JP2013544850A5 - - Google Patents
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- Publication number
- JP2013544850A5 JP2013544850A5 JP2013542235A JP2013542235A JP2013544850A5 JP 2013544850 A5 JP2013544850 A5 JP 2013544850A5 JP 2013542235 A JP2013542235 A JP 2013542235A JP 2013542235 A JP2013542235 A JP 2013542235A JP 2013544850 A5 JP2013544850 A5 JP 2013544850A5
- Authority
- JP
- Japan
- Prior art keywords
- azabicyclo
- dichlorophenyl
- hexane
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41976910P | 2010-12-03 | 2010-12-03 | |
| US61/419,769 | 2010-12-03 | ||
| PCT/US2011/063193 WO2012075473A1 (en) | 2010-12-03 | 2011-12-02 | Preparation and use of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane in the treatment of conditions affected by monoamine neurotransmitters |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017000485A Division JP2017114861A (ja) | 2010-12-03 | 2017-01-05 | モノアミン神経伝達物質によって影響を受ける病態の処置における（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］ヘキサンの調製および使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013544850A JP2013544850A (ja) | 2013-12-19 |
| JP2013544850A5 true JP2013544850A5 (enExample) | 2015-01-29 |
Family
ID=46172308
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542235A Pending JP2013544850A (ja) | 2010-12-03 | 2011-12-02 | モノアミン神経伝達物質によって影響を受ける病態の処置における（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］ヘキサンの調製および使用 |
| JP2017000485A Pending JP2017114861A (ja) | 2010-12-03 | 2017-01-05 | モノアミン神経伝達物質によって影響を受ける病態の処置における（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］ヘキサンの調製および使用 |
| JP2018177184A Pending JP2019031502A (ja) | 2010-12-03 | 2018-09-21 | モノアミン神経伝達物質によって影響を受ける病態の処置における（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］ヘキサンの調製および使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017000485A Pending JP2017114861A (ja) | 2010-12-03 | 2017-01-05 | モノアミン神経伝達物質によって影響を受ける病態の処置における（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］ヘキサンの調製および使用 |
| JP2018177184A Pending JP2019031502A (ja) | 2010-12-03 | 2018-09-21 | モノアミン神経伝達物質によって影響を受ける病態の処置における（＋）−１−（３，４−ジクロロフェニル）−３−アザビシクロ［３．１．０］ヘキサンの調製および使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US20120258994A1 (enExample) |
| EP (1) | EP2646019A4 (enExample) |
| JP (3) | JP2013544850A (enExample) |
| KR (1) | KR20140053822A (enExample) |
| AU (1) | AU2011336318A1 (enExample) |
| BR (1) | BR112013013572A2 (enExample) |
| CA (1) | CA2834713A1 (enExample) |
| WO (1) | WO2012075473A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010521496A (ja) | 2007-03-14 | 2010-06-24 | ノップ ニューロサイエンシーズ、インク． | キラル精製置換ベンゾチアゾールジアミンの合成 |
| CA2734491A1 (en) | 2008-08-19 | 2010-02-25 | Knopp Neurosciences, Inc. | Compositions and methods of using (r)-pramipexole |
| US20140206740A1 (en) | 2011-07-30 | 2014-07-24 | Neurovance, Inc. | Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters |
| US20140228421A1 (en) * | 2011-09-07 | 2014-08-14 | Anthony McKinney | Methods For Inhibiting Native And Promiscuous Uptake Of Monoamine Neurotransmitters |
| US20130123238A1 (en) * | 2011-11-16 | 2013-05-16 | Anthony Alexander McKINNEY | Use of (+)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane to treat addictive and alcohol-related disorders |
| WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| WO2014113844A1 (en) * | 2013-01-28 | 2014-07-31 | Brc Operations Pty Limited | White matter diffusion tensor imaging test to predict treatment outcomes in medical treatment |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| WO2014134569A1 (en) * | 2013-02-28 | 2014-09-04 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| WO2014182279A1 (en) * | 2013-05-07 | 2014-11-13 | Euthymics Bioscience, Inc. | Use of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane to treat addictive and alcohol-related disorders |
| US9566264B2 (en) | 2013-07-01 | 2017-02-14 | Euthymics Bioscience, Inc. | Combinations and methods |
| CN105764507B (zh) | 2013-07-12 | 2019-07-19 | 诺普生物科学有限责任公司 | 治疗升高的嗜酸性粒细胞和/或嗜碱性粒细胞的水平 |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| WO2015023786A1 (en) | 2013-08-13 | 2015-02-19 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
| EP3033081B1 (en) | 2013-08-13 | 2021-05-12 | Knopp Biosciences LLC | Compositions and methods for treating chronic urticaria |
| EP3524247A1 (en) * | 2013-11-11 | 2019-08-14 | Impax Laboratories, Inc. | Rapidly disintegrating formulations and methods of use |
| CN104683094B (zh) * | 2013-11-29 | 2018-10-26 | 上海华虹集成电路有限责任公司 | 用于rsa密码的蒙哥马利阶梯算法 |
| KR20160101012A (ko) * | 2013-12-09 | 2016-08-24 | 뉴로반스, 인크. | 신규 조성물 |
| WO2018002926A1 (en) | 2016-06-28 | 2018-01-04 | Seach Sarid Ltd. | A dosage form for vaporization and smoking |
| CN112118886B (zh) * | 2018-05-23 | 2022-08-23 | 上海汉都医药科技有限公司 | 活性药物成分的控释系统及其制备方法 |
| US11911513B2 (en) | 2018-05-23 | 2024-02-27 | Shanghai Wd Pharmaceutical Co., Ltd | Controlled-release system of active pharmaceutical ingredient and preparation method therefor |
| WO2020087031A1 (en) | 2018-10-26 | 2020-04-30 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| WO2020142545A1 (en) | 2018-12-31 | 2020-07-09 | Ethismos Research, Inc. | Novel methods |
| US11554154B2 (en) * | 2020-07-22 | 2023-01-17 | Biolite, Inc. | Polygala extract for the treatment of major depressive disorder |
| MX2024002602A (es) * | 2021-08-31 | 2024-04-19 | Ethismos Res Inc | Métodos para prevenir y tratar el dolor y síntomas asociados. |
| CN116813547A (zh) * | 2023-06-29 | 2023-09-29 | 爱斯特（成都）生物制药股份有限公司 | 一种制备3-氮杂双环[3，2，1]辛烷盐酸盐的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65843A (en) * | 1977-08-11 | 1986-12-31 | American Cyanamid Co | Pharmaceutical compositions for the treatment of depression containing 3-aza-bicyclo(3.1.0)hexane derivatives and certain novel compounds of this type |
| US6372919B1 (en) * | 2001-01-11 | 2002-04-16 | Dov Pharmaceutical, Inc. | (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent |
| ZA200701570B (en) * | 2004-08-18 | 2008-08-27 | Dov Pharmaceutical Inc | Novel polymorphs of azabicyclohexane |
| US20070043100A1 (en) * | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
| TW200735878A (en) * | 2005-11-18 | 2007-10-01 | Astrazeneca Ab | Pharmaceutical compositions |
| US20140228421A1 (en) * | 2011-09-07 | 2014-08-14 | Anthony McKinney | Methods For Inhibiting Native And Promiscuous Uptake Of Monoamine Neurotransmitters |
| US20130123238A1 (en) * | 2011-11-16 | 2013-05-16 | Anthony Alexander McKINNEY | Use of (+)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane to treat addictive and alcohol-related disorders |
-
2011
- 2011-12-02 BR BR112013013572A patent/BR112013013572A2/pt active Search and Examination
- 2011-12-02 US US13/310,694 patent/US20120258994A1/en not_active Abandoned
- 2011-12-02 WO PCT/US2011/063193 patent/WO2012075473A1/en not_active Ceased
- 2011-12-02 AU AU2011336318A patent/AU2011336318A1/en not_active Abandoned
- 2011-12-02 CA CA2834713A patent/CA2834713A1/en not_active Abandoned
- 2011-12-02 JP JP2013542235A patent/JP2013544850A/ja active Pending
- 2011-12-02 KR KR1020137017462A patent/KR20140053822A/ko not_active Ceased
- 2011-12-02 EP EP11844214.4A patent/EP2646019A4/en not_active Withdrawn
-
2013
- 2013-06-20 US US13/923,016 patent/US20140039029A1/en not_active Abandoned
-
2017
- 2017-01-05 JP JP2017000485A patent/JP2017114861A/ja active Pending
- 2017-10-13 US US15/783,596 patent/US20180256542A1/en not_active Abandoned
-
2018
- 2018-09-21 JP JP2018177184A patent/JP2019031502A/ja active Pending
- 2018-12-28 US US16/234,874 patent/US20190358199A1/en not_active Abandoned
-
2020
- 2020-09-30 US US17/039,064 patent/US20210161863A1/en not_active Abandoned
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