A (ja) | 2000-10-06 | 2005-04-14 | Mochida Pharmaceut Co Ltd | ４−ヒドロキシピペリジン誘導体の非潮解性塩 |
| ATE388947T1 (de) * | 2002-12-23 | 2008-03-15 | Lundbeck & Co As H | Escitalopramhydrobromid und ein verfahren zu dessen herstellung |
| WO2006028284A1 (ja) * | 2004-09-08 | 2006-03-16 | Mitsubishi Pharma Corporation | モルホリン化合物 |
| KR101137880B1 (ko) | 2004-12-31 | 2012-04-20 | 엘지디스플레이 주식회사 | 쉬프트 레지스터 및 그 구동 방법 |
| EP2042499B1 (en) * | 2006-07-11 | 2018-06-27 | Mitsubishi Tanabe Pharma Corporation | Salt of a morpholine compound |
-
2007
- 2007-07-11 EP EP07790605.5A patent/EP2042499B1/en not_active Not-in-force
- 2007-07-11 TW TW096125165A patent/TWI399375B/zh not_active IP Right Cessation
- 2007-07-11 WO PCT/JP2007/063801 patent/WO2008007691A1/ja not_active Ceased
- 2007-07-11 US US12/309,196 patent/US8030303B2/en not_active Expired - Fee Related
- 2007-07-11 JP JP2008524814A patent/JP5501615B2/ja not_active Expired - Fee Related
- 2007-07-11 ES ES07790605.5T patent/ES2687756T3/es active Active
-
2013
- 2013-10-30 JP JP2013225889A patent/JP2014015489A/ja active Pending
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