JP2016539985A5 - - Google Patents
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- JP2016539985A5 JP2016539985A5 JP2016537999A JP2016537999A JP2016539985A5 JP 2016539985 A5 JP2016539985 A5 JP 2016539985A5 JP 2016537999 A JP2016537999 A JP 2016537999A JP 2016537999 A JP2016537999 A JP 2016537999A JP 2016539985 A5 JP2016539985 A5 JP 2016539985A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- disease
- compound according
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361914085P | 2013-12-10 | 2013-12-10 | |
| US61/914,085 | 2013-12-10 | ||
| US201461979619P | 2014-04-15 | 2014-04-15 | |
| US61/979,619 | 2014-04-15 | ||
| PCT/US2014/069487 WO2015089149A1 (en) | 2013-12-10 | 2014-12-10 | Trifluoromethyl pyrazolyl guanidine f1fo-atpase inhibitors and therapeutic uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539985A JP2016539985A (ja) | 2016-12-22 |
| JP2016539985A5 true JP2016539985A5 (OSRAM) | 2018-01-25 |
| JP6486364B2 JP6486364B2 (ja) | 2019-03-20 |
Family
ID=53371791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537999A Expired - Fee Related JP6486364B2 (ja) | 2013-12-10 | 2014-12-10 | トリフルオロメチルピラゾリルグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤及びその治療用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9266839B2 (OSRAM) |
| EP (1) | EP3080089B1 (OSRAM) |
| JP (1) | JP6486364B2 (OSRAM) |
| CN (1) | CN105899489A (OSRAM) |
| AU (1) | AU2014363904B2 (OSRAM) |
| BR (1) | BR112016013116A8 (OSRAM) |
| CA (1) | CA2931851A1 (OSRAM) |
| IL (1) | IL245930A0 (OSRAM) |
| MX (1) | MX2016007445A (OSRAM) |
| WO (1) | WO2015089149A1 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2591156T3 (es) | 2010-12-08 | 2016-11-25 | Lycera Corporation | Inhibidores de F1F0-ATPasas de tipo piridonil guanidina y sus usos terapéuticos |
| PL2648511T3 (pl) | 2010-12-08 | 2017-12-29 | Lycera Corporation | Pirazoliloguanidynowe inhibitory F1F0-ATPaz i ich zastosowania terapeutyczne |
| EP2866893A4 (en) | 2012-06-08 | 2015-12-23 | Lycera Corp | HETEROCYCLIC GUANIDINE F1FO ATPASE INHIBITORS |
| US9920012B2 (en) | 2012-06-08 | 2018-03-20 | Lycera Corporation | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
| WO2013185046A1 (en) | 2012-06-08 | 2013-12-12 | Lycera Corporation | Saturated acyl guanid1ne for inhibition of f1f0-atpase |
| JP6486364B2 (ja) | 2013-12-10 | 2019-03-20 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | トリフルオロメチルピラゾリルグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤及びその治療用途 |
| JP2016539993A (ja) | 2013-12-10 | 2016-12-22 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | Ｎ−置換ピラゾリルグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤及びその治療用途 |
| US9815791B2 (en) | 2013-12-10 | 2017-11-14 | Lycera Corporation | Alkylpyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
| CN116570589B (zh) * | 2023-05-30 | 2025-02-11 | 南阳理工学院 | 化合物Parimifasor在制备抗肿瘤药物中的应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4977189A (en) * | 1986-05-07 | 1990-12-11 | American Cyanamid Company | Substituted guanidinedicarbonyl derivatives |
| JPH07188197A (ja) | 1993-11-17 | 1995-07-25 | Fujisawa Pharmaceut Co Ltd | オキサゾール誘導体 |
| DE4344550A1 (de) | 1993-12-24 | 1995-06-29 | Hoechst Ag | Substituierte 1-Oxo-1,2-dihydro-isochinolinoyl- und 1,1-Dioxo-2H-1,2-benzothiazinoylguanidine, Verfahrenzu ihrer Herstellung, ihre Verwendung als Medikamentt oder Diagnostikum sowie sie enthaltendes Medikamen |
| US7041702B1 (en) | 1997-10-21 | 2006-05-09 | Scion Pharmaceuticals, Inc. | Pharmaceutically active compounds and methods of use |
| EP1156803A4 (en) | 1999-02-09 | 2004-03-17 | Bristol Myers Squibb Co | FXA LACTAM INHIBITORS AND METHOD |
| US7276348B2 (en) | 1999-04-30 | 2007-10-02 | Regents Of The University Of Michigan | Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof |
| KR20020012310A (ko) | 1999-07-15 | 2002-02-15 | 다께우찌 마사야쓰 | 복소 방향환 화합물 |
| CA2413245A1 (en) | 2000-06-30 | 2002-01-10 | Bristol-Myers Squibb Pharma Company | N-ureidoheterocycloaklyl-piperidines as modulators of chemokine receptor activity |
| WO2003050261A2 (en) | 2001-12-10 | 2003-06-19 | Bristol-Myers Squibb Company | (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial f1f0 atp hydrolase |
| GB0208224D0 (en) | 2002-04-10 | 2002-05-22 | Celltech R&D Ltd | Chemical compounds |
| AU2003276648A1 (en) | 2002-06-17 | 2003-12-31 | Bristol-Myers Squibb Company | Benzodiazepine inhibitors of mitochondial f¿1?f¿0? atp hydrolase and methods of inhibiting f¿1?f¿0? atp hydrolase |
| AU2003295402A1 (en) | 2002-11-06 | 2004-06-03 | Bristol-Myers Squibb Company | Acyl guanidine compounds and use thereof |
| EP1590338B1 (en) | 2002-12-04 | 2009-08-26 | Ore Pharmaceuticals Inc. | Modulators of melanocortin receptor |
| DE102004008141A1 (de) | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| US20090275099A1 (en) | 2004-04-27 | 2009-11-05 | Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20050272723A1 (en) | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| JP4990766B2 (ja) | 2004-07-01 | 2012-08-01 | シンタ ファーマシューティカルズ コーポレーション | 二置換型ヘテロアリール化合物 |
| WO2007146167A1 (en) | 2006-06-09 | 2007-12-21 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| WO2009036175A2 (en) | 2007-09-14 | 2009-03-19 | The Regents Of The University Of Michigan | F1f0-atpase inhibitors and related methods |
| AU2008345225A1 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| KR100982661B1 (ko) | 2008-04-22 | 2010-09-17 | 전남대학교산학협력단 | 플라스멥신 ⅱ 활성을 저해하는 화합물을 유효성분으로함유하는 말라리아 예방 및 치료를 위한 약학 조성물 및이를 이용한 말라리아 치료방법 |
| EP2352724B1 (en) | 2008-09-11 | 2015-04-22 | The Regents of the University of Michigan | Aryl guanidine f1f0-atpase inhibitors and their medical use |
| US9169199B2 (en) | 2010-12-08 | 2015-10-27 | Lycera Corporation | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
| ES2591156T3 (es) | 2010-12-08 | 2016-11-25 | Lycera Corporation | Inhibidores de F1F0-ATPasas de tipo piridonil guanidina y sus usos terapéuticos |
| CA2820035A1 (en) * | 2010-12-08 | 2012-06-14 | Lycera Corporation | Cycloalkyl guanidine f1f0-atpase inhibitors and therapeutic uses thereof |
| PL2648511T3 (pl) | 2010-12-08 | 2017-12-29 | Lycera Corporation | Pirazoliloguanidynowe inhibitory F1F0-ATPaz i ich zastosowania terapeutyczne |
| WO2013185046A1 (en) | 2012-06-08 | 2013-12-12 | Lycera Corporation | Saturated acyl guanid1ne for inhibition of f1f0-atpase |
| US9920012B2 (en) | 2012-06-08 | 2018-03-20 | Lycera Corporation | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
| EP2866893A4 (en) | 2012-06-08 | 2015-12-23 | Lycera Corp | HETEROCYCLIC GUANIDINE F1FO ATPASE INHIBITORS |
| JP2016539993A (ja) | 2013-12-10 | 2016-12-22 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | Ｎ−置換ピラゾリルグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤及びその治療用途 |
| JP6486364B2 (ja) | 2013-12-10 | 2019-03-20 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | トリフルオロメチルピラゾリルグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤及びその治療用途 |
| US9815791B2 (en) | 2013-12-10 | 2017-11-14 | Lycera Corporation | Alkylpyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
-
2014
- 2014-12-10 JP JP2016537999A patent/JP6486364B2/ja not_active Expired - Fee Related
- 2014-12-10 AU AU2014363904A patent/AU2014363904B2/en not_active Ceased
- 2014-12-10 EP EP14869792.3A patent/EP3080089B1/en not_active Not-in-force
- 2014-12-10 MX MX2016007445A patent/MX2016007445A/es unknown
- 2014-12-10 US US14/565,463 patent/US9266839B2/en not_active Expired - Fee Related
- 2014-12-10 CN CN201480072404.XA patent/CN105899489A/zh active Pending
- 2014-12-10 CA CA2931851A patent/CA2931851A1/en not_active Abandoned
- 2014-12-10 WO PCT/US2014/069487 patent/WO2015089149A1/en not_active Ceased
- 2014-12-10 BR BR112016013116A patent/BR112016013116A8/pt not_active Application Discontinuation
-
2016
- 2016-02-04 US US15/015,403 patent/US9707211B2/en not_active Expired - Fee Related
- 2016-05-30 IL IL245930A patent/IL245930A0/en unknown
-
2017
- 2017-06-23 US US15/631,380 patent/US10085972B2/en not_active Expired - Fee Related
-
2018
- 2018-09-06 US US16/123,051 patent/US20190175556A1/en not_active Abandoned
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