JP2013543899A - ６−ｏ−（４−ジメチルアミノエトキシ）シンナモイルフマギロールの非連日投与を用いた肥満の治療 - Google Patents

６−ｏ−（４−ジメチルアミノエトキシ）シンナモイルフマギロールの非連日投与を用いた肥満の治療 Download PDF

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JP2013543899A
JP2013543899A JP2013541073A JP2013541073A JP2013543899A JP 2013543899 A JP2013543899 A JP 2013543899A JP 2013541073 A JP2013541073 A JP 2013541073A JP 2013541073 A JP2013541073 A JP 2013541073A JP 2013543899 A JP2013543899 A JP 2013543899A
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patient
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pharmaceutically acceptable
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JP2013543899A5 (enExample
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ヒューズ，トーマス，イー．
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Larimar Therapeutics Inc
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Zafgen Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013541073A 2010-11-29 2011-11-29 ６−ｏ−（４−ジメチルアミノエトキシ）シンナモイルフマギロールの非連日投与を用いた肥満の治療 Pending JP2013543899A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41769210P 2010-11-29 2010-11-29
US61/417,692 2010-11-29
US201161500662P 2011-06-24 2011-06-24
US61/500,662 2011-06-24
PCT/US2011/062413 WO2012075020A1 (en) 2010-11-29 2011-11-29 Treatment of obesity using non-daily administration of 6 - 0 - (4 - dimethylaminoethoxy) cinnamoyl fumagillol

Publications (2)

Publication Number Publication Date
JP2013543899A true JP2013543899A (ja) 2013-12-09
JP2013543899A5 JP2013543899A5 (enExample) 2015-01-08

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JP2013541073A Pending JP2013543899A (ja) 2010-11-29 2011-11-29 ６−ｏ−（４−ジメチルアミノエトキシ）シンナモイルフマギロールの非連日投与を用いた肥満の治療

Country Status (10)

Country Link
US (6) US9173865B2 (enExample)
EP (1) EP2646016B1 (enExample)
JP (1) JP2013543899A (enExample)
KR (1) KR20140009273A (enExample)
CN (1) CN103379905A (enExample)
AU (1) AU2011336785A1 (enExample)
BR (1) BR112013013411A2 (enExample)
CA (1) CA2819251A1 (enExample)
MX (1) MX2013005989A (enExample)
WO (1) WO2012075020A1 (enExample)

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US9173956B2 (en) * 2013-04-10 2015-11-03 Syndevrx, Inc. METAP2 inhibitors and methods of treating obesity
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Also Published As

Publication number Publication date
BR112013013411A2 (pt) 2016-09-13
US20160243073A1 (en) 2016-08-25
US20140045935A1 (en) 2014-02-13
CN103379905A (zh) 2013-10-30
WO2012075020A1 (en) 2012-06-07
US8980946B2 (en) 2015-03-17
US20180221328A1 (en) 2018-08-09
US20140045934A1 (en) 2014-02-13
US20150209321A1 (en) 2015-07-30
US20140051752A1 (en) 2014-02-20
US9173865B2 (en) 2015-11-03
EP2646016B1 (en) 2017-05-17
MX2013005989A (es) 2013-08-21
KR20140009273A (ko) 2014-01-22
AU2011336785A1 (en) 2013-06-20
US9000035B2 (en) 2015-04-07
CA2819251A1 (en) 2012-06-07
EP2646016A1 (en) 2013-10-09

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